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8,079 results on '"Salmon AS"'

1. The R-Vessel-X Project

Author: Affane, Abir, Chetoui, Mohamed Amine, Lamy, Jonas, Lienemann, Guillaume, Peron, Raphaël, Beaurepaire, P., Dollé, Guillaume, Lèbre, Marie-Ange, Magnin, Benoit, Merveille, Odyssée, Morvan, Mathilde, Ngo, Phuc, Pelletier, Thibault, Rositi, Hugo, Salmon, Stéphanie, Finet, Julien, Kerautret, Bertrand, Passat, Nicolas, and Vacavant, Antoine
Subjects: Electrical Engineering and Systems Science - Image and Video Processing
Abstract: 1) Objectives: This technical report presents a synthetic summary and the principal outcomes of the project R-Vessel-X ("Robust vascular network extraction and understanding within hepatic biomedical images") funded by the French Agence Nationale de la Recherche, and developed between 2019 and 2023. 2) Material and methods: We used datasets and tools publicly available such as IRCAD, Bullitt or VascuSynth toobtain real or synthetic angiographic images. The main contributions lie in the field of 3D angiographic image analysis: filtering, segmentation, modeling and simulation, with a specific focus on the liver. 3) Results: We paid a particular attention to open-source software diffusion of the developed methods, by means of 3D Slicer plugins for the liver anatomy segmentation (SlicerRVXLiverSegmentation) and vesselness filtering (Slicer-RVXVesselnessFilters), and an online demo for the generation of synthetic and realistic vessels in 2D and 3D (OpenCCO). 4) Conclusion: The R-Vessel-X project provided extensive research outcomes, covering various topics related to 3D angiographic image analysis, such as filtering, segmentation, modeling and simulation. We also developed open-source and free softwares so that the research communities in biomedical engineering can use these results in their future research., Comment: Innovation and Research in BioMedical engineering, In press
Published: 2025

2. Debugging Without Error Messages: How LLM Prompting Strategy Affects Programming Error Explanation Effectiveness

Author: Salmon, Audrey, Hammer, Katie, Santos, Eddie Antonio, and Becker, Brett A.
Subjects: Computer Science - Software Engineering, Computer Science - Human-Computer Interaction
Abstract: Making errors is part of the programming process -- even for the most seasoned professionals. Novices in particular are bound to make many errors while learning. It is well known that traditional (compiler/interpreter) programming error messages have been less than helpful for many novices and can have effects such as being frustrating, containing confusing jargon, and being downright misleading. Recent work has found that large language models (LLMs) can generate excellent error explanations, but that the effectiveness of these error messages heavily depends on whether the LLM has been provided with context -- typically the original source code where the problem occurred. Knowing that programming error messages can be misleading and/or contain that serves little-to-no use (particularly for novices) we explore the reverse: what happens when GPT-3.5 is prompted for error explanations on just the erroneous source code itself -- original compiler/interpreter produced error message excluded. We utilized various strategies to make more effective error explanations, including one-shot prompting and fine-tuning. We report the baseline results of how effective the error explanations are at providing feedback, as well as how various prompting strategies might improve the explanations' effectiveness. Our results can help educators by understanding how LLMs respond to such prompts that novices are bound to make, and hopefully lead to more effective use of Generative AI in the classroom., Comment: 7 pages, 1 figure
Published: 2025

3. OpenAI o1 System Card

Author: OpenAI, Jaech, Aaron, Kalai, Adam, Lerer, Adam, Richardson, Adam, El-Kishky, Ahmed, Low, Aiden, Helyar, Alec, Madry, Aleksander, Beutel, Alex, Carney, Alex, Iftimie, Alex, Karpenko, Alex, Passos, Alex Tachard, Neitz, Alexander, Prokofiev, Alexander, Wei, Alexander, Tam, Allison, Bennett, Ally, Kumar, Ananya, Saraiva, Andre, Vallone, Andrea, Duberstein, Andrew, Kondrich, Andrew, Mishchenko, Andrey, Applebaum, Andy, Jiang, Angela, Nair, Ashvin, Zoph, Barret, Ghorbani, Behrooz, Rossen, Ben, Sokolowsky, Benjamin, Barak, Boaz, McGrew, Bob, Minaiev, Borys, Hao, Botao, Baker, Bowen, Houghton, Brandon, McKinzie, Brandon, Eastman, Brydon, Lugaresi, Camillo, Bassin, Cary, Hudson, Cary, Li, Chak Ming, de Bourcy, Charles, Voss, Chelsea, Shen, Chen, Zhang, Chong, Koch, Chris, Orsinger, Chris, Hesse, Christopher, Fischer, Claudia, Chan, Clive, Roberts, Dan, Kappler, Daniel, Levy, Daniel, Selsam, Daniel, Dohan, David, Farhi, David, Mely, David, Robinson, David, Tsipras, Dimitris, Li, Doug, Oprica, Dragos, Freeman, Eben, Zhang, Eddie, Wong, Edmund, Proehl, Elizabeth, Cheung, Enoch, Mitchell, Eric, Wallace, Eric, Ritter, Erik, Mays, Evan, Wang, Fan, Such, Felipe Petroski, Raso, Filippo, Leoni, Florencia, Tsimpourlas, Foivos, Song, Francis, von Lohmann, Fred, Sulit, Freddie, Salmon, Geoff, Parascandolo, Giambattista, Chabot, Gildas, Zhao, Grace, Brockman, Greg, Leclerc, Guillaume, Salman, Hadi, Bao, Haiming, Sheng, Hao, Andrin, Hart, Bagherinezhad, Hessam, Ren, Hongyu, Lightman, Hunter, Chung, Hyung Won, Kivlichan, Ian, O'Connell, Ian, Osband, Ian, Gilaberte, Ignasi Clavera, Akkaya, Ilge, Kostrikov, Ilya, Sutskever, Ilya, Kofman, Irina, Pachocki, Jakub, Lennon, James, Wei, Jason, Harb, Jean, Twore, Jerry, Feng, Jiacheng, Yu, Jiahui, Weng, Jiayi, Tang, Jie, Yu, Jieqi, Candela, Joaquin Quiñonero, Palermo, Joe, Parish, Joel, Heidecke, Johannes, Hallman, John, Rizzo, John, Gordon, Jonathan, Uesato, Jonathan, Ward, Jonathan, Huizinga, Joost, Wang, Julie, Chen, Kai, Xiao, Kai, Singhal, Karan, Nguyen, Karina, Cobbe, Karl, Shi, Katy, Wood, Kayla, Rimbach, Kendra, Gu-Lemberg, Keren, Liu, Kevin, Lu, Kevin, Stone, Kevin, Yu, Kevin, Ahmad, Lama, Yang, Lauren, Liu, Leo, Maksin, Leon, Ho, Leyton, Fedus, Liam, Weng, Lilian, Li, Linden, McCallum, Lindsay, Held, Lindsey, Kuhn, Lorenz, Kondraciuk, Lukas, Kaiser, Lukasz, Metz, Luke, Boyd, Madelaine, Trebacz, Maja, Joglekar, Manas, Chen, Mark, Tintor, Marko, Meyer, Mason, Jones, Matt, Kaufer, Matt, Schwarzer, Max, Shah, Meghan, Yatbaz, Mehmet, Guan, Melody Y., Xu, Mengyuan, Yan, Mengyuan, Glaese, Mia, Chen, Mianna, Lampe, Michael, Malek, Michael, Wang, Michele, Fradin, Michelle, McClay, Mike, Pavlov, Mikhail, Wang, Miles, Wang, Mingxuan, Murati, Mira, Bavarian, Mo, Rohaninejad, Mostafa, McAleese, Nat, Chowdhury, Neil, Ryder, Nick, Tezak, Nikolas, Brown, Noam, Nachum, Ofir, Boiko, Oleg, Murk, Oleg, Watkins, Olivia, Chao, Patrick, Ashbourne, Paul, Izmailov, Pavel, Zhokhov, Peter, Dias, Rachel, Arora, Rahul, Lin, Randall, Lopes, Rapha Gontijo, Gaon, Raz, Miyara, Reah, Leike, Reimar, Hwang, Renny, Garg, Rhythm, Brown, Robin, James, Roshan, Shu, Rui, Cheu, Ryan, Greene, Ryan, Jain, Saachi, Altman, Sam, Toizer, Sam, Toyer, Sam, Miserendino, Samuel, Agarwal, Sandhini, Hernandez, Santiago, Baker, Sasha, McKinney, Scott, Yan, Scottie, Zhao, Shengjia, Hu, Shengli, Santurkar, Shibani, Chaudhuri, Shraman Ray, Zhang, Shuyuan, Fu, Siyuan, Papay, Spencer, Lin, Steph, Balaji, Suchir, Sanjeev, Suvansh, Sidor, Szymon, Broda, Tal, Clark, Aidan, Wang, Tao, Gordon, Taylor, Sanders, Ted, Patwardhan, Tejal, Sottiaux, Thibault, Degry, Thomas, Dimson, Thomas, Zheng, Tianhao, Garipov, Timur, Stasi, Tom, Bansal, Trapit, Creech, Trevor, Peterson, Troy, Eloundou, Tyna, Qi, Valerie, Kosaraju, Vineet, Monaco, Vinnie, Pong, Vitchyr, Fomenko, Vlad, Zheng, Weiyi, Zhou, Wenda, McCabe, Wes, Zaremba, Wojciech, Dubois, Yann, Lu, Yinghai, Chen, Yining, Cha, Young, Bai, Yu, He, Yuchen, Zhang, Yuchen, Wang, Yunyun, Shao, Zheng, and Li, Zhuohan
Subjects: Computer Science - Artificial Intelligence
Abstract: The o1 model series is trained with large-scale reinforcement learning to reason using chain of thought. These advanced reasoning capabilities provide new avenues for improving the safety and robustness of our models. In particular, our models can reason about our safety policies in context when responding to potentially unsafe prompts, through deliberative alignment. This leads to state-of-the-art performance on certain benchmarks for risks such as generating illicit advice, choosing stereotyped responses, and succumbing to known jailbreaks. Training models to incorporate a chain of thought before answering has the potential to unlock substantial benefits, while also increasing potential risks that stem from heightened intelligence. Our results underscore the need for building robust alignment methods, extensively stress-testing their efficacy, and maintaining meticulous risk management protocols. This report outlines the safety work carried out for the OpenAI o1 and OpenAI o1-mini models, including safety evaluations, external red teaming, and Preparedness Framework evaluations.
Published: 2024

4. The center of the walled Brauer algebra $B_{r,1}(\delta)$

Author: Chavli, Eirini, De Visscher, Maud, Parker, Alison, Salmon, Sarah, and Wilson, Ulrica
Subjects: Mathematics - Representation Theory, 16U70, 05E05
Abstract: We show that the centre of the walled Brauer algebra $B_{r,1}(\delta)$ over the complex field $\mathbb{C}$, for any parameter $\delta\in \mathbb{C}$, is generated by the supersymmetric polynomials evaluated at the Jucys-Murphy elements. Moreover, we prove that its dimension is independent of the parameter $\delta$.
Published: 2024

5. Discrete harmonics for stream function-vorticity Stokes problem

Author: Dubois, François, Salaün, Michel, and Salmon, Stéphanie
Subjects: Mathematics - Numerical Analysis
Abstract: We consider the bidimensional Stokes problem for incompressible fluids in stream function-vorticity. For this problem, the classical finite elements method of degree one converges only to order one-half for the L2 norm of the vorticity. We propose to use harmonic functions to approach the vorticity along the boundary. Discrete harmonics are functions that are used in practice to derive a new numerical method. We prove that we obtain with this numerical scheme an error of order one for the L2 norm of the vorticity.
Published: 2024

