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Following The Royal Society's decision to allow the release of hitherto confidential documents concerning referees' reports and other material relating to the publication of historical manuscripts, the present paper examines the exchanges preceding the publication of the two papers on turbulent flow by Osborne Reynolds that have so greatly influenced the development of Engineering Fluid Mechanics over the past century. The documents cited reveal that, although the earlier experimental paper was warmly welcomed, the referees were critical of the subsequent analytical contribution, it appears that the publication of the latter paper was due mainly to the considerable standing Reynolds had by then acquired, in part from the impact of his experimental paper published 12 years earlier. The paper also provides a summary of Reynolds' career and research prior to his embarking on the research published in the two seminal papers. [ABSTRACT FROM AUTHOR]

Rotating-disk flows were first considered by von Kármán in a seminal paper in 1921, where boundary layers in general were discussed and, in two of the nine sections, results for the laminar and turbulent boundary layers over a rotating disk were presented. It was not until in 1955 that flow visualization discovered the existence of stationary cross-flow vortices on the disk prior to the transition to turbulence. The rotating disk can be seen as a special case of rotating cones, and recent research has shown that broad cones behave similarly to disks, whereas sharp cones are susceptible to a different type of instability. Here, we provide a review of the major developments since von Kármán's work from 100 years ago, regarding instability, transition, and turbulence in the boundary layers, and we include some analysis not previously published. [ABSTRACT FROM AUTHOR]

Global agreement on 30×30 means an unprecedented last push to define how much nature will be left on the planet. At the same time that space for nature is being defined, climate change will be moving nature around. Species are now on the move to track climate change both on land and in the oceans, a process that is accelerating under dramatic new extreme events. This is an opportune time to review conservation recommendations made early in the millennium, to see how many have been taken on board over the past 20 years, and how much is left to be done to adapt to climate change as conservation pushes toward 30×30. The history of Climate Change–Integrated Conservation Strategies begins with two papers published by a group of prominent climate change biologists in 2002. The importance of including adaptation to climate change in conservation was underscored by the first estimates of extinction risk due to climate change in 2004. Subsequent literature has developed concepts such as velocity of climate change and assisted migration. Regional modeling of biodiversity change, expanding protected areas to facilitate species range movements, and managing productive landscapes to facilitate species movements are all now considered "business as usual" for conservation planning for climate change. Regional coordination of conservation efforts to ensure that species on the move are managed for climate change consistently across their range, on the other hand, is under-represented in literature and practice. Improving both theory and practice of regional coordination for climate change is an important priority for conservation now and in the future. Conservation for climate change has focused mostly on warming scenarios, but failure to act on climate change emissions reduction means that meeting Paris Agreement targets will almost certainly have to include both warming past those targets and subsequent cooling back to the target. Managing this double transition is a second critical point of emphasis for climate change biology as the world moves to 30×30. [ABSTRACT FROM AUTHOR]

Several peer-reviewed papers and reviews have examined the relationship between exposure to air pollution and COVID-19 spread and severity. However, many of the existing reviews on this topic do not extensively present the statistical challenges associated with this field, do not provide comprehensive guidelines for future researchers, and review only the results of a relatively small number of papers. We reviewed 139 papers, 127 of which reported a statistically significant positive association between air pollution and adverse COVID-19 health outcomes. Here, we summarize the evidence, describe the statistical challenges, and make recommendations for future research. To summarize the 139 papers with data from geographical locations around the world, we also present anopen-source data visualization tool that summarizes these studies and allows the research community to contribute evidence as new research papers are published. [ABSTRACT FROM AUTHOR]

The interactions of textiles with moisture have been thoroughly studied in textile research, while fluid mechanists and soft matter physicists have partially investigated the underlying physics phenomena. A description of liquid morphologies in fibrous assemblies allows one to characterize the associated capillary forces and their impact on textiles, and to organize their complex moisture transport dynamics. This review gathers some of the common features and fundamental mechanisms at play in textile–liquid interactions, with selected examples ranging from knitted fabrics to nonwoven paper sheets, associated with experiments on model systems. [ABSTRACT FROM AUTHOR]

Patient-reported outcomes are recognized as essential for the evaluation of medical and public health interventions. Over the last 50 years, health-related quality of life (HRQoL) research has grown exponentially from 0 to more than 17,000 papers published annually. We provide an overview of generic HRQoL measures used widely in epidemiological studies, health services research, population studies, and randomized clinical trials [e.g., Medical Outcomes Study SF-36 and the Patient-Reported Outcomes Measurement Information System (PROMIS®)-29]. In addition, we review methods used for economic analysis and calculation of the quality-adjusted life year (QALY). These include the EQ-5D, the Health Utilities Index (HUI), the self-administered Quality of Well-being Scale (QWB-SA), and the Health and Activities Limitation Index (HALex). Furthermore, we consider hybrid measures such as the SF-6D and the PROMIS-Preference (PROPr). The plethora of HRQoL measures has impeded cumulative science because incomparable measures have been used in different studies. Linking among different measures and consensus on standard HRQoL measurement should now be prioritized. In addition, enabling widespread access to common measures is necessary to accelerate future progress. [ABSTRACT FROM AUTHOR]

