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Background: In modern radiotherapy techniques, the frequently small and non-uniformed fields can increase treatment efficiency due to their highly conformal dose distribution. Particular features including lack of Lateral Charge Particle Equilibrium (LCPE) lead to detectors with high resolution since any error in obtained dosimetric data could cause patient mistreatments.Objective: This study aims to evaluate and compare two small detectors (Semiflex®3D and microdiamond) dosimetric characteristics in small field relative dosimetry.Material and Methods: In this experimental study, the dosimetric properties of Semiflex®3D and microdiamond were assessed under 6 and 15 MV photon beams. The linearity and stability of the detector’s response and dose rate were measured. Square-field sizes ranging from 0.6×0.6 - 5×5 cm2 were used for obtaining percentage depth dose curves (PDDs) and in-plane profiles. The angular and temperature dependence of both detectors’ responses were also studied.Results: The detector response shows good stability, no deviation from linearity, and low dose rate dependence (≤1.6%). PDDs and in-plan profiles of both detectors are in good agreement and no significant difference was observed except for the high dose gradient regions (P-value≤0.017). Both detectors demonstrated low angular dependence (

Objective. We demonstrate detection of high energy particle current (HEC) for MeV therapeutic electron beams. Detection of HEC comprises of remote sensing or acquiring information about HEC inside radiation transport medium from a distance outside of the medium. Approach. HEC is self-propelled motion of charged particles through a radiation transport medium. Remote sensing of HEC is embodied in an experimental setup, which includes homogeneous and heterogeneous phantoms irradiated with 4-15 MeV electron beams and two large area parallel-plane electrodes extraneous to the phantoms providing two-parameter detection. We also introduce a new type of scanning method (depth-scan) for probing object properties along the beamline axis. Main Results. Deterministic radiation transport simulations and measurements agree, considering differences in simulation vs experimental geometry and experimental uncertainties. Significance. This method may be suitable for range detection of charged particle beams, or for probing of radiation opaque objects in non-destructive testing., (© 2024 Institute of Physics and Engineering in Medicine. All rights, including for text and data mining, AI training, and similar technologies, are reserved.)

Objective . Very high energy electrons (VHEE) in the range of 50-250 MeV are of interest for treating deep-seated tumours with FLASH radiotherapy (RT). This approach offers favourable dose distributions and the ability to deliver ultra-high dose rates (UHDR) efficiently. To make VHEE-based FLASH treatment clinically viable, a novel beam monitoring technology is explored as an alternative to transmission ionisation monitor chambers, which have non-linear responses at UHDR. This study introduces the fibre optic flash monitor (FOFM), which consists of an array of silica optical fibre-based Cherenkov sensors with a photodetector for signal readout. Approach . Experiments were conducted at the CLEAR facility at CERN using 200 MeV and 160 MeV electrons to assess the FOFM's response linearity to UHDR (characterised with radiochromic films) required for FLASH radiotherapy. Beam profile measurements made on the FOFM were compared to those using radiochromic film and scintillating yttrium aluminium garnet (YAG) screens. Main results . A range of photodetectors were evaluated, with a complementary-metal-oxide-semiconductor (CMOS) camera being the most suitable choice for this monitor. The FOFM demonstrated excellent response linearity from 0.9 Gy/pulse to 57.4 Gy/pulse ( R 2 = 0.999). Furthermore, it did not exhibit any significant dependence on the energy between 160 MeV and 200 MeV nor the instantaneous dose rate. Gaussian fits applied to vertical beam profile measurements indicated that the FOFM could accurately provide pulse-by-pulse beam size measurements, agreeing within the error range of radiochromic film and YAG screen measurements, respectively. Significance . The FOFM proves to be a promising solution for real-time beam profile and dose monitoring for UHDR VHEE beams, with a linear response in the UHDR regime. Additionally it can perform pulse-by-pulse beam size measurements, a feature currently lacking in transmission ionisation monitor chambers, which may become crucial for implementing FLASH radiotherapy and its associated quality assurance requirements., (Creative Commons Attribution license.)

