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Your search keyword '"Rojas, Ernesto"' showing total 9 results
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9 results on '"Rojas, Ernesto"'

2. Abstract B053: The role of whole genome doubling in immune escape in TNBC

Author

Foidart, Pierre, primary, Li, Zheqi, additional, Seehawer, Marco, additional, Nishida, Jun, additional, Rojas, Ernesto, additional, Bui, Triet, additional, Yan, Pengze, additional, Goyette, Marie-Anne, additional, Stevens, Laura, additional, Huang, Xiao-Yun, additional, Anand, Jayati, additional, Nanjangud, Gouri, additional, Xie, Yingtian, additional, Qiu, Xintao, additional, Cejas, Paloma, additional, Long, Henry, additional, and Polyak, Kornelia, additional

Published
2024
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4. Cutaneous leishmaniasis treatment and therapeutic outcomes in special populations: A collaborative retrospective study

Author

Castro, Maria del Mar, primary, Rode, Joelle, additional, Machado, Paulo R. L., additional, Llanos-Cuentas, Alejandro, additional, Hueb, Marcia, additional, Cota, Gláucia, additional, Rojas, Isis Valentina, additional, Orobio, Yenifer, additional, Oviedo Sarmiento, Oscar, additional, Rojas, Ernesto, additional, Quintero, Juliana, additional, Pimentel, Maria Inês Fernandes, additional, Soto, Jaime, additional, Suprien, Carvel, additional, Alvarez, Fiorela, additional, Ramos, Ana Pilar, additional, Arantes, Rayssa Basílio dos Santos, additional, da Silva, Rosiana Estéfane, additional, Arenas, Claudia Marcela, additional, Vélez, Ivan Darío, additional, Lyra, Marcelo Rosandiski, additional, Saravia, Nancy Gore, additional, Arana, Byron, additional, and Alexander, Neal, additional

Published
2023
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5. Usefulness of Matrix-Assisted Laser Desorption/Ionization-Time of Flight Mass Spectrometry in the Characterization of Leishmania Strains Causing Tegumentary Leishmaniasis in Bolivia versus hsp70 Gene Sequencing

Author

Torrico, Mary Cruz, primary, Fernández-Arévalo, Anna, additional, Ballart, Cristina, additional, Solano, Marco, additional, Rojas, Ernesto, additional, Abras, Alba, additional, Gonzales, Fabiola, additional, Arnau, Albert, additional, Tebar, Silvia, additional, Llovet, Teresa, additional, Lozano, Daniel, additional, Ariza-Vioque, Eva, additional, Gascón, Joaquim, additional, Picado, Albert, additional, Torrico, Faustino, additional, Muñoz, Carmen, additional, and Gállego, Montserrat, additional

Published
2023
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6. Abstract A020: Histone modification by Kmt2c and Kmt2d regulate metastasis in triple-negative breast cancer in vivo

Author

Seehawer, Marco, primary, Li, Zheqi, additional, Nishida, Jun, additional, Cejas, Paloma, additional, Reiter, Andrew, additional, Goldman, Seth, additional, Foidart, Pierre, additional, Rojas, Ernesto, additional, Papanastasiou, Malvina, additional, Adelman, Karen, additional, Long, Henry, additional, and Polyak, Kornelia, additional

Published
2022
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9. Tegumentary leishmaniasis by Leishmania braziliensis complex in Cochabamba, Bolivia including the presence of L. braziliensis outlier: Tegumentary leishmaniasis in Cochabamba, Bolivia.

Author

Torrico, Mary Cruz, Fernández‐Arévalo, Anna, Ballart, Cristina, Solano, Marco, Rojas, Ernesto, Ariza, Eva, Tebar, Silvia, Lozano, Daniel, Abras, Alba, Gascón, Joaquim, Picado, Albert, Muñoz, Carmen, Torrico, Faustino, and Gállego, Montserrat

Subjects
LEISHMANIASIS, LEISHMANIA, SEQUENCE alignment, TREATMENT failure
Abstract

Leishmaniasis is caused by protozoans of the Leishmania genus, which includes more than 20 species capable of infecting humans worldwide. In the Americas, the most widespread specie is L. braziliensis, present in 18 countries including Bolivia. The taxonomic position of the L. braziliensis complex has been a subject of controversy, complicated further by the recent identification of a particular subpopulation named L. braziliensis atypical or outlier. The aim of this study was to carry out a systematic analysis of the L. braziliensis complex in Bolivia and to describe the associated clinical characteristics. Forty‐one strains were analyzed by sequencing an amplified 1245 bp fragment of the hsp70 gene, which allowed its identification as: 24 (59%) L. braziliensis, 16 (39%) L. braziliensis outlier, and one (2%) L. peruviana. In a dendrogram constructed, L. braziliensis and L. peruviana are grouped in the same cluster, whilst L. braziliensis outlier appears in a separate branch. Sequence alignment allowed the identification of five non‐polymorphic nucleotide positions (288, 297, 642, 993, and 1213) that discriminate L. braziliensis and L. peruviana from L. braziliensis outlier. Moreover, nucleotide positions 51 and 561 enable L. peruviana to be discriminated from the other two taxa. A greater diversity was observed in L. braziliensis outlier than in L. braziliensis‐L. peruviana. The 41 strains came from 32 patients with tegumentary leishmaniasis, among which 22 patients (69%) presented cutaneous lesions (11 caused by L. braziliensis and 11 by L. braziliensis outlier) and 10 patients (31%) mucocutaneous lesions (eight caused by L. braziliensis, one by L. braziliensis outlier, and one by L. peruviana). Nine patients (28%) simultaneously provided two isolates, each from a separate lesion, and in each case the same genotype was identified in both. Treatment failure was observed in six patients infected with L. braziliensis and one patient with L. peruviana. [ABSTRACT FROM AUTHOR]

Published
2022
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