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The analysis of toxic and essential elements in human matrices is used in clinical diagnostics and for biomonitoring of different populations to study related health outcomes. This work aimed to develop fast and reliable methods for the analysis of a broad range of elements in liquid human matrices, such as whole blood, serum, and urine, with a similar setup for the three matrices and different analysis needs. An easy and fast‐forward dilute‐and‐shoot method for 33 elements (i.e., Ag, Al, As, B, Ba, Be, Bi, Cd, Ce, Co, Cr, Cu, Hg, I, Li, Mn, Mo, Ni, Pb, Pd, Pt, Sb, Se, Sn, Sr, Te, Th, Tl, U, V, W, Zn, and Zr) was developed. 200 µL of either sample material was diluted with an alkaline reagent to a volume of 4 mL in total. Sample dilution and preparation of matrix‐matched calibration standards were performed in 48‐well plates by an automated liquid handler. Diluted samples were analyzed by inductively coupled plasma mass spectrometry on a Perkin Elmer NexIon 300D ICP‐MS instrument equipped with an ESI‐FAST SC2DX autosampler in kinetic energy discrimination mode with helium as cell gas at either 4.8 mL or 5.7 mL and 1600 W RF generator power. The method validation results showed good accuracy for fresh human samples from an external quality assessment scheme with measured concentrations within the assigned concentration ranges. Good precision and reproducibility for most elements were demonstrated with variation coefficients below or far below 8% and 15% for whole blood, 8% and 10% for serum, and 10% and 10% for urine, respectively. The developed reagent and instrumental setup were applicable to all three matrices. This minimizes the risk of human errors when switching between analyses of the different sample matrices and allows a rapid and easy analysis of whole blood, serum, and urine within one day if needed. The method demonstrated robustness over time, withstanding minor changes in the preparation of working solutions and samples, instrumental analysis, and setup. Analysis of human real samples showed the method's applicability for 33 toxic and essential elements in whole blood, serum, and urine and at concentrations relevant to clinical diagnostics as well as biomonitoring. [ABSTRACT FROM AUTHOR]

Zinc, a vital trace element, holds significant importance in numerous physiological processes within the body. It participates in over 300 enzymatic reactions, metabolic functions, regulation of gene expression, apoptosis and immune modulation, thereby demonstrating its essential role in maintaining overall health and well-being. While zinc deficiency is associated with significant health risks, an excess of this trace element can also lead to harmful effects. According to the World Health Organization (WHO), 6.7 to 15 mg per day are referred to be the dietary reference value. An excess of the recommended daily intake may result in symptoms such as anemia, neutropenia and zincinduced copper deficiency. The European Food Safety Authority (EFSA) defines the tolerable upper intake level (UL) as 25 mg per day, whereas the Food and Drug Administration (FDA) allows 40 mg per day. This review will summarize the current knowledge regarding the calculation of UL and other health risks associated with zinc. For example, zinc intake is not limited to oral consumption; other routes, such as inhalation or topical application, may also pose risks of zinc intoxication. [ABSTRACT FROM AUTHOR]

C19H23CuNO4, monoclinic, C2/c (no. 15), a = 16.1601(4) Å, b = 23.3298(7) Å, c = 12.8950(3) Å, β = 128.275(1)∘, V = 3816.6(2) Å3, Z = 8, Rgt(F) = 0.0620, wRref(F2) = 0.1251, T = 296(2) K. [ABSTRACT FROM AUTHOR]

Heavy metals (HMs) are ubiquitous in terrestrial and aquatic environments due to unplanned industrial waste discharge, the release of untreated wastewater, and improper mining activities. In particular, the concentrations of HMs are found to be higher in aquatic environments. As a result, the aquatic biota was heavily affected by HM contamination. This critical review aims to understand the sources and toxicity of HMs in commercial fish species, explore their ecological exchange, and examine the related human health challenges in Bangladesh. A modified PRISMA review technique is used in this paper to analyze the current status and research limitations of HM studies in Bangladesh fish species and their toxicity within aquatic food webs. Briefly, we searched several keywords to explore the research trend of HM concentrations and toxicity in fish species. Furthermore, potential toxicity and risk assessment of HMs through the aquatic food chain in Bangladesh were explored. On the other hand, a cross-tabulation approach was used to process the toxicity findings of HMs. Previous studies indicate that fish species can possess comparatively higher HMs than river water due to ecological exchange factors, including bioaccumulation and biotransformation. This review focuses on Bangladesh, highlighting areas for improvements and the need for further study to achieve a transparent understanding of HM deposition in fish species and the sustainable management of aquatic food chain toxicity., (© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)

