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2. Robotic Appendectomy

Author

Coletta, Diego, Patriti, Alberto, Milone, Marco, editor, Agresta, Ferdinando, editor, Guerrieri, Mario, editor, Petz, Wanda, editor, Arezzo, Alberto, editor, and Casarano, Salvatore, editor

Published
2024
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4. Mechanical bowel preparation in elective colorectal surgery: a propensity score-matched analysis of the Italian colorectal anastomotic leakage (iCral) study group prospective cohorts

Author

Catarci, Marco, Guadagni, Stefano, Masedu, Francesco, Ruffo, Giacomo, Viola, Massimo Giuseppe, Borghi, Felice, Baldazzi, Gianandrea, Pirozzi, Felice, Delrio, Paolo, Garulli, Gianluca, Marini, Pierluigi, Patriti, Alberto, Campagnacci, Roberto, Sica, Giuseppe, Caricato, Marco, Montemurro, Leonardo Antonio, Ciano, Paolo, Benedetti, Michele, Guercioni, Gianluca, and Scatizzi, Marco

Published
2024
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5. Surgical Techniques and Related Perioperative Outcomes After Robot-assisted Minimally Invasive Gastrectomy (RAMIG): Results From the Prospective Multicenter International Ugira Gastric Registry

Author

de Jongh, Cas, Cianchi, Fabio, Kinoshita, Takahiro, Kingma, Feike, Piccoli, Micaela, Dubecz, Attila, Kouwenhoven, Ewout, van Det, Marc, Mala, Tom, Coratti, Andrea, Ubiali, Paolo, Turner, Paul, Kish, Pursnani, Borghi, Felice, Immanuel, Arul, Nilsson, Magnus, Rouvelas, Ioannis, Holzen, Jens P., Rouanet, Philippe, Saint-Marc, Olivier, Dussart, David, Patriti, Alberto, Bazzocchi, Francesca, van Etten, Boudewijn, Haveman, Jan W., DePrizio, Marco, Sabino, Flávio, Viola, Massimo, Berlth, Felix, Grimminger, Peter P., Roviello, Franco, van Hillegersberg, Richard, Ruurda, Jelle, Barbato, Giuseppe, Takeuchi, Tamae, Yura, Masahiro, Pecchini, Francesca, Mullineris, Barbara, Kemeter, Melissa, Giulini, Luca, Førland, Dag, Di Marino, Michele, Tribuzi, Angela, Maffeis, Federica, Velkoski, Jaqueline, Sarantitis, Ioannis, Marano, Alessandra, Robella, Manuela, Jaretzke, Helen, Ri, Motonari, Juratli, Mazen, Mourregot, Anne, Petrelli, Filippo, Biancafarina, Alessia, Barbieri, Vittoria, Uzun, Eren, Marano, Luigi, d’Ignazio, Alessia, and Resca, Luca

Published
2024
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9. Sutureless Repair for Open Treatment of Inguinal Hernia: Three Techniques in Comparison

Author

Enke Baldini, Eleonora Lori, Carola Morini, Luigi Palla, Diego Coletta, Giuseppe M. De Luca, Giorgio Giraudo, Sergio G. Intini, Bruno Perotti, Angelo Sorge, Giampaolo Sozio, Marco Arganini, Elsa Beltrami, Daniele Pironi, Massimo Ranalli, Cecilia Saviano, Alberto Patriti, Sofia Usai, Nicola Vernaccini, Francesco Vittore, Vito D’Andrea, Priscilla Nardi, Salvatore Sorrenti, and Piergaspare Palumbo

Subjects
inguinal hernia, sutureless repair, postoperative complications, antithrombotic therapy, Medicine
Abstract

Currently, groin hernia repair is mostly performed with application of mesh prostheses fixed with or without suture. However, views on safety and efficacy of different surgical approaches are still partly discordant. In this multicentre retrospective study, three sutureless procedures, i.e., mesh fixation with glue, application of self-gripping mesh, and Trabucco’s technique, were compared in 1034 patients with primary unilateral non-complicated inguinal hernia subjected to open anterior surgery. Patient-related features, comorbidities, and drugs potentially affecting the intervention outcomes were also examined. The incidence of postoperative complications, acute and chronic pain, and time until discharge were assessed. A multivariate logistic regression was used to compare the odds ratio of the surgical techniques adjusting for other risk factors. The application of standard/heavy mesh, performed in the Trabucco’s technique, was found to significantly increase the odds ratio of hematomas (p = 0.014) and, most notably, of acute postoperative pain (p < 0.001). Among the clinical parameters, antithrombotic therapy and large hernia size were independent risk factors for hematomas and longer hospital stay, whilst small hernias were an independent predictor of pain. Overall, our findings suggest that the Trabucco’s technique should not be preferred in patients with a large hernia and on antithrombotic therapy.

Published
2024
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11. Patient-Reported Outcomes and Return to Intended Oncologic Therapy After Colorectal Enhanced Recovery Pathway

