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The single variable domains of camelid heavy-chain only antibodies, known as nanobodies, have taken a long journey since their discovery in 1989 until the first nanobody-based drug's entrance to the market in 2022. On account of their unique properties, nanobodies have been successfully used for diagnosis and therapy against various diseases or conditions. Although research on the application of recombinant antibodies has focused on human medicine, the development of nanobodies has paved the way for incorporating recombinant antibody production in favour of veterinary medicine. Currently, despite many efforts in developing these biomolecules with diversified applications, significant opportunities exist for exploiting these highly versatile and cost-effective antibodies in veterinary medicine. The present study attempts to identify existing gaps and shed light on paths for future research by presenting an updated review on camelid nanobodies with potential applications in veterinary medicine., (© 2024. The Author(s), under exclusive licence to Springer Nature B.V.)

Beak and feather disease virus (BFDV) is one of the most life-threatening viral agents infecting parrot species. In this study, we investigated fluctuation in the prevalence of beak and feather disease virus (BFDV) in captive psittacines in Iran. Two series of feather samples from different psittacine species, received between July 2019 and July 2021 (n = 1009) and between July 2021 and July 2022 (n = 2020), were examined for the presence of BFDV using the PCR method, and the host species distribution and temporal prevalence of BFDV within populations were calculated. The results showed a total viral prevalence of 26.86% and 26.88% within sample series 1 and 2, respectively. By examining both sample series, the prevalence of BFDV was found to be  the highest (P < 0.05) in Nymphicus hollandicus and the lowest (P < 0.05) in Psittacus erithacus, Myiopsitta monachus, Pyrrhura molinae, and Aratinga solstitialis. The viral prevalence was significantly higher (P < 0.05) within the series 1 than the series 2 samples only in Nymphicus hollandicus. Within series 2, the viral prevalence was significant (P < 0.05) in samples from Nymphicus hollandicus collected in March. This study indicates significant prevalence of BFDV in captive Nymphicus hollandicus populations and suggests that the fluctuation in the prevalence of BFDV could be due to the combined influence of host-species and temporal factors., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)

Cognitive satellite communication (SatCom) is rapidly emerging as a promising technology to overcome the scarcity of the exclusive licensed band model in order to fulfill the increasing demand for high data rate services. The paper addresses power allocation methods for multi-operator multi-beam uplink satellite communication systems co-existing with a Ka-band terrestrial network, using cognitive radio paradigm. Such a scenario is especially challenging because of (i) the coexisting multiple SatCom operators over the cognitive band need to coordinate the use of their resources under limited inter-operator information exchange, and (ii) nonlinear onboard high power amplifier (HPA) which leads to nonlinear interference between users and beams. In order to tackle the first challenge, we propose distributed power allocation algorithms including the standard Alternate Direction Multiplier Method (ADMM); Regarding the HPA nonlinear impairment, we propose nonlinear-aware power allocation based on Signomial Programming. The proposed solutions outperform state-of-the-art in both cases., Competing Interests: Conflict of interestsThe authors declare that they have no competing interests., (© The Author(s) 2023.)

Background: We aimed to evaluate the possibility of temporomandibular joint (TMJ) dysfunction following mandibular advancement surgery in skeletal class 2 patients., Methods: All healthy non-syndromic patients with Class 2 deformity, who were eligible for mandibular advancement surgery, were included in this before-after quasi-experimental study. The main intervention was mandibular advancement through bilateral sagittal split osteotomy (BSSO). Maxillary impaction or setback surgery using LeFort 1 osteotomy was simultaneously performed in some cases. Variables such as TMJ pain, clicking, crepitus, or any other type of sounds or complaint as well as the amount of maximum mouth opening (MMO) were evaluated before surgery and two months postoperatively., Results: Thirty patients including 15 men and 15 women with a mean age of 23.3 ±2.7 yr were studied. The mean amount of mandibular advancement displacement was 3.30 ± 0.87 mm. The rate of TMJ dysfunctions and complaints was relatively low two months postoperatively when compared to the preoperative state. Postoperative evaluation demonstrated that there was no significant correlation between the presence of TMJ symptoms and dysfunctions and the type of surgery. After treatment was completed, the mean MMO reduced significantly from 39.03±5.86 to 38.12±6.05 ( P <0.001)., Conclusion: Mandibular advancement with BSSO surgery in skeletal class 2 patients did not clinically lead to TMJ dysfunctions. Among all the investigated factors, only preoperative pain, noises, or complaints were proven to have predictive value for postoperative TMJ dysfunction., Competing Interests: None declared.