Search

Temporary blindness, also known as transient cortical blindness, is an uncommon impediment of contrast agent usage during angiography procedures. The occurrence of blindness after a cardiac catheterization procedure is rare and its pathophysiology remains largely speculative. The most probable mechanism seems to be contrast agent-related disruption of the blood–brain barrier, possibly initiated by several predisposing factors. This case reports a 52-year-old man with transient vision loss that occurred following coronary angiography. Brain magnetic resonance imaging (MRI) showed no acute pathology and his vision spontaneously returned within approximately 15 hours post-procedure without any requirement of specific therapy. Suggesting that transient cortical blindness may have occurred following coronary angiography which subsequently self-resolved.

Aim To evaluate the antibacterial effect of Khadirarishta (An Ayurvedic traditional formulation) against some of the bacterial strains as well as to investigate the probable mechanism of action against sensitive bacterial strains by using standard procedures. Methods The antibacterial activity of Khadirarishta against some of the bacterial strains was evaluated by using bacterial susceptibility assay and the broth Microdilution method by using microplate reader and p-iodonitrotetrazolium chloride (INT) reagent assay. The mechanism of action of Khadirarishta was observed by its effects on the bacterial membrane followed by quantification of effluxes components. Resistance analysis and Combination effect of Khadirarishta was also performed to explore its antibacterial dimensions. HPLC analysis of Khadirarishta was carried out for identifying the different marker compounds. Results Khadirarishta revealed a significant (p Conclusion This study shows that Khadirarishta has antibacterial potency and has a vigorous effect on the bacterial cell wall and membrane permeability. This could be due to the presence of identified marker compounds in this herb-decoction based Ayurvedic traditional formulation.