8 results on '"Scognamiglio, Paola"'
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2. How habitat factors affect an Aedes mosquitoes driven outbreak at temperate latitudes: The case of the Chikungunya virus in Italy
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Solimini, Angelo, primary, Virgillito, Chiara, additional, Manica, Mattia, additional, Poletti, Piero, additional, Guzzetta, Giorgio, additional, Marini, Giovanni, additional, Rosà, Roberto, additional, Filipponi, Federico, additional, Scognamiglio, Paola, additional, Vairo, Francesco, additional, and Caputo, Beniamino, additional
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- 2023
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3. Outbreaks of autochthonous Dengue in Lazio region, Italy, August to September 2023: preliminary investigation.
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De Carli, Gabriella, Carletti, Fabrizio, Spaziante, Martina, Maria Gruber, Cesare Ernesto, Rueca, Martina, Spezia, Pietro Giorgio, Vantaggio, Valentina, Barca, Alessandra, De Liberato, Claudio, Romiti, Federico, Scicluna, Maria Teresa, Vaglio, Stefania, Feccia, Mariano, Di Rosa, Enrico, Gianzi, Francesco Paolo, Giambi, Cristina, Scognamiglio, Paola, Nicastri, Emanuele, Girardi, Enrico, and Maggi, Fabrizio
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- 2023
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4. Genomic and Epidemiologic Surveillance of SARS-CoV-2 in the Pandemic Period: Sequencing Network of the Lazio Region, Italy.
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Rueca, Martina, Berno, Giulia, Agresta, Alessandro, Spaziante, Martina, Gruber, Cesare Ernesto Maria, Fabeni, Lavinia, Giombini, Emanuela, Butera, Ornella, Barca, Alessandra, Scognamiglio, Paola, Girardi, Enrico, Maggi, Fabrizio, Valli, Maria Beatrice, and Vairo, Francesco
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COVID-19 pandemic ,PUBLIC health surveillance ,COVID-19 ,INFECTIOUS disease transmission ,NUCLEOTIDE sequencing ,GENOMICS - Abstract
Since the beginning of the COVID-19 pandemic, large-scale genomic sequencing has immediately pointed out that SARS-CoV-2 has rapidly mutated during the course of the pandemic, resulting in the emergence of variants with a public health impact. In this context, strictly monitoring the circulating strains via NGS has proven to be crucial for the early identification of new emerging variants and the study of the genomic evolution and transmission of SARS-CoV-2. Following national and international guidelines, the Lazio region has created a sequencing laboratory network (WGSnet-Lazio) that works in synergy with the reference center for epidemiological surveillance (SERESMI) to monitor the circulation of SARS-CoV-2. Sequencing was carried out with the aims of characterizing outbreak transmission dynamics, performing the genomic analysis of viruses infecting specific categories of patients (i.e., immune-depressed, travelers, and people with severe symptoms) and randomly monitoring variant circulation. Here we report data emerging from sequencing activities carried out by WGSnet-Lazio (from February 2020 to October 2022) linked with epidemiological data to correlate the circulation of variants with the clinical and demographic characteristics of patients. The model of the sequencing network developed in the Lazio region proved to be a useful tool for SARS-CoV-2 surveillance and to support public health measures for epidemic containment. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Risk of parenterally transmitted hepatitis following exposure to invasive procedures in Italy: SEIEVA surveillance 2000-2021
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Caminada, Susanna, primary, Mele, Annamaria, additional, Ferrigno, Luigina, additional, Alfonsi, Valeria, additional, Crateri, Simonetta, additional, Iantosca, Giuseppina, additional, Sabato, Marise, additional, Tosti, Maria Elena, additional, D’Angelo, Franca, additional, Zotti, Carla, additional, Marengo, Noemi, additional, Cornio, Alessandro Roberto, additional, Russotto, Antonino, additional, Scarvaglieri, Maria