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Your search keyword '"Vertuani, Silvia"' showing total 24 results
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24 results on '"Vertuani, Silvia"'

2. A case of severe benzalkonium chloride intoxication in a cat

Author

Rubini, Silva, primary, Rubini, Roberto, additional, Bertocchi, Silvia, additional, Zordan, Silvia, additional, Magri, Alice, additional, Barsi, Filippo, additional, Sampieri, Maria, additional, Locatelli, Carlo Alessandro, additional, Baldini, Erika, additional, Manfredini, Stefano, additional, and Vertuani, Silvia, additional

Published
2024
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4. First Report of Pinnatoxin-G (PnTX-G) in a Marine–Coastal Area of the Adriatic Sea Associated with the Presence of the Dinoflagellate Vulcanodinium rugosum

Author

Cangini, Monica, primary, Dall’Ara, Sonia, additional, Rubini, Silva, additional, Bertasi, Barbara, additional, Rizzi, Paolo, additional, Dell’Orfano, Giovanni, additional, Milandri, Stefania, additional, Manfredini, Stefano, additional, Baldini, Erika, additional, and Vertuani, Silvia, additional

Published
2024
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5. 2G-lactic acid from olive oil supply chain waste: olive leaves upcycling via Lactobacillus casei fermentation.

Author

Gugel, Irene, Marchetti, Filippo, Costa, Stefania, Gugel, Ilenia, Baldini, Erika, Vertuani, Silvia, and Manfredini, Stefano

Subjects
LACTIC acid, OLIVE leaves, LACTOBACILLUS casei, OLIVE oil, OLIVE oil industry, CIRCULAR economy
Abstract

The transition towards a sustainable model, particularly the circular economy, emphasizes the importance of redefining waste as a valuable resource, paving the way for innovative upcycling strategies. The olive oil industry, with its significant output of agricultural waste, offers a promising avenue for high-value biomass conversion into useful products through microbial processes. This study focuses on exploring new, high-value applications for olive leaves waste, utilizing a biotechnological approach with Lactobacillus casei for the production of second-generation lactic acid. Contrary to initial expectations, the inherent high polyphenol content and low fermentable glucose levels in olive leaves posed challenges for fermentation. Addressing this, an enzymatic hydrolysis step, following a preliminary extraction process, was implemented to increase glucose availability. Subsequent small-scale fermentation tests were conducted with and without nutrient supplements, identifying the medium that yielded the highest lactic acid production for scale-up. The scaled-up batch fermentation process achieved an enhanced conversion rate (83.58%) and specific productivity (0.26 g/L·h). This research confirms the feasibility of repurposing olive waste leaves for the production of lactic acid, contributing to the advancement of a greener economy through the valorization of agricultural waste. Key points: • Olive leaves slurry as it did not allow L. casei to ferment. • High concentrations of polyphenols inhibit fermentation of L. casei. • Enzymatic hydrolysis combined to organosolv extraction is the best pretreatment for lactic acid production starting from leaves and olive pruning waste. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Fed-Batch Bioreactor Cultivation of Bacillus subtilis Using Vegetable Juice as an Alternative Carbon Source for Lipopeptides Production: A Shift towards a Circular Bioeconomy.

Author

Gugel, Irene, Vahidinasab, Maliheh, Benatto Perino, Elvio Henrique, Hiller, Eric, Marchetti, Filippo, Costa, Stefania, Pfannstiel, Jens, Konnerth, Philipp, Vertuani, Silvia, Manfredini, Stefano, and Hausmann, Rudolf

Subjects
VEGETABLE juices, SUSTAINABLE development, BACILLUS subtilis, AGRICULTURAL wastes, FOOD waste, SHIFTING cultivation
Abstract