6. CHEOPS observations confirm nodal precession in the WASP-33 system

Author: Smith, A. M. S., Csizmadia, Sz., Van Grootel, V., Lendl, M., Persson, C. M., Olofsson, G., Ehrenreich, D., Günther, M. N., Heitzmann, A., Barros, S. C. C., Bonfanti, A., Brandeker, A., Cabrera, J., Demangeon, O. D. S., Fossati, L., Harre, J. -V., Hooton, M. J., Hoyer, S., Kalman, Sz., Salmon, S., Sousa, S. G., Szabó, Gy. M., Wilson, T. G., Alibert, Y., Alonso, R., Asquier, J., Bárczy, T., Barrado, D., Baumjohann, W., Benz, W., Billot, N., Borsato, L., Broeg, C., Cameron, A. Collier, Correia, A. C. M., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Demory, B. -O., Derekas, A., Edwards, B., Egger, J. A., Erikson, A., Fortier, A., Fridlund, M., Gandolfi, D., Gazeas, K., Gillon, M., Güdel, M., Hasiba, J., Helling, Ch., Isaak, K. G., Kiss, L. L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Magrin, D., Maxted, P. F. L., Merín, B., Mordasini, C., Nascimbeni, V., Ottensamer, R., Pagano, I., Pallé, E., Peter, G., Piazza, D., Piotto, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Rauer, H., Ribas, I., Santos, N. C., Scandariato, G., Ségransan, D., Simon, A. E., Stalport, M., Sulis, S., Udry, S., Ulmer-Moll, S., Venturini, J., Villaver, E., Viotto, V., Walter, I., Walton, N. A., and Wolf, S.
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Aims: We aim to observe the transits and occultations of WASP-33b, which orbits a rapidly-rotating $\delta$ Scuti pulsator, with the goal of measuring the orbital obliquity via the gravity-darkening effect, and constraining the geometric albedo via the occultation depth. Methods: We observed four transits and four occultations with CHEOPS, and employ a variety of techniques to remove the effects of the stellar pulsations from the light curves, as well as the usual CHEOPS systematic effects. We also performed a comprehensive analysis of low-resolution spectral and Gaia data to re-determine the stellar properties of WASP-33. Results: We measure an orbital obliquity 111.3 +0.2 -0.7 degrees, which is consistent with previous measurements made via Doppler tomography. We also measure the planetary impact parameter, and confirm that this parameter is undergoing rapid secular evolution as a result of nodal precession of the planetary orbit. This precession allows us to determine the second-order fluid Love number of the star, which we find agrees well with the predictions of theoretical stellar models. We are unable to robustly measure a unique value of the occultation depth, and emphasise the need for long-baseline observations to better measure the pulsation periods., Comment: 18 pages, 12 figures. Accepted for publication in Astronomy & Astrophysics
Published: 2024

7. A joint effort to discover and characterize two resonant mini Neptunes around TOI-1803 with TESS, HARPS-N and CHEOPS

Author: Zingales, T., Malavolta, L., Borsato, L., Turrini, D., Bonfanti, A., Polychroni, D., Mantovan, G., Nardiello, D., Nascimbeni, V., Lanza, A. F., Bekkelien, A., Sozzetti, A., Broeg, C., Naponiello, L., Lendl, M., Bonomo, A. S., Simon, A. E., Desidera, S., Piotto, G., Mancini, L., Hooton, M. J., Bignamini, A., Egger, J. A., Maggio, A., Alibert, Y., Locci, D., Delrez, L., Biassoni, F., Fossati, L., Cabona, L., Lacedelli, G., Carleo, I., Leonardi, P., Andreuzzi, G., Brandeker, A., Cosentino, R., Correia, A. C. M., Claudi, R., Alonso, R., Damasso, M., Wilson, T. G., Bàrczy, T., Pinamonti, M., Baker, D., Barkaoui, K., Navascues, D. Barrado, Barros, S. C. C., Baumjohann, W., Beck, T., Beichman, C., Benz, W., Bieryla, A., Billot, N., Bosch-Cabot, P., Bouma, L. G., Ciardi, D. R., Cameron, A. Collier, Collins, K. A., Crossfield, Ian J. M., Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Demangeon, O. D. S., Demory, B. O., Derekas, A., Dragomir, D., Edwards, B., Ehrenreich, D., Erikson, A., Falk, B., Fortier, A., Fridlund, M., Fukui, A., Gandolfi, D., Gazeas, K., Gillon, M., Gonzales, E., Gudel, M., Guerra, P., Guunther, M. N., Heitzmann, A., Helling, Ch., Howell, S. B., Isaak, K. G., Jenkins, J., Kiss, L. L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Magrin, D., Matson, R., Matthews, E. C., Maxted, P. F. L., McDermott, S., Munari, M., Mordasini, C., Narita, N., Olofsson, G., Ottensamer, R., Pagano, I., Pallè, E., Peter, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Ratti, F., Rauer, H., Ribas, I., Salmon, S., Santos, N. C., Scandariato, G., Seager, S., Sègransan, D., Smith, A. M. S., Schlieder, J., Schwarz, R. P., Shporer, A., Sousa, S. G., Stalport, M., Steinberger, M., Sulis, S., Szabò, Gy. M., Twicken, J. D., Udry, S., Van Grootel, V., Venturini, J., Villaver, E., Walton, N. A., and Winn, J. N.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: We present the discovery of two mini Neptunes near a 2:1 orbital resonance configuration orbiting the K0 star TOI-1803. We describe their orbital architecture in detail and suggest some possible formation and evolution scenarios. Using CHEOPS, TESS, and HARPS-N datasets we can estimate the radius and the mass of both planets. We used a multidimensional Gaussian Process with a quasi-periodic kernel to disentangle the planetary components from the stellar activity in the HARPS-N dataset. We performed dynamical modeling to explain the orbital configuration and performed planetary formation and evolution simulations. For the least dense planet, we define possible atmospheric characterization scenarios with simulated JWST observations. TOI-1803 b and TOI-1803 c have orbital periods of $\sim$6.3 and $\sim$12.9 days, respectively, residing in close proximity to a 2:1 orbital resonance. Ground-based photometric follow-up observations revealed significant transit timing variations (TTV) with an amplitude of $\sim$10 min and $\sim$40 min, respectively, for planet -b and -c. With the masses computed from the radial velocities data set, we obtained a density of (0.39$\pm$0.10) $\rho_{earth}$ and (0.076$\pm$0.038) $\rho_{earth}$ for planet -b and -c, respectively. TOI-1803 c is among the least dense mini Neptunes currently known, and due to its inflated atmosphere, it is a suitable target for transmission spectroscopy with JWST. We report the discovery of two mini Neptunes close to a 2:1 orbital resonance. The detection of significant TTVs from ground-based photometry opens scenarios for a more precise mass determination. TOI-1803 c is one of the least dense mini Neptune known so far, and it is of great interest among the scientific community since it could constrain our formation scenarios., Comment: 26 Pages, 21 Figures Accepted for Publication in Astronomy & Astrophysics
Published: 2024

8. Contextuality Can be Verified with Noncontextual Experiments

Author: Thio, Jonathan J., Salmon, Wilfred, Barnes, Crispin H. W., De Bièvre, Stephan, and Arvidsson-Shukur, David R. M.
Subjects: Quantum Physics
Abstract: We uncover new features of generalized contextuality by connecting it to the Kirkwood-Dirac (KD) quasiprobability distribution. Quantum states can be represented by KD distributions, which take values in the complex unit disc. Only for ``KD-positive'' states are the KD distributions joint probability distributions. A KD distribution can be measured by a series of weak and projective measurements. We design such an experiment and show that it is contextual iff the underlying state is not KD-positive. We analyze this connection with respect to mixed KD-positive states that cannot be decomposed as convex combinations of pure KD-positive states. Our result is the construction of a noncontextual experiment that enables an experimenter to verify contextuality., Comment: 17 pages, 4 figures
Published: 2024

9. Exploring Foundation Models Fine-Tuning for Cytology Classification

Author: Dausort, Manon, Godelaine, Tiffanie, Zanella, Maxime, Khoury, Karim El, Salmon, Isabelle, and Macq, Benoît
Subjects: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Artificial Intelligence, Computer Science - Computer Vision and Pattern Recognition, Quantitative Biology - Quantitative Methods
Abstract: Cytology slides are essential tools in diagnosing and staging cancer, but their analysis is time-consuming and costly. Foundation models have shown great potential to assist in these tasks. In this paper, we explore how existing foundation models can be applied to cytological classification. More particularly, we focus on low-rank adaptation, a parameter-efficient fine-tuning method suited to few-shot learning. We evaluated five foundation models across four cytological classification datasets. Our results demonstrate that fine-tuning the pre-trained backbones with LoRA significantly improves model performance compared to fine-tuning only the classifier head, achieving state-of-the-art results on both simple and complex classification tasks while requiring fewer data samples., Comment: 5 pages, 2 figures
Published: 2024

10. Pervaporation-driven electrokinetic energy harvesting using poly(dimethylsiloxane) microfluidic chips

Author: Pingulkar, Hrishikesh, Ayela, Cédric, and Salmon, Jean-Baptiste
Subjects: Condensed Matter - Soft Condensed Matter, Physics - Fluid Dynamics
Abstract: Electrokinetic energy harvesting from evaporation-driven flows in porous materials has recently been the subject of numerous studies, particularly with the development of nanomaterials with high conversion efficiencies. The configuration in which the energy conversion element is located upstream of the element which passively drives the evaporative flow has rarely been studied. However, this configuration offers the possibility of increasing the harvested energy simply by increasing the evaporation surface area and/or the hydraulic resistance of the energy conversion element. In this work, we investigate this configuration with poly(dimethylsiloxane) (PDMS) chips playing the role of {\it artificial leaves} driving a pervaporation-induced flow through a polystyrene colloid plug in a submillimetre tube for the energy conversion. With an appropriate design of the venation of the PDMS leaves, we report the first experimental evidence of electrokinetic energy conversion from pervaporation-induced flows, which increases with the pervaporation area. We also provide new insights by demonstrating that this increase is limited by cavitation within the PDMS leaves, which occurs systematically as soon as the water pressure inside the leaf reaches $P_\text{leaf} \simeq 0$~bar. Whatever the cavitation threshold, this phenomenon imposes an intrinsic limit on this configuration, underlining the need for innovative strategies to improve the harvesting of electrokinetic energy by evaporation.
Published: 2024
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11. Associations of perceived neighbourhood and home environments with sedentary behaviour among adolescents in 14 countries: the IPEN adolescent cross sectional observational study.

Author: Anjana, Ranjit, Ranjani, Harish, Cerin, Ester, Akram, Muhammad, Salmon, Jo, Conway, Terry, Cain, Kelli, Pradeepa, Rajendra, Barnett, Anthony, Sit, Cindy, Van Dyck, Delfien, Hino, Adriano, Pizarro, Andreia, Oyeyemi, Adewale, Muda, Wan, Moran, Mika, Troelsen, Jens, Mitáš, Josef, Islam, M, Queralt, Ana, Mohan, Viswanathan, Hinckson, Erica, and Sallis, James
Subjects: Accelerometer, Built environment, Screen time, Sedentary time, Social media, Youth, Adolescent, Child, Female, Humans, Male, Young Adult, Accelerometry, Adolescent Behavior, Cross-Sectional Studies, Environment Design, Exercise, Parents, Residence Characteristics, Screen Time, Sedentary Behavior, Social Media, Surveys and Questionnaires
Abstract: BACKGROUND: Understanding environmental correlates of sedentary behaviour (SB) among young people is important as such data can identify approaches to limit sedentary time. This paper estimates associations of parent-reported neighbourhood and adolescent-reported home environments with SB among adolescents aged 11-19 years from 14 countries. METHODS: In the International Physical activity and the Environment Network (IPEN) Adolescent Study (an observational, cross-sectional multi-country study), adolescents wore a triaxial accelerometer for seven days that assessed sedentary time (ST). Adolescents completed survey measures of sedentary behaviour (SB) related to recreational screen time and sitting time in motor vehicles. Parents and adolescents completed surveys assessing neighbourhood and home environments. Accelerometer based ST was available in 3,982 adolescents while survey data were available for 6,302 dyads. We estimated the total and direct effects of each environmental attribute on ST and SB. Sex of the adolescent and city/country were examined as moderators. RESULTS: The average ST in adolescents from 14 countries ranged from 7.8 to 10.5 h/day. Personal social media was the only significant correlate of total ST across both sexes. With respect to self-reported SB, adolescents accumulated an average of 3.8 h of non-school screen time per day and nearly 40 min of transport-related sitting time. Screen time was associated with all home environment variables, including social media account, as well as land use mix-diversity, traffic safety, and crime safety. Transport-related sitting time was related to land use mix-diversity, recreation facilities, walking facilities, and pedestrian infrastructure, but no home environment variables. City/country and sex were significant moderators of several associations. CONCLUSIONS: Both home and neighbourhood environment features were related to ST and SB. Having social media accounts emerged as a major contributor towards sedentarism in adolescents.
Published: 2024