Author

The Italian ColoRectal Anastomotic Leakage (iCral3) study group, Marco Catarci, MD, FACS, Giacomo Ruffo, MD, Massimo Giuseppe Viola, MD, Ferdinando Ficari, MD, Paolo Delrio, MD, Felice Pirozzi, MD, Felice Borghi, MD, Raffaele De Luca, MD, Alberto Patriti, MD, Gianluca Garulli, MD, Walter Siquini, MD, Stefano D’Ugo, MD, PhD, FEBS, FACS, Stefano Scabini, MD, Marco Caricato, MD, FACS, Giusto Pignata, MD, Andrea Liverani, MD, Roberto Campagnacci, MD, Pierluigi Marini, MD, Ugo Elmore, MD, Francesco Corcione, MD, Roberto Santoro, MD, Massimo Carlini, MD, FACS, Antonio Giuliani, MD, Mario Sorrentino, MD, Giovanni Ferrari, MD, Gianandrea Baldazzi, MD, Alberto Di Leo, MD, Augusto Verzelli, MD, Giuseppe Sica, MD, Stefano Rausei, MD, Davide Cavaliere, MD, Gian Luca Baiocchi, MD, FACS, Marco Milone, MD, Giovanni Ciaccio, MD, Giovanni Domenico Tebala, MD, FACS, FRCS, Marco Scatizzi, MD, Luigi Boni, MD, FACS, Stefano Mancini, MD, Mario Guerrieri, MD, Roberto Persiani, MD, Andrea Lucchi, MD, FACS, Dario Parini, MD, Antonino Spinelli, MD, Michele Genna, MD, Vincenzo Bottino, MD, Andrea Coratti, MD, Dario Scala, MD, Andrea Muratore, MD, Maurizio Pavanello, MD, Umberto Rivolta, MD, Micaela Piccoli, MD, FACS, Carlo Talarico, MD, Alessandro Carrara, MD, Stefano Guadagni, MD, Mauro Totis, MD, Franco Roviello, MD, Alessandro Anastasi, MD, Gianluca Guercioni, MD, Giuseppe Maria Ettorre, MD, Mauro Montuori, MD, Pierpaolo Mariani, MD, Nicolò de Manzini, MD, Annibale Donini, MD, Mariano Fortunato Armellino, MD, Lucio Taglietti, MD, Gabriele Anania, MD, Mariantonietta Di Cosmo, MD, Carlo Vittorio Feo, MD, Paolo Millo, MD, Corrado Pedrazzani, MD, Silvio Guerriero, MD, Andrea Costanzi, MD, Nereo Vettoretto, MD, Federico Marchesi, MD, Massimo Basti, MD, Graziano Longo, MD, Moreno Cicetti, MD, Paolo Ciano, MD, Michele Benedetti, MD, Leonardo Antonio Montemurro, MD, Maria Sole Mattei, MD, Elena Belloni, MD, Elisa Bertocchi, MD, Gaia Masini, MD, Amedeo Altamura, MD, Francesco Rubichi, MD, Francesco Giudici, MD, Fabio Cianchi, MD, Gabriele Baldini, MD, Ugo Pace, MD, Andrea Fares Bucci, MD, Antonio Sciuto, MD, Desirée Cianflocca, MD, Marco Migliore, MD, Michele Simone, MD, Marcella Lodovica Ricci, MD, Francesco Monari, MD, Alessandro Cardinali, MD, Massimo Sartelli, MD, Marcello Spampinato, MD, PhD, FEBS (HPB), Alessandra Aprile, MD, Domenico Soriero, MD, Gabriella Teresa Capolupo, MD, FACS, Jacopo Andreuccetti, MD, Ilaria Canfora, MD, Andrea Scarinci, MD, Angela Maurizi, MD, Grazia Maria Attinà, MD, Giulia Maggi, MD, Umberto Bracale, MD, Roberto Peltrini, MD, Pietro Amodio, MD, Domenico Spoletini, MD, PhD, FACS, Rosa Marcellinaro, MD, Giovanni Del Vecchio, MD, Massimo Stefanoni, MD, Carmelo Magistro, MD, Diletta Cassini, MD, Lorenzo Crepaz, MD, Andrea Budassi, MD, Bruno Sensi, MD, Silvia Tenconi, MD, Leonardo Solaini, MD, Giorgio Ercolani, MD, Sarah Molfino, MD, Giovanni Domenico De Palma, MD, Paolo Locurto, MD, Antonio Di Cintio, MD, Lorenzo Pandolfini, MD, Alessandro Falsetto, MD, Elisa Cassinotti, MD, Andrea Sagnotta, MD, PhD, Monica Ortenzi, MD, Alberto Biondi, MD, Giacomo Martorelli, MD, Maurizio De Luca, MD, Francesco Carrano, MD, Annalisa Maroli, PhD, Francesca Fior, MD, Antonio Ferronetti, MD, Giuseppe Giuliani, MD, Roberto Benigni, MD, Graziella Marino, MD, Patrizia Marsanic, MD, Nicoletta Sveva Pipitone Federico, MD, Carlo Di Marco, MD, Camillo Leonardo Bertoglio, MD, PhD, Francesca Pecchini, MD, Vincenzo Greco, MD, Michele Motter, MD, Giuseppe Tirone, MD, Marco Clementi, MD, Nicolò Tamini, MD, Riccardo Piagnerelli, MD, Giuseppe Canonico, MD, Simone Cicconi, MD, Marco Colasanti, MD, Enrico Pinotti, MD, Roberta Carminati, MD, Edoardo Osenda, MD, Luigina Graziosi, MD, Ciro De Martino, MD, Giovanna Ioia, MD, Arianna Birindelli, MD, Matteo Chiozza, MD, Daniele Zigiotto, MD, Fioralba Pindozzi, MD, Manuela Grivon, MD, Cristian Conti, MD, Lorenzo Organetti, MD, Michela Monteleone, MD, Emanuele Botteri, MD, Giorgio Dalmonte, MD, Diletta Frazzini, MD, Simone Santoni, MD, Gabriele La Gioia, MD, and Diana Giannarelli, MS, PhD

Subjects
Surgery, RD1-811
Abstract

Objective:. To evaluate the influence of enhanced recovery pathway (ERP) on patient-reported outcome measures (PROMs) and return to intended oncologic therapy (RIOT) after colorectal surgery. Background:. ERP improves early outcomes after colorectal surgery; however, little is known about its influence on PROMs and on RIOT. Methods:. Prospective multicenter enrollment of patients who underwent colorectal resection with anastomosis was performed, recording variables related to patient-, institution-, procedure-level data, adherence to the ERP, and outcomes. The primary endpoints were PROMs (administered before surgery, at discharge, and 6 to 8 weeks after surgery) and RIOT after surgery for malignancy, defined as the intended oncologic treatment according to national guidelines and disease stage, administered within 8 weeks from the index operation, evaluated through multivariate regression models. Results:. The study included 4529 patients, analyzed for PROMs, 1467 of which were analyzed for RIOT. Compared to their baseline preoperative values, all PROMs showed significant worsening at discharge and improvement at late evaluation. PROMs values at discharge and 6 to 8 weeks after surgery, adjusted through a generalized mixed regression model according to preoperative status and other variables, showed no association with ERP adherence rates. RIOT rates (overall 54.5%) were independently lower by aged > 69 years, ASA Class III, open surgery, and presence of major morbidity; conversely, they were independently higher after surgery performed in an institutional ERP center and by ERP adherence rates > median (69.2%). Conclusions:. Adherence to the ERP had no effect on PROMs, whereas it independently influenced RIOT rates after surgery for colorectal cancer.

Published
2023
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12. Patient-Reported Outcomes and Return to Intended Oncologic Therapy After Colorectal Enhanced Recovery Pathway: The iCral3 Prospective Study

