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16 results on '"Rana, Zaker"'

4. WNT Pathway Mutations in Metachronous Oligometastatic Castration-Sensitive Prostate Cancer

Author

Sutera, Philip, Deek, Matthew P., Van der Eecken, Kim, Shetty, Amol C., Chang, Jin Hee, Hodges, Theresa, Song, Yang, Verbeke, Sofie, Van Dorpe, Jo, Fonteyne, Valérie, De Laere, Bram, Mishra, Mark, Rana, Zaker, Molitoris, Jason, Ferris, Matthew, Ross, Ashley, Schaeffer, Edward, Roberts, Nicholas, Song, Daniel Y., DeWeese, Theodore, Pienta, Kenneth J., Antonarakis, Emmanuel S., Ost, Piet, and Tran, Phuoc T.

Published
2023
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6. Identification of a Predictive Genomic Biomarker for Prostate-directed Therapy in Synchronous Low-volume Metastatic Castration-sensitive Prostate Cancer

Author

Sutera, Philip, primary, Shetty, Amol C., additional, Song, Yang, additional, Hodges, Theresa, additional, Hoang, Tung, additional, Rana, Zaker, additional, Pienta, Kenneth, additional, Feng, Felix, additional, Song, Daniel Y., additional, DeWeese, Theodore, additional, Gillessen, Silke, additional, Sweeney, Christopher, additional, James, Nicholas, additional, Attard, Gerhardt, additional, Deek, Matthew, additional, and Tran, Phuoc T., additional

Published
2023
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7. Clinical and Genomic Differences Between Advanced Molecular Imaging-detected and Conventional Imaging-detected Metachronous Oligometastatic Castration-sensitive Prostate Cancer

Author

Sutera, Philip, primary, Song, Yang, additional, Van der Eecken, Kim, additional, Shetty, Amol C., additional, English, Keara, additional, Hodges, Theresa, additional, Chang, Jinhee, additional, Fonteyne, Valérie, additional, Rana, Zaker, additional, Ren, Lei, additional, Mendes, Adrianna A., additional, Lumen, Nicolaas, additional, Delrue, Louke, additional, Verbeke, Sofie, additional, De Man, Kathia, additional, Song, Daniel Y., additional, Pienta, Kenneth, additional, Feng, Felix Y., additional, Joniau, Steven, additional, Lotan, Tamara, additional, Lane, Barton, additional, Kiess, Ana, additional, Rowe, Steven, additional, Pomper, Martin, additional, DeWeese, Theodore, additional, Deek, Matthew, additional, Sweeney, Christopher, additional, Ost, Piet, additional, and Tran, Phuoc T., additional

Published
2023
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8. Prognostic impact of circulating tumor cells in oligometastatic hormone-sensitive prostate cancer following metastasis-directed therapy.

Author

Bazyar, Soha, primary, Sutera, Philip, additional, Phillips, Ryan, additional, Deek, Mathew Pierre, additional, Radwan, Noura, additional, Marshall, Catherine Handy, additional, Mishra, Mark V., additional, Rana, Zaker Hamid, additional, Molitoris, Jason K., additional, Kwok, Young, additional, Gupta, Santosh, additional, Tubbs, Alisa, additional, Wenstrup, Rick, additional, DeWeese, Theodore L., additional, Song, Daniel Y., additional, Feng, Felix Y, additional, Pienta, Kenneth J., additional, Antonarakis, Emmanuel S., additional, Kiess, Ana Ponce, additional, and Tran, Phuoc T., additional

Published
2023
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9. Genomic determinants of patterns of failure in metachronous oligometastatic castration-sensitive prostate cancer.

Author

Sutera, Philip, primary, Van der Eecken, Kim, additional, Shetty, Amol, additional, Song, Yang, additional, Hodges, Theresa, additional, Verbeke, Sofie, additional, Van Dorpe, Jo, additional, Fonteyne, Valerie, additional, De Laere, Bram, additional, Mishra, Mark V., additional, Rana, Zaker Hamid, additional, Molitoris, Jason K., additional, Ferris, Matthew J., additional, Roberts, Nicholas J, additional, Song, Daniel Y., additional, DeWeese, Theodore L., additional, Pienta, Kenneth J., additional, Deek, Matthew, additional, Ost, Piet, additional, and Tran, Phuoc T., additional

Published
2023
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10. Phase 2 randomized total eradication of metastatic lesions following definitive radiation to the prostate in de novo oligometastatic prostate cancer (TERPs) trial.

