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44 results on '"Vernooij, Robin W.M."'

1. A health economic evaluation of the multinational, randomized controlled CONVINCE trial - cost-utility of high-dose online hemodiafiltration compared to high-flux hemodialysis.

Author

Bots, Michiel, Barth, Claudia, Blankestijn, Peter, Canaud, Bernard, Cromm, Krister, Davenport, Andrew, Fischer, Kathrin, Hegbrant, Jörgen, Rose, Matthias, Strippoli, Giovanni, Török, Mariëtta, Woodward, Mark, Schouten, Aniek E.M., Fischer, Felix, Blankestijn, Peter J., Vernooij, Robin W.M., Hockham, Carinna, Strippoli, Giovanni F.M., Fischer, Kathrin I., Bots, Michiel L., Ardine de Wit, G., Frederix, Geert W.J., and van der Meulen, Miriam P.

Published
2025
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2. The CONVINCE randomized trial found positive effects on quality of life for patients with chronic kidney disease treated with hemodiafiltration

Author

Rose, Matthias, Fischer, Felix H., Liegl, Gregor, Strippoli, Giovanni F.M., Hockham, Carina, Vernooij, Robin W.M., Barth, Claudia, Canaud, Bernard, Covic, Adrian, Cromm, Krister, Cucui, Andrea M., Davenport, Andrew, Fischer, Kathrin I., Hegbrant, Jörgen, Jaha, Hanna, Schappert, Anna, Török, Marietta, Woodward, Mark, Bots, Michiel L., and Blankestijn, Peter J.

Published
2024
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7. Risk of thrombosis and bleeding in gynecologic noncancer surgery: systematic review and meta-analysis

Author

Ahopelto, Kaisa, Aoki, Yoshitaka, Beilmann-Lehtonen, Ines, Blanker, Marco H., Craigie, Samantha, Elberkennou, Jaana, Garcia-Perdomo, Herney A., Gomaa, Huda A., Gross, BCPS; Peter, Hajebrahimi, Sakineh, Huang, Linglong, Karanicolas, Paul J., Kilpeläinen, Tuomas P., Kivelä, Antti J., Korhonen, Tapio, Lampela, Hanna, Lee, Yung, Mattila, Anne K., Najafabadi, Borna Tadayon, Nykänen, Taina P., Nystén, Carolina, Pandanaboyana, Sanjay, Ratnayake, Chathura B.B., Raudasoja, Aleksi R., Sallinen, Ville J., Violette, Philippe D., Xiao, Yingqi, Yao, Liang, Lavikainen, Lauri I., Guyatt, Gordon H., Kalliala, Ilkka E.J., Cartwright, Rufus, Luomaranta, Anna L., Vernooij, Robin W.M., Tähtinen, Riikka M., Tadayon Najafabadi, Borna, Singh, Tino, Pourjamal, Negar, Oksjoki, Sanna M., Khamani, Nadina, Karjalainen, Päivi K., Joronen, Kirsi M., Izett-Kay, Matthew L., Haukka, Jari, Halme, Alex L.E., Ge, Fang Zhou, Galambosi, Päivi J., Devereaux, P.J., Cárdenas, Jovita L., Couban, Rachel J., Aro, Karoliina M., Aaltonen, Riikka L., and Tikkinen, Kari A.O.

Published
2024
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8. Risk of thrombosis and bleeding in gynecologic cancer surgery: systematic review and meta-analysis

Author

Ahopelto, Kaisa, Aoki, Yoshitaka, Beilmann-Lehtonen, Ines, Blanker, Marco H., Craigie, Samantha, Elberkennou, Jaana, Garcia-Perdomo, Herney A., Gomaa, Huda A., Gross, Peter, Hajebrahimi, Sakineh, Karanicolas, Paul J., Kilpeläinen, Tuomas P., Kivelä, Antti J., Korhonen, Tapio, Lampela, Hanna, Lee, Yung, Mattila, Anne K., Najafabadi, Borna Tadayon, Nykänen, Taina P., Nystén, Carolina, Pandanaboyana, Sanjay, Ratnayake, Chathura B.B., Raudasoja, Aleksi R., Sallinen, Ville J., Violette, Philippe D., Xiao, Yingqi, Yao, Liang, Lavikainen, Lauri I., Guyatt, Gordon H., Luomaranta, Anna L., Cartwright, Rufus, Kalliala, Ilkka E.J., Couban, Rachel J., Aaltonen, Riikka L., Aro, Karoliina M., Cárdenas, Jovita L., Devereaux, P.J., Galambosi, Päivi J., Ge, Fang Zhou, Halme, Alex L.E., Haukka, Jari, Izett-Kay, Matthew L., Joronen, Kirsi M., Karjalainen, Päivi K., Khamani, Nadina, Oksjoki, Sanna M., Pourjamal, Negar, Singh, Tino, Tähtinen, Riikka M., Vernooij, Robin W.M., and Tikkinen, Kari A.O.

