5 results on '"Ravikumar, Reena"'
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2. Comment on “Pancreatectomy With Arterial Resection for Pancreatic Adenocarcinoma: How Can It Be Done Safely and With Which Outcomes?”
- Author
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Robertson, Francis P., Ravikumar, Reena, and Wigmore, Stephen J.
- Published
- 2021
- Full Text
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3. Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
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Fusai, Giuseppe Kito, Ferrone, Cristina, Raptis, Dimitri Aristotle, Abu Hilal, Mohamed, Bassi, Claudio, Besselink, Marc, Conlon, Kevin, Davidson, Brian, Del Chiaro, Marco, Dervenis, Christos, Frigerio, Isabella, Falconi, Massimo, Hackert, Thilo, Harrison, Ewen M., Shrikhande, Shailesh V, Siriwardena, Ajith, Smith, Martin, Wolfgang, Christopher, Borakati, Aditya, Balci, Deniz, Elhadi, Muhammed, Salinas, Camila Hidalgo, Machairas, Nikolaos, Marchegiani, Giovanni, Oba, Atsushi, Oberkofler, Christian, Passas, Ioannis, Ravikumar, Reena, Sanchez Velazquez, Patricia, de Santibanes, Martin, Schnitzbauer, Andreas Anton, Soggiu, Fiammetta, Tamburrino, Domenico, Tinguely, Pascale, Wei, Alice, Zachiotis, Marinos, Bentabak, Kamel, Kacimi, Salah Eddine, Nikfarjam, Mehrdad, Shcherba, Aliaksei, Sergeant, Gregory, Coelho, Gustavo, Torres, Orlando, Belev, Nikolay, Fabrice, Burundi, Tang, Ephraim, Martin, Janet, Diaz, Christian, Devaud, Nicolas, Wei, Kongyuan, Hendi, Maher, Mikulic, Danko, Gouvas, Nikolaos, Christophides, Thalis, Nikov, Andrej, Fathallah, Dalia, Saad, Mahmoud, Tammik, Olav, Huhta, Heikki, Sulpice, Laurent, Lupinacci, Renato, Demetrashvili, Zaza, Stavrou, Gregor A., Felekouras, Evangelos, Papaziogas, Vasileios, Misra, Sanjeev, Diponegoro, Erik Prabowo, Hashim, Hashim Talib, Al-Sader, Maytham Al-Juaifari, Satoi, Sohei, Obeidat, Khaled, Mohsen, Maram, Fakhradiyev, Ildar, Han, Ho-Seong, Khalife, Mohamad, Dulskas, Audrius, Bong, Jin, Ghani, Shahi, Eduardo Padilla, Alejandro, Melchor-Ruan, Javier, Erdene, Sarnai, Benkabbou, Amine, Nashidengo, Pueya, Koea, Jonathan, Adeyeye, Ademola, Alatise, Olusegun, Ullah, Sami, Abu Jayyab, Mustafa, Amro, Sarah, Alnammourah, Walaa Mohammed, The, Catherine, Pedziwiatr, Michal, Polkowski, Wojciech, Barbu, Sorin Traian, Karamarkovic, Aleksandar, Galun, Daniel, Goh, Brian K. P., Trotovsek, Blaz, Omoshoro-Jones, Jones, Ielpo, Benedetto, Abdelmageed, Abdelfatah, Sandström, Per A, Cristaudi, Alessandra, Gloor, Beat, Kuemmerli, Christoph, Tishreen, Alaa Hamdan, Chaaban, Mohammad Karam, Wu, Chien Hui, Jen, Po-Chih Yang Fu, Houssem, Ammar, Baraket, Oussama, Coker, Ahmet, Taylor, Mark, Jamieson, Nigel, Iype, Satheesh, Giorgakis, Emmanouil, Qadan, Motaz, Ganai, Sabha, Al-Naggar, Hamza, Chihaka, Onesai, Fusai, Giuseppe Kito, Ferrone, Cristina, Raptis, Dimitri Aristotle, Abu Hilal, Mohamed, Bassi, Claudio, Besselink, Marc, Conlon, Kevin, Davidson, Brian, Del Chiaro, Marco, Dervenis, Christos, Frigerio, Isabella, Falconi, Massimo, Hackert, Thilo, Harrison, Ewen M., Shrikhande, Shailesh V, Siriwardena, Ajith, Smith, Martin, Wolfgang, Christopher, Borakati, Aditya, Balci, Deniz, Elhadi, Muhammed, Salinas, Camila Hidalgo, Machairas, Nikolaos, Marchegiani, Giovanni, Oba, Atsushi, Oberkofler, Christian, Passas, Ioannis, Ravikumar, Reena, Sanchez Velazquez, Patricia, de Santibanes, Martin, Schnitzbauer, Andreas Anton, Soggiu, Fiammetta, Tamburrino, Domenico, Tinguely, Pascale, Wei, Alice, Zachiotis, Marinos, Bentabak, Kamel, Kacimi, Salah