Author

Catarci, Marco, Ruffo, Giacomo, Viola, Massimo Giuseppe, Ficari, Ferdinando, Delrio, Paolo, Pirozzi, Felice, Borghi, Felice, De Luca, Raffaele, Patriti, Alberto, Garulli, Gianluca, Siquini, Walter, D’Ugo, Stefano, Scabini, Stefano, Caricato, Marco, Pignata, Giusto, Liverani, Andrea, Campagnacci, Roberto, Marini, Pierluigi, Elmore, Ugo, Corcione, Francesco, Santoro, Roberto, Carlini, Massimo, Giuliani, Antonio, Sorrentino, Mario, Ferrari, Giovanni, Baldazzi, Gianandrea, Di Leo, Alberto, Verzelli, Augusto, Sica, Giuseppe, Rausei, Stefano, Cavaliere, Davide, Baiocchi, Gian Luca, Milone, Marco, Ciaccio, Giovanni, Tebala, Giovanni Domenico, Scatizzi, Marco, Boni, Luigi, Mancini, Stefano, Guerrieri, Mario, Persiani, Roberto, Lucchi, Andrea, Parini, Dario, Spinelli, Antonino, Genna, Michele, Bottino, Vincenzo, Coratti, Andrea, Scala, Dario, Muratore, Andrea, Pavanello, Maurizio, Rivolta, Umberto, Piccoli, Micaela, Talarico, Carlo, Carrara, Alessandro, Guadagni, Stefano, Totis, Mauro, Roviello, Franco, Anastasi, Alessandro, Guercioni, Gianluca, Maria Ettorre, Giuseppe, Montuori, Mauro, Mariani, Pierpaolo, de Manzini, Nicolò, Donini, Annibale, Armellino, Mariano Fortunato, Taglietti, Lucio, Anania, Gabriele, Di Cosmo, Mariantonietta, Feo, Carlo Vittorio, Millo, Paolo, Pedrazzani, Corrado, Guerriero, Silvio, Costanzi, Andrea, Vettoretto, Nereo, Marchesi, Federico, Basti, Massimo, Longo, Graziano, Cicetti, Moreno, Ciano, Paolo, Benedetti, Michele, Montemurro, Leonardo Antonio, Mattei, Maria Sole, Belloni, Elena, Bertocchi, Elisa, Masini, Gaia, Altamura, Amedeo, Rubichi, Francesco, Giudici, Francesco, Cianchi, Fabio, Baldini, Gabriele, Pace, Ugo, Bucci, Andrea Fares, Sciuto, Antonio, Cianflocca, Desirée, Migliore, Marco, Simone, Michele, Ricci, Marcella Lodovica, Monari, Francesco, Cardinali, Alessandro, Sartelli, Massimo, Spampinato, Marcello, Aprile, Alessandra, Soriero, Domenico, Capolupo, Gabriella Teresa, Andreuccetti, Jacopo, Canfora, Ilaria, Scarinci, Andrea, Maurizi, Angela, Attinà, Grazia Maria, Maggi, Giulia, Bracale, Umberto, Peltrini, Roberto, Amodio, Pietro, Spoletini, Domenico, Marcellinaro, Rosa, Del Vecchio, Giovanni, Stefanoni, Massimo, Magistro, Carmelo, Cassini, Diletta, Crepaz, Lorenzo, Budassi, Andrea, Sensi, Bruno, Tenconi, Silvia, Solaini, Leonardo, Ercolani, Giorgio, Molfino, Sarah, De Palma, Giovanni Domenico, Locurto, Paolo, Di Cintio, Antonio, Pandolfini, Lorenzo, Falsetto, Alessandro, Cassinotti, Elisa, Sagnotta, Andrea, Ortenzi, Monica, Biondi, Alberto, Martorelli, Giacomo, De Luca, Maurizio, Carrano, Francesco, Maroli, Annalisa, Fior, Francesca, Ferronetti, Antonio, Giuliani, Giuseppe, Benigni, Roberto, Marino, Graziella, Marsanic, Patrizia, Pipitone Federico, Nicoletta Sveva, Di Marco, Carlo, Bertoglio, Camillo Leonardo, Pecchini, Francesca, Greco, Vincenzo, Motter, Michele, Tirone, Giuseppe, Clementi, Marco, Tamini, Nicolò, Piagnerelli, Riccardo, Canonico, Giuseppe, Cicconi, Simone, Colasanti, Marco, Pinotti, Enrico, Carminati, Roberta, Osenda, Edoardo, Graziosi, Luigina, De Martino, Ciro, Ioia, Giovanna, Birindelli, Arianna, Chiozza, Matteo, Zigiotto, Daniele, Pindozzi, Fioralba, Grivon, Manuela, Conti, Cristian, Organetti, Lorenzo, Monteleone, Michela, Botteri, Emanuele, Dalmonte, Giorgio, Frazzini, Diletta, Santoni, Simone, La Gioia, Gabriele, and Giannarelli, Diana

Published
2023
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13. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author

Alagna, V., Amodio, P., Anania, G., Angeloni, R., Arici, E., Baiocchi, G., Baraghini, M., Benedetti, M., Bertocchi, E., Borghi, F., Brisinda, G., Campagnacci, R., Capolupo, G.T., Caricato, M., Carrara, A., Ceccaroni, M., Chiarello, M.M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, M., Delrio, P., Di Cesare, T., Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, A., Longo, G., Lucchi, A., Luzzi, A.P., Macarone Palmieri, R., Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, G., Tirone, G., Tomassini, F., Vettoretto, N., Zigiotto, D., Guerra, Francesco, Petrelli, Filippo, Greco, Paola Antonella, Sisti, Valerio, Catarci, Marco, Montalti, Roberto, and Patriti, Alberto

Published
2021
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14. Sutureless Repair for Open Treatment of Inguinal Hernia: Three Techniques in Comparison

Author

Baldini, Enke, primary, Lori, Eleonora, additional, Morini, Carola, additional, Palla, Luigi, additional, Coletta, Diego, additional, De Luca, Giuseppe M., additional, Giraudo, Giorgio, additional, Intini, Sergio G., additional, Perotti, Bruno, additional, Sorge, Angelo, additional, Sozio, Giampaolo, additional, Arganini, Marco, additional, Beltrami, Elsa, additional, Pironi, Daniele, additional, Ranalli, Massimo, additional, Saviano, Cecilia, additional, Patriti, Alberto, additional, Usai, Sofia, additional, Vernaccini, Nicola, additional, Vittore, Francesco, additional, D’Andrea, Vito, additional, Nardi, Priscilla, additional, Sorrenti, Salvatore, additional, and Palumbo, Piergaspare, additional

Published
2024
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16. ICG fluorescence imaging in colorectal surgery: a snapshot from the ICRAL study group

Author

Baiocchi, Gian Luca, Guercioni, Gianluca, Vettoretto, Nereo, Scabini, Stefano, Millo, Paolo, Muratore, Andrea, Clementi, Marco, Sica, Giuseppe, Delrio, Paolo, Longo, Graziano, Anania, Gabriele, Barbieri, Vittoria, Amodio, Pietro, Di Marco, Carlo, Baldazzi, Gianandrea, Garulli, Gianluca, Patriti, Alberto, Pirozzi, Felice, De Luca, Raffaele, Mancini, Stefano, Pedrazzani, Corrado, Scaramuzzi, Matteo, Scatizzi, Marco, Taglietti, Lucio, Motter, Michele, Ceccarelli, Graziano, Totis, Mauro, Gennai, Andrea, Frazzini, Diletta, Di Mauro, Gianluca, Capolupo, Gabriella Teresa, Crafa, Francesco, Marini, Pierluigi, Ruffo, Giacomo, Persiani, Roberto, Borghi, Felice, de Manzini, Nicolò, and Catarci, Marco

