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Your search keyword '"Vacchelli, Erika"' showing total 8 results
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8 results on '"Vacchelli, Erika"'

1. Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesis

Author

Le Naour, Julie, primary, Montégut, Léa, additional, Pan, Yuhong, additional, Scuderi, Sarah Adriana, additional, Cordier, Pierre, additional, Joseph, Adrien, additional, Sauvat, Allan, additional, Iebba, Valerio, additional, Paillet, Juliette, additional, Ferrere, Gladys, additional, Brechard, Ludivine, additional, Mulot, Claire, additional, Dubourg, Grégory, additional, Zitvogel, Laurence, additional, Pol, Jonathan G., additional, Vacchelli, Erika, additional, Puig, Pierre-Laurent, additional, and Kroemer, Guido, additional

Published
2023
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2. Table S4 from A TLR3 Ligand Reestablishes Chemotherapeutic Responses in the Context of FPR1 Deficiency

Author

Le Naour, Julie, primary, Liu, Peng, primary, Zhao, Liwei, primary, Adjemian, Sandy, primary, Sztupinszki, Zsofia, primary, Taieb, Julien, primary, Mulot, Claire, primary, Silvin, Aymeric, primary, Dutertre, Charles-Antoine, primary, Ginhoux, Florent, primary, Sauvat, Allan, primary, Cerrato, Giulia, primary, Castoldi, Francesca, primary, Martins, Isabelle, primary, Stoll, Gautier, primary, Paillet, Juliette, primary, Mangane, Khady, primary, Richter, Cornelia, primary, Kepp, Oliver, primary, Maiuri, Maria Chiara, primary, Pietrocola, Federico, primary, Vandenabeele, Peter, primary, André, Fabrice, primary, Delaloge, Suzette, primary, Szallasi, Zoltan, primary, Laurent-Puig, Pierre, primary, Zucman-Rossi, Jessica, primary, Zitvogel, Laurence, primary, Pol, Jonathan G., primary, Vacchelli, Erika, primary, and Kroemer, Guido, primary

Published
2023
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3. Supplementary Figures and Tables from A TLR3 Ligand Reestablishes Chemotherapeutic Responses in the Context of FPR1 Deficiency

Author

Le Naour, Julie, primary, Liu, Peng, primary, Zhao, Liwei, primary, Adjemian, Sandy, primary, Sztupinszki, Zsofia, primary, Taieb, Julien, primary, Mulot, Claire, primary, Silvin, Aymeric, primary, Dutertre, Charles-Antoine, primary, Ginhoux, Florent, primary, Sauvat, Allan, primary, Cerrato, Giulia, primary, Castoldi, Francesca, primary, Martins, Isabelle, primary, Stoll, Gautier, primary, Paillet, Juliette, primary, Mangane, Khady, primary, Richter, Cornelia, primary, Kepp, Oliver, primary, Maiuri, Maria Chiara, primary, Pietrocola, Federico, primary, Vandenabeele, Peter, primary, André, Fabrice, primary, Delaloge, Suzette, primary, Szallasi, Zoltan, primary, Laurent-Puig, Pierre, primary, Zucman-Rossi, Jessica, primary, Zitvogel, Laurence, primary, Pol, Jonathan G., primary, Vacchelli, Erika, primary, and Kroemer, Guido, primary

Published
2023
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4. Data from A TLR3 Ligand Reestablishes Chemotherapeutic Responses in the Context of FPR1 Deficiency

Author

Le Naour, Julie, primary, Liu, Peng, primary, Zhao, Liwei, primary, Adjemian, Sandy, primary, Sztupinszki, Zsofia, primary, Taieb, Julien, primary, Mulot, Claire, primary, Silvin, Aymeric, primary, Dutertre, Charles-Antoine, primary, Ginhoux, Florent, primary, Sauvat, Allan, primary, Cerrato, Giulia, primary, Castoldi, Francesca, primary, Martins, Isabelle, primary, Stoll, Gautier, primary, Paillet, Juliette, primary, Mangane, Khady, primary, Richter, Cornelia, primary, Kepp, Oliver, primary, Maiuri, Maria Chiara, primary, Pietrocola, Federico, primary, Vandenabeele, Peter, primary, André, Fabrice, primary, Delaloge, Suzette, primary, Szallasi, Zoltan, primary, Laurent-Puig, Pierre, primary, Zucman-Rossi, Jessica, primary, Zitvogel, Laurence, primary, Pol, Jonathan G., primary, Vacchelli, Erika, primary, and Kroemer, Guido, primary

Published
2023
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8. A loss-of-function polymorphism in ATG16L1compromises therapeutic outcome in head and neck carcinoma patients

Author

Le Naour, Julie, Sztupinszki, Zsofia, Carbonnier, Vincent, Casiraghi, Odile, Marty, Virginie, Galluzzi, Lorenzo, Szallasi, Zoltan, Kroemer, Guido, and Vacchelli, Erika

Abstract

ABSTRACTThe anticancer immune response is shaped by immunogenic cell stress and death pathways. Thus, cancer cells can release danger-associated molecular patterns that act on pattern recognition receptors expressed by dendritic cells and their precursors to elicit an antitumor immune response. Here, we investigated the impact of single nucleotide polymorphisms (SNPs) in genes affecting this cancer-immunity dialogue in the context of head and neck squamous cell carcinoma (HNSCC). We observed that homozygosity for a loss-of-function SNP (rs2241880, leading to the substitution of a threonine residue in position 300 by an alanine) affecting autophagy related 16 like 1 (ATG16L1)is coupled to poor progression-free survival in platinum-treated HNSCC patients. This result was obtained on a cohort of patients enrolled at the Gustave Roussy Cancer Campus and was validated on an independent cohort of The Cancer Genome Atlas (TCGA). Homozygosity in rs2241880 is well known to predispose to Crohn’s disease, and epidemiological associations between Crohn’s disease and HNSCC have been reported at the levels of cancer incidence and prognosis. We speculate that rs2241880 might be partially responsible for this association.

Published
2022
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