Published
2024
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9. Systematic Reviews and Meta-analyses of the Procedure-specific Risks of Thrombosis and Bleeding in General Abdominal, Colorectal, Upper Gastrointestinal, and Hepatopancreatobiliary Surgery

Author

Lavikainen, Lauri I., Guyatt, Gordon H., Sallinen, Ville J., Karanicolas, Paul J., Couban, Rachel J., Singh, Tino, Lee, Yung, Elberkennou, Jaana, Aaltonen, Riikka, Ahopelto, Kaisa, Beilmann-Lehtonen, Ines, Blanker, Marco H., Cárdenas, Jovita L., Cartwright, Rufus, Craigie, Samantha, Devereaux, P.J., Garcia-Perdomo, Herney A., Ge, Fang Zhou, Gomaa, Huda A., Halme, Alex L.E., Haukka, Jari, Karjalainen, Päivi K., Kilpeläinen, Tuomas P., Kivelä, Antti J., Lampela, Hanna, Mattila, Anne K., Najafabadi, Borna Tadayon, Nykänen, Taina P., Pandanaboyana, Sanjay, Pourjamal, Negar, Ratnayake, Chathura B.B., Raudasoja, Aleksi, Vernooij, Robin W.M., Violette, Philippe D., Wang, Yuting, Xiao, Yingqi, Yao, Liang, Tikkinen, Kari A. O., Aoki, Yoshitaka, Aro, Karoliina M., Galambosi, Päivi J., Gross, Peter, Hajebrahimi, Sakineh, Huang, Linglong, Izett-Kay, Matthew L., Joronen, Kirsi M., Kalliala, Ilkka E.J., Khamani, Nadina, Korhonen, Tapio, Luomaranta, Anna L., Nystén, Carolina, Oksjoki, Sanna M., and Tähtinen, Riikka M.

Published
2024
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15. The Effect of Artificial Intelligence on Patient-Physician Trust: Cross-Sectional Vignette Study

Author

Zondag, Anna G.M., Rozestraten, Raoul, Grimmelikhuijsen, Stephan G., Jongsma, Karin R., van Solinge, Wouter W., Bots, Michiel L., Vernooij, Robin W.M., Haitjema, Saskia, Zondag, Anna G.M., Rozestraten, Raoul, Grimmelikhuijsen, Stephan G., Jongsma, Karin R., van Solinge, Wouter W., Bots, Michiel L., Vernooij, Robin W.M., and Haitjema, Saskia

Abstract

BACKGROUND: Clinical decision support systems (CDSSs) based on routine care data, using artificial intelligence (AI), are increasingly being developed. Previous studies focused largely on the technical aspects of using AI, but the acceptability of these technologies by patients remains unclear. OBJECTIVE: We aimed to investigate whether patient-physician trust is affected when medical decision-making is supported by a CDSS. METHODS: We conducted a vignette study among the patient panel (N=860) of the University Medical Center Utrecht, the Netherlands. Patients were randomly assigned into 4 groups-either the intervention or control groups of the high-risk or low-risk cases. In both the high-risk and low-risk case groups, a physician made a treatment decision with (intervention groups) or without (control groups) the support of a CDSS. Using a questionnaire with a 7-point Likert scale, with 1 indicating "strongly disagree" and 7 indicating "strongly agree," we collected data on patient-physician trust in 3 dimensions: competence, integrity, and benevolence. We assessed differences in patient-physician trust between the control and intervention groups per case using Mann-Whitney U tests and potential effect modification by the participant's sex, age, education level, general trust in health care, and general trust in technology using multivariate analyses of (co)variance. RESULTS: In total, 398 patients participated. In the high-risk case, median perceived competence and integrity were lower in the intervention group compared to the control group but not statistically significant (5.8 vs 5.6; P=.16 and 6.3 vs 6.0; P=.06, respectively). However, the effect of a CDSS application on the perceived competence of the physician depended on the participant's sex (P=.03). Although no between-group differences were found in men, in women, the perception of the physician's competence and integrity was significantly lower in the intervention compared to the control group (P=.00

Published
2024

16. Risk of thrombosis and bleeding in gynecologic cancer surgery: systematic review and meta-analysis

Author

MS Nefrologie, Lavikainen, Lauri I., Guyatt, Gordon H., Kalliala, Ilkka E.J., Cartwright, Rufus, Luomaranta, Anna L., Vernooij, Robin W.M., Tähtinen, Riikka M., Najafabadi, Borna Tadayon, Singh, Tino, ROTBIGGS Investigators, MS Nefrologie, Lavikainen, Lauri I., Guyatt, Gordon H., Kalliala, Ilkka E.J., Cartwright, Rufus, Luomaranta, Anna L., Vernooij, Robin W.M., Tähtinen, Riikka M., Najafabadi, Borna Tadayon, Singh, Tino, and ROTBIGGS Investigators