Urban climate policy offers a significant opportunity to promote improved public health. The evidence around climate and health cobenefits is growing but has yet to translate into widespread integrated policies. This article presents two systematic reviews: first, looking at quantified cobenefits of urban climate policies, where transportation, land use, and buildings emerge as the most studied sectors; and second, looking at review papers exploring the barriers and enablers for integrating these health cobenefits into urban policies. The latter reveals wide agreement concerning the need to improve the evidence base for cobenefits and consensus about the need for greater political will and leadership on this issue. Systems thinking may offer a way forward to help embrace complexity and integrate health cobenefits into decision making. Knowledge coproduction to bring stakeholders together and advance policy-relevant research for urban health will also be required. Action is needed to bring these two important policy agendas together. [ABSTRACT FROM AUTHOR]

The civil rights and women's movements led to momentous changes in public policy and corporate practice that have made the United States the global paragon of equal opportunity. Yet diversity in the corporate hierarchy has increased incrementally. Lacking clear guidance from policymakers, personnel experts had devised their own arsenal of diversity programs. Firms implicated their own biased managers through diversity training and grievance systems and created a paper trail for personnel decisions, but they maintained the deeper structures that perpetuate inequality. Firms that changed systems for recruiting and developing workers, organizing work, and balancing work and life saw diversity increase up the hierarchy, but those firms are all too rare. The courts and federal agencies have found management processes that do not explicitly discriminate to be plausibly unbiased, and they rarely require systemic reforms. Our elaborate corporate diversity programs and public regulatory systems have largely failed to open opportunity, but social science research points to a path forward. [ABSTRACT FROM AUTHOR]

Two groundbreaking papers published in 1954 laid out the theory of the mechanism of muscle contraction based on force-generating interactions between myofilaments in the sarcomere that cause filaments to slide past one another during muscle contraction. The succeeding decades of research in muscle physiology have revealed a unifying interest: to understand the multiscale processes—from atom to organ—that govern muscle function. Such an understanding would have profound consequences for a vast array of applications, from developing new biomimetic technologies to treating heart disease. However, connecting structural and functional properties that are relevant at one spatiotemporal scale to those that are relevant at other scales remains a great challenge. Through a lens of multiscale dynamics, we review in this article current and historical research in muscle physiology sparked by the sliding filament theory. [ABSTRACT FROM AUTHOR]

Intrinsically disordered proteins (IDPs) are now widely recognized as playing critical roles in a broad range of cellular functions as well as being implicated in diverse diseases. Their lack of stable secondary structure and tertiary interactions, coupled with their sensitivity to measurement conditions, stymies many traditional structural biology approaches. Single-molecule Forster resonance energy transfer (smFRET) is now widely used to characterize the physicochemical properties of these proteins in isolation and is being increasingly applied to more complex assemblies and experimental environments. This review provides an overview of confocal diffusion-based smFRET as an experimental tool, including descriptions of instrumentation, data analysis, and protein labeling. Recent papers are discussed that illustrate the unique capability of smFRET to provide insight into aggregation-prone IDPs, protein-protein interactions involving IDPs, and IDPs in complex experimental milieus. [ABSTRACT FROM AUTHOR]

Creating more physical activity-supportive built environments is recommended by the World Health Organization for controlling noncommunicable diseases. The IPEN (International Physical Activity and Environment Network) Adult Study was undertaken to provide international evidence on associations of built environments with physical activity and weight status in 12 countries on 5 continents (n > 14,000). This article presents reanalyzed data from eight primary papers to identify patterns of findings across studies. Neighborhood environment attributes, whether measured objectively or by self-report, were strongly related to all physical activity outcomes (accelerometer-assessed total physical activity, reported walking for transport and leisure) and meaningfully related to overweight/obesity. Multivariable indexes of built environment variables were more strongly related to most outcomes than were single-environment variables. Designing activity-supportive built environments should be a higher international health priority. Results provide evidence in support of global initiatives to increase physical activity and control noncommunicable diseases while achieving sustainable development goals. [ABSTRACT FROM AUTHOR]

Intrinsically disordered proteins (IDPs) are now widely recognized as playing critical roles in a broad range of cellular functions as well as being implicated in diverse diseases. Their lack of stable secondary structure and tertiary interactions, coupled with their sensitivity to measurement conditions, stymies many traditional structural biology approaches. Single-molecule Förster resonance energy transfer (smFRET) is now widely used to characterize the physicochemical properties of these proteins in isolation and is being increasingly applied to more complex assemblies and experimental environments. This review provides an overview of confocal diffusion-based smFRET as an experimental tool, including descriptions of instrumentation, data analysis, and protein labeling. Recent papers are discussed that illustrate the unique capability of smFRET to provide insight into aggregation-prone IDPs, protein–protein interactions involving IDPs, and IDPs in complex experimental milieus. [ABSTRACT FROM AUTHOR]