In this era, where food safety and sustainability are paramount concerns, the utilization of zinc oxide (ZnO) nanoparticles (NPs) is a promising solution to enhance the safety, quality, and sustainability of food products. ZnO NPs in the food industry have evolved significantly over time, reflecting advancements in synthesizing methods, antimicrobial activities, and risk assessment considerations for human health and the environment. This comprehensive review delves into the historical trajectory, current applications, and prospects of ZnO NPs in food-related contexts. Synthesizing methods, ranging from solvothermal and solgel techniques to laser ablation and microfluidic reactors, have facilitated the production of ZnO NPs with tailored properties suited for diverse food applications. The remarkable antimicrobial activity of ZnO NPs against a wide spectrum of pathogens has garnered attention for their potential to enhance food safety and extend shelf-life. Furthermore, comprehensive risk assessment methodologies have been employed to evaluate the potential impacts of ZnO NPs on human health and the environment, regarding toxicity, migration, and ecological implications. By navigating the intricate interplay between synthesis methods, antimicrobial efficacy, inhibitory mechanisms, and risk assessment protocols, by elucidating the multifaceted role of ZnO NPs in shaping the past, present, and future of the food industry, this review offers valuable insights and promising avenues for researchers, policymakers, and industry stakeholders to enhance food safety, quality, and sustainability., (© 2024 The Author(s). Comprehensive Reviews in Food Science and Food Safety published by Wiley Periodicals LLC on behalf of Institute of Food Technologists.)

A fluoride-aided stabilization of manganese(III) was demonstrated by the preparation of unique complexes of the molecular mixed ligand fluoromanganate(III) from an aqueous medium. Complexes of mixed ligand fluoromanganate(III) were synthesized by reacting MnO(OH), 40% HF with nitrogen donor ligands that may function as neutral ligands, such as pyridine, ethylene diamine, or imidazole. The molecular complexes that were generated are stable and may be kept in polythene bags for extended periods of time without losing their properties. Consistency may be determined in a number of ways, including chemical analysis of the manganese oxidation state and periodic estimation of manganese and fluoride levels. The compounds dissolve slowly in water and partly in polar organic solvents. Element analyses, chemical oxidation state determination, FT-IR, electronic spectra, magnetic moment measurements at room temperature, thermogravimetric analysis (TGA/DTA), scanning electron microscopy (SEM), and cyclic voltammetry studies were used to characterize the complexes. The complexes produced probably have a distorted octahedral shape. [ABSTRACT FROM AUTHOR]

Cadmium (Cd) and arsenic (As) are both potentially toxic heavy metals (HMs) found ubiquitously in the environment. These HMs are prevalent in soil due to natural occurrences or anthropogenic activities. Co-contamination of Cd and As in soil is a major concern for plant and human health as well as ecosystem sustainability due to their hazardous properties. Therefore, a global imperative is developing improved technologies for managing and remediating soil co-contaminated with Cd and As. One effective solution for remediating Cd/As co-contaminated soil involves the utilization of natural biopolymers and biostimulants, such as chitosan (CS). CS offers distinct advantages, including its ready availability, biodegradability, biocompatibility, environmental friendliness, and cost-effectiveness when compared to alternative adsorbents. The adsorption mechanism of CS and CS-based adsorbents for Cd and As primarily relies on electrostatic attraction, complexation, and ion exchange. This review article provides a comprehensive overview of Cd and As co-contamination in soil, elucidating their sources, distribution patterns, exposure pathways, and the prospective remediation approaches employing CS biostimulants and CS-based adsorbents. Furthermore, it summarizes recent studies investigating the adsorption of Cd/As by CS, the factors influencing the adsorption efficiency and the challenges associated with the utilization of CS and CS-based adsorbents. In conclusion, the review underscores the need for further research to concurrently remediate Cd and As co-contaminated soil, enhance the adsorption efficiency of CS and CS-based composites, and broaden their practical applicability for remediating co-contaminated soils. [ABSTRACT FROM AUTHOR]

