308 results on '"Tsumoto, Kouhei"'
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2. Thermodynamic and molecular dynamic insights into how fusion influences peptide-tag recognition of an antibody
3. THOUSAND-GRAIN WEIGHT 6, which is an IAA-glucose hydrolase, preferentially recognizes the structure of the indole ring
4. Structural basis for the recognition of human hemoglobin by the heme-acquisition protein Shr from Streptococcus pyogenes
5. Next-Generation Anti-TNFα Agents: The Example of Ozoralizumab
6. Raman spectroscopic analysis of highly-concentrated antibodies under the acid-treated conditions
7. Structural basis for the ligand promiscuity of the hydroxamate siderophore binding protein FtsB from Streptococcus pyogenes
8. Raman Spectroscopic Analysis of Highly-Concentrated Antibodies under the Acid-Treated Conditions
9. Impact of single-residue mutations on protein thermal stability: The case of threonine 83 of BC2L-CN lectin
10. Generation of antibodies to an extracellular region of the transporters Glut1/Glut4 by immunization with a designed antigen
11. Unveiling the structural mechanisms behind high affinity and selectivity in phosphorylated epitope-specific rabbit antibodies
12. High-throughput analysis system of interaction kinetics for data-driven antibody design
13. Specific peptide conjugation to a therapeutic antibody leads to enhanced therapeutic potency and thermal stability by reduced Fc dynamics
14. Discovery of a cystathionine γ-lyase (CSE) selective inhibitor targeting active-site pyridoxal 5′-phosphate (PLP) via Schiff base formation
15. Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection
16. Inactivation and spike protein denaturation of novel coronavirus variants by CuxO/TiO2 nano-photocatalysts
17. Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain
18. Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene
19. Safe and efficient oral allergy immunotherapy using one-pot-prepared mannan-coated allergen nanoparticles
20. Quantitative analysis of antibody aggregates by combination of pinched-flow fractionation and coulter method
21. One-pot preparation of mannan-coated antigen nanoparticles using human serum albumin as a matrix for tolerance induction
22. Ferguson plot analysis of multiple intermediate species of thermally unfolded bovine serum albumin
23. Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes
24. Targeting hemoglobin receptors IsdH and IsdB of Staphylococcus aureus with a single VHH antibody inhibits bacterial growth
25. Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
26. Agarose native gel electrophoresis analysis of thermal aggregation controlled by Hofmeister series
27. Bromodomain protein BRD8 regulates cell cycle progression in colorectal cancer cells through a TIP60-independent regulation of the pre-RC complex
28. Structural Classification of CDR-H3 in Single-Domain VHH Antibodies
29. Analytical Method for Experimental Validation of Computer-Designed Antibody
30. Analysis of bovine serum albumin unfolding in the absence and presence of ATP by SYPRO Orange staining of agarose native gel electrophoresis
31. Ladder observation of bovine serum albumin by high resolution agarose native gel electrophoresis
32. Addition of arginine hydrochloride and proline to the culture medium enhances recombinant protein expression in Brevibacillus choshinensis: The case of RBD of SARS-CoV-2 spike protein and its antibody
33. Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus
34. Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis
35. Triphenylphosphonium-modified catiomers enhance in vivo mRNA delivery through stabilized polyion complexation.
36. Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer
37. Mirror-image streptavidin with specific binding to L-biotin, the unnatural enantiomer
38. Extracellular matrix-inspired hydrogel of hyaluronan and gelatin crosslinked via a Link module with a transglutaminase reactive sequence
39. Human antibody recognition and neutralization mode on the NTD and RBD domains of SARS-CoV-2 spike protein
40. High‐throughput system for the thermostability analysis of proteins
41. Cryo-EM structures elucidate the multiligand receptor nature of megalin
42. Characterization of a novel format scFv×VHH single‐chain biparatopic antibody against metal binding protein MtsA
43. Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1
44. Systematic Preparation of a 66-IgG Library with Symmetric and Asymmetric Homogeneous Glycans and Their Functional Evaluation.
45. Unveiling the affinity–stability relationship in anti-measles virus antibodies: a computational approach for hotspots prediction
46. Anti-EGFR antibody 528 binds to domain III of EGFR at a site shifted from the cetuximab epitope
47. Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies
48. Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
49. A glutamine sensor that directly activates TORC1
50. Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support
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