Soft porous solids can change their shapes by absorbing liquids via capillarity. Such poro-elasto-capillary interactions can be seen in the wrinkling of paper, swelling of cellulose sponges, and morphing of resurrection plants. Here, we introduce physical principles relevant to the phenomena and survey recent advances in the understanding of swelling and shrinkage of bulk soft porous media due to wetting and drying. We then consider various morphing modes of porous sheets, which are induced by localized wetting and swelling of soft porous materials. We focus on physical insights with the aim of triggering novel experimental findings and promoting practical applications. [ABSTRACT FROM AUTHOR]

Dear readers: We are sad to report that, soon after submitting her draft manuscript for this prefatory chapter, Nancy Grace Roman passed away on December 25, 2018. This final version of her memoir has been lightly edited but remains very true to the original. However, an Abstract was missing. Rather than trying to synthesize one in Nancy Grace's inimitable style, we take this opportunity to comment briefly on her life and its significance. Nancy Grace Roman was born in 1925 and came of age scientifically in the United States during the 1940s and 1950s. Together with the equally fascinating prefatory by Vera Rubin (ARAA, Vol. 49), which we also recommend to you, these two memoirs give us intimate insight into the obstacles faced by women astronomers trying to rise in the field during those years. Roman's memoir is bitingly candid, recounting numerous snubs by teachers, insultingly small salaries, and attempts by her thesis advisor to simultaneously exploit her scientific findings and smother her role in them. Discouragement at every turn from doing forefront research is what drove Roman into government service, where she found a niche and blossomed as one of the visionary founders of the US civilian space program. We do not know what impact Roman might have had as a researcher with access to the world's largest telescopes, but we do know that her influence as an enabler of other people's science was vast. Her sobriquet as the "Mother of Hubble," bestowed by admirer Ed Weiler, is well deserved. Nancy Grace granted an audio interview to Joss Bland-Hawthorn on August 4, 2018, just a few months before her passing. It captures her persona more vividly than mere words on paper, and we recommend the online recording to you at https://www.annualreviews.org/r/nancy-grace-roman-interview. [ABSTRACT FROM AUTHOR]

2017 marks the 60th anniversary of Krebs’ seminal paper on the glyoxylate shunt (and coincidentally, also the 80th anniversary of his discovery of the citric acid cycle). Sixty years on, we have witnessed substantial developments in our understanding of how flux is partitioned between the glyoxylate shunt and the oxidative decarboxylation steps of the citric acid cycle. The last decade has shown us that the beautifully elegant textbook mechanism that regulates carbon flux through the shunt in E. coli is an oversimplification of the situation in many other bacteria. The aim of this review is to assess how this new knowledge is impacting our understanding of flux control at the TCA cycle/glyoxylate shunt branch point in a wider range of genera, and to summarize recent findings implicating a role for the glyoxylate shunt in cellular functions other than metabolism. [ABSTRACT FROM AUTHOR]

Every facet of human culture is in some way affected by our abundant, diverse insect neighbors. Our relationship with insects has been on display throughout the history of art, sometimes explicitly but frequently in inconspicuous ways. This is because artists can depict insects overtly, but they can also allude to insects conceptually or use insect products in a purely utilitarian manner. Insects themselves can serve as art media, and artists have explored or exploited insects for their products (silk, wax, honey, propolis, carmine, shellac, nest material), body parts (e.g., wings), and whole bodies (dead, alive, individually, or as collectives). This review surveys insects and their products used as media in the visual arts and considers the untapped potential for artistic exploration of media derived from insects. The history, value, and ethics of insect media art are relevant topics at a time when the natural world is at unprecedented risk. [ABSTRACT FROM AUTHOR]

The discovery of an odd virus from hematophagous arthropods 40 years ago by Stollar and Thomas described cell fusing agent virus in cells derived from Aedes aegypti mosquitoes. Then came the report of Kamiti River virus from Ae. macintoshi in 1999, followed by worldwide reports of the discovery of other viruses of mosquitoes, ticks, and midges that replicate only in arthropods and not in vertebrates or in vertebrate cells. These viruses (now totaling at least 64 published) have genomes analogous to viruses in various families that include arboviruses and nonarboviruses. It is likely that some of these viruses have been insufficiently studied and may yet be shown to infect vertebrates. However, there is no doubt that the vast majority are restricted to arthropods alone and that they represent a recently recognized clade. Their biology, modes of transmission, worldwide distribution (some have been detected in wild-caught mosquitoes in both Asia and the United States, for example), molecular characteristics of their genomes, and potential for becoming vertebrate pathogens, or at least serving as virus reservoirs, are fascinating and may provide evidence useful in understanding virus evolution. Because metagenomics studies of arthropods have shown that arthropod genomes are the sources of arthropod virus genomes, further studies may also provide insights into the evolution of arthropods. More recently, others have published excellent papers that briefly review discoveries of arthropod viruses and that characterize certain genomic peculiarities, but, to now, there have been no reviews that encompass all these facets. We therefore anticipate that this review is published at a time and in a manner that is helpful for both virologists and entomologists to make more sense and understanding of this recently recognized and obviously important virus group. This review focuses specifically on arthropod viruses in hematophagous arthropods. [ABSTRACT FROM AUTHOR]

