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Abstract Background Coupled with its rising prevalence, Autism spectrum disorder (ASD) has become a globally recognized public health concern. Nevertheless, large-scale, multicenter studies that analyze the epidemiology of ASD in China are relatively scarce. Methods Literature searches were conducted in PubMed/Medline, Embase, the Cochrane Library, Wanfang Data Knowledge Service Platform, China Biology Medicine database (CBM), China Science and Technology Journal Database (CSTJ), and China National Knowledge Infrastructure (CNKI) to retrieve studies published before April 8, 2023, related to ASD prevalence among children aged 0 to 14 years in mainland China. Meta-analysis was conducted using RevMan 5.2 and Stata 14.0. Results Twenty-one articles were included. The ASD prevalence among children in mainland China has been 0.7% (95% confidence interval(CI): 0.006–0.008) since 2017. The prevalence of ASD among boys was 1.0% (95% CI: 0.008–0.011), which was significantly higher than that among girls at 0.2% (95% CI: 0.002–0.003), with a statistically significant difference (OR = 3.198, 95% CI: 2.489–4.109, P = 0.000). Among the included studies, 18 reported an ASD prevalence of 0.8% (95% CI: 0.007–0.010), while 3 studies reported an autistic disorder (AD) prevalence of 0.7% (95% CI: 0.006–0.008). The prevalence of autism among urban children was 23.9% (95% CI: 0.149–0.328), and in rural areas, it was 0.7% (95% CI: 0.002–0.013), with no statistically significant difference (OR = 1.342, 95% CI: 0.258–6.975, P = 0.727). Regression analysis showed that factors such as region (P = 0.000), age (P = 0.000), study period (P = 0.000), sample size (P = 0.000), sampling method (P = 0.002), population source (P = 0.000), disease type (P = 0.000), quality score of the study (P = 0.000), and diagnostic criteria (P = 0.000) might have contributed to the heterogeneity in ASD prevalence. Conclusion The prevalence of ASD in China from 2017 to 2023 was 7/1000, showing an upward trend compared to that before 2017 (26.50/10,000). The male-to-female prevalence ratio was 5:1.The overall prevalence remained significantly lower than that reported in foreign countries.

Optical sensors using fiber Bragg gratings (FBGs) have become an alternative to traditional electronic sensors thanks to their immunity against electromagnetic interference, their applicability in harsh environments, and other advantages. However, the complexity and high cost of the FBG interrogation systems pose a challenge for the wide deployment of such sensors. Herein, we present a clean and cost-effective method for interrogating an FBG temperature sensor using a micro-chip called the waveguide spectral lens (WSL) and a standard CMOS camera. This interrogation system can project the FBG transmission spectrum onto the camera without any free-space optical components. Based on this system, an FBG temperature sensor is developed, and the results show good agreement with a commercial optical spectrum analyzer (OSA), with the respective wavelength-temperature sensitivity measured as 6.33 pm/°C for the WSL camera system and 6.32 pm/°C for the commercial OSA. Direct data processing on the WSL camera system translates this sensitivity to 0.44 μm/°C in relation to the absolute spatial shift of the FBG spectra on the camera. Furthermore, a deep neural network is developed to train the spectral dataset, achieving a temperature resolution of 0.1 °C from 60 °C to 120 °C, while direct processing on the valley/dark line detection yields a resolution of 7.84 °C. The proposed hardware and the data processing method may lead to the development of a compact, practical, and low-cost FBG interrogator.

A function-versatile thermo-optic switch is proposed and experimentally demonstrated using silicon nitride waveguides embedded in polymer cladding. The device consists of a 1 × 2 input splitter, 2 single-mode waveguides for phase shifting, and a thermally controlled 2 × 2 output coupler to give another degree of freedom in achieving phase-matching conditions. Combining the high waveguide birefringence of the thin silicon nitride waveguide and the excellent thermo-optic property of the polymer material, this device can realize multiple functions by applying different micro-heater powers, i.e., polarization-independent path switching, beam splitting, and polarization beam splitting. For the polarization-independent path switching, the fabricated device has shown a crosstalk suppression better than 10 dB for the TE mode and over 20 dB for the TM mode in the wavelength range from 1500 nm to 1620 nm. For the polarization beam splitting function, the device can reach a polarization extinction ratio greater than 10 dB at selected bands. This simple yet scalable device may find applications in polarization-multiplexed optical communication technology and complex photonic computing networks.

We present the design of a planar spectrometer that separates the wavelength channels from an input fiber and focuses the spectral lines onto a camera without any free-space optical elements. The geometric arrangements of the waveguides to achieve different spectroscopic parameters are explained in detail, allowing adjustable focal lengths, high spectral resolution, and broad free spectral range. The optical chip is fabricated on a low-cost polymer platform as proof of concept. The optical spectrum of a multiwavelength laser is measured by the proposed device, and the result is in good agreement with a commercial optical spectrum analyzer. The large focal depth of the chip allows an optical assembly of much relaxed alignment accuracy. We demonstrate a tube design to encapsulate the chip fixed with the input fiber. The assembly is then mounted to a commercial camera with standard C-mount threading as a convenient fiber spectrum analyzer without customized detectors and circuits. Our design may provide a low-cost and versatile solution for the development of compact spectroscopic equipment.