In a scenario of increasing alarm about food waste due to rapid urbanization, population growth and lifestyle changes, this study aims to explore the valorization of waste from the retail sector as potential substrates for the biotechnological production of biosurfactants. With a perspective of increasingly contributing to the realization of the circular bioeconomy, a vegetable juice, derived from unsold fruits and vegetables, as a carbon source was used to produce lipopeptides such as surfactin and fengycin. The results from the shake flask cultivations revealed that different concentrations of vegetable juice could effectively serve as carbon sources and that the fed-batch bioreactor cultivation strategy allowed the yields of lipopeptides to be significantly increased. In particular, the product/substrate yield of 0.09 g/g for surfactin and 0.85 mg/g for fengycin was obtained with maximum concentrations of 2.77 g/L and 27.53 mg/L after 16 h, respectively. To conclude, this study provides the successful fed-batch cultivation of B. subtilis using waste product as the carbon source to produce secondary metabolites. Therefore, the consumption of agricultural product wastes might be a promising source for producing valuable metabolites which have promising application potential to be used in several fields of biological controls of fungal diseases. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Chemical Composition and Anti-Candida Activity of Mentha suaveolens Ehrh. Essential Oils Obtained by Different Distillation Processes

Author

Tadić, Vanja, primary, Božović, Mijat, additional, Sapienza, Filippo, additional, Astolfi, Roberta, additional, Mladenović, Milan, additional, Zaka, Maria Cristina, additional, Del Bove, Fabiana, additional, Borzacchi, Francesca, additional, Fraschetti, Caterina, additional, Rossi, Caterina, additional, Vertuani, Silvia, additional, Baldisserotto, Anna, additional, Manfredini, Stefano, additional, and Ragno, Rino, additional

Published
2023
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8. Mycoremediation of Synthetic Azo Dyes by White-Rot Fungi Grown on Diary Waste: A Step toward Sustainable and Circular Bioeconomy.

Author

Gugel, Irene, Summa, Daniela, Costa, Stefania, Manfredini, Stefano, Vertuani, Silvia, Marchetti, Filippo, and Tamburini, Elena

Subjects
FUNGAL remediation, SUSTAINABLE development, MANGANESE peroxidase, AZO dyes, DAIRY waste, ENDOCRINE disruptors, LIGNIN structure, COLOR removal (Sewage purification)
Abstract

This study assesses the efficacy of three white-rot fungi—Bjerkandera adusta, Phanerochaete chrysosporium, and Trametes versicolor—in degrading synthetic dyes and lignin in pulp and paper mill effluents, which annually contribute around 40,000 million cubic meters of dyed waste. Exploiting the structural resemblance of dyes to lignin, the fungi utilize ligninolytic enzymes—lignin peroxidase, manganese peroxidase, and laccase—to break down the pollutants. Initial mycoremediation trials in synthetic dye solutions with Direct black 80, Direct yellow 11, Basic brown 1, Orange II, and Red 8 BLP achieved decolorization rates of 70–80% within 7 days, except for Red 8 BLP. Both soluble and insoluble lignin fractions were significantly reduced, with an overall removal rate of 80–90%. Contrary to prior beliefs about the recalcitrance of azo dyes, B. adusta demonstrated substantial biodegradation capabilities, even on non-lignocellulosic substrates, such as dairy waste. The decolorization efficacy varied with dye structure, suggesting that efficiency should not be judged solely on color reduction. Remarkably, B. adusta also effectively decolorized and removed lignin from actual mill effluents without pH alteration, indicating a viable low-cost bioremediation strategy. This invites further investigation into optimizing B. adusta for industrial wastewater biodecolorization, especially in the field of PAHs (Polycyclic Aromatic Hydrocarbons) and EDCs (Endocrine Disrupting Chemicals). [ABSTRACT FROM AUTHOR]

Published
2024
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9. Up-Cycling of Olea europaea L. Ancient Cultivars Side Products: Study of a Combined Cosmetic–Food Supplement Treatment Based on Leaves and Olive Mill Wastewater Extracts