Markov chain Monte Carlo-based Bayesian data analysis has now become the method of choice for analyzing and interpreting data in almost all disciplines of science. In astronomy, over the past decade, we have also seen a steady increase in the number of papers that employ Monte Carlo-based Bayesian analysis. New, efficient Monte Carlo-based methods are continuously being developed and explored. In this review, we first explain the basics of Bayesian theory and discuss how to set up data analysis problems within this framework. Next, we provide an overview of various Monte Carlo-based methods for performing Bayesian data analysis. Finally, we discuss advanced ideas that enable us to tackle complex problems and thus hold great promise for the future. We also distribute downloadable computer software () that implements some of the algorithms and examples discussed here. [ABSTRACT FROM AUTHOR]

Ambient ionization techniques allow complex chemical samples to be ana-lyzed in their native state with minimal sample preparation. This brings the obvious advantages of simplicity, speed, and versatility to mass spectrometry: Desorption electrospray ionization (DESI), for example, is used in chemical imaging for tumor margin diagnosis. This review on the extractive methods of ambient ionization focuses on chemical aspects, mechanistic considera-tions, and the accelerated chemical reactions occurring in charged liquid droplets generated in the spray process. DESI uses high-velocity solvent droplets to extract analytes from surfaces. Nano-DESI employs liquid ini-crojunctions for analyte dissolution, whereas paper-spray ionization uses DC potentials applied to wet porous material such as paper or biological tissue to field emit charged analyte-containing solvent droplets. These methods also operate in a reactive mode in which added reagents allow derivatization dur-ing ionization. The accelerated reaction rates seen in charged inicrodroplets are useful in small-scale rapid chemical synthesis. [ABSTRACT FROM AUTHOR]

Organic agriculture has expanded worldwide. Numerous papers were published in the past 20 years comparing plant diseases in organic and conventional crops. Root diseases are generally less severe owing to greater soil health, whereas some foliar diseases can be problematic in organic agriculture. The soil microbial community and nitrogen availability play an important role in disease development and yield. Recently, the focus has shifted to optimizing organic crop production by improving plant nutrition, weed control, and plant health. Crop-loss assessment relating productivity to all yield-forming and -reducing factors would benefit organic production and sustainability evaluation. [ABSTRACT FROM AUTHOR]

This review surveys anthropological and other social research on bureaucratic documents. The fundamental insight of this literature is that documents are not simply instruments of bureaucratic organizations, but rather are constitutive of bureaucratic rules, ideologies, knowledge, practices, subjectivities, objects, outcomes, even the organizations themselves. It explores the reasons why documents have been late to come under ethnographic scrutiny and the implications for our theoretical understandings of organizations and methods for studying them. The review argues for the great value of the study of paper-mediated documentation to the study of electronic forms, but it also highlights the risk of an exclusive focus on paper, making anthropology marginal to the study of core bureaucratic practices in the manner of earlier anthropology. [ABSTRACT FROM AUTHOR]

Controversy persists regarding the utility of school-based interventions for obesity prevention and control and for related health promotion. This article reviews the pertinent evidence, based partly on a recent systematic review and meta-analysis by the author and colleagues. Of 64 relevant papers, 21 papers representing 19 distinct studies met quality criteria; half of these were published since 2000. Despite marked variation in measures, methods, and populations that handicap interpretation of this literature, evidence clearly demonstrated that school-based interventions had significant effects on weight. Thus available research evidence does present a case for school-based interventions. Despite the fact that such evidence is limited to date, the urgency of the obesity and diabetes epidemics cries out for action. Intervention is warranted on the basis of both extant evidence and common sense, with methodologically robust evaluation concomitantly to test our assumptions and verify our intuition. [ABSTRACT FROM AUTHOR]

Controversy persists regarding the utility of school-based interventions for obesity prevention and control and for related health promotion. This article reviews the pertinent evidence, based partly on a recent systematic review and meta-analysis by the author and colleagues. Of 64 relevant papers, 21 papers representing 19 distinct studies met quality criteria; half of these were published since 2000. Despite marked variation in measures, methods, and populations that handicap interpretation of this literature, evidence clearly demonstrated that school-based interventions had significant effects on weight. Thus available research evidence does present a case for school-based interventions. Despite the fact that such evidence is limited to date, the urgency of the obesity and diabetes epidemics cries out for action. Intervention is warranted on the basis of both extant evidence and common sense, with methodologically robust evaluation concomitantly to test our assumptions and verify our intuition. [ABSTRACT FROM AUTHOR]

The unique geometry of multilayer thin films, with layer thicknesses on the nanoscale, gives rise to a wide range of novel properties and behavior that are not observed in the bulk. The novel behavior is critically dependent on the microstructure of the films. This paper reviews the use of a range of transmission electron microscopy (TEM) techniques to elucidate the structure, chemistry, and properties of multilayer thin films. The paper includes a brief introduction to the technological applications to which multilayer thin films are suited, followed by a description of the various TEM techniques. The final section of the paper presents the application of these techniques to various rnultilayer thin film systems. [ABSTRACT FROM AUTHOR]

