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Anterior pelvic ring injuries can be treated via Pfannenstiel, modified Stoppa, or ilioinguinal approaches, but these require exposing the abdominal soft tissues and may damage pelvic organs. The scar on the abdominal wall is also unacceptable for some patients. The minimally invasive anterior pelvic ring internal fixator (INFIX) is not ideal for thin patients with easily irritated skin, and it is associated with complications such as femoral nerve palsy, vascular occlusion, and lateral femoral cutaneous nerve injury. In this study, we designed a new external pelvic approach for the treatment of an anterior pelvic ring fracture.We retrospectively reviewed 28 patients with 36 pubic ramus fractures that had been treated via the covert-inferior pelvic approach. All patients underwent a surgical procedure between August 2019 and January 2021. According to the Nakatani classification, there were 6 cases of type-I fracture, 25 cases of type-II fracture, and 5 cases of type-III fracture. Operative time, blood loss, and postoperative radiographic and computed tomographic (CT) findings were recorded. Patients were followed for fracture healing time, functional status, esthetic satisfaction, and complications.A total of 27 patients had follow-up for at least 12 months (range, 12 to 29 months). Postoperative radiographs and CT scans showed well-positioned plates and screws. The mean preoperative time was 9.4 ± 3.8 days, the mean operative time was 61.3 ± 22.67 minutes, the mean intraoperative blood loss was 63.6 ± 42.62 mL, the mean fracture healing time was 4.1 ± 1.6 months, and the mean Majeed score was 89.74 ± 8.07. There were no complications of nonunion, internal fixation failure, vascular injury, nerve palsy, or hernia. All of the patients were esthetically satisfied with the scar.The covert-inferior pelvic approach combined with a subpubic plate effectively fixed Nakatani type-I, II, and III fractures. The advantages of this method include rapid recovery after the surgical procedure, safety, simplicity, a short learning curve, no damage to abdominal soft tissue, no effect on pubic symphysis micromotion, and esthetic benefits. It may be another option for anterior pelvic ring fractures and can supplement other approaches.Therapeutic Level III . See Instructions for Authors for a complete description of levels of evidence.

With the development of global value chains, more and more countries are involved in global trade, which has brought an extensive social impact. Past studies on the employment impact of trade have pointed out that free trade has significantly boosted employment in developing economies, with large populations working in export-related jobs along the value chains. Recently, the COVID-19 pandemic has caused global trade protectionism to become more rampant. This study aims to establish a trade employment effect accounting model, based on the comparison of multiple scenarios, to discuss the employment impact of trade lockdown on major developing and developed countries. Specifically, based on a multi-regional input–output model, we map the flow network of trade-induced employment in 15 major global economies, and the scenarios of free trade and restricted trade are simulated to determine the employment impact of protectionism across multiple trade patterns. The results show that the current labor flow induced by global trade mainly flows from developing countries such as China and India to developed countries such as the EU and the United States. In the total employment induced by trade, the proportion of final products trade reached 42.82%. Trade protection would cut 19.86 million jobs worldwide. Under the trade restriction scenario, employment in developing countries would be reduced, with China and India losing 45.24 million and 10.10 million jobs, respectively. People working in the final product processing trade face the greatest risk of unemployment, especially in manufacturing and services. Among developed countries, the EU and the US would add 5.52 and 2.23 million jobs due to industrial repatriation.

Osteomyelitis is a difficult-to-treat infectious disease. Treatment, which includes controlling the infection and removing necrotic tissues, is challenging. Considering the side effects and drug resistance of systemic antibiotics, local drug delivery systems are being explored. Antibiotic-loaded bone cement is the main treatment strategy; however, it has several disadvantages. Thus, based on its thermosensitive gelation properties, poly(D, L-lactide-co-glycolide)-poly(ethylene glycol)-poly(D, L-lactide-co-glycolide) (PLGA-PEG-PLGA) copolymer was used as a sustained-release drug carrier by calibrating its synthesis parameters. We prepared and characterized vancomycin@PLGA-PEG-PLGA/hydroxyapatite (HA) thermosensitive hydrogel with an LA/GA ratio of 15:1. The rheological characteristics, sol-gel phase-transition properties, and critical micelle concentration value of the PLGA-PEG-PLGA/HA complex confirmed that it undergoes a temperature-sensitive sol-gel phase transition. Furthermore, the HA in the composite increased the storage modulus of the system. FT-IR, XRD, and TEM findings showed that HA could be dispersed uniformly in the PLGA-PEG-PLGA polymer. Moreover, HA neutralized acidity during polymer degradation, improving in vitro cytocompatibility. In vitro and in vivo antibacterial experiments showed that the composite sustained-release system exhibited good bone repair characteristics owing to its efficacy in infection treatment. Therefore, vancomycin@PLGA-PEG-PLGA/HA allows sustained release of antibiotics and promotes bone tissue repair, showing potential for wide clinical applicability.

Penetration testing is an effective method of making computers secure. When conducting penetration testing, it is necessary to fully understand the various elements in the cyberspace. Prediction of future cyberspace state through perception and understanding of cyberspace can assist defenders in decision-making and action execution. Accurate cyberspace detection information is the key to ensuring successful penetration testing. However, cyberspace situation awareness still faces the following challenges. Due to the limited detection capability, the information obtained from cyberspace detection intelligence is incomplete. There are some errors in the cyberspace detection intelligence, which may mislead the penetration testing workers. The knowledge graph can store and manage the cybersecurity data. In order to ensure the integrity and accuracy of cyberspace information, we design a knowledge graph completion model called CSNT to complete cybersecurity data. CSNT uses the BiLSTM to capture the interaction information between entities and relationships. It models the relationship between entities by combining the neural network and tensor decomposition. The Pearson Mix Net is designed to control the generation of joint vectors. We also design a novel self-distillation strategy to reduce catastrophic forgetting during model training. After learning the relationship pattern between entities in the cyberspace detection intelligence, the model can be used to mine the knowledge not found in the cybersecurity detection intelligence and correct the erroneous records. Experiments show that our method has certain advantages for the knowledge graph completion.

MnO x nanomaterials are regarded as promising catalysts for degrading formaldehyde (HCHO). However, the catalytic nanoparticles (NPs) suffer from the catalysis performance and stability loss due to their weak combination with the substrates and easy-aggregation nature. Herein, we develop a facile method to synthesize hollow porous MnO x @NPs fibers via electrospinning and two-step oxidation. The NPs, e.g., TiO2 and SnO2, can be efficiently loaded into MnO x fibers’ inner frame through a simple dispersion process. The hollow porous structures obtained through two-step oxidation increase the HCHO removal efficiency by 8 times, while MnO x @SnO2 fibers exhibit the enhanced catalytic performance by 23.0% more.