Eddine, Nikfarjam, Mehrdad, Shcherba, Aliaksei, Sergeant, Gregory, Coelho, Gustavo, Torres, Orlando, Belev, Nikolay, Fabrice, Burundi, Tang, Ephraim, Martin, Janet, Diaz, Christian, Devaud, Nicolas, Wei, Kongyuan, Hendi, Maher, Mikulic, Danko, Gouvas, Nikolaos, Christophides, Thalis, Nikov, Andrej, Fathallah, Dalia, Saad, Mahmoud, Tammik, Olav, Huhta, Heikki, Sulpice, Laurent, Lupinacci, Renato, Demetrashvili, Zaza, Stavrou, Gregor A., Felekouras, Evangelos, Papaziogas, Vasileios, Misra, Sanjeev, Diponegoro, Erik Prabowo, Hashim, Hashim Talib, Al-Sader, Maytham Al-Juaifari, Satoi, Sohei, Obeidat, Khaled, Mohsen, Maram, Fakhradiyev, Ildar, Han, Ho-Seong, Khalife, Mohamad, Dulskas, Audrius, Bong, Jin, Ghani, Shahi, Eduardo Padilla, Alejandro, Melchor-Ruan, Javier, Erdene, Sarnai, Benkabbou, Amine, Nashidengo, Pueya, Koea, Jonathan, Adeyeye, Ademola, Alatise, Olusegun, Ullah, Sami, Abu Jayyab, Mustafa, Amro, Sarah, Alnammourah, Walaa Mohammed, The, Catherine, Pedziwiatr, Michal, Polkowski, Wojciech, Barbu, Sorin Traian, Karamarkovic, Aleksandar, Galun, Daniel, Goh, Brian K. P., Trotovsek, Blaz, Omoshoro-Jones, Jones, Ielpo, Benedetto, Abdelmageed, Abdelfatah, Sandström, Per A, Cristaudi, Alessandra, Gloor, Beat, Kuemmerli, Christoph, Tishreen, Alaa Hamdan, Chaaban, Mohammad Karam, Wu, Chien Hui, Jen, Po-Chih Yang Fu, Houssem, Ammar, Baraket, Oussama, Coker, Ahmet, Taylor, Mark, Jamieson, Nigel, Iype, Satheesh, Giorgakis, Emmanouil, Qadan, Motaz, Ganai, Sabha, Al-Naggar, Hamza, and Chihaka, Onesai
- Abstract
Background: Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized centres. The aim of this study was to evaluate the outcomes following pancreatic surgery worldwide. Methods: This was an international, prospective, multicentre, cross-sectional snapshot study of consecutive patients undergoing pancreatic operations worldwide in a 3-month interval in 2021. The primary outcome was postoperative mortality within 90 days of surgery. Multivariable logistic regression was used to explore relationships with Human Development Index (HDI) and other parameters. Results: A total of 4223 patients from 67 countries were analysed. A complication of any severity was detected in 68.7 percent of patients (2901 of 4223). Major complication rates (Clavien-Dindo grade at least IIIa) were 24, 18, and 27 percent, and mortality rates were 10, 5, and 5 per cent in low-to-middle-, high-, and very high-HDI countries respectively. The 90-day postoperative mortality rate was 5.4 per cent (229 of 4223) overall, but was significantly higher in the low-to-middle-HDI group (adjusted OR 2.88, 95 per cent c.i. 1.80 to 4.48). The overall failure-to-rescue rate was 21 percent; however, it was 41 per cent in low-to-middle-compared with 19 per cent in very high-HDI countries. Conclusion: Excess mortality in low-to-middle-HDI countries could be attributable to failure to rescue of patients from severe complications. The authors call for a collaborative response from international and regional associations of pancreatic surgeons to address management related to death from postoperative complications to tackle the global disparities in the outcomes of pancreatic surgery (NCT04652271; ISRCTN95140761)., Funding Agencies|Fiorina Royal Free Charity, London, UK; Swiss Pancreas Foundation, Berne, Switzerland
- Published
- 2023
- Full Text
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4. The Impact of Neoadjuvant Treatment on Survival in Patients Undergoing Pancreatoduodenectomy With Concomitant Portomesenteric Venous Resection: An International Multicenter Analysis