We outline roles of frequency-dependent selection (FDS) in coadaptation and coevolutionary change. Coadaptation and coevolution occur because correlational selection (CS) and correlated evolution couple many traits. CS arises from causal interactions between traits expressed in two or more interactors, which invariably involve different traits (signalers-receivers). Thus, the causes of CS are due to FDS acting on trait interactions. Negative FDS, a rare advantage, is often coupled to positive FDS generating complex dynamics and FD cycles. Neural mechanisms of learning and perception create analogous mutes by which traits are reinforced in cognitive and perceptual systems of interactors, substituting for positive FDS. FDS across all levels of biological organization is thus best understood as proximate causes that link interactors and shape genetic correlations within and among interactors on long timescales, or cognitive trait correlations within interactors on short timescales. We find rock-paper-scissors dynamics are common in nature. [ABSTRACT FROM AUTHOR]

Arthur F. Bentley and David Truman helped develop the so-called group interpretation of politics. They argued that all political activity is groups pursuing their interests against the interests of others. Despite their influence, Bentley and Truman are increasingly forgotten. This paper reviews their group interpretation, focusing on its philosophical basis. The paper argues for the continued significance and value of the group interpretation and of the pragmatist view of social science on which it is based. [ABSTRACT FROM AUTHOR]

This paper synthesizes research on linguistic practice and critically examines the legacy of Pierre Bourdieu from the perspective of linguistic anthropology. Bourdieu wrote widely about language and linguistics, but his most far reaching engagement with the topic is in his use of linguistic reasoning to elaborate broader sociological concepts including habitus, field, standardization, legitimacy, censorship, and symbolic power. The paper examines and relates habitus and field in detail, tracing the former to the work of Erwin Panofsky and the latter to structuralist discourse semantics. The principles of relative autonomy, boundedness, homology, and embedding apply to fields and their linkage to habitus. Authority, censorship, and euphemism are traced to the field, and symbolic power is related to misrecognition. And last, this chapter relates recent work in linguistic anthropology to practice and indicates lines for future research. [ABSTRACT FROM AUTHOR]

George Gabriel Stokes died just over 100 years ago, and it has been more than 150 years since he published his great 1847 paper on water waves. The work of Stokes' precursors, which informed his early publications of 1842-50, is described in the previous volume of the Annual Review of Fluid Mechanics (Craik 2004). Here I examine Stokes' papers and letters concerning water waves. [ABSTRACT FROM AUTHOR]

This paper examines the role of culture as a factor in enhancing the effectiveness of health communication. We describe culture and how it may be applied in audience segmentation and introduce a model of health communication planning-- McGuire's communication/persuasion model--as a framework for considering the ways in which culture may influence health communication effectiveness. For three components of the model (source, message, and channel factors), the paper reviews how each affects communication and persuasion, and how each may be affected by culture. We conclude with recommendations for future research on culture and health communication. [ABSTRACT FROM AUTHOR]

This paper is a short and nonexhaustive survey of some recent developments in optimal shape design (OSD) for fluids. OSD is an interesting field both mathematically and for industrial applications. Existence, sensitivity, and compatibility of discretizations are important theoretical issues. Efficient algorithmic implementations with low complexity are also critical. In this paper we discuss topological optimization, algorithmic differentiation, gradient smoothers, Computer Aided Design (CAD)-free platforms and shock differentiation; all these are applied to a multicriterion optimization for a supersonic business jet. [ABSTRACT FROM AUTHOR]

For over 20 years, charge-coupled devices (CCDs) have dominated most digital imaging applications and markets. Today, complementary metal oxide semiconductor (CMOS) arrays are displacing CCDs in some applications, and this trend is expected to continue. Low cost, low power, on-chip system integration, and high-speed operation are unique features that have generated interest in CMOS arrays. This paper reviews current CCD and CMOS sensor developments and related applications. We compare fundamental performance parameters common to these technologies and describe why the CCD is considered a mature technology, whereas CMOS arrays have significant room for growth. The paper presents custom CMOS pixel designs and related fabrication processes that address performance deficiencies of the CCD in high-performance applications. We discuss areas of development for future CCD and CMOS imagers. The paper also briefly reviews hybrid imaging arrays that combine the advantages of CCD and CMOS, producing better sensors than either technology alone can provide. [ABSTRACT FROM AUTHOR]

This paper presents a critical assessment of the field of common property. After discussing briefly the major findings and accomplishments of the scholarship on the commons, the paper pursues two strategies of critique. The first strategy of friendly critique accepts the basic assumptions of most writings on common property to show that scholars of commons have discovered far more variables that potentially affect resource management than is possible to analyze carefully. The paper identifies some potential means to address the problem of too many variables. The second line of critique proceeds differently. It asks how analyses of common property might change, and what they need to consider, if they loosen assumptions about sovereign selves and apolitical property rights institutions. My examination of these questions concludes this review with an emphasis on the need to (a) attend more carefully to processes of subject formation, and (b) investigate common property arrangements and associated subject positions with greater historical depth. [ABSTRACT FROM AUTHOR]