Elisabetta, additional, Gallone, Angela, additional, Zoia, Irene, additional, Torchio, Pierfederico, additional, Melcarne, Lucia, additional, Castagno, Paolo, additional, Bassetti, Saveria, additional, Dama, Erika, additional, Orlandi, Silvia, additional, Busso, Stefania, additional, Andreoletti, Michela, additional, Fontana, Manuela, additional, Rametta, Stefania, additional, Cranco, Rosita, additional, Bonacina, Alessandra, additional, Lioce, Duilio, additional, Ciprioti, Rosamary, additional, Cappello, Maria Teresa, additional, Palma, Anna Maria, additional, Musso, Claudia, additional, Bussolino, Paola, additional, Smaniotto, Alessandro, additional, Ruffier, Mario, additional, Verardo, Marina, additional, Cipriani, Alessandro, additional, Cereda, Danilo, additional, Senatore, Sabrina, additional, Donadini, Annalisa, additional, Nespoli, Carla, additional, Gennati, Giorgio, additional, Piro, Antonio, additional, Vezzosi, Luigi, additional, Conca, Matteo, additional, Romani, Michela, additional, Tortorella, Franco Paolo, additional, Merlini, Paola Elvira, additional, Di Caterina, Davide, additional, Faccini, Marino, additional, Lamberti, Anna, additional, Rossetti, Eva, additional, Brugnoli, Rita, additional, Mainardi, Giulia, additional, Vezzoli, Alessandra, additional, Caso, Daniela, additional, Testa, Milena, additional, Costa, Daniela, additional, Senegaglia, Paola, additional, Spagna, Annamaria, additional, Lodola, Silvia, additional, Riboli, Simona, additional, Giompapa, Enza, additional, Roveri, Luigi Guido, additional, Guardigli, Gabriele, additional, Scalvinoni, Vanna, additional, Lombarda, Elena, additional, Gasparri, Serena, additional, Spertini, Silvia, additional, Gamper, Sabine, additional, Moretto, Giacomo, additional, Kofler, Elisabeth, additional, Ploner, Barbara, additional, Runggatscher, Verena, additional, Molinaro, Silvia, additional, Zuccali, Maria Grazia, additional, Franchini, Silvia, additional, Russo, Francesca, additional, Zanella, Francesca, additional, Ballarin, Debora, additional, Fiorito, Nahuel, additional, Zallot, Chiara, additional, Cian, Serena, additional, Bonsembiante, Erminio, additional, Mattiuzzo, Elena, additional, Munarin, Ludovica, additional, Palazzi, Barbara, additional, Sulaj, Arda, additional, Boin, Federica, additional, Carraro, Daniele, additional, Codolo, Antonella, additional, Fragapane, Marilena, additional, Formaglio, Andrea, additional, Giacobbe, Donatella, additional, Fenzi, Federica, additional, Gottardello, Lorena, additional, Cannizzo, Elisabetta, additional, Ceccon, Giulia, additional, De Stefani, Emanuela, additional, Casagrande, Paola, additional, Zotto, Alessandra Dal, additional, Zotto, Rita Dal, additional, Carlotto, Antonio, additional, Zorzi, Gemma, additional, Ivanovska, Sandra, additional, Postiglione, Chiara, additional, Colucci, Laura, additional, Rocco, Giulio, additional, Stacul, Rossana, additional, Breda, Ariella, additional, Bortolossi, Marisa, additional, Iob, Andrea, additional, Micossi, Simonetta, additional, Feltrin, Oriana, additional, Caernelos, Giuseppina, additional, Mela, Marco, additional, Frumento, Virna, additional, Opisso, Anna, additional, Cuccu, Alessandro, additional, Carpi, Antonella, additional, Giuffra, Paola, additional, Torracca, Francesca, additional, Castiglioni, Laura, additional, Mattei, Giovanna, additional, Gualanduzzi, Claudio, additional, Massimiliani, Erika, additional, Rampini, Alessandra, additional, Paglioli, Silvia, additional, Bisaccia, Eufemia, additional, Roversi, Sandra, additional, Resi, Davide, additional, Prengka, Anna, additional, Califano, Annalisa, additional, Santoro, Viviana, additional, Biguzzi, Emilia, additional, Reali, Chiara, additional, Morri, Michela, additional, Senatore, Daniela, additional, Balocchini, Emanuela, additional, Pierozzi, Costanza, additional, Angio, Francesco, additional, Kundisova, Lucia, additional, Isola, Alda, additional, Cecconi, Rossella, additional, Berti, Cristiana, additional, Matarazzo, Francesca, additional, Zini, Paola, additional, Staderini, Chiara, additional, Cordella, Vincenzo, additional, Brugnoli, Sara, additional, Sacchelli, Francesco, additional, Lucchesi, Lara, additional, Luzzoli, Rosa, additional, Gandolfo, Silvia, additional, Cibeca, Piero, additional, Galletti, Nicoletta, additional, Aquino, Francesco, additional, Lari, Maria, additional, Poropat, Roberta, additional, Ferrini, Rita, additional, Barbieri, Alessandro, additional, Conti, Vito, additional, Canale, Alice, additional, Moretti, Katia, additional, Buccino, Aniello, additional, Bartoli, Ilaria, additional, Cioni, Silvia, additional, Gennari, Giulia, additional, Rapaccini, Fabiola, additional, Bekshiu, Lumturi, additional, Zacchini, Federica, additional, Romani, Davide, additional, Sansone, Monica, additional, Foresi, Simona, additional, Piattellini, Giovanni, additional, Pasquale, Anna, additional, Brancaleoni, Maria