1. Bicuspid Aortic Valve Disease with Early-Onset Complications: Characteristics and Aortic Outcomes.
- Author
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Selbst, Maximilian A., Ward, Colin R., Svetgoff, Megan L., Michelena, Hector I., Sabate-Rotes, Anna, De Backer, Julie, Mosquera, Laura Muiño, Yetman, Anji T., Bissell, Malenka M., Andreassi, Maria Grazia, Foffa, Ilenia, Hui, Dawn S., Caffarelli, Anthony, Kim, Yuli Y., Guo, Dongchuan, Citro, Rodolfo, De Marco, Margot, Tretter, Justin T., Morris, Shaine A., and McBride, Kim L.
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CONGENITAL heart disease , *YOUNG adults , *THORACIC aneurysms , *MITRAL valve , *AORTIC valve diseases - Abstract
Bicuspid aortic valve (BAV) is the most common congenital heart malformation in adults, but it can also cause childhood-onset complications. The presentation and clinical course of young adults who present due to BAV complications are relatively uncharacterized. In a multicenter study, we found that young people who experience significant complications related to BAV disease before age 30 are distinguished from the majority of BAV cases that manifest after age 50 by a relatively severe clinical course, with higher rates of surgical interventions, more frequent second interventions, and a greater burden of congenital heart malformations. These observations highlight the need for prompt recognition, regular lifelong surveillance, and targeted interventions to address the significant health burdens of patients with early-onset BAV complications. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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