The dinuclear oxidovanadium(IV/V) complex, [V2(HS2O8)O3(C18H24N2)2]⋅- CH3CN or [V2O2(μ-O)( μ-H(SO4)2)(4,4'-tBubpy)2]⋅CH3CN (4,40-tBubpy = 4,4'-di-tert-butyl-2,2'-bipyridine), has crystallographic C2 symmetry and exhibits a distorted octahedral geometry around the vanadium center, where the two 4,4'-tBubpy ligands are nearly orthogonal to each other. The two vanadium ions are linked by an oxo anion and a unique protonated sulfate anion [H(SO4)23-]. In the crystal, intermolecular C--H⋯π and π--π interactions between the 4,4'-tBubpy ligands are present, leading to a three-dimensional network. [ABSTRACT FROM AUTHOR]

A mixed-ligand zinc(II) complex, [Zn(Hpma)(phen)Cl] (where Hpma- = N-(2,6-dimethylphenyl)oxamate and phen = 1,10-phenanthroline), has been prepared by the reaction of zinc chloride, ethyl (2,6-dimethylphenylcarbamoyl)formate (Hdmp) and 1,10-phenanthroline under basic conditions in dimethylformamide. The structure of the complex was characterised by elemental analysis, IR, 1H-NMR, UV-Vis absorption and X-ray crystallography. The metal complex crystallises in the monoclinic system (space group P21/c) and is composed of the five-coordinate zinc ion in a distorted spherical square pyramidal geometry. Stabilisation of single crystals occurs through hydrogen bonds and p-p stacking interactions. [ABSTRACT FROM AUTHOR]

Three new ligands viz, benzylacetone-benzoylhydrazone [babh (L)], para-hydroxy-benzylacetone-2 3 benzoylhydrazone [p-OH-babh (L)] and para-nitrobenzylacetone-benzoylhydrazone [p-NO -babh (L)], were 2 synthesised by condensation of hydrazides with benzylacetone. The ligands were each reacted with copper(II) - - salts (chloride, nitrate, acetate and sulphate) to form complexes with the general formulae ML X (X = Cl, NO, 2 2 3 - - 1 AcO and SO). The compounds were characterised using H NMR, Infrared and UV-Visible spectroscopy, as 4 well as CHN elemental analyser and magnetic susceptibility measurements. Antibacterial activity of the ligands and synthesised complexes were investigated using the agar diffusion method against two Gram-positive (Staphylococcus aureus NCTC 6571 and Bacillus cereus ATCC 11778) and three Gram-negative (Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 10145, Klebsiella pneumonia ATCC 13048) bacterial strains. However, the observed antimicrobial strength of the synthesized compounds was rather low. [ABSTRACT FROM AUTHOR]

Long non-coding RNAs (LncRNAs) play important regulatory roles in oxidative damage. Resveratrol, curcumin, and cyanidin are phytogenic antioxidants widely existing in nature and they have been proved to antagonize certain heavy metal-induced oxidative damage in cells. However, can they antagonize oxidative damage induced by cadmium in islet β cells? Are their mechanisms of antagonizing oxidative damage related to LncRNAs? In this study, we first detected the cell viability of each group by CCK8 assay. Next, reactive oxygen species (ROS) were detected by the fluorescent probe. The contents of malondialdehyde (MDA) and the activities of superoxide dismutase (SOD) were detected according to the instructions of corresponding kits. At last, the levels of LncRNAs were detected by fluorescence quantitative real-time polymerase chain reaction (qPCR). The results showed that resveratrol, curcumin and cyanidin were able to reverse the reduction of cell viability induced by cadmium (CdSO 4 ). Further determination revealed that SOD activities of the resveratrol+CdSO 4 , curcumin+CdSO 4 , and cyanidin+CdSO 4 treatment groups increased significantly, and ROS levels and MDA contents dramatically decreased when compared with single CdSO 4 -treated group. More importantly, the levels of three CdSO 4 -elevated LncRNAs (NONMMUT029382, ENSMUST00000162103, ENSMUST00000117235) were all decreased and levels of three CdSO 4 -inhibited LncRNAs (NONMMUT036805, NONMMUT014565, NONMMUT065427) were increased after the pretreatment of resveratrol, curcumin and cyanidin. In summary, resveratrol, curcumin and cyanidin may effectly reverse the cadmium-induced oxidative damage and suggest that phytogenic antioxidants may prevent cells from cadmium-induced oxidative damage through changing the levels of LncRNAs., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)

