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Your search keyword '"Ohkubo, Yu"' showing total 16 results
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16 results on '"Ohkubo, Yu"'

6. Quality of palliative radiotherapy assessed using quality indicators: a multicenter survey†

Author

Saito, Tetsuo, Shikama, Naoto, Takahashi, Takeo, Nakamura, Naoki, Mori, Takashi, Nakajima, Kaori, Koizumi, Masahiko, Sekii, Shuhei, Ebara, Takeshi, Kiyohara, Hiroki, Higuchi, Keiko, Yorozu, Atsunori, Nishimura, Takeshi, Ejima, Yasuo, Harada, Hideyuki, Araki, Norio, Miwa, Misako, Yamada, Kazunari, Kawamoto, Terufumi, Imano, Nobuki, Heianna, Joichi, Nozaki, Miwako, Wada, Yuki, Ohkubo, Yu, Uchida, Nobue, Watanabe, Miho, Kosugi, Takashi, Miyazawa, Kazunari, Yasuda, Shigeo, and Onishi, Hiroshi

Abstract

We sought to identify potential evidence-practice gaps in palliative radiotherapy using quality indicators (QIs), previously developed using a modified Delphi method. Seven QIs were used to assess the quality of radiotherapy for bone metastases (BoM) and brain metastases (BrM). Compliance rate was calculated as the percentage of patients for whom recommended medical care was conducted. Random effects models were used to estimate the pooled compliance rates. Of the 39 invited radiation oncologists, 29 (74%) from 29 centers participated in the survey; 13 (45%) were academic and 16 (55%) were non-academic hospitals. For the QIs, except for BoM-4, the pooled compliance rates were higher than 80%; however, for at least some of the centers, the compliance rate was lower than these pooled rates. For BoM-4 regarding steroid use concurrent with radiotherapy for malignant spinal cord compression, the pooled compliance rate was as low as 32%. For BoM-1 regarding the choice of radiation schedule, the compliance rate was higher in academic hospitals than in non-academic hospitals (P= 0.021). For BrM-3 regarding the initiation of radiotherapy without delay, the compliance rate was lower in academic hospitals than in non-academic hospitals (P= 0.016). In conclusion, overall, compliance rates were high; however, for many QIs, practice remains to be improved in at least some centers. Steroids are infrequently used concurrently with radiotherapy for malignant spinal cord compression.

Published
2024
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15. Adenoid cystic carcinoma of the orbit without lacrimal gland involvement and with intracranial extension: A case report.

Author

Ohkubo Y, Okubo T, Asari Y, Matsuzaka Y, Kitaguchi M, Shiota S, Fujita R, Okamoto K, Obata H, Kishida Y, and Nagao T

Abstract

We present a 76-year-old female with a 6-year history of decreased vision in the right eye and right-sided facial neuralgia. She had a T1 isointense and T2 isointense enhancing lesion in the right orbit and the middle cranial fossa on MRI examination. Granulomatous disease or meningioma was suspected, however, after removal, the tumor was identified by pathology as adenoid cystic carcinoma (ACC). The tumor has no radiological and clinical lacrimal grand involvement. ACC shows a slow and indolent growth pattern but is associated with poor long-term outcomes, mainly due to perineural invasion, local control failure, and distant metastasis. This case highlights the importance of a pathologic diagnosis and early intervention in similar presentations., (© 2023 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)

Published
2023
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16. Repetitive Painting (REPEAT) Irradiation in Stereotactic Radiotherapy Using Helical Tomotherapy.

Author

Ohkubo YU, Kumazawa T, Hirai R, and Noda SE

Subjects
Dose Fractionation, Radiation, Humans, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Radiosurgery, Radiotherapy, Intensity-Modulated
Abstract

Background/aim: Stereotactic radiotherapy (SRT) for spine metastases with helical tomotherapy requires a long irradiation time due to the high dose per fraction. Since helical tomotherapy can neither confirm nor correct the position during irradiation, a plan with a long irradiation time cannot be used in actual clinical practice, given the intra-fractional motion error. To address this problem, we devised a method called REPEAT irradiation., Patients and Methods: REPEtitive pAinTing (REPEAT) irradiation is a method of dividing the irradiation for a given fraction per day into several sessions and performing the irradiation after position correction using mega-voltage computed tomography images for each session. In order to evaluate how REPEAT irradiation changes irradiation time and the dose-volume histogram (DVH), a planning study with helical tomotherapy was conducted using CT images of a patient with lumbar spine metastasis., Results: In this case, we found that dividing 3 irradiation fractions into 3 sessions per day (i.e., 9 fractions=9 sessions in 3 days) using REPEAT irradiation shortened the irradiation time per session and simultaneously improved dose-volume histogram parameters., Conclusion: Although the optimal number of sessions may differ depending on the patient's condition, the fixing method, the irradiation site, and the calculation parameters, REPEAT irradiation does not require any special equipment and is a simple practical treatment method., (Copyright © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)

Published
2022
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