Published
2021
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17. Crohn’s Disease and Jejunal Artery Aneurysms: A Report of the First Case and a Review of the Literature

Author

Paolo Vincenzi, Diletta Gaudenzi, Luca Mulazzani, Alberto Rebonato, and Alberto Patriti

Subjects
visceral artery aneurysms, jejunal artery aneurysms, ileal artery aneurysms, visceral artery pseudoaneurysms, inflammatory bowel disease, Crohn’s disease, Medicine (General), R5-920
Abstract

Background and Objectives: Jejunal artery (JA) and ileal artery (IA) aneurysms constitute less than 3% of all visceral artery aneurysms (VAAs), carrying a risk of rupture as high as 30%, and a mortality of 20%. Though many etiologies have been reported in the literature, no mention exists on a causal association between these aneurysms and inflammatory bowel diseases (IBD). We present the first case of a JA aneurysm related to Crohn’s Disease (CD) together with a review of the literature. Materials and Methods: A 74-year-old male presenting with CD intestinal relapse and an incidental finding at the computed tomography enterography (CTE) of a 53 × 47 × 25mm apparently intact JA pseudoaneurysm, arising from the first and second jejunal branches, underwent coil embolization followed by small bowel resection, with an uneventful outcome. We also included the review of literature on JA and IA aneurysms, analyzing all reports published in PubMed and Scopus from 1943 to July 2022. Results: 60 manuscripts with 103 cases of JA and IA aneurysms in 100 patients were identified. Among cases with available data, 34 (33.0%) presented acutely with rupture, 45 (43.7%) were described as non-ruptured. 83 (80.6%), and 14 (13.6%) were JA and IA aneurysms, respectively, having a median size of 15 (range:3.5–52) mm. Atherosclerosis (16.5%), infections (10.7%), and vasculitides/connective tissue disorders (9.7%) represented the main causes mentioned. Mean age was 53.6 (±19.2) years, male patients being 59.4%. One third of patients (32.4%) were asymptomatic. Overall, treatment was indicated in 63% of patients, with surgery and endovascular procedures performed in 61.9% and 38.1% cases, respectively. The technical success rate of endovascular treatment (EVT) was 95.8%. The mortality rate was 11.8%, being higher (21.2%) in the rupture group. Conclusions: The prompt treatment accomplished in our case granted a successful outcome. JA and IA aneurysms should be included among local complications of IBD. Considering their high potential for rupture, regardless of size, a low threshold for endovascular or surgical treatment should be applied.

Published
2022
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19. Robot-assisted laparoscopic total and partial gastric resection with D2 lymph node dissection for adenocarcinoma

Author

Patriti, Alberto, Ceccarelli, Graziano, Bellochi, Raffaele, Bartoli, Alberto, Spaziani, Alessandro, Di Zitti, Lelio, and Casciola, Luciano

Abstract

Abstract: Background: Lymph node dissection and esophageal anastomosis, considered the more demanding steps of laparoscopic gastrectomy for gastric adenocarcinoma, can be performed with the use of a remote-controlled robot. Methods: Thirteen patients with a histologically proved gastric cancer (six stage I, six stage II, and one stage III) were enrolled in a prospective study to assess feasibility and safety of the Da Vinci surgical system in total and partial gastrectomy with extended lymph node dissection. Outcome measures were conversion rate, intra- and postoperative morbidity and mortality, operative time, blood loss, number of lymph nodes harvested, and macroscopic and microscopic evaluation of resection margins. Results: Eight distal, four total, and one proximal laparoscopic gastrectomies were completed without conversion. Extended lymph node dissection, and esophagojejunal and esophagogastric anastomoses were successfully carried out using the da Vinci System. Mean operative time was 286 ± 32.6 min and blood loss was 103 ± 87.5 ml. Mean number of nodes retrieved was 28.1 ± 8.3 and all resection margins were negative. There was no mortality. Trocar bleeding requiring laparoscopy was the only major complication encountered. No recurrence occurred during a mean follow-up time of 12.2 ± 4.5 months. Conclusions: Robot-assisted laparoscopic lymph node dissection and esophageal anastomosis are feasible and safe. Longer follow-up time and randomized studies are needed to evaluate long-term outcome and clinical advantages of this new technology.

Published
2024
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20. Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

Author

Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nicholas, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Boris, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Rigers, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, Celentano, Valerio, Institut Català de la Salut, [Rottoli M, Gori A, Pellino G] Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. [Pellino G] Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Flacco ME, Martellucci C] Department of Environmental and Preventive Sciences, University of Ferrara, Ferrara, Italy. [Spinelli A] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. Colorectal Surgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy, Vall d'Hebron Barcelona Hospital Campus, Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nichola, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Bori, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Riger, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, and Celentano, Valerio

Subjects
Adult, Male, Settore MED/18 - CHIRURGIA GENERALE, Otros calificadores::/diagnóstico [Otros calificadores], Hospitals, Community, colorectal cancer, Community, advanced stage, COVID-19 (Malaltia), Cohort Studies, Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [DISEASES], Retrospective Studie, Other subheadings::/diagnosis [Other subheadings], virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], Humans, Pandemics, Aged, Retrospective Studies, Pandemic, SARS-CoV-2, COVID-19, Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], General Medicine, neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales [ENFERMEDADES], Hospitals, Recte - Càncer - Diagnòstic, Settore MED/18, Italy, Còlon - Càncer - Diagnòstic, Cohort Studie, Colorectal Neoplasms, Human
Abstract

ImportanceDelays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis.ObjectiveTo evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer.Design, Setting, and ParticipantsThis retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery.ExposuresAny type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections.Main Outcomes and MeasuresThe primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable.ResultsA total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95% CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95% CI, 1.15-1.53; P P = .03).Conclusions and RelevanceThis cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients.