12. GPT-4o System Card

Author: OpenAI, Hurst, Aaron, Lerer, Adam, Goucher, Adam P., Perelman, Adam, Ramesh, Aditya, Clark, Aidan, Ostrow, AJ, Welihinda, Akila, Hayes, Alan, Radford, Alec, Mądry, Aleksander, Baker-Whitcomb, Alex, Beutel, Alex, Borzunov, Alex, Carney, Alex, Chow, Alex, Kirillov, Alex, Nichol, Alex, Paino, Alex, Renzin, Alex, Passos, Alex Tachard, Kirillov, Alexander, Christakis, Alexi, Conneau, Alexis, Kamali, Ali, Jabri, Allan, Moyer, Allison, Tam, Allison, Crookes, Amadou, Tootoochian, Amin, Tootoonchian, Amin, Kumar, Ananya, Vallone, Andrea, Karpathy, Andrej, Braunstein, Andrew, Cann, Andrew, Codispoti, Andrew, Galu, Andrew, Kondrich, Andrew, Tulloch, Andrew, Mishchenko, Andrey, Baek, Angela, Jiang, Angela, Pelisse, Antoine, Woodford, Antonia, Gosalia, Anuj, Dhar, Arka, Pantuliano, Ashley, Nayak, Avi, Oliver, Avital, Zoph, Barret, Ghorbani, Behrooz, Leimberger, Ben, Rossen, Ben, Sokolowsky, Ben, Wang, Ben, Zweig, Benjamin, Hoover, Beth, Samic, Blake, McGrew, Bob, Spero, Bobby, Giertler, Bogo, Cheng, Bowen, Lightcap, Brad, Walkin, Brandon, Quinn, Brendan, Guarraci, Brian, Hsu, Brian, Kellogg, Bright, Eastman, Brydon, Lugaresi, Camillo, Wainwright, Carroll, Bassin, Cary, Hudson, Cary, Chu, Casey, Nelson, Chad, Li, Chak, Shern, Chan Jun, Conger, Channing, Barette, Charlotte, Voss, Chelsea, Ding, Chen, Lu, Cheng, Zhang, Chong, Beaumont, Chris, Hallacy, Chris, Koch, Chris, Gibson, Christian, Kim, Christina, Choi, Christine, McLeavey, Christine, Hesse, Christopher, Fischer, Claudia, Winter, Clemens, Czarnecki, Coley, Jarvis, Colin, Wei, Colin, Koumouzelis, Constantin, Sherburn, Dane, Kappler, Daniel, Levin, Daniel, Levy, Daniel, Carr, David, Farhi, David, Mely, David, Robinson, David, Sasaki, David, Jin, Denny, Valladares, Dev, Tsipras, Dimitris, Li, Doug, Nguyen, Duc Phong, Findlay, Duncan, Oiwoh, Edede, Wong, Edmund, Asdar, Ehsan, Proehl, Elizabeth, Yang, Elizabeth, Antonow, Eric, Kramer, Eric, Peterson, Eric, Sigler, Eric, Wallace, Eric, Brevdo, Eugene, Mays, Evan, Khorasani, Farzad, Such, Felipe Petroski, Raso, Filippo, Zhang, Francis, von Lohmann, Fred, Sulit, Freddie, Goh, Gabriel, Oden, Gene, Salmon, Geoff, Starace, Giulio, Brockman, Greg, Salman, Hadi, Bao, Haiming, Hu, Haitang, Wong, Hannah, Wang, Haoyu, Schmidt, Heather, Whitney, Heather, Jun, Heewoo, Kirchner, Hendrik, Pinto, Henrique Ponde de Oliveira, Ren, Hongyu, Chang, Huiwen, Chung, Hyung Won, Kivlichan, Ian, O'Connell, Ian, Osband, Ian, Silber, Ian, Sohl, Ian, Okuyucu, Ibrahim, Lan, Ikai, Kostrikov, Ilya, Sutskever, Ilya, Kanitscheider, Ingmar, Gulrajani, Ishaan, Coxon, Jacob, Menick, Jacob, Pachocki, Jakub, Aung, James, Betker, James, Crooks, James, Lennon, James, Kiros, Jamie, Leike, Jan, Park, Jane, Kwon, Jason, Phang, Jason, Teplitz, Jason, Wei, Jason, Wolfe, Jason, Chen, Jay, Harris, Jeff, Varavva, Jenia, Lee, Jessica Gan, Shieh, Jessica, Lin, Ji, Yu, Jiahui, Weng, Jiayi, Tang, Jie, Yu, Jieqi, Jang, Joanne, Candela, Joaquin Quinonero, Beutler, Joe, Landers, Joe, Parish, Joel, Heidecke, Johannes, Schulman, John, Lachman, Jonathan, McKay, Jonathan, Uesato, Jonathan, Ward, Jonathan, Kim, Jong Wook, Huizinga, Joost, Sitkin, Jordan, Kraaijeveld, Jos, Gross, Josh, Kaplan, Josh, Snyder, Josh, Achiam, Joshua, Jiao, Joy, Lee, Joyce, Zhuang, Juntang, Harriman, Justyn, Fricke, Kai, Hayashi, Kai, Singhal, Karan, Shi, Katy, Karthik, Kavin, Wood, Kayla, Rimbach, Kendra, Hsu, Kenny, Nguyen, Kenny, Gu-Lemberg, Keren, Button, Kevin, Liu, Kevin, Howe, Kiel, Muthukumar, Krithika, Luther, Kyle, Ahmad, Lama, Kai, Larry, Itow, Lauren, Workman, Lauren, Pathak, Leher, Chen, Leo, Jing, Li, Guy, Lia, Fedus, Liam, Zhou, Liang, Mamitsuka, Lien, Weng, Lilian, McCallum, Lindsay, Held, Lindsey, Ouyang, Long, Feuvrier, Louis, Zhang, Lu, Kondraciuk, Lukas, Kaiser, Lukasz, Hewitt, Luke, Metz, Luke, Doshi, Lyric, Aflak, Mada, Simens, Maddie, Boyd, Madelaine, Thompson, Madeleine, Dukhan, Marat, Chen, Mark, Gray, Mark, Hudnall, Mark, Zhang, Marvin, Aljubeh, Marwan, Litwin, Mateusz, Zeng, Matthew, Johnson, Max, Shetty, Maya, Gupta, Mayank, Shah, Meghan, Yatbaz, Mehmet, Yang, Meng Jia, Zhong, Mengchao, Glaese, Mia, Chen, Mianna, Janner, Michael, Lampe, Michael, Petrov, Michael, Wu, Michael, Wang, Michele, Fradin, Michelle, Pokrass, Michelle, Castro, Miguel, de Castro, Miguel Oom Temudo, Pavlov, Mikhail, Brundage, Miles, Wang, Miles, Khan, Minal, Murati, Mira, Bavarian, Mo, Lin, Molly, Yesildal, Murat, Soto, Nacho, Gimelshein, Natalia, Cone, Natalie, Staudacher, Natalie, Summers, Natalie, LaFontaine, Natan, Chowdhury, Neil, Ryder, Nick, Stathas, Nick, Turley, Nick, Tezak, Nik, Felix, Niko, Kudige, Nithanth, Keskar, Nitish, Deutsch, Noah, Bundick, Noel, Puckett, Nora, Nachum, Ofir, Okelola, Ola, Boiko, Oleg, Murk, Oleg, Jaffe, Oliver, Watkins, Olivia, Godement, Olivier, Campbell-Moore, Owen, Chao, Patrick, McMillan, Paul, Belov, Pavel, Su, Peng, Bak, Peter, Bakkum, Peter, Deng, Peter, Dolan, Peter, Hoeschele, Peter, Welinder, Peter, Tillet, Phil, Pronin, Philip, Tillet, Philippe, Dhariwal, Prafulla, Yuan, Qiming, Dias, Rachel, Lim, Rachel, Arora, Rahul, Troll, Rajan, Lin, Randall, Lopes, Rapha Gontijo, Puri, Raul, Miyara, Reah, Leike, Reimar, Gaubert, Renaud, Zamani, Reza, Wang, Ricky, Donnelly, Rob, Honsby, Rob, Smith, Rocky, Sahai, Rohan, Ramchandani, Rohit, Huet, Romain, Carmichael, Rory, Zellers, Rowan, Chen, Roy, Chen, Ruby, Nigmatullin, Ruslan, Cheu, Ryan, Jain, Saachi, Altman, Sam, Schoenholz, Sam, Toizer, Sam, Miserendino, Samuel, Agarwal, Sandhini, Culver, Sara, Ethersmith, Scott, Gray, Scott, Grove, Sean, Metzger, Sean, Hermani, Shamez, Jain, Shantanu, Zhao, Shengjia, Wu, Sherwin, Jomoto, Shino, Wu, Shirong, Shuaiqi, Xia, Phene, Sonia, Papay, Spencer, Narayanan, Srinivas, Coffey, Steve, Lee, Steve, Hall, Stewart, Balaji, Suchir, Broda, Tal, Stramer, Tal, Xu, Tao, Gogineni, Tarun, Christianson, Taya, Sanders, Ted, Patwardhan, Tejal, Cunninghman, Thomas, Degry, Thomas, Dimson, Thomas, Raoux, Thomas, Shadwell, Thomas, Zheng, Tianhao, Underwood, Todd, Markov, Todor, Sherbakov, Toki, Rubin, Tom, Stasi, Tom, Kaftan, Tomer, Heywood, Tristan, Peterson, Troy, Walters, Tyce, Eloundou, Tyna, Qi, Valerie, Moeller, Veit, Monaco, Vinnie, Kuo, Vishal, Fomenko, Vlad, Chang, Wayne, Zheng, Weiyi, Zhou, Wenda, Manassra, Wesam, Sheu, Will, Zaremba, Wojciech, Patil, Yash, Qian, Yilei, Kim, Yongjik, Cheng, Youlong, Zhang, Yu, He, Yuchen, Zhang, Yuchen, Jin, Yujia, Dai, Yunxing, and Malkov, Yury
Subjects: Computer Science - Computation and Language, Computer Science - Artificial Intelligence, Computer Science - Computer Vision and Pattern Recognition, Computer Science - Computers and Society, Computer Science - Machine Learning, Computer Science - Sound, Electrical Engineering and Systems Science - Audio and Speech Processing
Abstract: GPT-4o is an autoregressive omni model that accepts as input any combination of text, audio, image, and video, and generates any combination of text, audio, and image outputs. It's trained end-to-end across text, vision, and audio, meaning all inputs and outputs are processed by the same neural network. GPT-4o can respond to audio inputs in as little as 232 milliseconds, with an average of 320 milliseconds, which is similar to human response time in conversation. It matches GPT-4 Turbo performance on text in English and code, with significant improvement on text in non-English languages, while also being much faster and 50\% cheaper in the API. GPT-4o is especially better at vision and audio understanding compared to existing models. In line with our commitment to building AI safely and consistent with our voluntary commitments to the White House, we are sharing the GPT-4o System Card, which includes our Preparedness Framework evaluations. In this System Card, we provide a detailed look at GPT-4o's capabilities, limitations, and safety evaluations across multiple categories, focusing on speech-to-speech while also evaluating text and image capabilities, and measures we've implemented to ensure the model is safe and aligned. We also include third-party assessments on dangerous capabilities, as well as discussion of potential societal impacts of GPT-4o's text and vision capabilities.
Published: 2024

13. Architecture of TOI-561 planetary system

Author: Piotto, G., Zingales, T., Borsato, L., Egger, J. A., Correia, A. C. M., Simon, A. E., Florén, H. G., Sousa, S. G., Maxted, P. F. L., Nardiello, D., Malavolta, L., Wilson, T. G., Alibert, Y., Adibekyan, V., Bonfanti, A., Luque, R., Santos, N. C., Hooton, M. J., Fossati, L., Smith, A. M. S., Salmon, S., Lacedelli, G., Alonso, R., Bárczy, T., Navascues, D. Barrado, Barros, S. C. C., Baumjohann, W., Beck, T., Benz, W., Billot, N., Brandeker, A., Broeg, C., Buder, M., Cameron, A. Collier, Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Demangeon, O. D. S., Demory, B. O., Derekas, A., Edwards, B., Ehrenreich, D., Erikson, A., Fortier, A., Fridlund, M., Gandolfi, D., Gazeas, K., Gillon, M., Güdel, M., Günther, M. N., Heitzmann, A., Helling, Ch., Isaak, K. G., Kiss, L. L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Lendl, M., Leonardi, P., Magrin, D., Mantovan, G., Mordasini, C., Nascimbeni, V., Olofsson, G., Ottensamer, R., Pagano, I., Pallé, E., Peter, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Ratti, F., Rauer, H., Ribas, I., Scandariato, G., Ségransan, D., Sicilia, D., Stalport, M., Sulis, S., Szabó, Gy. M., Udry, S., Ulmer-Moll, S., Van Grootel, V., Venturini, J., Villaver, E., Walton, N. A., Winn, J. N., and Wolf, S.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: We present new observations from CHEOPS and TESS to clarify the architecture of the planetary system hosted by the old Galactic thick disk star TOI-561. Our global analysis, which also includes previously published photometric and radial velocity data, incontrovertibly proves that TOI-561 is hosting at least four transiting planets with periods of 0.44 days (TOI-561 b), 10.8 days (TOI-561 c), 25.7 days (TOI-561 d), and 77.1 days (TOI-561 e) and a fifth non-transiting candidate, TOI-561f with a period of 433 days. The precise characterisation of TOI-561's orbital architecture is interesting since old and metal-poor thick disk stars are less likely to host ultra-short period Super-Earths like TOI-561 b. The new period of planet -e is consistent with the value obtained using radial velocity alone and is now known to be $77.14399\pm0.00025$ days, thanks to the new CHEOPS and TESS transits. The new data allowed us to improve its radius ($R_p = 2.517 \pm 0.045 R_{\oplus}$ from 5$\%$ to 2$\%$ precision) and mass ($M_p = 12.4 \pm 1.4 M_{\oplus}$) estimates, implying a density of $\rho_p = 0.778 \pm 0.097 \rho_{\oplus}$. Thanks to recent TESS observations and the focused CHEOPS visit of the transit of TOI-561 e, a good candidate for exomoon searches, the planet's period is finally constrained, allowing us to predict transit times through 2030 with 20-minute accuracy. We present an updated version of the internal structure of the four transiting planets. We finally performed a detailed stability analysis, which confirmed the long-term stability of the outer planet TOI-561 f., Comment: 13 pages, 10 Figures. Accepted on MNRAS. Updated the author list
Published: 2024