Comprehensive Summary: Metal clusters with photoswitching ligands can undergo magnetic changes under light radiation, which makes them potential optical‐response magnetic‐switching materials. Herein, a photoswitchable Mn‐oxo cluster [MnII15MnIII4(L)18(OH)12(N3)6] (ClO4)2 (C6H5CN)8, (Mn19azo, HL=1‐(hydroxymethyl)‐3,5‐dimethyl‐4‐(phenyldiazenyl)‐pyrazole) has been designed and synthesized to realize the photoswitching behavior. Mn19azo shows quick trans‐to‐cis transformation upon 365 nm light irradiation in CH2Cl2 solution and solid state as confirmed by UV‐Vis spectra. After the powder sample was irradiated for 80 min, the Curie constant of Mn19azo increases by about 7%. The change of magnetic properties can be considered as the result of the change of intermolecular interactions. [ABSTRACT FROM AUTHOR]

Phytopathogenic fungi secrete chitin deacetylase (CDA) to escape the host's immunological defense during infection. Here, we showed that the deacetylation activity of CDA toward chitin is essential for fungal virulence. Five crystal structures of two representative and phylogenetically distant phytopathogenic fungal CDAs, VdPDA1 from Verticillium dahliae and Pst_13661 from Puccinia striiformis f. sp. tritici, were obtained in ligand-free and inhibitor-bound forms. These structures suggested that both CDAs have an identical substrate-binding pocket and an Asp-His-His triad for coordinating a transition metal ion. Based on the structural identities, four compounds with a benzohydroxamic acid (BHA) moiety were obtained as phytopathogenic fungal CDA inhibitors. BHA exhibited high effectiveness in attenuating fungal diseases in wheat, soybean, and cotton. Our findings revealed that phytopathogenic fungal CDAs share common structural features, and provided BHA as a lead compound for the design of CDA inhibitors aimed at attenuating crop fungal diseases. Phytopathogenic fungi secrete chitin deacetylase (CDA) to escape the host's immunological defense during infection. Here, the authors reveal the common structural features of phytopathogenic fungal CDAs, and identify CDA inhibitors that are promising to control plant diseases. [ABSTRACT FROM AUTHOR]

Introduction. Parkinson's disease (PD) is the second most common neurological disorder. Patients with PD were affected by the COVID-19 pandemic in many different ways. This study's principal purpose is to assess PD patients' vulnerability to COVID-19 and its consequences. Method. This systematic review was performed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines. A thorough search was conducted in the Medline (through PubMed) and Scopus databases from inception to January 30, 2022. The Joanna Briggs Institute (JBI) critical appraisal checklist was used to evaluate the studies. Results. Most of the studies (38%) had been conducted in Italy. Of the total number of studies, 17 (58%) were cross-sectional, seven (22%) were cohort, four (12%) were quasiexperimental, two (6%) were case-control, and one (3%) was a qualitative study. The PD duration in patients ranged from 3.26 to 13.40 years (IQR1: 5.7 yrs., median: 3.688 yrs., and IQR3: 8.815 yrs.). Meanwhile, the sample size ranged from 12 to 30872 participants (IQR1: 46, median: 96, and IQR3: 211). Despite worsening PD symptoms in the targeted population (persons with COVID-19 and Parkinson's disease), some studies found PD to be a risk factor for more severe COVID-19 disease. There are many adverse effects during the pandemic period in PD patients such as abnormalities of motor, nonmotor functioning, clinical outcomes, activities of daily living, and other outcomes. Conclusion. This study confirmed the negative effect of the COVID-19 pandemic on health-related quality of life and its determinants in patients with PD and their caregivers. Thus, due to the worsening symptoms of PD patients in the current pandemic, these people should be given more care and supervision to minimize their coronavirus exposure. [ABSTRACT FROM AUTHOR]