Author

Rana, Zaker Hamid, primary, Helie, Nicole, additional, Eggleston, Caitlin, additional, Baker, Kaysee, additional, Molitoris, Jason K., additional, Ferris, Matthew J., additional, Patel, Akshar, additional, Kwok, Young, additional, McAvoy, Sarah, additional, Kunaprayoon, Dan, additional, Hong, Jack J., additional, Deek, Matthew, additional, Sutera, Philip, additional, Deek, Rebecca A, additional, Bentzen, Soren, additional, Siddiqui, Minhaj, additional, Mannuel, Heather Dorothy, additional, Hussain, Arif, additional, Tran, Phuoc T., additional, and Mishra, Mark V., additional

Published
2023
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12. Long-Term Outcomes and Genetic Predictors of Response to Metastasis-Directed Therapy Versus Observation in Oligometastatic Prostate Cancer: Analysis of STOMP and ORIOLE Trials

Author

Deek, Matthew P., primary, Van der Eecken, Kim, additional, Sutera, Philip, additional, Deek, Rebecca A., additional, Fonteyne, Valérie, additional, Mendes, Adrianna A., additional, Decaestecker, Karel, additional, Kiess, Ana Ponce, additional, Lumen, Nicolaas, additional, Phillips, Ryan, additional, De Bruycker, Aurélie, additional, Mishra, Mark, additional, Rana, Zaker, additional, Molitoris, Jason, additional, Lambert, Bieke, additional, Delrue, Louke, additional, Wang, Hailun, additional, Lowe, Kathryn, additional, Verbeke, Sofie, additional, Van Dorpe, Jo, additional, Bultijnck, Renée, additional, Villeirs, Geert, additional, De Man, Kathia, additional, Ameye, Filip, additional, Song, Daniel Y., additional, DeWeese, Theodore, additional, Paller, Channing J., additional, Feng, Felix Y., additional, Wyatt, Alexander, additional, Pienta, Kenneth J., additional, Diehn, Maximillian, additional, Bentzen, Soren M., additional, Joniau, Steven, additional, Vanhaverbeke, Friedl, additional, De Meerleer, Gert, additional, Antonarakis, Emmanuel S., additional, Lotan, Tamara L., additional, Berlin, Alejandro, additional, Siva, Shankar, additional, Ost, Piet, additional, and Tran, Phuoc T., additional

Published
2022
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13. Genomic biomarkers to guide precision radiotherapy in prostate cancer

Author

Sutera, Philip, primary, Deek, Matthew P., additional, Van der Eecken, Kim, additional, Wyatt, Alexander W., additional, Kishan, Amar U., additional, Molitoris, Jason K., additional, Ferris, Matthew J., additional, Siddiqui, M. Minhaj, additional, Rana, Zaker, additional, Mishra, Mark V., additional, Kwok, Young, additional, Davicioni, Elai, additional, Spratt, Daniel E., additional, Ost, Piet, additional, Feng, Felix Y., additional, and Tran, Phuoc T., additional

Published
2022
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14. Genomic Determinants Associated with Modes of Progression and Patterns of Failure in Metachronous Oligometastatic Castration-sensitive Prostate Cancer

Author

Sutera, Philip, Song, Yang, Shetty, Amol C., English, Keara, Van der Eecken, Kim, Guler, Ozan Cem, Wang, Jarey, Cao, Yufeng, Bazyar, Soha, Verbeke, Sofie, Van Dorpe, Jo, Fonteyne, Valérie, De Laere, Bram, Mishra, Mark, Rana, Zaker, Molitoris, Jason, Ferris, Matthew, Kiess, Ana, Song, Daniel Y., DeWeese, Theodore, Pienta, Kenneth J., Barbieri, Christopher, Marchionni, Luigi, Ren, Lei, Sawant, Amit, Simone, Nicole, Berlin, Alejandro, Onal, Cem, Tran, Phuoc T., Ost, Piet, and Deek, Matthew P.