14. Nonexistence of finite-dimensional estimation algebras on closed smooth manifolds

Author: Kang, Jiayi, Salmon, Andrew, and Yau, Stephen Shing-Toung
Subjects: Mathematics - Optimization and Control, Mathematics - Probability, 93E11, 60G35
Abstract: Estimation algebras have been extensively studied in Euclidean space, where finite-dimensional estimation algebras form the foundation of the Kalman and Benes filters, and have contributed to the discovery of many other finite-dimensional filters. This work extends the theory of estimation algebras to filtering problems on Riemannian manifolds in continuous time. Our main result demonstrates that, with non-constant observation functions, the estimation algebra associated with the system on closed Riemannian manifolds is infinite-dimensional., Comment: 6 pages, submitted to IEEE Transaction on Automatic Control
Published: 2024

15. Identifying a severity measure for head acceleration events associated with suspected concussions

Author: Tierney, Gregory, Tucker, Ross, Tooby, James, Starling, Lindsay, Falvey, Eanna, Salmon, Danielle, Brown, James, Hudson, Sam, Stokes, Keith, Jones, Ben, Kemp, Simon, OHalloran, Patrick, Cross, Matt, Bussey, Melanie, and Allan, David
Subjects: Physics - Medical Physics
Abstract: Objectives: To identify a head acceleration event (HAE) severity measure associated with HIA1 removals in elite level rugby union. Methods: HAEs were recorded from 215 men and 325 women with 30 and 28 HIA1 removals from men and women, respectively. Logistical regression were calculated to identify if peak power, maximum principal strain (MPS) and or Head Acceleration Response Metric (HARM) were associated with HIA1 events compared to non-cases. Optimal threshold values were determined using the Youden Index. Area under the curve (AUC) were compared using a paired sample approach. Significant differences were set at p<0.05. Results: All three severity measures were associated with HIA1 removals in both the mens and womens game. Power performed greatest for HIA1 removals in both the mens and womens games, based on overall AUC, sensitivity, and specificity values. HARM and MPS were found to perform lower than PLA in the womens game based on AUC comparisons (p=0.006 and 0.001, respectively), with MPS performing lower than PAA (p=0.001). Conclusion: The findings progress our understanding of HAE measures associated with HIA1 removals. Peak power, a measure based on fundamental mechanics and commonly used in sports performance, may be a suitable HAE severity measure., Comment: 4 Tables, 2 Figures
Published: 2024

16. Opportunities and challenges of mRNA technologies in development of Dengue Virus Vaccine

Author: Liu, Xiaoyang and Salmon, Daniel
Subjects: Quantitative Biology - Other Quantitative Biology
Abstract: Dengue virus (DENV) is a mosquito-borne virus with a significant human health concern. With 390 million infections annually and 96 million showing clinical symptoms, severe dengue can lead to life-threatening conditions like dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). The only FDA-approved vaccine, Dengvaxia, has limitations due to antibody-dependent enhancement (ADE), necessitating careful administration. The recent pre-approval of TAK-003 by WHO in 2024 highlights ongoing efforts to improve vaccine options. This review explores recent advancements in dengue vaccine development, emphasizing potential utility of mRNA-based vaccines. By examining current clinical trial data and innovations, we aim to identify promising strategies to address the limitations of existing vaccines and enhance global dengue prevention efforts., Comment: 16 pages, 1 figure, 1 table
Published: 2024

17. Comparing the Efficiency of General State Space Reversible MCMC Algorithms

Author: Salmon, Geoffrey T. and Rosenthal, Jeffrey S.
Subjects: Mathematics - Probability, 60J05
Abstract: We review and provide new proofs of results used to compare the efficiency of estimates generated by reversible MCMC algorithms on a general state space. We provide a full proof of the formula for the asymptotic variance for real-valued functionals on $\phi$-irreducible reversible Markov chains, first introduced by Kipnis and Varadhan. Given two Markov kernels $P$ and $Q$ with stationary measure $\pi$, we say that the Markov kernel $P$ efficiency dominates the Markov kernel $Q$ if the asymptotic variance with respect to $P$ is at most the asymptotic variance with respect to $Q$ for every real-valued functional $f\in L^2(\pi)$. Assuming only a basic background in functional analysis, we prove that for two $\phi$-irreducible reversible Markov kernels $P$ and $Q$, $P$ efficiency dominates $Q$ if and only if the operator $Q-P$, where $P$ is the operator on $L^2(\pi)$ that maps $f\mapsto\int f(y)P(\cdot,dy)$ and similarly for $Q$, is positive on $L^2(\pi)$, i.e. $\langle f,(Q-P)f\rangle\geq0$ for every $f\in L^2(\pi)$. We use this result to show that reversible antithetic kernels are more efficient than i.i.d. sampling, and that efficiency dominance is a partial ordering on $\phi$-irreducible reversible Markov kernels. We also provide a proof based on that of Tierney that Peskun dominance is a sufficient condition for efficiency dominance for reversible kernels. Using these results, we show that Markov kernels formed by randomly selecting other "component" Markov kernels will always efficiency dominate another Markov kernel formed in this way, as long as the component kernels of the former efficiency dominate those of the latter. These results on the efficiency dominance of combining component kernels generalises the results on the efficiency dominance of combined chains introduced by Neal and Rosenthal from finite state spaces to general state spaces., Comment: 27 pages
Published: 2024

18. Exact planetary waves and jet streams

Author: Pizzo, Nick and Salmon, Rick
Subjects: Physics - Fluid Dynamics
Abstract: We investigate exact nonlinear waves on surfaces locally approximating the rotating sphere for two-dimensional inviscid incompressible flow. Our first system corresponds to a beta-plane approximation at the equator and the second to a gamma approximation, with the latter describing flow near the poles. We find exact wave solutions in the Lagrangian reference frame that cannot be written down in closed form in the Eulerian reference frame. The wave particle trajectories, contours of potential vorticity and Lagrangian mean velocity take relatively simple forms. The waves possess a non-trivial Lagrangian mean flow that depends on the amplitude of the waves and on a particle label that characterizes values of constant potential vorticity. The mean flow arises due to potential vorticity conservation on fluid particles. Solutions over the entire space are generated by assuming that the flow far from the origin is zonal and there is a region of constant potential vorticity between this zonal flow and the waves. In the gamma approximation a class of waves are found which, based on analogous solutions on the plane, we call Ptolemaic vortex waves. The mean flow of some of these waves resemble polar jet streams. Several illustrative solutions are used as initial conditions in the fully spherical rotating Navier-Stokes equations, where integration is performed via the numerical scheme presented in Salmon and Pizzo (2023). The potential vorticity contours found from these numerical experiments vary between stable permanent progressive form and fully turbulent flows generated by wave breaking.
Published: 2024
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19. A Decomposition of Interaction Force for Multi-Agent Co-Manipulation

Author: Shaw, Kody B., Cordon, Dallin L., Killpack, Marc D., and Salmon, John L.
Subjects: Computer Science - Robotics, Electrical Engineering and Systems Science - Signal Processing
Abstract: Multi-agent human-robot co-manipulation is a poorly understood process with many inputs that potentially affect agent behavior. This paper explores one such input known as interaction force. Interaction force is potentially a primary component in communication that occurs during co-manipulation. There are, however, many different perspectives and definitions of interaction force in the literature. Therefore, a decomposition of interaction force is proposed that provides a consistent way of ascertaining the state of an agent relative to the group for multi-agent co-manipulation. This proposed method extends a current definition from one to four degrees of freedom, does not rely on a predefined object path, and is independent of the number of agents acting on the system and their locations and input wrenches (forces and torques). In addition, all of the necessary measures can be obtained by a self-contained robotic system, allowing for a more flexible and adaptive approach for future co-manipulation robot controllers., Comment: 11 pages, 19 figures, 4 tables, 3 equations, prepared for submission to transactions on haptics
Published: 2024

20. Bridging Education Gaps: Implementation of Mavis Talking Pens and Books in Non-Formal Learning Centers in Northeast Nigeria

Author: Marlana Salmon-Letelier, Bernard Thuo, Allison Park, Gabriel Sambo, and Richard Stephen Tekdek
Abstract: The educational crisis in Northeast Nigeria, deepened by conflict, economic challenges, and the COVID-19 pandemic, has significantly hindered access to quality education for millions of children. In response, EdTech solutions such as the Mavis Talking Books and Pens have shown potential in supporting education in conflict-affected and under-resourced areas. This study examines the implementation of the Mavis Talking Books and Pens within non-formal classrooms in Borno state, focusing on out-of-school children aged 9 to 16 who are part of an ongoing non-formal learning initiative. The research aimed to assess the effectiveness of the Mavis tools and identify the conditions necessary for their successful implementation and scalability using a mixed-methods approach involving surveys, focus groups, interviews, and observations with 70 learning facilitators and 350 students across 70 non-formal learning centers. The study found that the Mavis Talking Books and Pens were largely effectively implemented, which appears to lead to student progress, although some inconsistencies in student engagement and classroom management were noted. Challenges included the need for more frequent use, better student-to-pen ratios, and improvements in the learning environment. Facilitators also highlighted the importance of stronger community engagement and addressing external factors affecting student attendance. To overcome these challenges, the study suggests focusing on strengthening support systems, optimizing resource allocation, and enhancing community engagement. These findings offer important insights into how EdTech tools like Mavis Talking Books and Pens can be effectively integrated into non-formal education settings in crisis-affected regions, helping to improve educational outcomes for marginalized children in similar contexts.
Published: 2024

21. Skills Mismatch or Skills Mishmash? Problem Representation in England's Lifelong Loan Entitlement Policy

Author: Michael Salmon
Abstract: The valorization of skills in English higher education policy-making is a long-standing refrain, informing both rhetoric and investment from government and shaping university behaviour. Critiques of the 'skills agenda' are equally established, on grounds of its contested evidence base, manner of implementation and even its very definition. This paper draws on Bacchi's 'What is the Problem Represented to Be?' (WPR) approach (Bacchi, in: Bletsas, Beasley (eds) Engaging with Carol Bacchi: strategic interventions and exchanges, The University of Adelaide Press, Adelaide, 2021a; Bacchi and Goodwin in Poststructural policy analysis: a guide to practice, Palgrave Macmillan, New York, 2016) to examine how the UK Department for Education's nascent Lifelong Loan Entitlement (LLE) policy represents, and therefore in Bacchi's sense produces, problems in the English tertiary education system. Through its WPR analysis of a significant contemporary shift in the English funding system, this paper demonstrates how the LLE policy replicates but also extends certain key features of the skills agenda and the dominant presuppositions of current English higher education policy-making.
Published: 2024
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22. Medical Home, Developmental Monitoring/Screening, and Early Autism Identification

Author: Brian Barger, Ashley Salmon, and Quentin Moore
Abstract: Developmental monitoring/screening predict early identified autism spectrum disorders (ASD), but studies have not yet robustly controlled for a key health care service impacting early identification: medical home. National Surveys of Children's Health (NSCH; 2016-2020) were used to determine the relationship between medical home, developmental monitoring/screening, and identified ASD. NSCH overall medical home variable had a minimal relationship with ASD (under 5 years of age, under 5 identified in last year, under 5 identified over a year prior). Usual source of care was positively, and care coordination negatively, associated with ASD identified in last year, suggesting the overall medical home variable may mask variance from subscales. Research is needed to determine how medical home relates to identification in applied settings.
Published: 2024
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23. Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin

Author: Miller, Richard A, Harrison, David E, Cortopassi, Gino A, Dehghan, Ishmael, Fernandez, Elizabeth, Garratt, Michael, Geisler, John G, Ginsburg, Brett C, Han, Melissa L, Kaczorowski, Catherine C, Kumar, Navasuja, Leiser, Scott F, Lopez-Cruzan, Marisa, Milne, Ginger, Mitchell, James R, Nelson, James F, Reifsnyder, Peter C, Salmon, Adam B, Korstanje, Ron, Rosenthal, Nadia, and Strong, Randy
Subjects: Biomedical and Clinical Sciences, Clinical Sciences, Women's Health, Aging, Animals, Canagliflozin, Male, Female, Thiosulfates, Longevity, Mice, Sodium-Glucose Transporter 2 Inhibitors, Sex Factors, Alpha-ketoglutarate, SGLT2 inhibitor Canagliflozin, Lifespan, Genetics, Clinical sciences
Abstract: Genetically heterogeneous UM-HET3 mice born in 2020 were used to test possible lifespan effects of alpha-ketoglutarate (AKG), 2,4-dinitrophenol (DNP), hydralazine (HYD), nebivolol (NEBI), 16α-hydroxyestriol (OH_Est), and sodium thiosulfate (THIO), and to evaluate the effects of canagliflozin (Cana) when started at 16 months of age. OH_Est produced a 15% increase (p = 0.0001) in median lifespan in males but led to a significant (7%) decline in female lifespan. Cana, started at 16 months, also led to a significant increase (14%, p = 0.004) in males and a significant decline (6%, p = 0.03) in females. Cana given to mice at 6 months led, as in our previous study, to an increase in male lifespan without any change in female lifespan, suggesting that this agent may lead to female-specific late-life harm. We found that blood levels of Cana were approximately 20-fold higher in aged females than in young males, suggesting a possible mechanism for the sex-specific disparities in its effects. NEBI was also found to produce a female-specific decline (4%, p = 0.03) in lifespan. None of the other tested drugs provided a lifespan benefit in either sex. These data bring to 7 the list of ITP-tested drugs that induce at least a 10% lifespan increase in one or both sexes, add a fourth drug with demonstrated mid-life benefits on lifespan, and provide a testable hypothesis that might explain the sexual dimorphism in lifespan effects of the SGLT2 inhibitor Cana.
Published: 2024