Grazia, additional, Santocchia, Franco, additional, Proietti, Maria Laura, additional, Fiacchini, Daniel, additional, Giamprini, Maria Sole, additional, Iacobellis, Mariangela, additional, Van Will, Jacqueline, additional, Vaccaro, Alfredo, additional, Sbarbati, Maria Margherita, additional, Amelio, Alessandra, additional, Cimini, Daniela, additional, Moroni, Vania, additional, Francoletti, Daniela, additional, Marcellini, Mirella, additional, Scaccia, Federica, additional, Branchesi, Elisabetta, additional, Saracino, Selena, additional, Mezzanotte, Catia, additional, Cimica, Susanna, additional, Vitale, Vita, additional, Laici, Franca, additional, Petrelli, Irene, additional, Airini, Barbara, additional, Passarini, Gabriella, additional, Ruffini, Lucia, additional, Lambertucci, Anna Maria, additional, Mogetta, Annarita, additional, Ciarrocchi, Giuseppe, additional, Pistolesi, Marina, additional, Fratello, Erika, additional, Picciotti, Francesca, additional, Contrisciani, Roberta, additional, Angelini, Claudio, additional, Ribiscini, Silvia, additional, Scognamiglio, Paola, additional, Vairo, Francesco, additional, De Santis, Claudia, additional, Miglietta, Antonio Salvatore, additional, Colosi, Alberto, additional, Loffredo, Maria Rosaria, additional, Esterini, Giorgio, additional, Pendenza, Alessio, additional, Nappi, Maria Rosaria, additional, Casagni, Luca, additional, Santucci, Luigi, additional, Montecchi, Margherita, additional, Mangiagli, Franca, additional, Aquilani, Silvia, additional, Di Luzio, Giuseppe, additional, Provvidenti, Luca, additional, Giambi, Cristina, additional, Di Giacomo, Manuela, additional, Giansanti, Enrico, additional, Mancini, Cristiana, additional, Turchi, Claudio, additional, Soldato, Graziella, additional, D'Eugenio, Felesina, additional, Albanesi, Ida, additional, Montanaro, Carmen, additional, Di Giorgio, Giovanni, additional, Prozzo, Alessandra, additional, Sabatini, Paola, additional, Simonelli, Mena, additional, Morrone, Gaetano, additional, Citarella, Annarita, additional, Fossi, Elena, additional, Alfieri, Rosa, additional, Scotto, Milena, additional, Caiazzo, Anna Luisa, additional, Liquori, Antonia, additional, Chironna, Maria, additional, Prato, Rosa, additional, Martinelli, Domenico, additional, Fortunato, Francesca, additional, Cappelli, Maria Giovanna, additional, Loconsole, Daniela, additional, Morea, Anna, additional, Del Matto, Giulia, additional, Maluccio, Maria Giuseppina, additional, Pedote, Pasquale, additional, Termite, Stefano, additional, Cambria, Roberta, additional, Caputi, Giovanni, additional, Cipriani, Rosati, additional, Desiante, Francesco, additional, Menolascina, Stefania, additional, Laforgia, Vera, additional, Squicciarini, Rosella, additional, Vitale, Viviana, additional, Matera, Anna Maria, additional, Pagone, Onofrio, additional, Avella, Grazia Maria, additional, Madaro, Antonino, additional, Angelillis, Raffaele, additional, Moffa, Giuseppina, additional, Nesta, Maria, additional, De Santis, Carlo, additional, Ferraro, Marisa, additional, Aprile, Valerio, additional, Antonazzo, Marcello, additional, Laugello, Giovanni, additional, Mignuoli, Anna Domenica, additional, Afflitto, Giuseppe, additional, Caroleo, Benedetto, additional, Scrivano, Francesca, additional, Maradei, Antonio, additional, Romeo, Rocco Cataldo, additional, Zucco, Rossella, additional, Coscarelli, Pierluigi, additional, Bisbano, Alessandro, additional, Monesanti, Maria, additional, De Giorgio, Vincenzo, additional, Giordano, Antonella, additional, Mammì, Pier Domenico, additional, Lazzarino, Elisa, additional, Surace, Vittoria, additional, Mangione, Rossana, additional, Meli, Valentina, additional, Cuccia, Mario, additional, Longhitano, Elena, additional, Delogu, Fiorenzo, additional, Fracasso, Donatella, additional, Marceddu, Maria Vittoria, additional, Flore, Loredana, additional, Eugenia Marras, Maria Valentina, additional, Serpi, Rita, additional, Campus, Marco, additional, and Raggio, Alessia, additional