Published
2024

17. Systematic Reviews and Meta-Analyses of the Procedure-specific Risks of Thrombosis and Bleeding in General Abdominal, Colorectal, Upper Gastrointestinal, and Hepatopancreatobiliary Surgery

Author

MS Nefrologie, Lavikainen, Lauri I., Guyatt, Gordon H., Sallinen, Ville J., Karanicolas, Paul J., Couban, Rachel J., Singh, Tino, Lee, Yung, Elberkennou, Jaana, Aaltonen, Riikka, Ahopelto, Kaisa, Beilmann-Lehtonen, Ines, Blanker, Marco H., Cárdenas, Jovita L., Cartwright, Rufus, Craigie, Samantha, Devereaux, P. J., Garcia-Perdomo, Herney A., Ge, Fang Zhou, Gomaa, Huda A., Halme, Alex L.E., Haukka, Jari, Karjalainen, Päivi K., Kilpeläinen, Tuomas P., Kivelä, Antti J., Lampela, Hanna, Mattila, Anne K., Najafabadi, Borna Tadayon, Nykänen, Taina P., Pandanaboyana, Sanjay, Pourjamal, Negar, Ratnayake, Chathura B.B., Raudasoja, Aleksi, Vernooij, Robin W.M., Violette, Philippe D., Wang, Yuting, Xiao, Yingqi, Yao, Liang, Tikkinen, Kari A.O., MS Nefrologie, Lavikainen, Lauri I., Guyatt, Gordon H., Sallinen, Ville J., Karanicolas, Paul J., Couban, Rachel J., Singh, Tino, Lee, Yung, Elberkennou, Jaana, Aaltonen, Riikka, Ahopelto, Kaisa, Beilmann-Lehtonen, Ines, Blanker, Marco H., Cárdenas, Jovita L., Cartwright, Rufus, Craigie, Samantha, Devereaux, P. J., Garcia-Perdomo, Herney A., Ge, Fang Zhou, Gomaa, Huda A., Halme, Alex L.E., Haukka, Jari, Karjalainen, Päivi K., Kilpeläinen, Tuomas P., Kivelä, Antti J., Lampela, Hanna, Mattila, Anne K., Najafabadi, Borna Tadayon, Nykänen, Taina P., Pandanaboyana, Sanjay, Pourjamal, Negar, Ratnayake, Chathura B.B., Raudasoja, Aleksi, Vernooij, Robin W.M., Violette, Philippe D., Wang, Yuting, Xiao, Yingqi, Yao, Liang, and Tikkinen, Kari A.O.

Published
2024

20. Risk of kidney and liver diseases after COVID-19 infection: A systematic review and meta-analysis

Author

MS Nefrologie, Pan, Bei, Wang, Xiaoman, Lai, Honghao, Vernooij, Robin W.M., Deng, Xiyuan, Ma, Ning, Li, Dan, Huang, Jiajie, Zhao, Weilong, Ning, Jinling, Liu, Jianing, Tian, Jinhui, Ge, Long, Yang, Kehu, MS Nefrologie, Pan, Bei, Wang, Xiaoman, Lai, Honghao, Vernooij, Robin W.M., Deng, Xiyuan, Ma, Ning, Li, Dan, Huang, Jiajie, Zhao, Weilong, Ning, Jinling, Liu, Jianing, Tian, Jinhui, Ge, Long, and Yang, Kehu

Published
2024

21. Left Ventricular Diastolic Dysfunction across Levels of Kidney Function: A Cross-Sectional Study Based on Routine Clinical Practice Data

Author

Circulatory Health, Experimentele Afd. Cardiologie 1, Experimental Cardiology Laboratory, CDL Poli WKZ, CDL Cluster Speciële Diagnostiek, CDL Upod, Other research (not in main researchprogram), Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Cardiovascular Health, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, MS Nefrologie, Porras, Cindy P., Dal Canto, Elisa, van Ommen, Anne Mar L., Handoko, M. Louis, Haitjema, Saskia, de Groot, Mark C.H., Bots, Michiel L., Verhaar, Marianne C., Vernooij, Robin W.M., Circulatory Health, Experimentele Afd. Cardiologie 1, Experimental Cardiology Laboratory, CDL Poli WKZ, CDL Cluster Speciële Diagnostiek, CDL Upod, Other research (not in main researchprogram), Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Cardiovascular Health, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, MS Nefrologie, Porras, Cindy P., Dal Canto, Elisa, van Ommen, Anne Mar L., Handoko, M. Louis, Haitjema, Saskia, de Groot, Mark C.H., Bots, Michiel L., Verhaar, Marianne C., and Vernooij, Robin W.M.