24. Large Divergence of Projected High Latitude Vegetation Composition and Productivity Due To Functional Trait Uncertainty

Author: Liu, Yanlan, Holm, Jennifer A, Koven, Charles D, Salmon, Verity G, Rogers, Alistair, and Torn, Margaret S
Subjects: Hydrology, Climate Change Science, Earth Sciences, Climate Action, dynamic vegetation modeling, Arctic vegetation change, plant trait, vegetation demography, uncertainty analysis, Atmospheric Sciences, Physical Geography and Environmental Geoscience, Environmental Science and Management, Climate change science
Abstract: Vegetation distribution and composition are expected to change in northern high latitudes under rapid warming, which regulates ecosystem functions but remains challenging to predict. Vegetation change arises from the interplay of chronic climate trends such as warming and transient demographic processes of recruitment, growth, competition, and mortality. Most predictive models overlooked the role of demographic dynamics controlled by plant traits. Here, we simulate vegetation dynamics at the Kougarok Hillslope site in Alaska under historical and future climates using the E3SM Land Model coupled to the Functionally Assembled Terrestrial Simulator (ELM-FATES). To evaluate the roles of plant traits, we parameterize the model with 5,265 trait configurations representing diverse physiological and demographic strategies. Results show current modeled biomass, composition, and productivity are most sensitive to traits controlling photosynthetic capacity, carbon allocation, allometry, and phenology. Among all trait configurations, ∼5% reproduce in situ biomass and plant functional type (PFT) composition measured in 2016, that are indistinguishable from these two observed ecosystem states. Notably, these same trait configurations produce diverging biomass, composition, and productivity under future climate, where the uncertainty attributable to traits is twice the change attributable to climate change. The variation of projected productivity arises from emerging PFT composition under novel climate regimes, primarily explained by traits controlling cold-induced mortality, recruitment, and allometry. Our findings highlight the importance and uncertainty of demographic dynamics and its interaction with climate change in shaping Arctic vegetation change. Improved model predictions will likely benefit from explicit consideration of vegetation demography and better constraints of critical traits.
Published: 2024

25. TOI-757 b: an eccentric transiting mini-Neptune on a 17.5-d orbit

Author: Alqasim, A., Grieves, N., Rosário, N. M., Gandolfi, D., Livingston, J. H., Sousa, S., Collins, K. A., Teske, J. K., Fridlund, M., Egger, J. A., Cabrera, J., Hellier, C., Lanza, A. F., Van Eylen, V., Bouchy, F., Oelkers, R. J., Srdoc, G., Shectman, S., Günther, M., Goffo, E., Wilson, T., Serrano, L. M., Brandeker, A., Wang, S. X., Heitzmann, A., Bonfanti, A., Fossati, L., Alibert, Y., Delrez, L., Sefako, R., Barros, S., Collins, K. I., Demangeon, O. D. S., Albrecht, S. H., Alonso, R., Asquier, J., Barczy, T., Barrado, D., Baumjohann, W., Beck, T., Benz, W., Billot, N., Borsato, L., Broeg, C., Bryant, E. M., Butler, R. P., Cochran, W. D., Cameron, A. Collier, Correia, A. C. M., Crane, J. D., Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Daylan, T., Deleuil, M., Deline, A., Demory, B. -O., Derekas, A., Edwards, B., Ehrenreich, D., Erikson, A., Essack, Z., Fortier, A., Gazeas, K., Gillon, M., Gudel, M., Hasiba, J., Hatzes, A. P., Helling, Ch., Hirano, T., Howell, S. B., Hoyer, S., Isaak, K. G., Jenkins, J. M., Kanodia, S., Kiss, L. L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Lendl, M., Lund, M. B., Luque, R., Mann, A. W., Magrin, D., Maxted, P. F. L., Mordasini, C., Narita, N., Nascimbeni, V., Nowak, G., Olofsson, G., Osborn, H. P., Osborne, H. L. M., Osip, D., Ottensamer, R., Pagano, I., Palle, E., Peter, G., Piotto, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Rauer, H., Redfield, S., Ribas, I., Rice, M., Ricker, G. R., Rieder, M., Salmon, S., Santos, N. C., Scandariato, G., Seager, S., Segransan, D., Shporer, A., Simon, A. E., Smith, A. M. S., Stalport, M., Szabo, Gy. M., Thompson, I., Twicken, J. D., Udry, S., Vanderspek, R., Van Grootel, V., Venturini, J., Villaver, E., Villaseñor, J., Viotto, V., Walter, I., Walton, N. A., Winn, J. N., and Yee, S. W.
Subjects: Astrophysics - Earth and Planetary Astrophysics
Abstract: We report the spectroscopic confirmation and fundamental properties of TOI-757 b, a mini-Neptune on a 17.5-day orbit transiting a bright star ($V = 9.7$ mag) discovered by the TESS mission. We acquired high-precision radial velocity measurements with the HARPS, ESPRESSO, and PFS spectrographs to confirm the planet detection and determine its mass. We also acquired space-borne transit photometry with the CHEOPS space telescope to place stronger constraints on the planet radius, supported with ground-based LCOGT photometry. WASP and KELT photometry were used to help constrain the stellar rotation period. We also determined the fundamental parameters of the host star. We find that TOI-757 b has a radius of $R_{\mathrm{p}} = 2.5 \pm 0.1 R_{\oplus}$ and a mass of $M_{\mathrm{p}} = 10.5^{+2.2}_{-2.1} M_{\oplus}$, implying a bulk density of $\rho_{\text{p}} = 3.6 \pm 0.8$ g cm$^{-3}$. Our internal composition modeling was unable to constrain the composition of TOI-757 b, highlighting the importance of atmospheric observations for the system. We also find the planet to be highly eccentric with $e$ = 0.39$^{+0.08}_{-0.07}$, making it one of the very few highly eccentric planets among precisely characterized mini-Neptunes. Based on comparisons to other similar eccentric systems, we find a likely scenario for TOI-757 b's formation to be high eccentricity migration due to a distant outer companion. We additionally propose the possibility of a more intrinsic explanation for the high eccentricity due to star-star interactions during the earlier epoch of the Galactic disk formation, given the low metallicity and older age of TOI-757., Comment: Accepted for publication in MNRAS; 26 pages, 14 figures, 6 tables
Published: 2024

26. A review of handcrafted and deep radiomics in neurological diseases: transitioning from oncology to clinical neuroimaging

Author: Lavrova, Elizaveta, Woodruff, Henry C., Khan, Hamza, Salmon, Eric, Lambin, Philippe, and Phillips, Christophe
Subjects: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Artificial Intelligence, Quantitative Biology - Quantitative Methods
Abstract: Medical imaging technologies have undergone extensive development, enabling non-invasive visualization of clinical information. The traditional review of medical images by clinicians remains subjective, time-consuming, and prone to human error. With the recent availability of medical imaging data, quantification have become important goals in the field. Radiomics, a methodology aimed at extracting quantitative information from imaging data, has emerged as a promising approach to uncover hidden biological information and support decision-making in clinical practice. This paper presents a review of the radiomic pipeline from the clinical neuroimaging perspective, providing a detailed overview of each step with practical advice. It discusses the application of handcrafted and deep radiomics in neuroimaging, stratified by neurological diagnosis. Although radiomics shows great potential for increasing diagnostic precision and improving treatment quality in neurology, several limitations hinder its clinical implementation. Addressing these challenges requires collaborative efforts, advancements in image harmonization methods, and the establishment of reproducible and standardized pipelines with transparent reporting. By overcoming these obstacles, radiomics can significantly impact clinical neurology and enhance patient care.
Published: 2024

27. Characterisation of the Warm-Jupiter TOI-1130 system with CHEOPS and photo-dynamical approach

Author: Borsato, L., Degen, D., Leleu, A., Hooton, M. J., Egger, J. A., Bekkelien, A., Brandeker, A., Cameron, A. Collier, Günther, M. N., Nascimbeni, V., Persson, C. M., Bonfanti, A., Wilson, T. G., Correia, A. C. M., Zingales, T., Guillot, T., Triaud, A. H. M. J., Piotto, G., Gandolfi, D., Abe, L., Alibert, Y., Alonso, R., Bárczy, T., Navascues, D. Barrado, Barros, S. C. C., Baumjohann, W., Beck, T., Bendjoya, P., Benz, W., Billot, N., Broeg, C., Busch, M. -D., Csizmadia, Sz., Cubillos, P. E., Davies, M. B., Deleuil, M., Deline, A., Delrez, L., Demangeon, O. D. S., Demory, B. -O., Derekas, A., Edwards, B., Ehrenreich, D., Erikson, A., Fortier, A., Fossati, L., Fridlund, M., Gazeas, K., Gillon, M., Güdel, M., Heitzmann, A., Helling, Ch., Hoyer, S., Isaak, K. G., Kiss, L. L., Korth, J., Lam, K. W. F., Laskar, J., Etangs, A. Lecavelier des, Lendl, M., Magrin, D., Marafatto, L., Maxted, P. F. L., Mecina, M., Mékarnia, D., Mordasini, C., Mura, D., Olofsson, G., Ottensamer, R., Pagano, I., Pallé, E., Peter, G., Pollacco, D., Queloz, D., Ragazzoni, R., Rando, N., Ratti, F., Rauer, H., Ribas, I., Salmon, S., Santos, N. C., Scandariato, G., Ségransan, D., Simon, A. E., Smith, A. M. S., Sousa, S. G., Stalport, M., Suarez, O., Sulis, S., Szabó, Gy. M., Udry, S., Van Grootel, V., Venturini, J., Villaver, E., Walton, N. A., and Wolter, D.
Subjects: Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: Among the thousands of exoplanets discovered to date, approximately a few hundred gas giants on short-period orbits are classified as "lonely" and only a few are in a multi-planet system with a smaller companion on a close orbit. The processes that formed multi-planet systems hosting gas giants on close orbits are poorly understood, and only a few examples of this kind of system have been observed and well characterised. Within the contest of multi-planet system hosting gas-giant on short orbits, we characterise TOI-1130 system by measuring masses and orbital parameters. This is a 2-transiting planet system with a Jupiter-like planet (c) on a 8.35 days orbit and a Neptune-like planet (b) on an inner (4.07 days) orbit. Both planets show strong anti-correlated transit timing variations (TTVs). Furthermore, radial velocity (RV) analysis showed an additional linear trend, a possible hint of a non-transiting candidate planet on a far outer orbit. Since 2019, extensive transit and radial velocity observations of the TOI-1130 have been acquired using TESS and various ground-based facilities. We present a new photo-dynamical analysis of all available transit and RV data, with the addition of new CHEOPS and ASTEP+ data that achieve the best precision to date on the planetary radii and masses and on the timings of each transit. We were able to model interior structure of planet b constraining the presence of a gaseous envelope of H/He, while it was not possible to assess the possible water content. Furthermore, we analysed the resonant state of the two transiting planets, and we found that they lie just outside the resonant region. This could be the result of the tidal evolution that the system underwent. We obtained both masses of the planets with a precision less than 1.5%, and radii with a precision of about 1% and 3% for planet b and c, respectively., Comment: 22 pages, 10 figures, Accepted for publication by Astronomy and Astrophysics
Published: 2024
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28. The PLATO Mission