Recently, a number of papers about direct oxidation of methane and hydrocarbon in solid oxide fuel cells (SOFC) at relatively low temperatures (about 700°C) have been published. Even though the conversion of almost dry CH[sub4] at 1000°C on ceramic anodes was demonstrated more than 10 years ago, the reports about high-current densities for methane oxidation at such low temperatures are indeed surprising. Several papers indicate that a catalytic effect (due to the mixed ionic and electronic conductivity) of CeO[sub2-x] is partially responsible for this effect. However, this seems to contradict previous reports, and thus this issue deserves further analysis. [ABSTRACT FROM AUTHOR]

The release of previously secret internal tobacco industry documents has given the public health community unprecedented insight into the industry's motives, strategies, tactics, and data. The documents provide information that is not available from any other source and describe the history of industry activities over the past 50 years. The documents show that the tobacco industry has been engaged in deceiving policy makers and the public for decades. This paper begins with a brief history of the tobacco industry documents and describes the methodological challenges related to locating and analyzing an enormous number of poorly indexed documents. It provides an overview of selected important findings of document research conducted to date, including analyses of industry documents on nicotine and addiction, product design, marketing and promotion, passive smoke, and internal activities. The paper concludes with a discussion of the implications of tobacco document research for public health and the application of such research to fields other than tobacco control. [ABSTRACT FROM AUTHOR]

In addition to influencing care for patients enrolled in managed care plans, growth in managed care could lead to broad changes in the structure and functioning of the health care system that could ultimately influence care for all patients, even those not covered by managed care plans. This paper summarizes the mechanisms by which these effects could arise, including shifts in the types of services available in markets and changes in physician practice patterns. The paper summarizes available empirical evidence on broad-level effects of managed care, concluding that the literature supports the view that managed care can have generalized effects on health care spending, utilization patterns, and infrastructure, although existing literature has not clearly identified effects on health outcomes. [ABSTRACT FROM AUTHOR]

In this paper we review the properties of Lyman-break galaxies, namely starburst galaxies at high redshifts, approximately in the range 2.5 < z < 5, identified by the colors of their far ultraviolet spectral energy distribution around the 912 Å Lyman continuum discontinuity. The properties of forming galaxies in the young universe are very important to constrain the history of galaxy evolution and the formation of the Hubble sequence, and until recently, they have remained largely unexplored. The Lyman-break technique has broken an impasse in the exploration of galaxies at high redshift that lasted for about two decades, and within a few years has yielded large and well-controlled samples of star-forming, but otherwise normal, galaxies at z > 2.5, including ∼1000 spectroscopic redshifts and another few thousands of robust candidates. This dataset has allowed us an unprecedented look at fundamental properties of galaxies at 20% of the Hubble time or less. In this paper, we discuss the nature of the Lyman-break galaxies and their properties, including star-formation rate, stellar and total mass, chemical abundance, morphology, and interstellar medium (ISM) kinematics, and outline their contribution to the stellar content of the universe and their connection to the galaxies observed in the present-day universe. We also discuss what the properties of these galaxies, in particular their spatial clustering, imply about the mechanisms of galaxy formation and about the relationship between the underlying distribution of dark matter and the activity of star formation. [ABSTRACT FROM AUTHOR]

In 2001, nearly one billion dollars will be spent on statewide tobacco control programs, including those in California, Massachusetts, Arizona, and Oregon, funded by cigarette tax revenues, and the program in Florida, funded by the state's settlement with the tobacco industry. With such large expenditures, it is imperative to find out whether these programs are working. This paper reviews the effectiveness of the statewide tobacco control programs in California, Massachusetts, Arizona, Oregon, and Florida. It focuses on two aspects of process evaluation—the funding and implementation of the programs and the tobacco industry's response, and four elements of outcome evaluation—the programs' effects on cigarette consumption, adult and youth smoking prevalence, and protection of the public from secondhand smoke. The paper formulates general lessons learned from these existing programs and generates recommendations to improve and inform the development and implementation of these and future programs. [ABSTRACT FROM AUTHOR]

The paper discusses the use of latent variables in psychology and social science research. Local independence, expected value true scores, and nondeterministic functions of observed variables are three types of definitions for latent variables. These definitions are reviewed and an alternative “sample realizations” definition is presented. Another section briefly describes identification, latent variable indeterminancy, and other properties common to models with latent variables. The paper then reviews the role of latent variables in multiple regression, probit and logistic regression, factor analysis, latent curve models, item response theory, latent class analysis, and structural equation models. Though these application areas are diverse, the paper highlights the similarities as well as the differences in the manner in which the latent variables are defined and used. It concludes with an evaluation of the different definitions of latent variables and their properties. [ABSTRACT FROM AUTHOR]

At nuclear power reactors around the United States, quantities of spent or irradiated nuclear fuel are growing while owner-operator companies await the approval of a permanent storage facility. Some reactors have run out of space in their cooling pools and have had to resort to dry cask storage. The first half of this paper looks at the policy history of interim storage in the United States, discusses the current storage status at individual reactors, and then reviews the technologies available to deal with it. The second half of the paper considers the different options for dealing with this hazardous material in the interim, before a permanent high-level nuclear waste repository is opened, and examines the safety, security, transportation, economic, political, and other issues that bear on the choice of option. [ABSTRACT FROM AUTHOR]