Published
2024

22. Risk of Thrombosis and Bleeding in Gynecologic Non-Cancer Surgery: Systematic Review and Meta-Analysis

Author

Lavikainen, Lauri I., primary, Guyatt, Gordon H., additional, Kalliala, Ilkka E.J., additional, Cartwright, Rufus, additional, Luomaranta, Anna L., additional, Vernooij, Robin W.M., additional, Tähtinen, Riikka M., additional, Najafabadi, Borna Tadayon, additional, Singh, Tino, additional, Pourjamal, Negar, additional, Oksjoki, Sanna M., additional, Khamani, Nadina, additional, Karjalainen, Päivi K., additional, Joronen, Kirsi M., additional, Izett-Kay, Matthew L., additional, Haukka, Jari, additional, Halme, Alex L.E., additional, Ge, Fang Zhou, additional, Galambosi, Päivi J., additional, Devereaux, P.J., additional, Cárdenas, Jovita L., additional, Couban, Rachel J., additional, Aro, Karoliina M., additional, Aaltonen, Riikka L., additional, Tikkinen, Kari A.O., additional, Ahopelto, Kaisa, additional, Aoki, Yoshitaka, additional, Beilmann-Lehtonen, Ines, additional, Blanker, Marco H., additional, Craigie, Samantha, additional, Elberkennou, Jaana, additional, Garcia-Perdomo, Herney A., additional, Gomaa, Huda A., additional, Gross, Peter, additional, Hajebrahimi, Sakineh, additional, Huang, Linglong, additional, Karanicolas, Paul J., additional, Kilpeläinen, Tuomas P., additional, Kivelä, Antti J., additional, Korhonen, Tapio, additional, Lampela, Hanna, additional, Lee, Yung, additional, Mattila, Anne K., additional, Nykänen, Taina P., additional, Nystén, Carolina, additional, Pandanaboyana, Sanjay, additional, Ratnayake, Chathura B.B., additional, Raudasoja, Aleksi R., additional, Sallinen, Ville J., additional, Violette, Philippe D., additional, Xiao, Yingqi, additional, and Yao, Liang, additional

Published
2023
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24. Risk of Thrombosis and Bleeding in Gynecologic Cancer Surgery: Systematic Review and Meta-Analysis

Author

Lavikainen, Lauri I., primary, Guyatt, Gordon H., additional, Luomaranta, Anna L., additional, Cartwright, Rufus, additional, Kalliala, Ilkka E.J., additional, Couban, Rachel J., additional, Aaltonen, Riikka L., additional, Aro, Karoliina M., additional, Cárdenas, Jovita L., additional, Devereaux, P.J., additional, Galambosi, Päivi J., additional, Ge, Fang Zhou, additional, Halme, Alex L.E., additional, Haukka, Jari, additional, Izett-Kay, Matthew L., additional, Joronen, Kirsi M., additional, Karjalainen, Päivi K., additional, Khamani, Nadina, additional, Oksjoki, Sanna M., additional, Pourjamal, Negar, additional, Singh, Tino, additional, Tähtinen, Riikka M., additional, Vernooij, Robin W.M., additional, and Tikkinen, Kari A.O., additional

Published
2023
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25. Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure

Author

Blankestijn, Peter J., primary, Vernooij, Robin W.M., additional, Hockham, Carinna, additional, Strippoli, Giovanni F.M., additional, Canaud, Bernard, additional, Hegbrant, Jörgen, additional, Barth, Claudia, additional, Covic, Adrian, additional, Cromm, Krister, additional, Cucui, Andrea, additional, Davenport, Andrew, additional, Rose, Matthias, additional, Török, Marietta, additional, Woodward, Mark, additional, and Bots, Michiel L., additional

Published
2023
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26. Risk of thrombosis and bleeding in gynecologic noncancer surgery: systematic review and meta-analysis.

Author

Lavikainen, Lauri I., Guyatt, Gordon H., Kalliala, Ilkka E.J., Cartwright, Rufus, Luomaranta, Anna L., Vernooij, Robin W.M., Tähtinen, Riikka M., Tadayon Najafabadi, Borna, Singh, Tino, Pourjamal, Negar, Oksjoki, Sanna M., Khamani, Nadina, Karjalainen, Päivi K., Joronen, Kirsi M., Izett-Kay, Matthew L., Haukka, Jari, Halme, Alex L.E., Ge, Fang Zhou, Galambosi, Päivi J., and Devereaux, P.J.

