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Your search keyword '"Yi, Kui"' showing total 136 results
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136 results on '"Yi, Kui"'

17. Self-adaptive seismic data reconstruction and denoising using dictionary learning based on morphological component analysis

Author

De-Ying Wang, Xing-Rong Xu, Hua-Hui Zeng, Jia-Qing Sun, Xin Xu, and Yi-Kui Zhang

Subjects
compressed sensing, dictionary learning, morphological component analysis, seismic data reconstruction, seismic data denoising, Science
Abstract

Data reconstruction and data denoising are two critical preliminary steps in seismic data processing. Compressed Sensing states that a signal can be recovered by a series of solving algorithms if it is sparse in a transform domain, and has been well applied in the field of reconstruction, when, sparse representation of seismic data is the key point. Considering the complexity and diversity of seismic data, a single mathematical transformation will lead to incomplete sparse expression and bad restoration effects. Morphological Component Analysis (MCA) decomposes a signal into several components with outstanding morphological features to approximate the complex internal data structure. However, the representation ability of combined dictionaries is constrained by the number of dictionaries, and cannot be self-adaptively matched with the data features. Dictionary learning overcomes the limitation of fixed base function by training dictionaries that are fully suitable for processed data, but requires huge amount of time and considerable hardware cost. To solve the above problems, a new dictionary library (K-Singluar Value Decomposition learning dictionary and Discrete Cosine Transform dictionary) is hereby proposed based on the efficiency of fixed base dictionary and the high precision of learning dictionary. The self-adaptive sparse representation is achieved under the Morphological Component Analysis framework and is successfully applied to the reconstruction and denoising of seismic data. Real data tests have proved that the proposed method performs better than single mathematical transformation and other combined dictionaries.

Published
2023
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22. An update on the use of antihistamines in managing chronic urticaria.

Author

Xiang, Yi-Kui, Fok, Jie Shen, Podder, Indrashis, Yücel, Muhammed Burak, Özkoca, Defne, Thomsen, Simon Francis, and Kocatürk, Emek

Subjects
ANTIHISTAMINES, URTICARIA, SKIN diseases, GENOMICS, MOLECULAR genetics
Abstract

Urticaria, a mast cell-mediated skin disease, manifests as acute or chronic, with the latter divided into spontaneous and inducible types and requires individualized management, including identifying triggers and comorbidities. Antihistamines, particularly the second generation group, form the mainstay of primary treatment plans consisting of dosage adjustments and/or in combination with other treatment modalities depending on underlying disease control. A literature search was conducted using 'antihistamines,' 'urticaria,' 'pharmacogenomics,' 'genomics,' 'biomarkers' and 'treatment response' as key words. In this review, we focus on the comprehensive understanding and application of antihistamines in managing adult and adolescent patients with chronic urticaria. Using antihistamines to treat urticaria is set to change significantly, focusing more on personalized medicine and identifying key biomarkers to enhance treatment response prediction. These changes aim to make treatments more specific and cost-effective by avoiding unnecessary tests. Applying new approaches in everyday clinical care faces challenges like proving the biomarkers' reliability, updating current guidelines, and incorporating individualized treatments into standard procedures. Efforts should now concentrate on finding easy-to-use biomarkers, improving access to pharmacogenomics, understanding why some patients are resistant to treatment, and creating more specific treatment options based on patient needs. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Effects of oral immunonutritional supplement on 3-year disease-free survival in gastric cancer patients with pathological stage III after total gastrectomy (CRUCIAL): study protocol of a multicentre, randomised clinical trial

Author

Zhou, Da, primary, Liu, Yuxiu, additional, Zhang, Li, additional, Lu, Mengjie, additional, Gao, Xuejin, additional, Li, Guoli, additional, Xiang, Xiaosong, additional, Xu, Hao, additional, Li, Gang, additional, Sun, Zhiping, additional, Wei, Wei, additional, Yi, Kui, additional, Zuo, Junbo, additional, Wu, Yugang, additional, Qian, Jun, additional, Zhou, Jian, additional, Duan, Kaipeng, additional, Wu, Yong, additional, Tian, Zhiqiang, additional, Jiang, Chao, additional, and Wang, Xinying, additional

Published
2023
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32. Autoreactive IgE: pathogenic role and therapeutic target in autoimmune diseases

Author

Nicolas CHARLES, Inge Kortekaas Krohn, Emek Kocatürk, Jörg Scheffel, Sabine Altrichter, Carolin Steinert, Yi-Kui Xiang, Jan Gutermuth, Laurent Reber, Marcus Maurer, Gerontology, Dermatology, and Brussels Interdisciplinary Research centre on Migration and Minorities