Published
2022

22. The role of resection for melanoma metastases to the pancreas

Author

Guerra, Francesco, primary, Coletta, Diego, additional, Deutsch, Gary B., additional, Giuliani, Giuseppe, additional, Patriti, Alberto, additional, Fischer, Trevan D., additional, Coratti, Andrea, additional, Serafini, Simone, additional, Surjan, Rodrigo, additional, Milanetto, Anna C., additional, and Campra, Donata, additional

Published
2022
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24. Uniportal robotic‐assisted thoracoscopic surgery for early‐stage lung cancer with the Da Vinci Xi: Initial experience of two cases

Author

Paolo Vincenzi, Felice Lo Faso, Emilio Eugeni, and Alberto Patriti

Subjects
Biophysics, Surgery, Computer Science Applications
Abstract

Minimally invasive surgery (MIS) techniques, currently considered the gold standard in the treatment of early-stage non-small cell lung cancer (NSCLC), are mainly represented by video-assisted thoracoscopic surgery (VATS), both uniportal and multiportal, and by robotic-assisted thoracoscopic surgery (RATS). While multiportal RATS has been accepted as a valid alternative to VATS, carrying the advantages of three-dimensional high-definition visualisation and improved maneuverability, very few reports exist in literature on the application of uniportal RATS (U-RATS). Therefore, we describe our initial experience with this recently developed method in the treatment of early-stage NSCLC.U-RATS was conducted through a single 4 cm long antero-lateral mini-thoracotomy (ALMT) in the sixth intercostal space at the mid-axillary line. Three 8 mm robotic trocars were positioned and connected, from back to front, to robotic arms as follows: 30° camera arm, robotic arm 2 (bipolar fenestrated grasper) and 1 (Maryland bipolar forceps). Assistant access was identified as the most anterior part of ALMT.Case 1: an 82-year-old woman (American Society of Anaesthesiologists [ASA III]) underwent a left S6 segmentectomy for a clinical stage IA2 NSCLC, complicated by an air leak that resolved spontaneously by postoperative day three (POD 3). Case 2: a 75-year-old man (ASA III) underwent an uncomplicated right lower lobectomy for a clinical stage IA3 NSCLC. Case 1 and 2 were discharged on POD 5 and 4, respectively.From what emerged in our small series, U-RATS with the Da Vinci Xi surgical system might be considered a safe, reliable, and effective alternative to other MIS techniques. Larger prospective studies are required to validate these findings.

Published
2022

25. Ostomy closure rate during COVID-19 pandemic: an Italian multicentre observational study

Author

Balla Andrea, Saraceno Federica, Di Saverio Salomone, Di Lorenzo Nicola, Lepiane Pasquale, Guerrieri Mario, Sileri Pierpaolo, Laura Agostinelli, Ferdinando Agresta, Gabriele Anania, Laura Antolino, Pietro Anoldo, Emanuele Botteri, Umberto Bracale, Fabio Carbone, Massimo Carlini, Francesco Maria Carrano, Giorgia Casadei, Diego Coletta, Francesco Crafa, Nicola de’Angelis, Paolo Delrio, Giovanni Domenico De Palma, Marcello Di Martino, Ugo Elmore, Lorenzo Gozzini, Michele Grieco, Giovanni Battista Levi Sandri, Edelweiss Licitra, Andrea Lucchi, Marco Massani, Riccardo Memeo, Marco Milone, Dario Oppici, Monica Ortenzi, Alberto Patriti, Francesca Pecchini, Roberto Peltrini, Micaela Piccoli, Adolfo Pisanu, Mauro Podda, Gilberto Poggioli, Maria Chiara Ranucci, Daniela Rega, Riccardo Rosati, Francesco Roscio, Matteo Rottoli, Roberto Santoro, Alberto Sartori, Antonino Spinelli, Serafino Vanella, Giovanni Vennarecci, Nereo Vettoretto, Balla, Andrea, Saraceno, Federica, Di Saverio, Salomone, Di Lorenzo, Nicola, Lepiane, Pasquale, Guerrieri, Mario, Sileri, Pierpaolo, Rosati, Riccardo, and Balla Andrea, Saraceno Federica, Di Saverio Salomone, Di Lorenzo Nicola, Lepiane Pasquale, Guerrieri Mario, Sileri Pierpaolo, Laura Agostinelli, Ferdinando Agresta, Gabriele Anania, Laura Antolino, Pietro Anoldo, Emanuele Botteri, Umberto Bracale, Fabio Carbone, Massimo Carlini, Francesco Maria Carrano, Giorgia Casadei, Diego Coletta, Francesco Crafa, Nicola de’Angelis, Paolo Delrio, Giovanni Domenico De Palma, Marcello Di Martino, Ugo Elmore, Lorenzo Gozzini, Michele Grieco, Giovanni Battista Levi Sandri, Edelweiss Licitra, Andrea Lucchi, Marco Massani, Riccardo Memeo, Marco Milone, Dario Oppici, Monica Ortenzi, Alberto Patriti, Francesca Pecchini, Roberto Peltrini, Micaela Piccoli, Adolfo Pisanu, Mauro Podda, Gilberto Poggioli, Maria Chiara Ranucci, Daniela Rega, Riccardo Rosati, Francesco Roscio, Matteo Rottoli, Roberto Santoro, Alberto Sartori, Antonino Spinelli, Serafino Vanella, Giovanni Vennarecci & Nereo Vettoretto

Subjects
Quality of life (QoL), Colostomy, Corona virus disease 2019 (COVID-19), Cost, Ileostomy, Ostomy, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surgery, Settore MED/18
Abstract

During the corona virus disease 2019 (COVID-19) pandemic, most of the surgical procedures were performed for emergencies or oncologic reasons to the detriment of the remaining elective procedures for benign conditions. Ileostomy or colostomy creation are sequelae of oncologic or emergency colorectal surgery, but their closure does not fall within the definition of oncologic or emergency surgery. The aim of this retrospective multicentre observational study is to report the impact of COVID-19 pandemic on the ostomy closure rate in Italy. Data regarding ileostomy and colostomy creation and closure from 24 Italian centres, during the study period (March 2020-February 2021) and during the control period (March 2019-February 2020) were collected. Three hospitals (12.5%) were COVID free. The number of colostomies and ileostomies created and closed in the same period was lower ( -18.8% and -30%, respectively) in the study period in comparison to the control period (p = 0.1915 and p = 0.0001, respectively), such as the ostomies closed in the analysed periods but created before (colostomy -36.2% and ileostomy -7.4%, p = 0.2211 and p = 0.1319, respectively). Overall, a 19.5% reduction in ostomies closed occurred in the study period. Based on the present study, a reduction in ostomy closure rate occurred in Italy between March 2020 and February 2021. During the pandemic, the need to change the clinical practice probably prolonged deterioration of quality of life in patients with ostomies, increasing number of stomas that will never be closed, and related management costs, even if these issues have not been investigated in this study.