Cadmium is a heavy metal, dangerous environmental pollutant that negatively affects the body and the functioning of its organs and systems: blood, heart, liver, kidneys, and nervous system. It also harms the immune system, reducing the body's resistance to infections and increasing the risk of developing allergic, autoimmune, and oncological diseases. We studied the indicators of the humoral and nonspecific links of the immune system in young cattle subject to cadmium loading and the effects of a feed supplement and a liposomal preparation. The animals were divided into three groups of 5 each. Cadmium loading was attained by feeding cadmium chloride with feed in the dose of 0.04 mg/kg of the animal's body weight. The animals of the experimental groups were additionally given Metisevit and Butaselmevit. Usage of these drugs was accompanied by strengthening of the immune status of the body of young cattle, including increased bactericidal and lysozyme activities of blood serum, increased phagocytic activity, and phagocytic index, simultaneously with decrease in the level of circulating immune complexes in blood. In the conditions of experimental cadmium loading, we observed the best results in strengthening of the immune defense of the animals after combined use of the Metisevit feed additive and the Butaselmevit liposomal drug. These changes in the body of young cattle were associated with the complex effect of the components of the feed supplement and the liposomal preparation. The advantages of the liposomal form of Butaselmevit were more pronounced and longer-lasting effects. The Metisevit supplement and Butaselmevit liposomal drug were observed to be highly effective when used together during cadmium loading. [ABSTRACT FROM AUTHOR]

To determine that p38 MAPK activation contributes to the migration and invasion of lung cancer cells caused by cadmium (Cd). A549 lung cancer cell migration and invasion were assessed using a transwell plate system, and the role of p38 was determined by knocking down p38 activity with two different inhibitors of p38. The activity of p38 was measured by western blot analysis using phospho-specific p38 antibodies and normalized to blots using antibodies directed to total p38 proteins. Snail transcripts were measured using qRT-PCR. The inhibition of p38 blocked Cd-induced migration and invasion, which correlated with an increased activation of p38 as a function of dose and time. Furthermore, Cd-induced activation of p38 MAPK controlled the increase of snail mRNA expression. The p38 MAPK/snail signaling axis was involved in Cd-induced lung cancer cell migration and invasion., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

By annealing an Fe(III)â€"coordination compound (Feâ€"CC), [FeCl3(Hbta)2] (Hbta = benzotriazole) in the presence of a carbon nanotube precursor (PCNT) template, an Fe4N/Fe3N/Fe/CNT heterostructure was successfully synthesized without an extra nitrogen source. The decomposition of the Hbta in Feâ€"CC under high-temperature annealing can produce carbon sheets and reduced graphene oxide (rGO), and the presence of CNTs can alleviate the stacking of the in situ- generated carbon materials. Meanwhile, iron nitride nanoparticles (NPs) can be anchored on the carbon sheets, and the anchoring effect efficiently prevents the agglomeration of NPs and increases the amount of active catalytic sites for the oxygen evolution reaction (OER). Fe4N/Fe3N/Fe/CNT shows an excellent OER activity with a Tafel slope of 63 mV decâˆ'1 as well as overpotentials of 121 (η 10) and 275 mV (η 100) at 10 and 100 mA cmâˆ'2, respectively â€" far exceeding commercial RuO2 and other catalysts. Density functional theory calculations show that the excellent OER performance of Fe4N/Fe3N/Fe/CNT is associated with the Fe4N/Fe3N heterojunction, which can improve the electron conductivity and boost the electron transfer from N to Fe. The Fe4N/Fe3N/Fe/CNT catalyst exhibits long-term OER activity during 100 h of electrolysis at 20 mA cmâˆ'2. This is related to the dual coatings of the in situ- generated thin carbon shell and few-layered rGO on the surface of the iron nitride NPs, which can protect the fast leaching of iron nitride during the OER process. Furthermore, the effects of the annealing temperature, the PCNT template and the heating rate on the calcined products were investigated. [ABSTRACT FROM AUTHOR]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan, China in December 2019 and caused a global pandemic resulting in millions of deaths and tens of millions of patients positive tests. While studies have shown a D614G mutation in the viral spike protein are more transmissible, the effects of this and other mutations on the host response, especially at the cellular level, are yet to be fully elucidated. In this experiment we infected normal human bronchial epithelial (NHBE) cells with the Washington (D614) strain or the New York (G614) strains of SARS-CoV-2. We generated RNA sequencing data at 6, 12, and 24 hours post-infection (hpi) to improve our understanding of how the intracellular host response differs between infections with these two strains. We analyzed these data with a bioinformatics pipeline that identifies differentially expressed genes (DEGs), enriched Gene Ontology (GO) terms and dysregulated signaling pathways. We detected over 2,000 DEGs, over 600 GO terms, and 29 affected pathways between the two infections. Many of these entities play a role in immune signaling and response. A comparison between strains and time points showed a higher similarity between matched time points than across different time points with the same strain in DEGs and affected pathways, but found more similarity between strains across different time points when looking at GO terms. A comparison of the affected pathways showed that the 24hpi samples of the New York strain were more similar to the 12hpi samples of the Washington strain, with a large number of pathways related to translation being inhibited in both strains. These results suggest that the various mutations contained in the genome of these two viral isolates may cause distinct effects on the host transcriptional response in infected host cells, especially relating to how quickly translation is dysregulated after infection. This comparison of the intracellular host response to infection with these two SARS-CoV-2 isolates suggest that some of the mechanisms associated with more severe disease from these viruses could include virus replication, metal ion usage, host translation shutoff, host transcript stability, and immune inhibition. [ABSTRACT FROM AUTHOR]