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- 2023
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6. Air pollution, SARS-CoV-2 incidence and COVID-19 mortality in Rome: a longitudinal study
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Nobile, Federica, primary, Michelozzi, Paola, additional, Ancona, Carla, additional, Cappai, Giovanna, additional, Cesaroni, Giulia, additional, Davoli, Marina, additional, Di Martino, Mirko, additional, Nicastri, Emanuele, additional, Girardi, Enrico, additional, Beccacece, Alessia, additional, Scognamiglio, Paola, additional, Sorge, Chiara, additional, Vairo, Francesco, additional, and Stafoggia, Massimo, additional
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- 2022
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7. Genetic and structural characterization of dengue virus involved in the 2023 autochthonous outbreaks in central Italy.
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Carletti F, Carli G, Spezia PG, Gruber CEM, Prandi IG, Rueca M, Agresta A, Specchiarello E, Fabeni L, Giovanni ES, Arcuri C, Spaziante M, Focosi D, Scognamiglio P, Barca A, Nicastri E, Girardi E, Chillemi G, Vairo F, and Maggi F
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- Humans, Italy epidemiology, Serogroup, Male, Female, RNA, Viral genetics, Adult, Viral Envelope Proteins genetics, Viral Envelope Proteins chemistry, Middle Aged, Dengue Virus genetics, Dengue Virus classification, Dengue epidemiology, Dengue virology, Dengue transmission, Disease Outbreaks, Phylogeny, Genome, Viral
- Abstract
Dengue virus (DENV) has been expanding its range to temperate areas that are not usually affected, where the spread of vectors has been facilitated by global trade and climate change. In Europe, there have been many cases of DENV imported from other regions in the past few years, leading to local outbreaks of DENV among people without travel history. Here we describe the epidemiological and molecular investigations of three transmission events locally acquired DENV infections caused by serotypes 1, 2 and 3, respectively, in the Latium Region from August to November 2023. Next-generation or Sanger sequencing was used to obtain the whole genomes, or the complete E-gene of the viruses, respectively. The structure of the DENV-1 and DENV-3 sequences was analysed to identify amino acid changes that were not found in the closest related sequences. The major cluster was supported by DENV-1 (originated in South America), with 42 autochthonous infections almost occurring in the eastern area of Rome, probably due to a single introduction followed by local sustained transmission. Seven DENV-1 subclusters have been identified by mutational and phylogenetic analysis. Structural analysis indicated changes whose meaning can be explained by the adaptation of the virus to human hosts and vectors and their interactions with antibodies and cell receptors.
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- 2024
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8. Outbreaks of autochthonous Dengue in Lazio region, Italy, August to September 2023: preliminary investigation.
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De Carli G, Carletti F, Spaziante M, Gruber CEM, Rueca M, Spezia PG, Vantaggio V, Barca A, De Liberato C, Romiti F, Scicluna MT, Vaglio S, Feccia M, Di Rosa E, Gianzi FP, Giambi C, Scognamiglio P, Nicastri E, Girardi E, Maggi F, and Vairo F
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- Humans, Phylogeny, Italy epidemiology, Serogroup, Disease Outbreaks, Dengue epidemiology
- Abstract
Between August and September 2023, three distinct autochthonous dengue virus transmission events occurred in Lazio, Italy, with the main event in Rome. The events involved three different dengue serotypes. No link with previous imported cases was identified. Here we describe the epidemiological and phylogenetic analysis of the first autochthonous cases and the implemented control actions. The multiple transmission events call for a strengthening of the vector control strategies and future research to better characterise the risk in countries like Italy.
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- 2023
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