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9. Additional file 1 of Integrated models of blood protein and metabolite enhance the diagnostic accuracy for Non-Small Cell Lung Cancer

Author

Xu, Runhao, Wang, Jiongran, Zhu, Qingqing, Zou, Chen, Wei, Zehao, Wang, Hao, Ding, Zian, Meng, Minjie, Wei, Huimin, Xia, Shijin, Wei, Dongqing, Deng, Li, and Zhang, Shulin

Abstract

Additional file 1: Supplementary Figure 1. GO Enrichment pathway associated with cellular component, and biological process. Supplementary Figure 2. The differentially expression of 10 plasma protein candidates among three groups. Supplementary Figure 3. The differentially expression of 14 serum amino acids among three groups. Supplementary Figure 4. The differentially expression of 15 bile acids among three groups. Supplementary Figure 5. The differentially expression of six classic tumor markers among three groups. Supplementary Figure 6. Proteins and amnio acids related to NSCLC stage. Supplementary Figure 7. Single index with AUC>0.7 for NSCLC screening. Supplementary Figure 8. Single index with AUC>0.7 in differentiating NSCLC and BPD. Supplementary Figure 9.The process and the result of binary logistic regression with backward elimination methods. Supplementary Table 1. Screened differentially expressed proteins and corresponding validation proteins. Supplementary Table 2. Performance of single predictor in NSCLC screening. Supplementary Table 3. Performance of single predictor in NSCLC diagnosis. Supplementary Table 4. Screening model by stepwise binary logistic regression analysis in training samples. Supplementary Table 5. Performance analysis of 3 models in screening NSCLC. Supplementary Table 6. Testing of 3 models in screening NSCLC. Supplementary Table 7. Diagnosis model by stepwise binary logistic regression analysis in training samples. Supplementary Table 8. Performance analysis of 3 models in differentiating NSCLC and BPD. Supplementary Table 9. Testing of 3 models in differentiating NSCLC and BPD. Supplementary Table 10. The concentration units of these candidates.

Published
2023
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