The use of 2-pyridyl oximes in metal complexes chemistry has been extensively investigated in the last few decades as a fruitful source of species with interesting magnetic properties. In this work, the initial combination of pyridine-2-amidoxime (pyaoxH2) and 2-methyl pyridyl ketoxime (mpkoH) with isonicotinic acid (HINA) and 3,5-pyrazole dicarboxylic acid (H3pdc) has provided access to three new compounds, [Ni4(INA)2(pyaox)2(pyaoxH)2(DMF)2] (1), [Co5(mpko)6(mpkoH)2(OMe)2(H2O)](ClO4)6 (2), and [Co5(OH)(Hpdc)5(H2pdc)] (3). 1 displays a square-planar metal topology, being the first example that bears simultaneously HINA and pyaoxH2 in their neutral or ionic form. The neighbouring Ni4 units in 1 are held together through strong intermolecular hydrogen bonding interactions, forming a three-dimensional supramolecular framework. 2 and 3 are mixed-valent Co4IIICoII and Co2IIICoII3 compounds with a bowtie and trigonal bipyramidal metal topology, accordingly. Direct current and alternate current magnetic susceptibility studies revealed that the exchange interactions between the NiII ions in 1 are ferromagnetic (J = 1.79(4) cm−1), while 2 exhibits weak AC signals in the presence of a magnetic field. The syntheses, crystal structures, and magnetic properties of 1–3 are discussed in detail. [ABSTRACT FROM AUTHOR]

Microwave-assisted synthesis is considered environmental-friendly and, therefore, in agreement with the principles of green chemistry. This form of energy has been employed extensively and successfully in organic synthesis also in the case of metal-catalyzed synthetic procedures. However, it has been less widely exploited in the synthesis of metal complexes. As microwave irradiation has been proving its utility as both a time-saving procedure and an alternative way to carry on tricky transformations, its use can help inorganic chemists, too. This review focuses on the use of microwave irradiation in the preparation of transition metal complexes and organometallic compounds and also includes new, unpublished results. The syntheses of the compounds are described following the group of the periodic table to which the contained metal belongs. A general overview of the results from over 150 papers points out that microwaves can be a useful synthetic tool for inorganic chemists, reducing dramatically the reaction times with respect to traditional heating. This is often accompanied by a more limited risk of decomposition of reagents or products by an increase in yield, purity, and (sometimes) selectivity. In any case, thermal control is operative, whereas nonthermal or specific microwave effects seem to be absent. [ABSTRACT FROM AUTHOR]

Copper(II) complexes with nicotinamide and nicotinate ion are synthesized. The composition and structure of the complexes are determined via elemental analysis and IR spectroscopy. Products of the thermal decomposition of the complexes are studied experimentally via synchronous thermal gravimetric and IR analysis. Changes in the enthalpy of Cu2+ complexation with nicotinate ions in a water–ethanol binary solvent are determined, and the obtained data are analyzed in terms of the solvation thermodynamic approach. It is found that differences in the enthalpy characteristics of solvation of the central and complex ions neutralize the contribution from ligand desolvation, resulting in small changes to the ΔtrHr value. [ABSTRACT FROM AUTHOR]

The article offers information on single molecule magnet (SMM) which are described in the literature, mononuclear complexes, also known as single-ion magnets (SIMs)2-4 and polynuclear complexes, which can be either homo-5-7 or heterometallic. It discusses that Single crystal X-ray diffraction studies revealed the expected, L3 M3 Ln structural motif and structure was present for all complexes discussed.