Subjects
GYNECOLOGIC surgery, VENOUS thrombosis, THROMBOEMBOLISM, THROMBOSIS, HEMORRHAGE, OOCYTE retrieval
Abstract

This study aimed to provide procedure-specific estimates of the risk for symptomatic venous thromboembolism and major bleeding in noncancer gynecologic surgeries. We conducted comprehensive searches on Embase, MEDLINE, Web of Science, and Google Scholar. Furthermore, we performed separate searches for randomized trials that addressed the effects of thromboprophylaxis. Eligible studies were observational studies that enrolled ≥50 adult patients who underwent noncancer gynecologic surgery procedures and that reported the absolute incidence of at least 1 of the following: symptomatic pulmonary embolism, symptomatic deep vein thrombosis, symptomatic venous thromboembolism, bleeding that required reintervention (including re-exploration and angioembolization), bleeding that led to transfusion, or postoperative hemoglobin level <70 g/L. A teams of 2 reviewers independently assessed eligibility, performed data extraction, and evaluated the risk of bias of the eligible articles. We adjusted the reported estimates for thromboprophylaxis and length of follow-up and used the median value from studies to determine the cumulative incidence at 4 weeks postsurgery stratified by patient venous thromboembolism risk factors and used the Grading of Recommendations Assessment, Development and Evaluation approach to rate the evidence certainty. We included 131 studies (1,741,519 patients) that reported venous thromboembolism risk estimates for 50 gynecologic noncancer procedures and bleeding requiring reintervention estimates for 35 procedures. The evidence certainty was generally moderate or low for venous thromboembolism and low or very low for bleeding requiring reintervention. The risk for symptomatic venous thromboembolism varied from a median of <0.1% for several procedures (eg, transvaginal oocyte retrieval) to 1.5% for others (eg, minimally invasive sacrocolpopexy with hysterectomy, 1.2%–4.6% across patient venous thromboembolism risk groups). Venous thromboembolism risk was <0.5% for 30 (60%) of the procedures; 0.5% to 1.0% for 10 (20%) procedures; and >1.0% for 10 (20%) procedures. The risk for bleeding the require reintervention varied from <0.1% (transvaginal oocyte retrieval) to 4.0% (open myomectomy). The bleeding requiring reintervention risk was <0.5% in 17 (49%) procedures, 0.5% to 1.0% for 12 (34%) procedures, and >1.0% in 6 (17%) procedures. The risk for venous thromboembolism in gynecologic noncancer surgery varied between procedures and patients. Venous thromboembolism risks exceeded the bleeding risks only among selected patients and procedures. Although most of the evidence is of low certainty, the results nevertheless provide a compelling rationale for restricting pharmacologic thromboprophylaxis to a minority of patients who undergo gynecologic noncancer procedures. [ABSTRACT FROM AUTHOR]

Published
2024
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27. The persistent underrepresentation of patients with chronic kidney disease in cardiovascular trials: a systematic review and evidence map of exclusion and outcomes

Author

Colombijn, Julia M.T., primary, Idema, Demy L., additional, van Beem, Sanne, additional, Blokland, Anna Marthe, additional, van der Braak, Kim, additional, Handoko, M. Louis, additional, Huis in't Veld, Linde F., additional, Kaul, Tabea, additional, Kolagasigil-Akdemir, Nurda, additional, Kusters, Mike P.T., additional, Meijvis, Sabine C.A., additional, Oosting, Ilse J., additional, Spijker, René, additional, Bots, Michiel, additional, Hooft, Lotty, additional, Verhaar, Marianne C., additional, and Vernooij, Robin W.M., additional

Published
2023
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28. Animal Models for Studying Protein-Bound Uremic Toxin Removal—A Systematic Review

Author

MS Nefrologie, Circulatory Health, Regenerative Medicine and Stem Cells, Ahmed, Sabbir, de Vries, Joost C., Lu, Jingyi, Stuart, Milan H.Verrijn, Mihăilă, Silvia M., Vernooij, Robin W.M., Masereeuw, Rosalinde, Gerritsen, Karin G.F., MS Nefrologie, Circulatory Health, Regenerative Medicine and Stem Cells, Ahmed, Sabbir, de Vries, Joost C., Lu, Jingyi, Stuart, Milan H.Verrijn, Mihăilă, Silvia M., Vernooij, Robin W.M., Masereeuw, Rosalinde, and Gerritsen, Karin G.F.