Abstract

Autoimmunity is the break of tolerance to self-antigens that leads to organ-specific or systemic diseases characterized by the presence of pathogenic autoreactive antibodies (AAb) produced by plasmablast and/or plasma cells. AAb are prevalent in the general population and not systematically associated with clinical symptoms. In contrast, in some individuals, these AAb are pathogenic and drive the development of signs and symptoms of antibody-mediated autoimmune diseases (AbAID). AAb production, isotype profiles, and glycosylations are promoted by pro-inflammatory triggers linked to genetic, environmental, and hormonal parameters. Recent evidence supports a role for pathogenic AAb of the IgE isotype in a number of AbAID. Autoreactive IgE can drive the activation of mast cells, basophils and other types of FcεRI-bearing cells and may play a role in promoting autoantibody production and other pro-inflammatory pathways. In this review, we discuss the current knowledge on the pathogenicity of autoreactive IgE in AbAID and their status as therapeutic targets. We also highlight unresolved issues including the need for assays that reproducibly quantify IgE AAbs, to validate their diagnostic and prognostic value, and to further study their pathophysiological contributions to AbAID.

Published
2023

36. 激光薄膜元件内微缺陷的表征分析

Author

Cui Yun, 崔云, primary, Zhang Ge, 张革, additional, Zhao Yuanan, 赵元安, additional, Shao Yuchuan, 邵宇川, additional, Zhu Meiping, 朱美萍, additional, Yi Kui, 易葵, additional, and Shao Jianda, 邵建达, additional

Published
2023
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41. Autoimmune chronic spontaneous urticaria

Author

Kolkhir, Pavel, primary, Muñoz, Melba, additional, Asero, Riccardo, additional, Ferrer, Marta, additional, Kocatürk, Emek, additional, Metz, Martin, additional, Xiang, Yi-Kui, additional, and Maurer, Marcus, additional

Published
2022
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45. 激光薄膜元件内微缺陷的表征分析

Author

崔云 Cui Yun, 张革 Zhang Ge, 赵元安 Zhao Yuanan, 邵宇川 Shao Yuchuan, 朱美萍 Zhu Meiping, 易葵 Yi Kui, and 邵建达 Shao Jianda

Subjects
Electrical and Electronic Engineering, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published
2023

46. 金刚石减反射微纳结构制备技术研究进展

Author

张伟丽 Zhang Weili, 史肖阳 Shi Xiaoyang, 洪瑞金 Hong Ruijin, 陈兴凤 Chen Xingfeng, 冯操 Feng Cao, and 易葵 Yi Kui

Subjects
Electrical and Electronic Engineering, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published
2023

47. Autoimmune chronic spontaneous urticaria

Author

Pavel Kolkhir, Melba Muñoz, Riccardo Asero, Marta Ferrer, Emek Kocatürk, Martin Metz, Yi-Kui Xiang, Marcus Maurer, and Publica

Subjects
Urticaria, treatment, Immunology, autoimmunity, IgG-anti-TPO, BAT, markers, type I, Immunoglobulin E, Chronic spontaneous urticaria, type IIb, BHRA, autoallergy, Immunoglobulin G, Chronic Disease, Humans, Immunology and Allergy, Chronic Urticaria, IgE, Autoantibodies
Abstract

Chronic spontaneous urticaria (CSU) is a debilitating mast cell-driven disease characterized by recurrent wheals and/or angioedema. Substantial progress has been made in dissecting the 2 main autoimmune mechanisms that drive the pathogenesis of CSU. Type I autoimmune (autoallergic) CSU is associated with IgE antibodies against autoantigens, for example, thyroid peroxidase and IL-24. Type IIb autoimmune CSU is mediated by autoantibodies that activate mast cells, for example, via IgE and FcεRI, and is present in less than 10% of patients with CSU when strict criteria are used, that is, triple positivity of autologous serum skin test, immunoassays for IgG autoantibodies, and basophil activation tests. A subpopulation of patients with CSU has both types. Type IIb autoimmune CSU is characterized by higher disease severity, concomitant autoimmune diseases, low levels of total IgE, elevated levels of IgG-anti-thyroid peroxidase, basopenia, eosinopenia, poor response to antihistamines and to omalizumab, and a good response to cyclosporine. Novel targeted therapies for CSU are under development such as ligelizumab, an anti-IgE, fenebrutinib and remibrutinib, Bruton's tyrosine kinase inhibitors, and dupilumab, an anti-IL-4Rα. Further studies should investigate the overlap between autoallergic and type IIb autoimmune CSU, optimize the diagnosis of both autoimmune endotypes using easy-to-perform, noninvasive, and inexpensive markers, and assess differences in response to therapy.

Published
2022

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