Investigators often gather repeated measures on study subjects to directly measure how a subject's response changes with changes in explanatory variables. This paper focuses on several statistical issues related to assessing change with longitudinal and clustered binary data. Many popular approaches for analyzing repeated binary outcomes measure cross-sectional or between-subject, rather than within-subject, effects of covariates. The class of models known as cluster specific measures within-subject effects of covariates on responses but are subject to additional statistical complications. It is useful to decompose covariates into between- and within-cluster components. This paper describes several approaches that yield consistent estimates of the within-subject covariate effects of interest. Example data from three studies illustrate the results. [ABSTRACT FROM AUTHOR]

This review focuses on papers published since 2000 on the topic of the properties of solutes in water. More specifically, it evaluates the state of the art of our understanding of the complex relationship between the shape of a hydrophobe and the hydrophobic effect. To highlight this, we present a selection of references covering both empirical and molecular dynamics studies of small (molecular-scale) solutes. These include empirical studies of small molecules, synthetic hosts, crystalline monolayers, and proteins, as well as in silico investigations of entities such as idealized hard and soft spheres, small solutes, hydrophobic plates, artificial concavity, molecular hosts, carbon nanotubes and spheres, and proteins. [ABSTRACT FROM AUTHOR]

Stuart Ross Taylor, MSc (University of New Zealand), PhD (Indiana University), ScD (University of Oxford), FAA, AC, always called Ross, grew up on a farm near Ashburton, New Zealand. Ross has worked on a wide variety of topics in trace element geochemistry, including the composition and evolution of the Moon, the continental crust, tektites, impact glasses, and island arc rocks. In 1969 he carried out the first chemical analysis of the first returned lunar sample at NASA in Houston. He has published 10 books and 240 papers in scientific journals. He was awarded the V.M. Goldschmidt Award of the Geochemical Society in 1993. In 1994 he was elected a Foreign Associate of the National Academy of Sciences. In 1998, he was awarded the Leonard Medal of the Meteoritical Society, in 2002 the Bucher Medal of the American Geophysical Union, and in 2012 the Shoemaker Distinguished Lunar Scientist Medal of the NASA Lunar Science Institute. Asteroid 5670 is named Rosstaylor. [ABSTRACT FROM AUTHOR]

Nuclear forensic science seeks to identify the origin of nuclear materials found outside regulatory control. It is increasingly recognized as an integral part of a robust nuclear security program. This review highlights areas of active, evolving research in nuclear forensics, with a focus on analytical techniques commonly employed in Earth and planetary sciences. Applications of nuclear forensics to uranium ore concentrates (UOCs) are discussed first. UOCs have become an attractive target for nuclear forensic researchers because of the richness in impurities compared to materials produced later in the fuel cycle. The development of chronometric methods for age dating nuclear materials is then discussed, with an emphasis on improvements in accuracy that have been gained from measurements of multiple radioisotopic systems. Finally, papers that report on casework are reviewed, to provide a window into current scientific practice. [ABSTRACT FROM AUTHOR]

This paper explores what it means to do a sociology of families, that is, one that acknowledges and considers a wider array of family forms than typically has been explored. We begin by reviewing the existing sociological research on a range of alternative family forms, ultimately focusing on older-parent, adoptive, same-sex, and multiracial families. We describe and critically assess four theoretical approaches to examining family forms-family structure, evolutionary, characteristics, and context-and their implications for children, and we discuss the utility of an approach that views family characteristics in social context. We also recommend that instead of using alternative family forms primarily or solely as counterfactuals to the so-called traditional family, researchers should compare alternative family forms to each other, noting theoretical implications for commonalities and differences found among these groups. We call for additional research on alternative families, noting its importance for sociology, family studies, and public policy. [ABSTRACT FROM AUTHOR]

Scientific misconduct has been defined as fabrication, falsification, and plagiarism. Scientific misconduct has occurred throughout the history of science. The US government began to take systematic interest in such misconduct in the 1980s. Since then, a number of studies have examined how frequently individual scientists have observed scientific misconduct or were involved in it. Although the studies vary considerably in their methodology and in the nature and size of their samples, in most studies at least 10% of the scientists sampled reported having observed scientific misconduct. In addition to studies of the incidence of scientific misconduct, this review considers the recent increase in paper retractions, the role of social media in scientific ethics, several instructional examples of egregious scientific misconduct, and potential methods to reduce research misconduct. [ABSTRACT FROM AUTHOR]

To prevent the intergenerational transfer of obesity and end the current epidemic, interventions are needed across the early life stages, from preconception to prenatal to infancy through the age of 2 years. The foundation for obesity is laid in early life by actions and interactions passed from parent to child that have long-lasting biologic and behavioral consequences. The purpose of this paper is to examine the best evidence about (a) factors in parents and offspring that promote obesity during the early life stages, (b) the social determinants and dimensions of obesity in early life, (c) promising and effective interventions for preventing obesity in early life, and (d) opportunities for future research into strategies to disrupt the intergenerational cycle of obesity that begins early in life. The pathway for halting the intergenerational obesity epidemic requires the discovery and development of evidence-based interventions that can act across multiple dimensions of influence on early life. [ABSTRACT FROM AUTHOR]