Ultra-short electron beams are used as ultra-fast radiation source for radiobiology experiments aiming at very high energy electron beams (VHEE) radiotherapy with very high dose rates. Laser plasma accelerators are capable of producing electron beams as short as 1 fs and with tunable energy from few MeV up to multi-GeV with compact footprint. This makes them an attractive source for applications in different fields, where the ultra-short (fs) duration plays an important role. The time dynamics of the dose deposited by electron beams with energies in the range 50-250 MeV have been studied and the results are presented here. The results set a quantitative limit to the maximum dose rate at which the electron beams can impart dose., (Creative Commons Attribution license.)

The SSRMP recommendations on reference dosimetry in kilovolt beams as used in radiation therapy were revised to establish current practice in Switzerland. The recommendations specify the dosimetry formalism, reference class dosimeter systems and conditions used for the calibration of low and medium energy x-ray beams. Practical guidance is provided on the determination of the beam quality specifier and all corrections required for converting instrument readings to absorbed dose to water. Guidance is also provided on the determination of relative dose under non-reference conditions and on the cross calibration of instruments. The effect of lack of electron equilibrium and influence of contaminant electrons when using thin window plane parallel chambers at x-ray tube potentials higher than 50kV is elaborated in an appendix. In Switzerland the calibration of the reference system used for dosimetry is regulated by law. METAS and IRA are the authorities providing this calibration service to the radiotherapy departments. The last appendix of these recommendations summarise this calibration chain., Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 The Author(s). Published by Elsevier GmbH.. All rights reserved.)

Response of personal dosemeters to high energy photon radiation is of great interest nowadays due to a spread of new radiation technologies and the expansion of occupational exposure domains. ICRU95 publication has expanded the range of relevant photon energies upwards, setting new horizons for individual monitoring. Beryllium oxide (BeO) material is increasingly popular due to its excellent optically stimulated luminescence (OSL) properties, simple readout and reasonable energy response in the low energy (below 100 keV) range. The study considers energy dependence of OSL response at higher photon energies. Energy deposition of monoenergetic photons with energy up to 15 MeV in the BeO chips of various thickness was modeled with Monte Carlo MCNP 6.2 code. Benchmark experiments were conducted at LINAC with high voltage of 6, 10 and 15 MV resulting in respective incident photon spectra. The findings of this study add knowledge regarding behavior of BeO personal dosemeters in the photon fields within the energy range above 3 MeV., (© The Author(s) 2023. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)

Treatment of cancer is carried out using photon beams from high-energy medical linear accelerators. Photo-neutrons are also produced as an unwanted by product in the process of dose delivery to the cancer patients during their radiation treatments. In the present study, photo-neutron dose equivalents (both thermal and fast components) per unit delivered gamma-photon dose were measured at different depths, as function of distances from iso-centre in patient plane, field sizes, wedge angles and at LINAC head for a 15-MV medical linear accelerator model Elekta Precise using multi-foil activation technique. The neutron dose equivalents determined for the above-mentioned parameters were found to be lower (<0.05%) in comparison with the therapeutic photon dose delivered and within the prescribed limits recommended by the national regulatory authority., (© The Author(s) 2023. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)

Background: In modern radiotherapy techniques, the frequently small and non-uniformed fields can increase treatment efficiency due to their highly conformal dose distribution. Particular features including lack of Lateral Charge Particle Equilibrium (LCPE) lead to detectors with high resolution since any error in obtained dosimetric data could cause patient mistreatments., Objective: This study aims to evaluate and compare two small detectors (Semiflex ® 3D and microdiamond) dosimetric characteristics in small field relative dosimetry., Material and Methods: In this experimental study, the dosimetric properties of Semiflex ® 3D and microdiamond were assessed under 6 and 15 MV photon beams. The linearity and stability of the detector's response and dose rate were measured. Square-field sizes ranging from 0.6×0.6 - 5×5 cm 2 were used for obtaining percentage depth dose curves (PDDs) and in-plane profiles. The angular and temperature dependence of both detectors' responses were also studied., Results: The detector response shows good stability, no deviation from linearity, and low dose rate dependence (≤1.6%). PDDs and in-plan profiles of both detectors are in good agreement and no significant difference was observed except for the high dose gradient regions ( P -value≤0.017). Both detectors demonstrated low angular dependence (<0.3%) with temperature dependence lower than 1% for both detectors., Conclusion: The results indicate both investigated detectors were well performed in small field relative dosimetry and for measuring penumbra, it is better to use microdiamond detector., Competing Interests: None, (Copyright: © Journal of Biomedical Physics and Engineering.)