Published
2022

27. Pathologic stage of ypT0N+ rectal cancers following neo-adjuvant treatment: clinical interpretation of an orphan status

Author

Lorenzon, Laura, primary, De Luca, Raffaele, additional, Santoro, Gloria, additional, Parini, Dario, additional, Rega, Daniela, additional, Mellano, Alfredo, additional, Vigorita, Vincenzo, additional, Jiménez-Rosellón, Raquel, additional, Sandin, Marta, additional, Andriola, Valeria, additional, Gallo, Gaetano, additional, Marino, Graziella, additional, Turati, Luca, additional, Marsanic, Patrizia, additional, Marano, Luigi, additional, Lucarini, Alessio, additional, Aprile, Alessandra, additional, Sagnotta, Andrea, additional, Biondi, Alberto, additional, D'Ugo, Domenico, additional, Delrio, Paolo, additional, Balducci, Genoveffa, additional, Montesi, Giampaolo, additional, Muratore, Andrea, additional, Ruano Poblador, Alejandro, additional, Persiani, Roberto, additional, Frasson, Matteo, additional, Roviello, Franco, additional, Vincenti, Leonardo, additional, Trompetto, Mario, additional, Torre, Giuseppe La, additional, Scala, Dario, additional, Sgroi, Giovanni, additional, Patriti, Alberto, additional, Simone, Michele, additional, Scabini, Stefano, additional, and Mancini, Stefano, additional

Published
2022
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28. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author

C. Di Marco, Gianluca Guercioni, G. Anania, Antonio Sciuto, Felice Pirozzi, P. Marini, Stefano Scabini, Marcello Ceccaroni, Ugo Pace, M. Pavanello, Alessandro Carrara, Elisa Arici, Federico Tomassini, Antonio Martino, Riccardo Angeloni, Alberto Patriti, B. Ruggeri, Lorenzo Pandolfini, A. Sagnotta, Marco Scatizzi, Elisa Bertocchi, R. Macarone Palmieri, Simone Cicconi, Angela Maurizi, D. Zigiotto, Marco Catarci, Gian Luca Baiocchi, G. Tirone, Paolo Delrio, Felice Borghi, Sarah Molfino, Marco Migliore, G. Brisinda, T. di Cesare, Stefano Mancini, M. Clementi, Paolo Ciano, G. Sica, Michele Motter, Vincenzo Alagna, Roberto Campagnacci, Simone Santoni, Andrea Pierre Luzzi, Giacomo Martorelli, Nereo Vettoretto, Andrea Muratore, Desiree Cianflocca, Maddalena Baraghini, S. Guadagni, M.M. Chiarello, Andrea Lucchi, Andrea Liverani, Valerio Sisti, Graziano Longo, Filippo Petrelli, Gianluca Garulli, Michele Benedetti, M. Lambertini, Pietro Maria Amodio, A. Falsetto, Francesco Guerra, Gabriella Teresa Capolupo, Paola Antonella Greco, Roberto Montalti, P. Marsanic, Marco Caricato, Giacomo Ruffo, Irene Marziali, Guerra, F., Petrelli, F., Greco, P. A., Sisti, V., Catarci, M., Montalti, R., Patriti, A., Alagna, V., Amodio, P., Anania, G., Angeloni, R., Arici, E., Baiocchi, G., Baraghini, M., Benedetti, M., Bertocchi, E., Borghi, F., Brisinda, G., Campagnacci, R., Capolupo, G. T., Caricato, M., Carrara, A., Ceccaroni, M., Chiarello, M. M., Cianflocca, D., Ciano, P., Cicconi, S., Clementi, M., Delrio, P., Di Cesare, T., Di Marco, C., Falsetto, A., Garulli, G., Guadagni, S., Guercioni, G., Lambertini, M., Liverani, A., Longo, G., Lucchi, A., Luzzi, A. P., Macarone Palmieri, R., Mancini, S., Marini, P., Marsanic, P., Martino, A., Martorelli, G., Marziali, I., Maurizi, A., Migliore, M., Molfino, S., Motter, M., Muratore, A., Pace, U., Pandolfini, L., Pavanello, M., Pirozzi, F., Ruffo, G., Ruggeri, B., Sagnotta, A., Santoni, S., Scabini, S., Scatizzi, M., Sciuto, A., Sica, G., Tirone, G., Tomassini, F., Vettoretto, N., and Zigiotto, D.

Subjects
Male, medicine.medical_specialty, Colorectal cancer, Settore MED/18 - CHIRURGIA GENERALE, Anastomotic Leak, 030230 surgery, Anastomosis, NO, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Medicine, Hepatectomy, Humans, Risk factor, Propensity Score, Colectomy, Aged, Retrospective Studies, Aged, 80 and over, business.industry, Incidence, Liver Neoplasms, Simultaneous resection, Cancer, General Medicine, Perioperative, Middle Aged, medicine.disease, Surgery, Settore MED/18, Oncology, Elective Surgical Procedures, 030220 oncology & carcinogenesis, Relative risk, Propensity score matching, Female, Synchronous colorectal liver metastasis, business, Colorectal Neoplasms
Abstract

Introduction how best to manage patients with colorectal cancer and synchronous liver metastasis is still controversial, with specific concerns of increased risk of postoperative complications following combined resection. We aimed at analyzing the influence of combined liver resection on the risk of anastomotic leak (AL) following colorectal resection. Methods we reviewed the iCral prospectively maintained database to compare the relative risk of AL of patients undergoing colorectal resection for cancer to that of patients receiving simultaneous liver and colorectal resection for cancer with isolated hepatic metastases. The incidence of AL was the primary outcome of the analysis. Perioperative details and postoperative complications were also appraised. Results out of a total of 996 patients who underwent colorectal resection for cancer, 206 receiving isolated colorectal resection were compared with a matched group of 53 patients undergoing simultaneous liver and colorectal resection. Combined surgery had greater operative time and resulted in longer postoperative hospitalization compared to colorectal resection alone. The proportion of overall morbidity following combined resection was significantly higher than after isolated colorectal resection (56.6% vs. 37.9%, p = 0.021). Overall, the two groups of patients did not differ neither on the rate of major postoperative complications, nor in terms of AL (9.4% vs. 6.3%, p = 0.381). At specific multivariate analysis, the duration of surgery was the only risk factor independently associated with the likelihood of AL. Conclusions combining hepatic with colorectal resection for the treatment of synchronous liver metastasis from colorectal cancer does not increase significantly the incidence of AL.

Published
2021

29. The role of resection for melanoma metastases to the pancreas

Author

Francesco Guerra, Diego Coletta, Gary B. Deutsch, Giuseppe Giuliani, Alberto Patriti, Trevan D. Fischer, Andrea Coratti, Simone Serafini, Rodrigo Surjan, Anna C. Milanetto, and Donata Campra

Subjects
Pancreatic Neoplasms, Survival Rate, Pancreatectomy, Hepatology, Gastroenterology, Humans, Middle Aged, Melanoma, Pancreas
Abstract

Among patients with distant metastatic melanoma, the site of metastases is the most significant predictor of survival and visceral-nonpulmonary metastases hold the highest risk of poor outcomes. However, studies demonstrate that a significant percentage of patients may be considered candidates for resection with improved survival over nonsurgical therapeutic modalities. We aimed at analyzing the results of resection in patients with melanoma metastasis to the pancreas by assessing the available evidence.The PubMed/MEDLINE, WoS, and Embase electronic databases were systematically searched for articles reporting on the surgical treatment of pancreatic metastases from melanoma. Relevant data from included studies were assessed and analyzed. Overall survival was the primary endpoint of interest. Surgical details and oncological outcomes were also appraised.A total of 109 patients treated surgically for pancreatic metastases were included across 72 articles and considered for data extraction. Overall, patients had a mean age of 51.8 years at diagnosis of pancreatic disease. The cumulative survival was 71%, 38%, and 26% at 1, 3 and 5 years after pancreatectomy, with an estimated median survival of 24 months. Incomplete resection and concomitant extrapancreatic metastasis were the only factors which significantly affected survival. Patients in whom the pancreas was the only metastatic site who received curative resection exhibited significantly longer survival, with a 1-year, 3-year, and 5-year survival rates of 76%, 43%, and 41%, respectively.Within the limitations of a review of non-randomized reports, curative surgical resection confers a survival benefit in carefully selected patients with pancreatic dissemination of melanoma.