Published
2023

30. Discovering Distinct Phenotypical Clusters in Heart Failure Across the Ejection Fraction Spectrum:a Systematic Review

Author

Meijs, Claartje, Handoko, M. Louis, Savarese, Gianluigi, Vernooij, Robin W.M., Vaartjes, Ilonca, Banerjee, Amitava, Koudstaal, Stefan, Brugts, Jasper J., Asselbergs, Folkert W., Uijl, Alicia, Meijs, Claartje, Handoko, M. Louis, Savarese, Gianluigi, Vernooij, Robin W.M., Vaartjes, Ilonca, Banerjee, Amitava, Koudstaal, Stefan, Brugts, Jasper J., Asselbergs, Folkert W., and Uijl, Alicia

Abstract

Review Purpose: This systematic review aims to summarise clustering studies in heart failure (HF) and guide future clinical trial design and implementation in routine clinical practice. Findings: 34 studies were identified (n = 19 in HF with preserved ejection fraction (HFpEF)). There was significant heterogeneity invariables and techniques used. However, 149/165 described clusters could be assigned to one of nine phenotypes: 1) young, low comorbidity burden; 2) metabolic; 3) cardio-renal; 4) atrial fibrillation (AF); 5) elderly female AF; 6) hypertensive-comorbidity; 7) ischaemic-male; 8) valvular disease; and 9) devices. There was room for improvement on important methodological topics for all clustering studies such as external validation and transparency of the modelling process.Summary:The large overlap between the phenotypes of the clustering studies shows that clustering is a robust approach for discovering clinically distinct phenotypes. However, future studies should invest in a phenotype model that can be implemented in routine clinical practice and future clinical trial design. Graphical Abstract: HF = heart failure, EF = ejection fraction, HFpEF = heart failure with preserved ejection fraction, HFrEF = heart failure with reduced ejection fraction, CKD = chronic kidney disease, AF = atrial fibrillation, IHD = ischaemic heart disease, CAD = coronary artery disease, ICD = implantable cardioverter-defibrillator, CRT = cardiac resynchronization therapy, NT-proBNP = N-terminal pro b-type natriuretic peptide, BMI = Body Mass Index, COPD = Chronic obstructive pulmonary disease. [Figure not available: see fulltext.]

Published
2023

31. High-Target Hemodiafiltration Convective Dose Achieved in Most Patients in a 6-Month Intermediary Analysis of the CONVINCE Randomized Controlled Trial

Author

MS Nefrologie, Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Nefro Vasculaire Geneeskunde, Vernooij, Robin W.M., Hockham, C., Barth, C., Canaud, B., Cromm, K., Davenport, A., Hegbrant, J., Rose, M., Strippoli, G. F.M., Török, M., Woodward, M., Bots, M. L., Blankestijn, P. J., MS Nefrologie, Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Nefro Vasculaire Geneeskunde, Vernooij, Robin W.M., Hockham, C., Barth, C., Canaud, B., Cromm, K., Davenport, A., Hegbrant, J., Rose, M., Strippoli, G. F.M., Török, M., Woodward, M., Bots, M. L., and Blankestijn, P. J.

Published
2023

32. Prediction of disease specific and overall survival in men with prostate cancer using the Decipher assay

Author

MS Nefrologie, Julius Centrum, Epi Methoden Team 5, Garegnani, Luis, Franco, Juan V.A., Melendi, Santiago E., Vernooij, Robin W.M., Jung, Jae Hung, Hwang, Eu Chang, Damen, Johanna A.A.G., Warlick, Christopher A., Coles, Bernadette, Dahm, Philipp, MS Nefrologie, Julius Centrum, Epi Methoden Team 5, Garegnani, Luis, Franco, Juan V.A., Melendi, Santiago E., Vernooij, Robin W.M., Jung, Jae Hung, Hwang, Eu Chang, Damen, Johanna A.A.G., Warlick, Christopher A., Coles, Bernadette, and Dahm, Philipp

Published
2023

34. Protocol for a Series of Systematic Reviews and Network Meta-analyses of Randomized Controlled Trials of Medications for Patients with Overactive Bladder Symptoms

Author

Agarwal, Arnav, Aoki, Yoshitaka, Bauer, Scott R., Bhatnagar, Neera, Bolsunovskyi, Kostiantyn, te Brummelstroete, Gerhard H., Cárdenas, Jovita L., Cartwright, Rufus, Elterman, Dean, Eryuzlu, Leyla, Gaudel, Pramila, Gutschon, Rachel E., Griebling, Tomas L., Hallamies, Sanna K., Heikkilä, Katriina, Izhar, Zain, Kilpeläinen, Tuomas P., Khurshid, Saqib, Laakkonen, Sanna M., Lee, Yung, Lopes, Luciane C., Loohuis, Anne, Mendieta, Alexander, Mynttinen, Henri, Salehi-Pourmehr, Hanieh, Pryalukhin, Alexey, Przydacz, Mikolaj, Siddiqui, Fahad J., Tähtinen, Riikka, Vernooij, Robin W.M., Violette, Philippe D., Witte, Lambertus P.W., Yoshimura, Koji, van der Worp, Henk, Puerto Nino, Angie K., Blanker, Marco H., Brignardello-Petersen, Romina, Guyatt, Gordon H., and Tikkinen, Kari A.O.