Conventional hydroelectric generation uses a renewable energy source and currently supplies ∼10% of the annual output of electricity in the United States and ∼20% of electricity generated worldwide. To provide a significant contribution to sustainable development, the hydropower industry must address a variety of environmental concerns, including water quality and fish passage issues. The paper discusses new technologies for turbine design and control systems to improve dissolved oxygen levels in turbine discharges and survival of fish during turbine passage. The paper describes development, testing, and test results for these technologies, with an emphasis on collaboration of stakeholders and balance between environmental stewardship and economical power production. [ABSTRACT FROM AUTHOR]

This paper focuses on the desirability, from an economic perspective, of setting fixed and relatively short-term targets and timetables, such as those contained in the Kyoto Protocol, as a means of achieving longer-term climate change mitigation goals. The paper argues that whatever long-term policy goals are adopted, greater flexibility lowers implementation costs. Lower implementation costs, in turn, increases the likelihood that the policies will actually be followed and the goals achieved. Importantly, the Kyoto Protocol incorporates key elements of both “what” and “where” flexibility. That is, the “Kyoto basket” includes all six of the major greenhouse gases plus sinks, and the Protocol incorporates several mechanisms that allow emission reductions to take place at the least-cost geographic location, regardless of nation-state boundaries. The Protocol also provides substantial “how” flexibility in the sense that countries can use a variety of means to achieve domestic policy goals. However, the Protocol does not allow emission reductions to take place at a point in time when they can be achieved at lowest cost as long as they are consistent with the long-term environmental goals (“when” flexibility). Additionally, it does not allow the use of efficient price-based policy instruments to define targets and, thereby, balance environmental goals and compliance costs (which could be thought of as a broader version of “when” flexibility). Instead, the Protocol relies exclusively on strict, short term quantity targets. The relative inflexibility of the Protocol with respect to the timing of reductions and definitions of the targets may derive, in part, from a misplaced analogy between the global warming issue and the highly successful effort to phase out CFCs under the Montreal Protocol. The lack of when flexibility may be a key barrier to achieving the broader goals of the K... [ABSTRACT FROM AUTHOR]

Functional data have been both the least used and the least understood class of data in systematics. Compared to the use of morphological features from DNA sequences to gross structural characters, patterns of distribution, and even ecological and behavioral attributes of organisms, functional characters have not been generally thought of as useful for resolving systematic and historical questions. The current status of functional data in systematics is due to three primary factors, both historical and practical. First, current research in systematics developed primarily out of the nineteenth century morphological tradition while the analysis of organismal function was centered in physiological and experimental embryological research. At the turn of the century these two research traditions, initially complementary, diverged. While several authors have debated the severity of the divergence in research between morphologists (interested in the comparative analysis of structure, its development, and phylogeny) and experimental biologists (interested in function, physiology, or uses of structures) (5, 6, 102), there is little doubt that these two research areas diverged in the early part of this century and have remained largely separate. Second, functional data are hard to obtain on a diversity of taxa: Gathering a range of experimental data on even one small clade is time consuming, and conducting manipulative experiments to understand causal relationships only adds to the difficulty of comparative functional analyses. Third, many so-called "functional" analyses and discussions of the import of function for systematics are in fact purely morphological. The adjective "functional" has acquired a cachet: It sounds quantitative, technical, and sophisticated. As a consequence, it is frequently used by papers in which there is no resemblance of a true functional analysis, where organismal function is directly measured and compared with measured function in other clades. The valid heuristic use of functional ideas should not be a substitute for direct measurement. A key aim of this paper is to suggest that functional data are in fact critical to understanding five important issues in systematics. Despite difficulties in gathering functional data, the development of even a small number of well-understood case studies would greatly enhance our appreciation of (a; historical patterns to functional transformation, (b) the use of functional characters to define monophyletic clades. (c) the causal basis of character distributions on cladograms, (d) the extent to which changes in structural, functional, and behavioral characters are historically congruent, and the extent of evolutionary conservatism at any particular level of organismal design, and (e) general patterns and principles in the evolution of form and function. [ABSTRACT FROM AUTHOR]

Researchers in horticulture, forestry, entomology, plant physiology, and ecology have all added significantly to the literature on flower and fruit abscission. Consequently, the data on this topic range from the physiological details of the abscission process to pertinent plant-animal interactions. This breadth of knowledge is a luxury not often afforded to ecological and evolutionary studies. Unfortunately, communication among disciplines is limited. Thus in this paper I attempt to organize and synthesize the diverse literature on flower and fruit abortion in order to help focus future ecological research. The literature review is not exhaustive but should provide access to the remaining literature. This paper has two additional objectives: to identify the proximate factors that limit fruit and seed production between anthesis and dispersal, and to determine if flower and fruit abscission provide plants with some degree of control over the number and quality of their offspring. [ABSTRACT FROM AUTHOR]