Author: Rauer, Heike, Aerts, Conny, Cabrera, Juan, Deleuil, Magali, Erikson, Anders, Gizon, Laurent, Goupil, Mariejo, Heras, Ana, Lorenzo-Alvarez, Jose, Marliani, Filippo, Martin-Garcia, César, Mas-Hesse, J. Miguel, O'Rourke, Laurence, Osborn, Hugh, Pagano, Isabella, Piotto, Giampaolo, Pollacco, Don, Ragazzoni, Roberto, Ramsay, Gavin, Udry, Stéphane, Appourchaux, Thierry, Benz, Willy, Brandeker, Alexis, Güdel, Manuel, Janot-Pacheco, Eduardo, Kabath, Petr, Kjeldsen, Hans, Min, Michiel, Santos, Nuno, Smith, Alan, Suarez, Juan-Carlos, Werner, Stephanie C., Aboudan, Alessio, Abreu, Manuel, a, Lorena Acu, Adams, Moritz, Adibekyan, Vardan, Affer, Laura, Agneray, François, Agnor, Craig, Børsen-Koch, Victor Aguirre, Ahmed, Saad, Aigrain, Suzanne, Al-Bahlawan, Ashraf, Gil, M de los Angeles Alcacera, Alei, Eleonora, Alencar, Silvia, Alexander, Richard, Alfonso-Garzón, Julia, Alibert, Yann, Prieto, Carlos Allende, Almeida, Leonardo, Sobrino, Roi Alonso, Altavilla, Giuseppe, Althaus, Christian, Trujillo, Luis Alonso Alvarez, Amarsi, Anish, Eiff, Matthias Ammler-von, Amôres, Eduardo, Andrade, Laerte, Antoniadis-Karnavas, Alexandros, António, Carlos, del Moral, Beatriz Aparicio, Appolloni, Matteo, Arena, Claudio, Armstrong, David, Aliaga, Jose Aroca, Asplund, Martin, Audenaert, Jeroen, Auricchio, Natalia, Avelino, Pedro, Baeke, Ann, Baillié, Kevin, Balado, Ana, Balagueró, Pau Ballber, Balestra, Andrea, Ball, Warrick, Ballans, Herve, Ballot, Jerome, Barban, Caroline, Barbary, Gaële, Barbieri, Mauro, Forteza, Sebasti Barceló, Barker, Adrian, Barklem, Paul, Barnes, Sydney, Navascues, David Barrado, Barragan, Oscar, Baruteau, Clément, Basu, Sarbani, Baudin, Frederic, Baumeister, Philipp, Bayliss, Daniel, Bazot, Michael, Beck, Paul G., Bedding, Tim, Belkacem, Kevin, Bellinger, Earl, Benatti, Serena, Benomar, Othman, Bérard, Diane, Bergemann, Maria, Bergomi, Maria, Bernardo, Pierre, Biazzo, Katia, Bignamini, Andrea, Bigot, Lionel, Billot, Nicolas, Binet, Martin, Biondi, David, Biondi, Federico, Birch, Aaron C., Bitsch, Bertram, Ceballos, Paz Victoria Bluhm, Bódi, Attila, Bognár, Zsófia, Boisse, Isabelle, Bolmont, Emeline, Bonanno, Alfio, Bonavita, Mariangela, Bonfanti, Andrea, Bonfils, Xavier, Bonito, Rosaria, Bonomo, Aldo Stefano, Börner, Anko, Saikia, Sudeshna Boro, Martín, Elisa Borreguero, Borsa, Francesco, Borsato, Luca, Bossini, Diego, Bouchy, Francois, Boué, Gwenaël, Boufleur, Rodrigo, Boumier, Patrick, Bourrier, Vincent, Bowman, Dominic M., Bozzo, Enrico, Bradley, Louisa, Bray, John, Bressan, Alessandro, Breton, Sylvain, Brienza, Daniele, Brito, Ana, Brogi, Matteo, Brown, Beverly, Brown, David J. A., Brun, Allan Sacha, Bruno, Giovanni, Bruns, Michael, Buchhave, Lars A., Bugnet, Lisa, Buldgen, Gaël, Burgess, Patrick, Busatta, Andrea, Busso, Giorgia, Buzasi, Derek, Caballero, José A., Cabral, Alexandre, Gomez, Juan-Francisco Cabrero, Calderone, Flavia, Cameron, Robert, Cameron, Andrew, Campante, Tiago, Gestal, Néstor Campos, Martins, Bruno Leonardo Canto, Cara, Christophe, Carone, Ludmila, Carrasco, Josep Manel, Casagrande, Luca, Casewell, Sarah L., Cassisi, Santi, Castellani, Marco, Castro, Matthieu, Catala, Claude, Fernández, Irene Catalán, Catelan, Márcio, Cegla, Heather, Cerruti, Chiara, Cessa, Virginie, Chadid, Merieme, Chaplin, William, Charpinet, Stephane, Chiappini, Cristina, Chiarucci, Simone, Chiavassa, Andrea, Chinellato, Simonetta, Chirulli, Giovanni, Christensen-Dalsgaard, Jørgen, Church, Ross, Claret, Antonio, Clarke, Cathie, Claudi, Riccardo, Clermont, Lionel, Coelho, Hugo, Coelho, Joao, Cogato, Fabrizio, Colomé, Josep, Condamin, Mathieu, García, Fernando Conde, Conseil, Simon, Corbard, Thierry, Correia, Alexandre C. M., Corsaro, Enrico, Cosentino, Rosario, Costes, Jean, Cottinelli, Andrea, Covone, Giovanni, Creevey, Orlagh L., Crida, Aurelien, Csizmadia, Szilard, Cunha, Margarida, Curry, Patrick, da Costa, Jefferson, da Silva, Francys, Dalal, Shweta, Damasso, Mario, Damiani, Cilia, Damiani, Francesco, Chagas, Maria Liduina das, Davies, Melvyn, Davies, Guy, Davies, Ben, Davison, Gary, de Almeida, Leandro, de Angeli, Francesca, de Barros, Susana Cristina Cabral, Leão, Izan de Castro, de Freitas, Daniel Brito, de Freitas, Marcia Cristina, De Martino, Domitilla, de Medeiros, José Renan, de Paula, Luiz Alberto, Gómez, Álvaro de Pedraza, de Plaa, Jelle, De Ridder, Joris, Deal, Morgan, Decin, Leen, Deeg, Hans, Innocenti, Scilla Degl, Deheuvels, Sebastien, del Burgo, Carlos, Del Sordo, Fabio, Delgado-Mena, Elisa, Demangeon, Olivier, Denk, Tilmann, Derekas, Aliz, Desert, Jean-Michel, Desidera, Silvano, Dexet, Marc, Di Criscienzo, Marcella, Di Giorgio, Anna Maria, Di Mauro, Maria Pia, Rial, Federico Jose Diaz, Díaz-García, José-Javier, Dima, Marco, Dinuzzi, Giacomo, Dionatos, Odysseas, Distefano, Elisa, Nascimento Jr., Jose-Dias do, Domingo, Albert, D'Orazi, Valentina, Dorn, Caroline, Doyle, Lauren, Duarte, Elena, Ducellier, Florent, Dumaye, Luc, Dumusque, Xavier, Dupret, Marc-Antoine, Eggenberger, Patrick, Ehrenreich, David, Eigmüller, Philipp, Eising, Johannes, Emilio, Marcelo, Eriksson, Kjell, Ermocida, Marco, Giribaldi, Riano Isidoro Escate, Eschen, Yoshi, ez, Lucía Espinosa Yá, Estrela, In s, Evans, Dafydd Wyn, Fabbian, Damian, Fabrizio, Michele, Faria, João Pedro, Farina, Maria, Farinato, Jacopo, Feliz, Dax, Feltzing, Sofia, Fenouillet, Thomas, Fernández, Miguel, Ferrari, Lorenza, Ferraz-Mello, Sylvio, Fialho, Fabio, Fienga, Agnes, Figueira, Pedro, Fiori, Laura, Flaccomio, Ettore, Focardi, Mauro, Foley, Steve, Fontignie, Jean, Ford, Dominic, Fornazier, Karin, Forveille, Thierry, Fossati, Luca, Franca, Rodrigo de Marca, da Silva, Lucas Franco, Frasca, Antonio, Fridlund, Malcolm, Furlan, Marco, Gabler, Sarah-Maria, Gaido, Marco, Gallagher, Andrew, Sempere, Paloma I. Gallego, Galli, Emanuele, García, Rafael A., Hernández, Antonio García, Munoz, Antonio Garcia, García-Vázquez, Hugo, Haba, Rafael Garrido, Gaulme, Patrick, Gauthier, Nicolas, Gehan, Charlotte, Gent, Matthew, Georgieva, Iskra, Ghigo, Mauro, Giana, Edoardo, Gill, Samuel, Girardi, Leo, Winter, Silvia Giuliatti, Giusi, Giovanni, da Silva, João Gomes, Zazo, Luis Jorge Gómez, Gomez-Lopez, Juan Manuel, Hernández, Jonay Isai González, Murillo, Kevin Gonzalez, Melchor, Alejandro Gonzalo, Gorius, Nicolas, Gouel, Pierre-Vincent, Goulty, Duncan, Granata, Valentina, Grenfell, John Lee, bach, Denis Grie, Grolleau, Emmanuel, Grouffal, Salomé, Grziwa, Sascha, Guarcello, Mario Giuseppe, Gueguen, Lo c, Guenther, Eike Wolf, Guilhem, Terrasa, Guillerot, Lucas, Guillot, Tristan, Guiot, Pierre, Guterman, Pascal, Gutiérrez, Antonio, Gutiérrez-Canales, Fernando, Hagelberg, Janis, Haldemann, Jonas, Hall, Cassandra, Handberg, Rasmus, Harrison, Ian, Harrison, Diana L., Hasiba, Johann, Haswell, Carole A., Hatalova, Petra, Hatzes, Artie, Haywood, Raphaelle, Hébrard, Guillaume, Heckes, Frank, Heiter, Ulrike, Hekker, Saskia, Heller, René, Helling, Christiane, Helminiak, Krzysztof, Hemsley, Simon, Heng, Kevin, Herbst, Konstantin, Hermans, Aline, Hermes, JJ, Torres, Nadia Hidalgo, Hinkel, Natalie, Hobbs, David, Hodgkin, Simon, Hofmann, Karl, Hojjatpanah, Saeed, Houdek, Günter, Huber, Daniel, Huesler, Joseph, Hui-Bon-Hoa, Alain, Huygen, Rik, Huynh, Duc-Dat, Iro, Nicolas, Irwin, Jonathan, Irwin, Mike, Izidoro, André, Jacquinod, Sophie, Jannsen, Nicholas Emborg, Janson, Markus, Jeszenszky, Harald, Jiang, Chen, Mancebo, Antonio José Jimenez, Jofre, Paula, Johansen, Anders, Johnston, Cole, Jones, Geraint, Kallinger, Thomas, Kálmán, Szilárd, Kanitz, Thomas, Karjalainen, Marie, Karjalainen, Raine, Karoff, Christoffer, Kawaler, Steven, Kawata, Daisuke, Keereman, Arnoud, Keiderling, David, Kennedy, Tom, Kenworthy, Matthew, Kerschbaum, Franz, Kidger, Mark, Kiefer, Flavien, Kintziger, Christian, Kislyakova, Kristina, Kiss, László, Klagyivik, Peter, Klahr, Hubert, Klevas, Jonas, Kochukhov, Oleg, Köhler, Ulrich, Kolb, Ulrich, Koncz, Alexander, Korth, Judith, Kostogryz, Nadiia, Kovács, Gábor, Kovács, József, Kozhura, Oleg, Krivova, Natalie, Kucinskas, Arunas, Kuhlemann, Ilyas, Kupka, Friedrich, Laauwen, Wouter, Labiano, Alvaro, Lagarde, Nadege, Laget, Philippe, Laky, Gunter, Lam, Kristine Wai Fun, Lambrechts, Michiel, Lammer, Helmut, Lanza, Antonino Francesco, Lanzafame, Alessandro, Martiz, Mariel Lares, Laskar, Jacques, Latter, Henrik, Lavanant, Tony, Lawrenson, Alastair, Lazzoni, Cecilia, Lebre, Agnes, Lebreton, Yveline, Etangs, Alain Lecavelier des, Lee, Katherine, Leinhardt, Zoe, Leleu, Adrien, Lendl, Monika, Leto, Giuseppe, Levillain, Yves, Libert, Anne-Sophie, Lichtenberg, Tim, Ligi, Roxanne, Lignieres, Francois, Lillo-Box, Jorge, Linsky, Jeffrey, Liu, John Scige, Loidolt, Dominik, Longval, Yuying, Lopes, Ilídio, Lorenzani, Andrea, Ludwig, Hans-Guenter, Lund, Mikkel, Lundkvist, Mia Sloth, Luri, Xavier, Maceroni, Carla, Madden, Sean, Madhusudhan, Nikku, Maggio, Antonio, Magliano, Christian, Magrin, Demetrio, Mahy, Laurent, Maibaum, Olaf, Malac-Allain, LeeRoy, Malapert, Jean-Christophe, Malavolta, Luca, Maldonado, Jesus, Mamonova, Elena, Manchon, Louis, Manjón, Andres, Mann, Andrew, Mantovan, Giacomo, Marafatto, Luca, Marconi, Marcella, Mardling, Rosemary, Marigo, Paola, Marinoni, Silvia, Marques, rico, Marques, Joao Pedro, Marrese, Paola Maria, Marshall, Douglas, Perales, Silvia Martínez, Mary, David, Marzari, Francesco, Masana, Eduard, Mascher, Andrina, Mathis, Stéphane, Mathur, Savita, Vodopivec, Iris Martín, Figueiredo, Ana Carolina Mattiuci, Maxted, Pierre F. L., Mazeh, Tsevi, Mazevet, Stephane, Mazzei, Francesco, McCormac, James, McMillan, Paul, Menou, Lucas, Merle, Thibault, Meru, Farzana, Mesa, Dino, Messina, Sergio, Mészáros, Szabolcs, Meunier, Nadége, Meunier, Jean-Charles, Micela, Giuseppina, Michaelis, Harald, Michel, Eric, Michielsen, Mathias, Michtchenko, Tatiana, Miglio, Andrea, Miguel, Yamila, Milligan, David, Mirouh, Giovanni, Mitchell, Morgan, Moedas, Nuno, Molendini, Francesca, Molnár, László, Mombarg, Joey, Montalban, Josefina, Montalto, Marco, Monteiro, Mário J. P. F. G., Sánchez, Francisco Montoro, Morales, Juan Carlos, Morales-Calderon, Maria, Morbidelli, Alessandro, Mordasini, Christoph, Moreau, Chrystel, Morel, Thierry, Morello, Guiseppe, Morin, Julien, Mortier, Annelies, Mosser, Beno t, Mourard, Denis, Mousis, Olivier, Moutou, Claire, Mowlavi, Nami, Moya, Andrés, Muehlmann, Prisca, Muirhead, Philip, Munari, Matteo, Musella, Ilaria, Mustill, Alexander James, Nardetto, Nicolas, Nardiello, Domenico, Narita, Norio, Nascimbeni, Valerio, Nash, Anna, Neiner, Coralie, Nelson, Richard P., Nettelmann, Nadine, Nicolini, Gianalfredo, Nielsen, Martin, Niemi, Sami-Matias, Noack, Lena, Noels-Grotsch, Arlette, Noll, Anthony, Norazman, Azib, Norton, Andrew J., Nsamba, Benard, Ofir, Aviv, Ogilvie, Gordon, Olander, Terese, Olivetto, Christian, Olofsson, Göran, Ong, Joel, Ortolani, Sergio, Oshagh, Mahmoudreza, Ottacher, Harald, Ottensamer, Roland, Ouazzani, Rhita-Maria, Paardekooper, Sijme-Jan, Pace, Emanuele, Pajas, Miriam, Palacios, Ana, Palandri, Gaelle, Palle, Enric, Paproth, Carsten, Parro, Vanderlei, Parviainen, Hannu, Granado, Javier Pascual, Passegger, Vera Maria, Pastor-Morales, Carmen, Pätzold, Martin, Pedersen, May Gade, Hidalgo, David Pena, Pepe, Francesco, Pereira, Filipe, Persson, Carina M., Pertenais, Martin, Peter, Gisbert, Petit, Antoine C., Petit, Pascal, Pezzuto, Stefania, Pichierri, Gabriele, Pietrinferni, Adriano, Pinheiro, Fernando, Pinsonneault, Marc, Plachy, Emese, Plasson, Philippe, Plez, Bertrand, Poppenhaeger, Katja, Poretti, Ennio, Portaluri, Elisa, Portell, Jordi, de Mello, Gustavo Frederico Porto, Poyatos, Julien, Pozuelos, Francisco J., Moroni, Pier Giorgio Prada, Pricopi, Dumitru, Prisinzano, Loredana, Quade, Matthias, Quirrenbach, Andreas, Reina, Julio Arturo Rabanal, Soares, Maria Cristina Rabello, Raimondo, Gabriella, Rainer, Monica, Rodón, Jose Ramón, Ramón-Ballesta, Alejandro, Zapata, Gonzalo Ramos, Rätz, Stefanie, Rauterberg, Christoph, Redman, Bob, Redmer, Ronald, Reese, Daniel, Regibo, Sara, Reiners, Ansgar, Reinhold, Timo, Renie, Christian, Ribas, Ignasi, Ribeiro, Sergio, Ricciardi, Thiago Pereira, Rice, Ken, Richard, Olivier, Riello, Marco, Rieutord, Michel, Ripepi, Vincenzo, Rixon, Guy, Rockstein, Steve, Ortiz, José Ramón Rodón, Rodríguez, María Teresa Rodrigo, Amor, Alberto Rodríguez, Díaz, Luisa Fernanda Rodríguez, Garcia, Juan Pablo Rodriguez, Rodriguez-Gomez, Julio, Roehlly, Yannick, Roig, Fernando, Rojas-Ayala, Bárbara, Rolf, Tobias, Rørsted, Jakob Lysgaard, Rosado, Hugo, Rosotti, Giovanni, Roth, Olivier, Roth, Markus, Rousseau, Alex, Roxburgh, Ian, Roy, Fabrice, Royer, Pierre, Ruane, Kirk, Mastropasqua, Sergio Rufini, de Galarreta, Claudia Ruiz, Russi, Andrea, Saar, Steven, Saillenfest, Melaine, Salaris, Maurizio, Salmon, Sebastien, Saltas, Ippocratis, Samadi, Réza, Samadi, Aunia, Samra, Dominic, da Silva, Tiago Sanches, Carrasco, Miguel Andrés Sánchez, Santerne, Alexandre, Pé, Amaia Santiago, Santoli, Francesco, Santos, ngela R. G., Mesa, Rosario Sanz, Sarro, Luis Manuel, Scandariato, Gaetano, Schäfer, Martin, Schlafly, Edward, Schmider, François-Xavier, Schneider, Jean, Schou, Jesper, Schunker, Hannah, Schwarzkopf, Gabriel Jörg, Serenelli, Aldo, Seynaeve, Dries, Shan, Yutong, Shapiro, Alexander, Shipman, Russel, Sicilia, Daniela, sanmartin, Maria Angeles Sierra, Sigot, Axelle, Silliman, Kyle, Silvotti, Roberto, Simon, Attila E., Napoli, Ricardo Simoyama, Skarka, Marek, Smalley, Barry, Smiljanic, Rodolfo, Smit, Samuel, Smith, Alexis, Smith, Leigh, Snellen, Ignas, Sódor, Ádám, Sohl, Frank, Solanki, Sami K., Sortino, Francesca, Sousa, Sérgio, Southworth, John, Souto, Diogo, Sozzetti, Alessandro, Stamatellos, Dimitris, Stassun, Keivan, Steller, Manfred, Stello, Dennis, Stelzer, Beate, Stiebeler, Ulrike, Stokholm, Amalie, Storelvmo, Trude, Strassmeier, Klaus, Strøm, Paul Anthony, Strugarek, Antoine, Sulis, Sophia, vanda, Michal, Szabados, László, Szabó, Róbert, Szabó, Gyula M., Szuszkiewicz, Ewa, Talens, Geert Jan, Teti, Daniele, Theisen, Tom, Thévenin, Frédéric, Thoul, Anne, Tiphene, Didier, Titz-Weider, Ruth, Tkachenko, Andrew, Tomecki, Daniel, Tonfat, Jorge, Tosi, Nicola, Trampedach, Regner, Traven, Gregor, Triaud, Amaury, Trønnes, Reidar, Tsantaki, Maria, Tschentscher, Matthias, Turin, Arnaud, Tvaruzka, Adam, Ulmer, Bernd, Ulmer-Moll, Solène, Ulusoy, Ceren, Umbriaco, Gabriele, Valencia, Diana, Valentini, Marica, Valio, Adriana, Guijarro, Ángel Luis Valverde, Van Eylen, Vincent, Van Grootel, Valerie, van Kempen, Tim A., Van Reeth, Timothy, Van Zelst, Iris, Vandenbussche, Bart, Vasiliou, Konstantinos, Vasilyev, Valeriy, de Mascarenhas, David Vaz, Vazan, Allona, Nunez, Marina Vela, Velloso, Eduardo Nunes, Ventura, Rita, Ventura, Paolo, Venturini, Julia, Trallero, Isabel Vera, Veras, Dimitri, Verdugo, Eva, Verma, Kuldeep, Vibert, Didier, Martinez, Tobias Vicanek, Vida, Krisztián, Vigan, Arthur, Villacorta, Antonio, Villaver, Eva, Aparicio, Marcos Villaverde, Viotto, Valentina, Vorobyov, Eduard, Vorontsov, Sergey, Wagner, Frank W., Walloschek, Thomas, Walton, Nicholas, Walton, Dave, Wang, Haiyang, Waters, Rens, Watson, Christopher, Wedemeyer, Sven, Weeks, Angharad, Weingrill, Jörg, Weiss, Annita, Wendler, Belinda, West, Richard, Westerdorff, Karsten, Westphal, Pierre-Amaury, Wheatley, Peter, White, Tim, Whittaker, Amadou, Wickhusen, Kai, Wilson, Thomas, Windsor, James, Winter, Othon, Winther, Mark Lykke, Winton, Alistair, Witteck, Ulrike, Witzke, Veronika, Woitke, Peter, Wolter, David, Wuchterl, Günther, Wyatt, Mark, Yang, Dan, Yu, Jie, Sanchez, Ricardo Zanmar, Osorio, María Rosa Zapatero, Zechmeister, Mathias, Zhou, Yixiao, Ziemke, Claas, and Zwintz, Konstanze
Subjects: Astrophysics - Instrumentation and Methods for Astrophysics, Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Solar and Stellar Astrophysics
Abstract: PLATO (PLAnetary Transits and Oscillations of stars) is ESA's M3 mission designed to detect and characterise extrasolar planets and perform asteroseismic monitoring of a large number of stars. PLATO will detect small planets (down to <2 R_(Earth)) around bright stars (<11 mag), including terrestrial planets in the habitable zone of solar-like stars. With the complement of radial velocity observations from the ground, planets will be characterised for their radius, mass, and age with high accuracy (5 %, 10 %, 10 % for an Earth-Sun combination respectively). PLATO will provide us with a large-scale catalogue of well-characterised small planets up to intermediate orbital periods, relevant for a meaningful comparison to planet formation theories and to better understand planet evolution. It will make possible comparative exoplanetology to place our Solar System planets in a broader context. In parallel, PLATO will study (host) stars using asteroseismology, allowing us to determine the stellar properties with high accuracy, substantially enhancing our knowledge of stellar structure and evolution. The payload instrument consists of 26 cameras with 12cm aperture each. For at least four years, the mission will perform high-precision photometric measurements. Here we review the science objectives, present PLATO's target samples and fields, provide an overview of expected core science performance as well as a description of the instrument and the mission profile at the beginning of the serial production of the flight cameras. PLATO is scheduled for a launch date end 2026. This overview therefore provides a summary of the mission to the community in preparation of the upcoming operational phases.
Published: 2024

