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Background and purposePrevious studies suggest that mechanisms and outcomes in patients with COVID-19-associated stroke differ from those in patients with non-COVID-19-associated strokes, but there is limited comparative evidence focusing on these populations. The aim of this study, therefore, was to determine if a significant association exists between COVID-19 status with revascularization and functional outcomes following thrombectomy for large vessel occlusion (LVO), after adjustment for potential confounding factors.MethodsA cross-sectional, international multicenter retrospective study was conducted in consecutively admitted COVID-19 patients with concomitant acute LVO, compared to a control group without COVID-19. Data collected included age, gender, comorbidities, clinical characteristics, details of the involved vessels, procedural technique, and various outcomes. A multivariable-adjusted analysis was conducted.ResultsIn this cohort of 697 patients with acute LVO, 302 had COVID-19 while 395 patients did not. There was a significant difference (p

BackgroundThe mechanisms and outcomes in coronavirus disease (COVID-19)-associated stroke are unique from those of non-COVID-19 stroke.ObjectiveTo describe the efficacy and outcomes of acute revascularization of large vessel occlusion (LVO) in the setting of COVID-19 in an international cohort.MethodsWe conducted an international multicenter retrospective study of consecutively admitted patients with COVID-19 with concomitant acute LVO across 50 comprehensive stroke centers. Our control group constituted historical controls of patients presenting with LVO and receiving a mechanical thrombectomy between January 2018 and December 2020.ResultsThe total cohort was 575 patients with acute LVO; 194 patients had COVID-19 while 381 patients did not. Patients in the COVID-19 group were younger (62.5 vs 71.2; P < .001) and lacked vascular risk factors (49, 25.3% vs 54, 14.2%; P = .001). Modified thrombolysis in cerebral infarction 3 revascularization was less common in the COVID-19 group (74, 39.2% vs 252, 67.2%; P < .001). Poor functional outcome at discharge (defined as modified Ranklin Scale 3-6) was more common in the COVID-19 group (150, 79.8% vs 132, 66.7%; P = .004). COVID-19 was independently associated with a lower likelihood of achieving modified thrombolysis in cerebral infarction 3 (odds ratio [OR]: 0.4, 95% CI: 0.2-0.7; P < .001) and unfavorable outcomes (OR: 2.5, 95% CI: 1.4-4.5; P = .002).ConclusionCOVID-19 was an independent predictor of incomplete revascularization and poor outcomes in patients with stroke due to LVO. Patients with COVID-19 with LVO were younger, had fewer cerebrovascular risk factors, and suffered from higher morbidity/mortality rates.

Purpose: This qualitative study is grounded on in-depth interviews with 30 Western women self-initiated expatriate (SIEs) currently living and working in the UAE. When selecting the interviewees, the author used purposeful sampling to ensure a diverse sample of interviewees with respect to nationality, age, gender and occupation. Design/methodology/approach: The present study, drawing on boundary theory, aims to investigate the work–life balance (WLB) of Western women SIEs regarding how these women construct and manage the borders between the non-work and work lives in the United Arab Emirates (UAE). Findings: The results demonstrate that women SIEs experience conflicts and enrichment during overseas employment. Both directions – the impact flowing from working life to personal life and vice versa – were significant. Different career and life phases appeared to be crucial to these experiences. The study also found that some women SIEs in the UAE experience high pressure in the WLB approaches, which are primarily impacted by the specific work–life environment in the UAE. Mostly, work–life boundaries are culturally and socially induced. Hence, many women SIEs encounter disparities between the robust work–life separations in the home country compared to the host country; women SIEs, therefore, need to relax the boundaries to adapt to the competitive work–life environment in the UAE. Originality/value: The present study contributes to research on work–life boundary management approaches in local settings, such as UAE, by analyzing cross-cultural and individual dimensions. Moreover, although women are still a minority among SIEs, the number of women is increasing. As prior studies have mainly focused on male SIEs, more research is required focusing specifically on women with overseas jobs. The present study endeavors to fill this research gap. [ABSTRACT FROM AUTHOR]