Published
2022

31. Correction to: Ostomy closure rate during COVID-19 pandemic: an Italian multicentre observational study (Updates in Surgery, (2022), 74, 3, (1017-1025), 10.1007/s13304-022-01274-w)

Author

Balla, A., Saraceno, F., Di Saverio, S., Di Lorenzo, N., Lepiane, P., Guerrieri, M., Sileri, P., Agostinelli, L., Agresta, F., Anania, G., Antolino, L., Anoldo, P., Botteri, E., Bracale, U., Carbone, F., Carlini, M., Carrano, F. M., Casadei, G., Coletta, D., Crafa, F., De'Angelis, N., Delrio, P., De Palma, G. D., Di Martino, M., Elmore, U., Gozzini, L., Grieco, M., Levi Sandri, G. B., Licitra, E., Lucchi, A., Massani, M., Memeo, R., Milone, M., Oppici, D., Ortenzi, M., Patriti, A., Pecchini, F., Peltrini, R., Piccoli, M., Pisanu, A., Podda, M., Poggioli, G., Ranucci, M. C., Rega, D., Rosati, R., Roscio, F., Rottoli, M., Santoro, R., Sartori, A., Spinelli, A., Vanella, S., Vennarecci, G., and Vettoretto, N.

Published
2022

32. ERAS program adherence-institutionalization, major morbidity and anastomotic leakage after elective colorectal surgery: the iCral2 multicenter prospective study

Author

Marco, Catarci, Giacomo, Ruffo, Massimo, Giuseppe, Viola, Felice, Pirozzi, Paolo, Delrio, Felice, Borghi, Gianluca, Garulli, Gianandrea, Baldazzi, Pierluigi, Marini, Giuseppe, Sica, Gianluca, Guercioni, Paolo, Ciano, Michele, Benedetti, Simone, Cicconi, Irene, Marziali, Elisa, Bertocchi, Amedeo, Altamura, Francesco, Rubichi, Antonio, Sciuto, Ugo, Pace, Andrea Fares Bucci, Desirée, Cianflocca, Marco, Migliore, Basilio, Pirrera, Vincenzo, Alagna, Diletta, Cassini, Grazia Maria Attinà, Claudio, Arcudi, Bruno, Sensi, Roberto, Campagnacci, Angela, Maurizi, Massimo, Basti, Diletta, Frazzini, Valerio, Caracino, Corrado, Pedrazzani, Giulia, Turri, Stefano, Mancini, Andrea, Sagnotta, Marco, Scatizzi, Lorenzo, Pandolfini, Alessandro, Falsetto, Gian Luca Baiocchi, Sarah, Molfino, Mauro, Totis, Marco, Braga, Andrea, Liverani, Tatiana Di Cesare, Stefano, Scabini, Antonio, Martino, Raffaele De Luca, Michele, Simone, Alessandro, Carrara, Giuseppe, Tirone, Michele, Motter, Marco, Caricato, Gabriella Teresa Capolupo, Pietro, Amodio, Raffaele, Macarone, Palmieri, Maurizio, Pavanello, Carlo Di Marco, Andrea, Muratore, Patrizia, Marsanic, Alberto, Patriti, Valerio, Sisti, Andrea, Lucchi, Giacomo, Martorelli, Clementi, Marco, Guadagni, Stefano, Graziano, Longo, Federico, Tomassini, Simone, Santoni, Nereo, Vettoretto, Emanuele, Botteri, Andrea, Armellini, Giuseppe, Brisinda, Maria Michela Chiarello, Maria, Cariati, Stefano, Berti, Andrea, Gennai, Gabriele, Anania, Serena, Rubino, Walter, Siquini, Alessandro, Cardinali, Mariantonietta Di Cosmo, Daniele, Zigiotto, Lucio, Taglietti, Silvia, Ruggiero, Alberto Di Leo, Jacopo, Andreuccetti, Paolo, Millo, Manuela, Grivon, and Diana, Giannarelli.

Subjects
Male, medicine.medical_specialty, Anastomotic Leak, Anastomosis, Logistic regression, NO, Postoperative Complications, Colorectal surgery, Internal medicine, medicine, Anastomotic leakage, Humans, ERAS, Prospective Studies, Prospective cohort study, Univariate analysis, business.industry, Institutionalization, Odds ratio, Length of Stay, Colorectal surgery · ERAS · Major morbidity · Anastomotic leakage, Settore MED/18, Major morbidity, Surgery, Observational study, Morbidity, business, Enhanced Recovery After Surgery, Abdominal surgery
Abstract

Enhanced recovery after surgery (ERAS) programs influence morbidity rates and length of stay after colorectal surgery (CRS), and may also impact major complications and anastomotic leakage rates. A prospective multicenter observational study to investigate the interactions between ERAS program adherence and early outcomes after elective CRS was carried out. Prospective enrolment of patients submitted to elective CRS with anastomosis in 18 months. Adherence to 21 items of ERAS program was measured upon explicit criteria in every case. After univariate analysis, independent predictors of primary endpoints [major morbidity (MM) and anastomotic leakage (AL) rates] were identified through logistic regression analyses including all significant variables, presenting odds ratios (OR). Institutional ERAS protocol was declared by 27 out of 38 (71.0%) participating centers. Median overall adherence to ERAS program items was 71.4%. Among 3830 patients included in the study, MM and AL rates were 4.7% and 4.2%, respectively. MM rates were independently influenced by intra- and/or postoperative blood transfusions (OR 7.79, 95% CI 5.46–11.10; p

Published
2022

34. The impact of synchronous liver resection on the risk of anastomotic leakage following elective colorectal resection. A propensity score match analysis on behalf of the iCral study group

