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Your search keyword '"Shigeo Takata"' showing total 2 results
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2 results on '"Shigeo Takata"'

1. Relationships between muscle sympathetic nerve activity and novel indices of arterial stiffness using single oscillometric cuff in patients with hypertension

Author

Hiroyuki Sugimoto, Takuto Hamaoka, Hisayoshi Murai, Tadayuki Hirai, Yusuke Mukai, Takashi Kusayama, Shinichiro Takashima, Takeshi Kato, Shigeo Takata, Soichiro Usui, Kenji Sakata, Masa‐Aki Kawashiri, and Masayuki Takamura

Subjects
arterial pressure‐volume index, arterial stiffness, arterial velocity pulse index, hypertension, muscle sympathetic nerve activity, Physiology, QP1-981
Abstract

Abstract The arterial velocity pulse index (AVI) and arterial pressure‐volume index (API) have been proposed as new arterial stiffness indices that can be measured using an oscillometric cuff. Sympathetic nerve activity (SNA) contributes to arterial stiffness via increasing vascular smooth muscle tone. However, the associations between SNA and the AVI or API are not understood. The purpose of this study was to evaluate the relationships between muscle sympathetic nerve activity (MSNA) and the AVI or API in healthy individuals and patients with hypertension (HT). Forty healthy individuals (40.1 ± 15.2 years, 8 females) (healthy group) and 40 patients with HT (60.2 ± 13.6, 18 females) (HT group) were included in this study. The AVI, API, MSNA, beat‐by‐beat blood pressure, and heart rate were recorded simultaneously. The AVI and API were higher in the HT group than in the healthy group (AVI, 26.1 ± 7.6 vs. 16.5 ± 4.0, p

Published
2022
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2. Effect of pulmonary vein isolation on the relationship between left atrial reverse remodeling and sympathetic nerve activity in patients with atrial fibrillation

Author

Yusuke Mukai, Hisayoshi Murai, Takuto Hamaoka, Hiroyuki Sugimoto, Oto Inoue, Chiaki Goten, Takashi Kusayama, Shin-ichiro Takashima, Takeshi Kato, Soichiro Usui, Kenji Sakata, Shigeo Takata, and Masayuki Takamura

Subjects
Treatment Outcome, Endocrine and Autonomic Systems, Pulmonary Veins, Atrial Fibrillation, Catheter Ablation, Humans, Stroke Volume, Neurology (clinical), Heart Atria, Ventricular Function, Left
Abstract

Catheter ablation (CA) to isolate the pulmonary vein, which is an established treatment for atrial fibrillation (AF), is associated with left atrium reverse remodeling (LARR). The intrinsic cardiac autonomic nervous system includes the ganglion plexi adjacent to the pulmonary vein in the left atrium (LA). However, little is known about the effect of CA on the relationship between LARR and sympathetic nerve activity in patients with AF.This study enrolled 22 AF patients with a normal left ventricular ejection fraction (LVEF) aged 64.6 ± 12.9 years who were scheduled for CA. Sympathetic nerve activity was evaluated by direct recording of muscle sympathetic nerve activity (MSNA) before and 12 weeks after CA. Blood pressure, heart rate (HR), HR variability, and echocardiography were also measured.The heart rate increased significantly after CA (63 ± 10.9 vs. 70.6 ± 7.7 beats/min, p 0.01), but blood pressure did not change. A high frequency (HF) and low frequency (LF) of HR variability decreased significantly after ablation, but no significant change in LF/HF was observed. CA significantly decreased MSNA (38.9 ± 9.9 vs. 28 ± 9.1 bursts/min, p 0.01). Moreover, regression analysis revealed a positive correlation between the percentage change in MSNA and the LA volume index (r = 0.442, p 0.05).Our results show that CA for AF reduced MSNA and the decrease was associated with the LA volume index in AF patients with a normal LVEF. These findings suggest that LARR induced by CA for AF decrease sympathetic nerve activity.

Published
2022

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