The article highlights a study of salicylaldoxime based iron clusters has been fuelled by the presence of analogous Fe3 O triads observed in biologically important metalloproteins4 and also as analogues of magnetically interesting manganese complexes. It discusses that Salicylaldoximes and derivatised salicylaldoximes are well known to form multinuclear species, often featuring three-fold symmetric triangular metal rings.

The solid-state structure of the cobalt-β-picoline-sulfate complex tetra-μ3-sulfato-tetrakis[bis(3-methylpyridine)cobalt(II)], [CO4(SO4)4(C6H7N)8], is reported. The tetrameric cobalt cluster contains a cuboidal core comprised of four cobalt(II) cations and four sulfate anions at alternate cube vertices. The cobalt corners are each capped with two β-picoline ligands. The sulfate anions adopt a rare [3.2110] bridging motif, and the cuboidal cluster is unprecedented in coordination chemistry. [ABSTRACT FROM AUTHOR]

In this work, an N4-donor Schiff base ligand, N,N'-(propane-1,2-diyl)bis(1-phenyl-1-(pyridin-2-yl)methanimine) (PPPM) and its Mn(II) complex, [Mn(PPPM)(OAc)2]·3H2O (1), were prepared and identified by elemental analysis, FT-IR, 1H NMR spectroscopy as well single-crystal X-ray diffraction. X-ray structure analysis of 1 revealed a distorted square-face bicapped trigonal prism geometry around manganese atom with MnN4O4 environment containing an N4-donor PPPM and two O2-donor acetato ligands. The ligand has a chiral center on carbon atom which leads to the formation of a racemic mixture of complex 1. In the crystal structure of complex, intermolecular hydrogen bonds form R44(8) hydrogen bond motifs. The ability of two optical isomers of PPPM ligand and manganese complex to interact with 10 selected biomacromolecules (BRAF kinase, CatB, DNA gyrase, HDAC7, rHA, RNR, TrxR, TS, Top II, B-DNA) was investigated by docking studies. These studies revealed that PPPMR,S and 1R,S isomers can bind to these molecules better than doxorubicin (except B-DNA). [ABSTRACT FROM AUTHOR]

Ranipet is an industrial hub located 120 km away from Chennai houses around 250 tanneries beside other industries. Tanneries and Tamil Nadu Chromate and Chemicals Limited (TCCL) generated and dumped tons of chromium waste on land and water bodies which is the major threat to the people living in the area for several years. In this study, heavy metal pollution in Ranipet industrial zone was estimated using the Heavy Metal Pollution Index (HPI) model along with spatial distribution maps. The level of Cd, Cu, Cr, Pb, Ni and Zn in ground and surface water was measured using standard methods, and the results were utilized to make the HPI model. It was observed that the metal level was in the order of Zn > Pb > Ni > Cu > Cr > Cd and Cr > Pb > Zn > Cd > Cu > Ni in ground and surface water respectively. All the ground water samples exhibited high HPI of (> 38). Except one sample with low HPI (˂ 19), and three surface water samples held in midrange (19-38), the other surface water samples displayed high HPI of (> 38). The average HPI of ground and surface water is 500.42 and 523.78. The HPI and spatial distribution of heavy metals revealed that the Cr contamination in Ranipet industrial estate is originated from the premises of TCCL., (© 2023. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)

C14H12N6O6Mn, monoclinic, P21/n (no. 14), a = 7.0839(3) Å, b = 13.1211(4) Å, c = 8.9854(3) Å, β = 112.359(5)∘, V = 772.39(5) Å3, Z = 2, Rgt(F) = 0.0274, wRref(F2) = 0.0725, T = 293 K. [ABSTRACT FROM AUTHOR]