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Your search keyword '"Yong, Tingting"' showing total 4 results
Start Over Author "Yong, Tingting" Publication Year Range Last 3 years
4 results on '"Yong, Tingting"'

1. Employing a PhI(OAc)2-mediated domino reaction to assemble nitrogen-containing heterocyclic derivatives and assessing their anti-inflammatory activity.

Author

Li, Xinyue, Fang, Yuhua, Zhao, Yuanyuan, Luo, Shenshen, Xue, Yuhui, Yong, Tingting, and Wang, Bin

Subjects
COLUMN chromatography, PYRAZOLE derivatives, ANTI-inflammatory agents, FUNCTIONAL groups, OXYGEN
Abstract

Metal-free radical cascade synthesis of substituted pyrazole derivatives was initiated by PhI(OAc)2 at 23 °C. This protocol features wide functional group tolerance, a simple purification process without column chromatography, and an oxygen migration. Compound 5 demonstrated significant anti-inflammatory activity, indicating potential for therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Employing a PhI(OAc) 2 -mediated domino reaction to assemble nitrogen-containing heterocyclic derivatives and assessing their anti-inflammatory activity.

Author

Li X, Fang Y, Zhao Y, Luo S, Xue Y, Yong T, and Wang B

Subjects
Animals, Mice, Molecular Structure, Anti-Inflammatory Agents, Non-Steroidal chemistry, Anti-Inflammatory Agents, Non-Steroidal pharmacology, Anti-Inflammatory Agents, Non-Steroidal chemical synthesis, Pyrazoles chemistry, Pyrazoles pharmacology, Pyrazoles chemical synthesis, Anti-Inflammatory Agents chemistry, Anti-Inflammatory Agents pharmacology, Anti-Inflammatory Agents chemical synthesis, Structure-Activity Relationship, Heterocyclic Compounds chemistry, Heterocyclic Compounds pharmacology, Heterocyclic Compounds chemical synthesis, Nitrogen chemistry
Abstract

Metal-free radical cascade synthesis of substituted pyrazole derivatives was initiated by PhI(OAc) 2 at 23 °C. This protocol features wide functional group tolerance, a simple purification process without column chromatography, and an oxygen migration. Compound 5 demonstrated significant anti-inflammatory activity, indicating potential for therapy.

Published
2024
Full Text
View/download PDF

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