29. Cooperative learning of Pl@ntNet's Artificial Intelligence algorithm: how does it work and how can we improve it?

Author: Lefort, Tanguy, Affouard, Antoine, Charlier, Benjamin, Lombardo, Jean-Christophe, Chouet, Mathias, Goëau, Hervé, Salmon, Joseph, Bonnet, Pierre, and Joly, Alexis
Subjects: Computer Science - Machine Learning, Statistics - Applications
Abstract: Deep learning models for plant species identification rely on large annotated datasets. The PlantNet system enables global data collection by allowing users to upload and annotate plant observations, leading to noisy labels due to diverse user skills. Achieving consensus is crucial for training, but the vast scale of collected data makes traditional label aggregation strategies challenging. Existing methods either retain all observations, resulting in noisy training data or selectively keep those with sufficient votes, discarding valuable information. Additionally, as many species are rarely observed, user expertise can not be evaluated as an inter-user agreement: otherwise, botanical experts would have a lower weight in the AI training step than the average user. Our proposed label aggregation strategy aims to cooperatively train plant identification AI models. This strategy estimates user expertise as a trust score per user based on their ability to identify plant species from crowdsourced data. The trust score is recursively estimated from correctly identified species given the current estimated labels. This interpretable score exploits botanical experts' knowledge and the heterogeneity of users. Subsequently, our strategy removes unreliable observations but retains those with limited trusted annotations, unlike other approaches. We evaluate PlantNet's strategy on a released large subset of the PlantNet database focused on European flora, comprising over 6M observations and 800K users. We demonstrate that estimating users' skills based on the diversity of their expertise enhances labeling performance. Our findings emphasize the synergy of human annotation and data filtering in improving AI performance for a refined dataset. We explore incorporating AI-based votes alongside human input. This can further enhance human-AI interactions to detect unreliable observations.
Published: 2024

30. The set of Kirkwood-Dirac positive states is almost always minimal

Author: Langrenez, Christopher, Salmon, Wilfred, De Bièvre, Stephan, Thio, Jonathan J., Long, Christopher K., and Arvidsson-Shukur, David R. M.
Subjects: Quantum Physics, Mathematical Physics
Abstract: A central problem in quantum information is determining quantum-classical boundaries. A useful notion of classicality is provided by the quasiprobability formulation of quantum theory. In this framework, a state is called classical if it is represented by a quasiprobability distribution that is positive, and thus a probability distribution. In recent years, the Kirkwood-Dirac (KD) distributions have gained much interest due to their numerous applications in modern quantum-information research. A particular advantage of the KD distributions is that they can be defined with respect to arbitrary observables. Here, we show that if two observables are picked at random, the set of classical states of the resulting KD distribution is a simple polytope of minimal size. When the Hilbert space is of dimension $d$, this polytope is of dimension $2d-1$ and has $2d$ known vertices. Our result implies, $\textit{e.g.}$, that almost all KD distributions have resource theories in which the free states form a small and simple set., Comment: 12 pages
Published: 2024