Author

Buzzi, Raissa, primary, Gugel, Irene, additional, Costa, Stefania, additional, Molesini, Sonia, additional, Boreale, Silvia, additional, Baldini, Erika, additional, Marchetti, Nicola, additional, Vertuani, Silvia, additional, Pinelli, Patrizia, additional, Urciuoli, Silvia, additional, Baldisserotto, Anna, additional, and Manfredini, Stefano, additional

Published
2023
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10. A Safe-by-Design Approach for the Synthesis of a Novel Cross-Linked Hyaluronic Acid with Improved Biological and Physical Properties

Author

Sciabica, Sabrina, primary, Barbari, Riccardo, additional, Fontana, Riccardo, additional, Tafuro, Giovanni, additional, Semenzato, Alessandra, additional, Traini, Daniela, additional, Silva, Dina M., additional, Reis, Larissa Gomes Dos, additional, Canilli, Luisa, additional, Terno, Massimo, additional, Marconi, Peggy, additional, Baldisserotto, Anna, additional, Vertuani, Silvia, additional, and Manfredini, Stefano, additional

Published
2023
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11. Magnolia officinalis L. bark extract and respiratory diseases: From traditional Chinese medicine to western medicine via network target

Author

Fontana, Riccardo, primary, Mattioli, Laura Beatrice, additional, Biotti, Giulia, additional, Budriesi, Roberta, additional, Gotti, Roberto, additional, Micucci, Matteo, additional, Corazza, Ivan, additional, Marconi, Peggy, additional, Frosini, Maria, additional, Manfredini, Stefano, additional, Buzzi, Raissa, additional, and Vertuani, Silvia, additional

Published
2023
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14. A Safe-by-Design Approach to “Reef Safe” Sunscreens Based on ZnO and Organic UV Filters

Author

Battistin, Mattia, primary, Pascalicchio, Paolina, additional, Tabaro, Beatrice, additional, Hasa, Dritan, additional, Bonetto, Alessandro, additional, Manfredini, Stefano, additional, Baldisserotto, Anna, additional, Scarso, Alessandro, additional, Ziosi, Paola, additional, Brunetta, Andrea, additional, Brunetta, Fabio, additional, and Vertuani, Silvia, additional

Published
2022
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17. Phylogenomic analysis of the genus Leuconostoc

Author

Raimondi, Stefano, primary, Candeliere, Francesco, additional, Amaretti, Alberto, additional, Costa, Stefania, additional, Vertuani, Silvia, additional, Spampinato, Gloria, additional, and Rossi, Maddalena, additional

Published
2022
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19. Benzothiazole Derivatives as Multifunctional Antioxidant Agents for Skin Damage: Structure–Activity Relationship of a Scaffold Bearing a Five-Membered Ring System

Author

Djuidje, Ernestine Nicaise, primary, Barbari, Riccardo, additional, Baldisserotto, Anna, additional, Durini, Elisa, additional, Sciabica, Sabrina, additional, Balzarini, Jan, additional, Liekens, Sandra, additional, Vertuani, Silvia, additional, and Manfredini, Stefano, additional

Published
2022
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20. Machine Learning Data Augmentation as a Tool to Enhance Quantitative Composition–Activity Relationships of Complex Mixtures. A New Application to Dissect the Role of Main Chemical Components in Bioactive Essential Oils

Author

Ragno, Alessio, primary, Baldisserotto, Anna, additional, Antonini, Lorenzo, additional, Sabatino, Manuela, additional, Sapienza, Filippo, additional, Baldini, Erika, additional, Buzzi, Raissa, additional, Vertuani, Silvia, additional, and Manfredini, Stefano, additional

Published
2021
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21. Design, Synthesis, Characterization, and In Vitro Evaluation of a New Cross-Linked Hyaluronic Acid for Pharmaceutical and Cosmetic Applications

Author

Sciabica, Sabrina, primary, Tafuro, Giovanni, additional, Semenzato, Alessandra, additional, Traini, Daniela, additional, Silva, Dina M., additional, Reis, Larissa Gomes Dos, additional, Canilli, Luisa, additional, Terno, Massimo, additional, Durini, Elisa, additional, Vertuani, Silvia, additional, Baldisserotto, Anna, additional, and Manfredini, Stefano, additional