Published
2024
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35. Randomized controlled trials in de-implementation research : a systematic scoping review

Author

Raudasoja, Aleksi J., Falkenbach, Petra, Vernooij, Robin W.M., Mustonen, Jussi M.J., Agarwal, Arnav, Aoki, Yoshitaka, Blanker, Marco H., Cartwright, Rufus, Garcia-Perdomo, Herney A., Kilpeläinen, Tuomas P., Lainiala, Olli, Lamberg, Tiina, Nevalainen, Olli P.O., Raittio, Eero, Richard, Patrick O., Violette, Philippe D., Komulainen, Jorma, Sipilä, Raija, Tikkinen, Kari A.O., Faculty of Medicine, University of Helsinki, Department of Surgery, HUS Abdominal Center, Urologian yksikkö, Clinicum, South Carelia Social and Health care District Eksote, Tampere University, Department of Radiology, Clinical Medicine, and Tays Research Services

Subjects
Trial design, Scoping review, CHALLENGES, Cluster randomized trial, RESPIRATORY-TRACT INFECTIONS, CLUSTER, 3126 Surgery, anesthesiology, intensive care, radiology, Low-value care, 3141 Health care science, Clinical trials, Randomized controlled trial, Overuse, De-implementation, Methods
Abstract

Background: Healthcare costs are rising, and a substantial proportion of medical care is of little value. De-implementation of low-value practices is important for improving overall health outcomes and reducing costs. We aimed to identify and synthesize randomized controlled trials (RCTs) on de-implementation interventions and to provide guidance to improve future research. Methods: MEDLINE and Scopus up to May 24, 2021, for individual and cluster RCTs comparing de-implementation interventions to usual care, another intervention, or placebo. We applied independent duplicate assessment of eligibility, study characteristics, outcomes, intervention categories, implementation theories, and risk of bias. Results: Of the 227 eligible trials, 145 (64%) were cluster randomized trials (median 24 clusters; median follow-up time 305 days), and 82 (36%) were individually randomized trials (median follow-up time 274 days). Of the trials, 118 (52%) were published after 2010, 149 (66%) were conducted in a primary care setting, 163 (72%) aimed to reduce the use of drug treatment, 194 (85%) measured the total volume of care, and 64 (28%) low-value care use as outcomes. Of the trials, 48 (21%) described a theoretical basis for the intervention, and 40 (18%) had the study tailored by context-specific factors. Of the de-implementation interventions, 193 (85%) were targeted at physicians, 115 (51%) tested educational sessions, and 152 (67%) multicomponent interventions. Missing data led to high risk of bias in 137 (60%) trials, followed by baseline imbalances in 99 (44%), and deficiencies in allocation concealment in 56 (25%). Conclusions: De-implementation trials were mainly conducted in primary care and typically aimed to reduce low-value drug treatments. Limitations of current de-implementation research may have led to unreliable effect estimates and decreased clinical applicability of studied de-implementation strategies. We identified potential research gaps, including de-implementation in secondary and tertiary care settings, and interventions targeted at other than physicians. Future trials could be improved by favoring simpler intervention designs, better control of potential confounders, larger number of clusters in cluster trials, considering context-specific factors when planning the intervention (tailoring), and using a theoretical basis in intervention design. Registration: OSF Open Science Framework hk4b2. publishedVersion

Published
2022

36. The Effectiveness of Liu Zi Jue Exercise for Chronic Obstructive Pulmonary Disease (COPD): Systematic Review and Meta-analysis of Randomized Controlled Trials

Author

Fan, Mohan, primary, Vernooij, Robin W.M., additional, Fu, Zhanju, additional, Shao, Baoyi, additional, Li, Jiaqi, additional, Yang, Huaxi, additional, Wang, Eryu, additional, Qiu, Linjing, additional, Wang, Lei, additional, Lao, Lixing, additional, Liu, Jianping, additional, and Zhang, Ying, additional

Published
2022
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37. Quality assessment of Clinical Practice Guidelines (CPG) for the diagnosis and treatment of Inflammatory Bowel Disease using the AGREE II instrument: A Systematic Review.