Abstract

For patients with metachronous oligometastatic castration-sensitive prostate cancer, tumor genomics may play a role in the mode of progression and pattern of failure after initial therapy for metastatic disease. Specifically, patients with TP53and RB1mutations have a higher likelihood of progression, and TP53, SPOP, and WNT pathway mutations may have a role in metastatic organotropism directing the likelihood of bone and visceral disease progression.

Published
2024
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15. Prognostic Significance of Immune Cell Infiltration in Muscle-invasive Bladder Cancer Treated with Definitive Chemoradiation: A Secondary Analysis of RTOG 0524 and RTOG 0712

Author

Rana, Zaker, Kamran, Sophia C., Shetty, Amol C., Sutera, Philip, Song, Yang, Bazyar, Soha, Solanki, Abhishek A., Simko, Jeffry P., Pollack, Alan, McConkey, David, Kates, Max, Siddiqui, M. Minhaj, Hiken, Jeffrey, Earls, Jon, Messina, David, Mouw, Kent W., Miyamoto, David, Shipley, William U., Michaelson, M. Dror, Zietman, Anthony, Coen, John J., Dahl, Douglas M., Jani, Ashesh B., Souhami, Luis, Chang, Brian K., Lee, R. Jeffrey, Pham, Huong, Marshall, David T., Shen, Xinglei, Pugh, Stephanie L., Feng, Felix Y., Efstathiou, Jason A., Tran, Phuoc T., and Deek, Matthew P.

Abstract

A novel transcriptional profiling platform revealed that gene expression consistent with high immune-cell infiltration and of specific genes associated with T-cell infiltration or IFNγ signaling was correlated with better survival following chemoradiation for muscle-invasive bladder cancer.

Published
2024
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16. Trait Mindfulness and Social Support Predict Lower Perceived Stress Burden in Patients Undergoing Radiation Therapy.

Author

Cooper DJ, Eckstein J, Sidiqi B, Rana ZH, Matarangas A, Shah A, Chacko N, Mancuso J, Minutoli T, Zinkin A, Sharma K, Mehta R, Potters L, and Parashar B

Abstract

Purpose: Cancer diagnosis and treatment, including radiation therapy (RT), cause significant patient stress. Mindfulness and social support have been shown to help manage the psychological effects of cancer treatment. The objective of our study was to determine the sociodemographic and clinical factors associated with stress burden in patients receiving RT., Methods and Materials: Patients receiving RT for cancer at a single institution were given a 3-section survey to complete during the first on-treatment visit. The survey included the Perceived Stress Scale, Medical Outcomes Study Social Support Survey, and Mindfulness Attention Awareness Scale, which were used to measure stress, social support, and trait mindfulness, respectively. Linear regression analysis was performed to determine associations between perceived stress and age, patient sex, race and ethnicity, treatment intent, disease site, trait mindfulness, and social support. Factors significant in univariable analysis were analyzed with a multivariable analysis., Results: A total of 93 patients undergoing RT at a tertiary care academic institution were recruited from July to September 2019. Median scores for Perceived Stress Scale, Medical Outcomes Study Social Support Survey, and Mindfulness Attention Awareness Scale were 14.6 (range, 0-31; SD, 6.9), 4.2 (range, 1-5; SD, 1.0), and 5.1 (range, 3.1-6.0; SD, 0.8), respectively. On univariable analysis, mindfulness and social support were associated with decreased stress burden, and female sex and palliative intent were associated with increased stress burden. These factors all maintained significance in multivariable analysis., Conclusions: These results suggest measures to improve mindfulness and perceived social support, such as mindfulness meditation and psychoeducational approaches, may lessen the stress burden and improve quality of life for patients undergoing RT. Future studies should analyze the longitudinal impact of individual patient characteristics, including patient sex and treatment intent, to better understand their effects on psychological maladjustment during cancer care., Competing Interests: None., (© 2024 The Authors.)

Published
2024
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