Published
2021
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23. A Safe-by-Design Approach to 'Reef Safe' Sunscreens Based on ZnO and Organic UV Filters

Author

Mattia Battistin, Paolina Pascalicchio, Beatrice Tabaro, Dritan Hasa, Alessandro Bonetto, Stefano Manfredini, Anna Baldisserotto, Alessandro Scarso, Paola Ziosi, Andrea Brunetta, Fabio Brunetta, Silvia Vertuani, Battistin, Mattia, Pascalicchio, Paolina, Tabaro, Beatrice, Hasa, Dritan, Bonetto, Alessandro, Manfredini, Stefano, Baldisserotto, Anna, Scarso, Alessandro, Ziosi, Paola, Brunetta, Andrea, Brunetta, Fabio, and Vertuani, Silvia

Subjects
cosmetic, ZnO, sunscreen, photocatalysis, superoxide anion, hydroxy radical, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Triazone, Physiology, Clinical Biochemistry, Cell Biology, Settore CHIM/06 - Chimica Organica, Biochemistry, photocatalysi, Molecular Biology
Abstract

In recent years, the issue of coral bleaching has led to restrictions in some tropical locations (i.e., Palau, Hawaii, etc.) on the use of some organic UV sunscreen filters, such as oxybenzone and ethyl hexyl methoxycinnamate. In contrast, ZnO is considered safe for marine environments and thus is often used without considering its photocatalytic and oxidative activities related to the generation of O2•− and HO•. Moreover, ZnO needs to be used in combination with other filters to reach higher protection factors. Thus, the study of its interaction with formulations and with organic filters is important in sunscreen technology for the development of safer by-design products. In this work, the photocatalytic activity of zinc oxides with different surface areas (30, 25 and 9 m2/g) and their interaction with selected organic sunscreen filters were investigated. In particular, the ZnO photocatalytic kinetics were studied following the photodegradation of Acid Blue 9 (AB9) observing a first-order reaction with a chemical regime. Our evaluations of the selective inhibitions by hvb+ and HO• demonstrated a substantial predominance of the hydroxide radicals in the expression of the photocatalysis, a trend that was also confirmed by the irradiation of ZnO in an ethanolic solution. Indeed, the formulations containing both ZnO and organic filters defined as “safe” for coral reefs (i.e., Diethylamino Hydroxybenzoyl Hexyl Benzoate, DHHB, and Ethylhexyl Triazone, EHT) showed a non-negligible photocatalytic oxidation and thus the combination was underlined as safe to use.

Published
2022

24. Guidelines for the Development of Herbal-Based Sunscreen

Author

Manfredini, Stefano, Buso, Piergiacomo, Radice, Matteo, Vertuani, Silvia, and Baldisserotto, Anna

Subjects
Medical / Alternative & Complementary Medicine
Abstract

Sun protection is a complex topic, which involves various classes of compounds. The photoprotective effectiveness of a sunscreen involves many biological activities, such as ultraviolet (UV) radiation filter properties and antioxidant, anti-inflammatory, and antimutagenic effects. Formulation strategy is also a key factor. Several studies have examined the role of natural molecules as photoprotective compounds, and a considerable number of commercially available sunscreens contain herbal extracts but not as sunfilters. Indeed, the process of evaluation of UV-filtering and photoprotective activity of herbal compounds presents certain specific difficulties and needs in vitro and in vivo studies. Nowadays, no natural compound or vegetal extract has been approved by any country as official UV filter for sunscreen. With these premises, the aim of this chapter is to define a set of tests, which can help to evaluate the efficacy of an herbal extract in the field of sun protection; in other words, we propose a rational approach to the discovery of natural UV-filtering extract and molecules. The following electronic databases have been used as a source of information: SciFinder, PubMed, Google Scholar, ISI-Web of Science, and Scopus.

Published
2022

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