Author

Zambrano-Sánchez, Renato, primary, Alvarez-Mena, Paulina, additional, Hidalgo, Diego, additional, Liquitay, Camila Micaela Escobar, additional, Franco, Juan.V.A., additional, Vernooij, Robin W.M., additional, Simancas-Racines, Daniel, additional, Viteri-García, Andrés, additional, and Montesinos-Guevara, Camila, additional

Published
2022
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39. Personalizing treatment in end-stage kidney disease: deciding between haemodiafiltration and haemodialysis based on individualized treatment effect prediction

Author

Kruijsdijk, R.C.M. van, Vernooij, Robin W.M., Bots, Michiel L., Peters, Sanne A.E., Dorresteijn, Jannick A.N., Visseren, Frank L.J., Blankestijn, Peter J., Debray, Thomas P.A., Kruijsdijk, R.C.M. van, Vernooij, Robin W.M., Bots, Michiel L., Peters, Sanne A.E., Dorresteijn, Jannick A.N., Visseren, Frank L.J., Blankestijn, Peter J., and Debray, Thomas P.A.

Abstract

Item does not contain fulltext

Published
2022

40. Evidence for pharmacological interventions to reduce cardiovascular risk for patients with chronic kidney disease: a study protocol of an evidence map

Author

MS Nefrologie, Team 5a, Epi Methoden Team 5, Circulatory Health, Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Epidemiology & Health Economics, JC onderzoeksprogramma Methodologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, Colombijn, Julia M.T., Idema, Demy L., van der Braak, Kim, Spijker, Rene, Meijvis, Sabine C.A., Bots, Michiel L., Hooft, Lotty, Verhaar, Marianne C., Vernooij, Robin W.M., MS Nefrologie, Team 5a, Epi Methoden Team 5, Circulatory Health, Cardiovasculaire Epi Team 5, Cardiovasculaire Epidemiologie, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Epidemiology & Health Economics, JC onderzoeksprogramma Methodologie, Nefro Vasculaire Geneeskunde, Regenerative Medicine and Stem Cells, Colombijn, Julia M.T., Idema, Demy L., van der Braak, Kim, Spijker, Rene, Meijvis, Sabine C.A., Bots, Michiel L., Hooft, Lotty, Verhaar, Marianne C., and Vernooij, Robin W.M.

Published
2022

41. A Reporting Tool for Adapted Guidelines in Health Care: The RIGHT-Ad@pt Checklist.

Author

Song, Yang, Alonso-Coello, Pablo, Ballesteros, Monica, Cluzeau, Francoise, Vernooij, Robin W.M., Arayssi, Thurayya, Bhaumik, Soumyadeep, Chen, Yaolong, Ghersi, Davina, Langlois, Etienne V., Fuentes Padilla, Paulina, Schünemann, Holger J., Akl, Elie A., Martínez García, Laura, Amer, Yasser, Arevalo-Rodriguez, Ingrid, Barnes, Steven, Barreto, Jorge, Collis, Deborah, and Dyer, Suzanne

Abstract

Background: Adaptation of existing guidelines can be an efficient way to develop contextualized recommendations. Transparent reporting of the adaptation approach can support the transparency and usability of the adapted guidelines.Objective: To develop an extension of the RIGHT (Reporting Items for practice Guidelines in HealThcare) statement for the reporting of adapted guidelines (including recommendations that have been adopted, adapted, or developed de novo), the RIGHT-Ad@pt checklist.Design: A multistep process was followed to develop the checklist: establishing a working group, generating an initial checklist, optimizing the checklist (through an initial assessment of adapted guidelines, semistructured interviews, a Delphi consensus survey, an external review, and a final assessment of adapted guidelines), and approval of the final checklist by the working group.Setting: International collaboration.Participants: A total of 119 professionals participated in the development process.Measurements: Participants' consensus on items in the checklist.Results: The RIGHT-Ad@pt checklist contains 34 items grouped in 7 sections: basic information (7 items); scope (6 items); rigor of development (10 items); recommendations (4 items); external review and quality assurance (2 items); funding, declaration, and management of interest (2 items); and other information (3 items). A user guide with explanations and real-world examples for each item was developed to provide a better user experience.Limitation: The RIGHT-Ad@pt checklist requires further validation in real-life use.Conclusion: The RIGHT-Ad@pt checklist has been developed to improve the reporting of adapted guidelines, focusing on the standardization, rigor, and transparency of the process and the clarity and explicitness of adapted recommendations.Primary Funding Source: None. [ABSTRACT FROM AUTHOR]

Published
2022
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44. Cost Utility of High-Dose Online Hemodiafiltration Compared with High-Flux Hemodialysis: Economic Evaluation of the Multinational, Randomized Controlled CONVINCE Trial

Author

Schouten, Aniek E.M., Fischer, Felix, Blankestijn, Peter J., Vernooij, Robin W.m., Hockham, Carinna, Strippoli, Giovanni, Canaud, Bernard J., Hegbrant, Jorgen BA, Barth, Claudia Maria, Cromm, Krister, Davenport, Andrew, Rose, Matthias, Woodward, Mark, Bots, Michiel L., de Wit, G. Ardine, Frederix, Geert, and van der Meulen, Miriam P

Published
2024
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