31. Multi-Stakeholder Call to Action for the Future of Vaccine Post-Marketing Monitoring: Proceedings from the First Beyond COVID-19 Monitoring Excellence (BeCOME) Conference: Multi-Stakeholder Call to Action for the Future of Vaccine Post-Marketing Monitoring

Author: Bauchau, Vincent, Bollaerts, Kaatje, Bryan, Phil, Buttery, Jim, Davis, Kourtney, Chen, Robert T., Feikin, Daniel R., Fretta, Antonella, Frise, Sarah, Gandhi-Banga, Sonja, Izurieta, Hector S., Jouquelet-Royer, Corinne, Khromava, Alena, Li, Lin, Long, Raj, MacDonald, Sarah, Marcelon, Lydie, Massouh, Robert, Meeraus, Wilhelmine, Munoz, Flor M., Naim, Karen, Nordenberg, Dale, Nohynek, Hanna, Rubino, Heather, Salmon, Daniel A., Sellers, Sarah, Serradell, Laurence, Torcel-Pagnon, Laurence, and Wilkins, Jamie
Published: 2025
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32. Comparing adolescent glomerular disease clinical outcomes to the clinical outcomes in childhood, young adult, and adult-onset glomerular disease in the CureGN database

Author: Garrity, Kelly, Putnam, Nathaniel, Kamil, Elaine S., Massengill, Susan, Khalid, Myda, Srivastava, Rachana, Isaacs, Jaya, and Salmon, Eloise
Published: 2024
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33. Understanding rare genetic variants within the terminal pathway of complement system in preeclampsia

Author: Lokki, A. Inkeri, Triebwasser, Michael, Daly, Emma, Kurki, Mitja I., Perola, Markus, Auro, Kirsi, Salmon, Jane E., Anuja, Java, Daly, Mark, Atkinson, John P., Laivuori, Hannele, and Meri, Seppo
Published: 2024
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34. Impartial geodetic building games on graphs: Impartial geodetic building games on graphs

Author: Benesh, Bret J., Ernst, Dana C., Meyer, Marie, Salmon, Sarah K., and Sieben, Nándor
Published: 2024
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35. Challenges of Continuous Wave EPR of Broad Signals—The Ferritin Case

Author: Otsuka, Fabio Seiji, García Otaduy, Maria Concepción, Nascimento, Otaciro Rangel, Garrido Salmon, Carlos Ernesto, and Huber, Martina
Published: 2024
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36. Mexican Clinical Practice Guidelines for Adult Overweight and Obesity Management

Author: Chávez-Manzanera, Emma A., Vera-Zertuche, Juan M., Kaufer-Horwitz, Martha, Vázquez-Velázquez, Verónica, Flores-Lázaro, José R., Mireles-Zavala, Leonor, Calzada-León, Raúl, Garnica-Cuellar, Juan C., Sánchez-Muñoz, Verónica, Ramírez-Butanda, Eduardo, Hernández-González, Ricardo, Vargas-Martínez, María A., Laviada-Molina, Hugo, Violante-Ortíz, Rafael, Esquivias-Zavala, Héctor, García-García, Eduardo, Lavalle-González, Fernando J., Mancillas-Adame, Leonardo, López-Alvarenga, Juan C., Pérez-Hernández, Juan F., Soto-Fuentes, Erika V., Soriano-Cortés, Reina R., Goicoechea-Turcott, Eduardo W., Magallanes-Díaz, Gerardo, Herrera-Hernández, Miguel F., Barquera-Cervera, Simón, Vargas-Contreras, Edith, Díaz-Wionczek, Cybele B., Salmon, Morgan, Jesús, Dinorah Ramírez-De, Villaseñor-Díaz, Juan P., Peña, Javiera, Ramos-Rojas, José, Ávila-Oliver, Camila, Rada, Gabriel, Hussey, Brad, and Salas, Ximena Ramos
Published: 2024
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37. Nutrition and Golf Performance: A Systematic Scoping Review

Author: O’Donnell, Amy, Murray, Andrew, Nguyen, Alice, Salmon, Thomas, Taylor, Sam, Morton, James P., and Close, Graeme L.
Published: 2024
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38. Critical Factors in Lab-Scale Compostability Testing

Author: Wyman, Diana A. and Salmon, Sonja
Published: 2024
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39. The Female Competition Stress Test: Effects on Disordered Eating Beyond Adolescence

Author: Salmon, Catherine and Hehman, Jessica
Published: 2024
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40. Management of Device Detected Subclinical Atrial Fibrillation

Author: Salmon, Thomas, Calvert, Peter, and Lip, Gregory Y. H.
Published: 2024
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41. Representation of the academic workforce in English university strategy-making: an exploratory study

Author: Salmon, Michael
Published: 2024
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42. The Association Between Adolescent Vaping and Subsequent Use of Other Substances and Risk Factors for Polysubstance Use

Author: Salmon, Samantha, Pappas, Katerina V., Taillieu, Tamara L., Stewart-Tufescu, Ashley, Sareen, Jitender, MacMillan, Harriet L., Tonmyr, Lil, Brownell, Marni, Nickel, Nathan C., and Afifi, Tracie O.
Published: 2024
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43. Comparative lifespan and healthspan of nonhuman primate species common to biomedical research

Author: Huber, Hillary F., Ainsworth, Hannah C., Quillen, Ellen E., Salmon, Adam, Ross, Corinna, Azhar, Adinda D., Bales, Karen, Basso, Michele A., Coleman, Kristine, Colman, Ricki, Darusman, Huda S., Hopkins, William, Hotchkiss, Charlotte E., Jorgensen, Matthew J., Kavanagh, Kylie, Li, Cun, Mattison, Julie A., Nathanielsz, Peter W., Saputro, Suryo, Scorpio, Diana G., Sosa, Paul-Michael, Vallender, Eric J., Wang, Yaomin, Zeiss, Caroline J., Shively, Carol A., and Cox, Laura A.
Published: 2024
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44. Head Kinematics Associated with Off-Field Head Injury Assessment (HIA1) Events in a Season of English Elite-Level Club Men’s and Women’s Rugby Union Matches

Author: Allan, David, Tooby, James, Starling, Lindsay, Tucker, Ross, Falvey, Éanna, Salmon, Danielle, Brown, James, Hudson, Sam, Stokes, Keith, Jones, Ben, Kemp, Simon, O’Halloran, Patrick, Cross, Matt, Bussey, Melanie, and Tierney, Gregory
Published: 2024
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45. The effect of methylation on the let-7-BCL2L1-BCL2 axis and the potential use of hypomethylating and BH3 mimetic drugs in histiocytic neoplasms

Author: Salmon-Divon, Mali, Meyuchas, Refael, Shpilberg, Ofer, Okon, Elimelech, Benhamida, Jamal, Yabe, Mariko, Petrova-Drus, Kseniya, Zvida-Bloch, Tal, Basood, May, Mazor, Roei, Durham, Benjamin H., Haroche, Julien, Abdel-Wahab, Omar, Diamond, Eli L., and Hershkovitz-Rokah, Oshrat
Published: 2024
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46. Diagnosis of Alzheimer’s disease using plasma biomarkers adjusted to clinical probability

Author: Therriault, Joseph, Janelidze, Shorena, Benedet, Andréa Lessa, Ashton, Nicholas J., Arranz Martínez, Javier, Gonzalez-Escalante, Armand, Bellaver, Bruna, Alcolea, Daniel, Vrillon, Agathe, Karim, Helmet, Mielke, Michelle M., Hyung Hong, Chang, Roh, Hyun Woong, Contador, José, Puig Pijoan, Albert, Algeciras-Schimnich, Alicia, Vemuri, Prashanthi, Graff-Radford, Jonathan, Lowe, Val J., Karikari, Thomas K., Jonaitis, Erin, Brum, Wagner, Tissot, Cécile, Servaes, Stijn, Rahmouni, Nesrine, Macedo, Arthur C., Stevenson, Jenna, Fernandez-Arias, Jaime, Wang, Yi-Ting, Woo, Marcel S., Friese, Manuel A., Jia, Wan Lu, Dumurgier, Julien, Hourregue, Claire, Cognat, Emmanuel, Ferreira, Pamela Lukasewicz, Vitali, Paolo, Johnson, Sterling, Pascoal, Tharick A., Gauthier, Serge, Lleó, Alberto, Paquet, Claire, Petersen, Ronald C., Salmon, David, Mattsson-Carlgren, Niklas, Palmqvist, Sebastian, Stomrud, Erik, Galasko, Douglas, Son, Sang Joon, Zetterberg, Henrik, Fortea, Juan, Suárez-Calvet, Marc, Jack, Jr, Clifford R., Blennow, Kaj, Hansson, Oskar, and Rosa-Neto, Pedro
Published: 2024
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47. Thyrotropin (TSH) and thyroid autoimmunity are predictive factors for the incidental discovery of papillary thyroid microcarcinoma during thyroidectomy

Author: Kyrilli, Aglaia, Schoinochoriti, Rafaella, Chatzopoulos, Valerie, Bahar, Nabila, Bouziotis, Jason, D’Haene, Nicky, Salmon, Isabelle, Ruiz, Maria, and Corvilain, Bernard
Published: 2024
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48. Brain morphometry and estimation of aging brain in subjects with congenital untreated isolated GH deficiency

Author: Villar-Gouy, Keila R., Salmon, Carlos Ernesto Garrido, Salvatori, Roberto, Kellner, Michael, Krauss, Miriam P. O., Rocha, Tâmara O., de Souza, Erick Almeida, Batista, Vanderlan O., Leal, Ângela C., Santos, Lucas B., Melo, Enaldo V., Oliveira-Santos, Alécia A., Oliveira, Carla R. P., Campos, Viviane C., Santos, Elenilde G., Santana, Nathalie O., Pereira, Francisco A., Amorim, Rivia S., Donato-Junior, José, Filho, José Augusto Soares Barreto, Santos, Antonio Carlos, and Aguiar-Oliveira, Manuel H.
Published: 2024
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49. RNA Dynamics from Experimental and Computational Approaches

Author: Bussi, Giovanni, Bonomi, Massimiliano, Gkeka, Paraskevi, Sattler, Michael, Al-Hashimi, Hashim M., Auffinger, Pascal, Duca, Maria, Foricher, Yann, Incarnato, Danny, Jones, Alisha N., Kirmizialtin, Serdal, Krepl, Miroslav, Orozco, Modesto, Palermo, Giulia, Pasquali, Samuela, Salmon, Loïc, Schwalbe, Harald, Westhof, Eric, and Zacharias, Martin
Subjects: Quantitative Biology - Biomolecules, Physics - Biological Physics
Abstract: Ribonucleic acids (RNA) are unique in that they can store genetic information, replicate and perform catalysis. Importantly, RNA molecules are highly dynamic, and thus determining the ensemble of conformations that they populate is crucial not only to elucidate their biological functions, but also for their potential use as therapeutic targets. Computational and experimental techniques provide complementary views on RNA dynamics, and their integration is fundamental to improve the accuracy of computations and the resolution of experiments. Recent exciting developments in this field, were discussed at the CECAM workshop ``RNA dynamics from experimental and computational approaches'', in Paris, June 26-28, 2023. This report outlines key `take-home' messages that emerged during this workshop from the presentations and discussions.
Published: 2024
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50. James-Stein Estimation in Quantum Gaussian Sensing

Author: Salmon, Wilfred, Strelchuk, Sergii, and Arvidsson-Shukur, David
Subjects: Quantum Physics
Abstract: The James-Stein estimator is a biased estimator -- for a finite number of samples its expected value is not the true mean. The maximum-likelihood estimator (MLE), is unbiased and asymptotically optimal. Yet, when estimating the mean of $3$ or more normally-distributed random variables, the James-Stein estimator has a smaller total (expected) error than the MLE. We introduce the James-Stein estimator to the field of quantum metrology, from both the frequentist and Bayesian perspectives. We characterise the effect of quantum phenomena on the James-Stein estimator through the lens of quantum Gaussian sensing, the task of estimating the mean of an unknown multivariate quantum Gaussian state. We find that noiseless entanglement or coherence improves performance of the James-Stein estimator, but diminishes its advantage over the MLE. In the presence of noise, the James-Stein advantage is restored. Quantum effects can also boost the James-Stein advantage. We demonstrate this by investigating multivariate postselective metrology (generalised weak-value amplification), a strategy that uses quantum effects to measure parameters with imperfect detectors. Simply by post-processing measured data differently, our techniques reduce errors in quantum experiments.
Published: 2024

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