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Machairas, Nikolaos, Raptis, Dimitri A, Velázquez, Patricia Sánchez, Sauvanet, Alain, Rueda de Leon, Alexandra, Oba, Atsushi, Koerkamp, Bas Groot, Lovasik, Brendan, Chan, Carlos, Yeo, Charles J., Bassi, Claudio, Ferrone, Cristina R., Kooby, David, Moskal, David, Tamburrino, Domenico, Yoon, Dong-Sup, Barroso, Eduardo, de Santibañes, Eduardo, Kauffmann, Emanuele F., Vigia, Emanuel, Robin, Fabien, Casciani, Fabio, Burdío, Fernando, Belfiori, Giulio, Malleo, Giuseppe, Lavu, Harish, Hartog, Hermien, Hwang, Ho-Kyoung, Han, Ho-Seong, Marques, Hugo P., Poves, Ignasi, Domínguez-Rosado, Ismael, Park, Joon-Seong, Lillemoe, Keith D., Roberts, Keith, Sulpice, Laurent, Besselink, Marc G., Abuawwad, Mahmoud, Del Chiaro, Marco, de Santibañes, Martin, Falconi, Massimo, D'Silva, Mizelle, Silva, Michael, Hilal, Mohammed Abu, Qadan, Motaz, Sell, Naomi M., Beghdadi, Nassiba, Napoli, Niccolò, Busch, Olivier R. C., Mazza, Oscar, Muiesan, Paolo, Müller, Philip C., Ravikumar, Reena, Schulick, Richard, Powell-Brett, Sarah, Abbas, Syed Hussain, Mackay, Tara M., Stoop, Thomas F., Gallagher, Tom K., Boggi, Ugo, van Eijck, Casper, Clavien, Pierre-Alain, Conlon, Kevin C. P., and Fusai, Giuseppe Kito
- Abstract
Supplemental Digital Content is available in the text
- Published
- 2021
- Full Text
- View/download PDF
5. Severe Cholestasis Predicts Recurrent Primary Sclerosing Cholangitis Following Liver Transplantation.
- Author
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Aziz B, Kok B, Cheah M, Lytvyak E, Moctezuma-Velazquez C, Wasilenko S, Tsochatzis E, Ravikumar R, Jose S, Allison M, Gunson B, Manas D, Monaco A, Mirza D, Fusai G, Owen N, Thorburn D, Roberts K, Srinivasan P, Wigmore S, Athale A, Creamer F, Fernando B, Iyer V, Madanur M, Sen G, Montano-Loza AJ, Hansen B, and Mason AL
- Abstract
Background Aims: Primary sclerosing cholangitis (PSC) may reoccur following liver transplantation (LT) and the diagnosis established once imaging studies demonstrate the diagnostic cholangiographic appearance. To evaluate whether the development of recurrent PSC (rPSC) is associated with cholestasis soon after LT, we studied whether changes in hepatic biochemistry within the first 12 months were linked with the development of rPSC and graft loss., Methods: We conducted a retrospective cohort analysis of 158 transplant recipients with PSC in Canada, and 549 PSC transplant recipients from the United Kingdom. We evaluated serum liver tests within 12 months after LT and the subsequent development of a cholangiographic diagnosis of rPSC as a time-dependent covariate using Cox regression. Severe cholestasis was defined as either alkaline phosphatase> 3xupper limit of normal or total bilirubin> 100 μmol/L., Results: Patients who developed rPSC were more likely to have severe cholestasis versus those without at 3 months (20.5% vs 8.2%, p=0.011), at 6 months (17.9% vs. 10.0%, p=0.026) and 12 months (15.4% vs. 7.8%, p=0.051) in the Canadian cohort and at 12 months in the UK cohort (27.9% vs. 12.6%, p<0.0001). By multivariable analysis, development of severe cholestasis in the Canadian cohort at 3 months (HR=2.41, p=0.046) and in the UK cohort at 12 months (HR=3.141, p<0.0001) were both associated with rPSC. Severe cholestasis at 3 months in the Canadian cohort was predictive of graft loss (HR=3.88, p=0.0001)., Conclusions: The development of cholestasis within 3 to 12 months following LT was predictive of rPSC and graft loss., (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology.)
- Published
- 2024
- Full Text
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