Author

Guerra, Francesco, primary, Petrelli, Filippo, additional, Greco, Paola Antonella, additional, Sisti, Valerio, additional, Catarci, Marco, additional, Montalti, Roberto, additional, Patriti, Alberto, additional, Alagna, V., additional, Amodio, P., additional, Anania, G., additional, Angeloni, R., additional, Arici, E., additional, Baiocchi, G., additional, Baraghini, M., additional, Benedetti, M., additional, Bertocchi, E., additional, Borghi, F., additional, Brisinda, G., additional, Campagnacci, R., additional, Capolupo, G.T., additional, Caricato, M., additional, Carrara, A., additional, Ceccaroni, M., additional, Chiarello, M.M., additional, Cianflocca, D., additional, Ciano, P., additional, Cicconi, S., additional, Clementi, M., additional, Delrio, P., additional, Di Cesare, T., additional, Di Marco, C., additional, Falsetto, A., additional, Garulli, G., additional, Guadagni, S., additional, Guercioni, G., additional, Lambertini, M., additional, Liverani, A., additional, Longo, G., additional, Lucchi, A., additional, Luzzi, A.P., additional, Macarone Palmieri, R., additional, Mancini, S., additional, Marini, P., additional, Marsanic, P., additional, Martino, A., additional, Martorelli, G., additional, Marziali, I., additional, Maurizi, A., additional, Migliore, M., additional, Molfino, S., additional, Motter, M., additional, Muratore, A., additional, Pace, U., additional, Pandolfini, L., additional, Pavanello, M., additional, Pirozzi, F., additional, Ruffo, G., additional, Ruggeri, B., additional, Sagnotta, A., additional, Santoni, S., additional, Scabini, S., additional, Scatizzi, M., additional, Sciuto, A., additional, Sica, G., additional, Tirone, G., additional, Tomassini, F., additional, Vettoretto, N., additional, and Zigiotto, D., additional

Published
2021
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37. Minimally Invasive Approach to Gastric GISTs: Analysis of a Multicenter Robotic and Laparoscopic Experience with Literature Review.

Author

Ceccarelli, Graziano, Costa, Gianluca, De Rosa, Michele, Codacci Pisanelli, Massimo, Frezza, Barbara, De Prizio, Marco, Bravi, Ilaria, Scacchi, Andrea, Gallo, Gaetano, Amato, Bruno, Bugiantella, Walter, Tacchi, Piergiorgio, Bartoli, Alberto, Patriti, Alberto, Cappuccio, Micaela, Komici, Klara, Mariani, Lorenzo, Avella, Pasquale, and Rocca, Aldo

Subjects
RESEARCH, ENDOSCOPIC surgery, SURGICAL robots, LAPAROSCOPIC surgery, MEDICAL cooperation, SURGERY, PATIENTS, GASTROINTESTINAL tumors, GASTRECTOMY, HEALTH care teams, DESCRIPTIVE statistics, CONNECTIVE tissue tumors
Abstract

Simple Summary: Gastrointestinal stromal tumors (GISTs) represent about 1–3% of all gastrointestinal malignancies, of which 50–60% are gastric GISTs (GGs). To the date, surgery represents the best therapeutic option, and the robotic gastric surgery could gain an important role, overcoming many laparoscopic drawbacks. The aim of this study is to evaluate safety and effectiveness of minimally invasive surgery (MIS) for GGs, reporting 10-year experience of three different centers. We included a population of 81 patients who underwent MIS approaches (36 laparoscopy vs. 45 robotic surgery). Seventy-two (72) patients were enrolled in a follow-up program to evaluate the long-term oncological outcomes. Furthermore, we discussed some technical notes and also we analyzed the operative and peri-operative outcomes. In conclusion, our results suggest that the robotic approach might be a suitable treatment, especially for GISTs >5 cm, even located in unfavorable places, despite longer operative time and costs than laparoscopic approach. Background: Gastrointestinal stromal tumors (GISTs) are most frequently located in the stomach. In the setting of a multidisciplinary approach, surgery represents the best therapeutic option, consisting mainly in a wedge gastric resection. (1) Materials and methods: Between January 2010 to September 2020, 105 patients with a primary gastrointestinal stromal tumor (GISTs) located in the stomach, underwent surgery at three surgical units. (2) Results: A multi-institutional analysis of minimally invasive series including 81 cases (36 laparoscopic and 45 robotic) from 3 referral centers was performed. Males were 35 (43.2%), the average age was 66.64 years old. ASA score ≥3 was 6 (13.3%) in the RS and 4 (11.1%) in the LS and the average tumor size was 4.4 cm. Most of the procedures were wedge resections (N = 76; 93.8%) and the main operative time was 151 min in the RS and 97 min in the LS. Conversion was necessary in five cases (6.2%). (3) Conclusions: Minimal invasive approaches for gastric GISTs performed in selected patients and experienced centers are safe. A robotic approach represents a useful option, especially for GISTs that are more than 5 cm, even located in unfavorable places. [ABSTRACT FROM AUTHOR]

Published
2021
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38. Abdominal drainage after elective colorectal surgery: propensity score-matched retrospective analysis of an Italian cohort.

Author

Guadagni S, Catarci M, Masedu F, Karim ME, Clementi M, Ruffo G, Viola MG, Borghi F, Baldazzi G, Scatizzi M, Pirozzi F, Delrio P, Garulli G, Marini P, Campagnacci R, De Luca R, Ficari F, Sica G, Scabini S, Liverani A, Caricato M, and Patriti A

Subjects
Humans, Retrospective Studies, Propensity Score, Drainage methods, Surgical Wound Infection epidemiology, Surgical Wound Infection prevention & control, Colorectal Surgery adverse effects
Abstract

Background: In Italy, surgeons continue to drain the abdominal cavity in more than 50 per cent of patients after colorectal resection. The aim of this study was to evaluate the impact of abdominal drain placement on early adverse events in patients undergoing elective colorectal surgery., Methods: A database was retrospectively analysed through a 1:1 propensity score-matching model including 21 covariates. The primary endpoint was the postoperative duration of stay, and the secondary endpoints were surgical site infections, infectious morbidity rate defined as surgical site infections plus pulmonary infections plus urinary infections, anastomotic leakage, overall morbidity rate, major morbidity rate, reoperation and mortality rates. The results of multiple logistic regression analyses were presented as odds ratios (OR) and 95 per cent c.i., Results: A total of 6157 patients were analysed to produce two well-balanced groups of 1802 patients: group (A), no abdominal drain(s) and group (B), abdominal drain(s). Group A versus group B showed a significantly lower risk of postoperative duration of stay >6 days (OR 0.60; 95 per cent c.i. 0.51-0.70; P < 0.001). A mean postoperative duration of stay difference of 0.86 days was detected between groups. No difference was recorded between the two groups for all the other endpoints., Conclusion: This study confirms that placement of abdominal drain(s) after elective colorectal surgery is associated with a non-clinically significant longer (0.86 days) postoperative duration of stay but has no impact on any other secondary outcomes, confirming that abdominal drains should not be used routinely in colorectal surgery., (© The Author(s) 2024. Published by Oxford University Press on behalf of BJS Society Ltd.)

Published
2024
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