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Xipapillomavirus includes a group of viruses almost exclusively reported in both beef cattle and dairy breeding, in which they induce papillomatosis and occasionally malignant tumors. Bovine papillomaviruses (BPVs) infection impacts greatly on animal productions, and this is amplified by their cosmopolitan distribution. Cutaneous proliferative lesions in bovines can relate to leather depreciation and impaired milk production by giving rise to obstruction of the teat and hygiene limitations, often leading to hemorrhagic mastitis. This study reports the identification of a novel Xipapillomavirus type associated with udder papilloma in a Jersey cow in Costa Rica. Viral genome was fully sequenced and molecularly characterized. Histopathology and viral phylogeny and evolution are also presented and discussed by comparison with already described BPVs. Based on results, a novel Xipapillomavirus type, namely BPV30, is proposed. BPV30 is a typical Xipapillomavirus 2 most similar to BPV12, from which it separated roughly 18 million years ago. The absence of E6 and the presence of E10 in BPV30 confirm an E6 loss occurring along the clade leading to BPV12. The identification of this novel BPV is fundamental to the development of specific prophylactic tools, which represent the most effective weapon to fight viral circulation, to prevent infections, and eventually controlling associated proliferative lesions. Los xipapilomavirus comprenden un grupo de virus señalados casi exclusivamente en el ganado vacuno de carne y en la cría de ganado lechero, en los que inducen papilomatosis y ocasionalmente tumores malignos. La infección por los papilomavirus bovinos (BPV) tiene un gran impacto en las producciones animales, que se ve amplificado por su distribución cosmopolita. Las lesiones proliferativas cutáneas en los bovinos pueden relacionarse con la depreciación de la piel y el deterioro de la producción de leche al dar lugar a la obstrucción del pezón y a limitaciones higiénicas, lo que a menudo conduce a la mastitis hemorrágica. En este estudio se informa de la identificación de un nuevo tipo de Xipapillomavirus asociado al papiloma de la ubre en una vaca Jersey de Costa Rica. El genoma viral fue completamente secuenciado y caracterizado molecularmente. También se presentan y discuten la histopatología y la filogenia y evolución virales mediante la comparación con los BPV ya descritos. A partir de los resultados, se propone un nuevo tipo de Xipapillomavirus, el BPV30. El BPV30 es un Xipapillomavirus 2 típico muy similar al BPV12, del que se separó hace aproximadamente 18 millones de años. La ausencia de E6 y la presencia de E10 en el BPV30 confirman una pérdida de E6 a lo largo del clado que lleva al BPV12. La identificación de este nuevo BPV es fundamental para el desarrollo de herramientas profilácticas específicas, que representan el arma más eficaz para luchar contra la circulación viral, prevenir las infecciones y, eventualmente, controlar las lesiones proliferativas asociadas. Universidad Nacional, Costa Rica Escuela de Medicina Veterinaria

Physical inactivity (PI) and sedentary behaviours constitute a global health problem that has negative consequences for health and is also considered the fourth leading risk factor for global mortality. A European project named ‘Professional and Personal Experience through Lifelong Learning and Regular Sport’ aims to encourage voluntary participation in sporting activities to achieve its benefits on health. First, a report will be carried out on the effects of physical activity (PA) or inactivity on health, which is often linked to school failure, obesity, self-esteem, etc. The data will be obtained through a completely anonymous online sport and health questionnaire, addressed to all profiles. The data collected through this survey will serve as a basis for understanding the reality of Europeans in terms of quality of life, demographics, physical fitness, and other factors. It is also intended to design a handbook with recommendations for improving health holistically through PA. Finally, the goal is to translate this project into a teaching system for sports professionals, so that they can transfer this knowledge as educational methods to improve people’s health, while adapting it to the particularities of each country, i.e., to provide these sports professionals with tools to train other people.