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An abstract of the research paper "Different memory T cell phenotypes are elicited by Ad5 and rare adenoviruses," by P. Penaloza and colleagues is presented.

An abstract of the research paper "Evaluation of the dual IFNγ/IL-2 fluorospot-assay with flow cytometry for detection of HLA-restricted HIV-specific T-cell responses in HIV controllers," by N. Keane and colleagues is presented.

An abstract of the research paper "Assessment of T cell immune responses towards HIV-1 epitopes designed by reverse immunogenetic approach: proof-of-concept in HIV+ Cameroonian children," by E. Nemes and colleagues is presented.

An abstract of the research paper "Infrequent, low magnitude HIV-specific T cell responses in HIV-uninfected participants in the 1% tenofovir microbicide gel trial (CAPRISA004)," by W. A. Burgers and colleagues is presented.

An abstract of the research paper "T cell immune quiescence as a contributor to resistance to infection among HIV Exposed Seronegative (HESN) commercial sex workers from Nairobi, Kenya," by K. R. Fowke and colleagues is presented.

An abstract of the research paper "Impact of the innate environment on maintaining memory T-cell numbers in the female genital tract: implications for mucosal vaccine efficacy?," by S. Dabee and colleagues is presented.

An abstract of the research paper "HIV triggers immunoregulatory dendritic cells and regulatory T cells through the non-canonical NF-kB pathway," by O. Manches and colleagues is presented.

An abstract of the conference paper "Two independent functions of Vγ2Vδ2 T cells discriminated by CD16 during HIV-1 infection," by H. Liang and colleagues is presented.

An abstract of the research paper "Regulatory B cells are induced in untreated HIV-1 infection and suppress HIV-1 specific T cell responses," by J. Liu and colleagues is presented.

An abstract of the conference paper "Quality of T-cell responses versus reduction in viral load: results from an exploratory phase II clinical study of Vacc-4x, a therapeutic HIV vaccine" by P.F. McKay and colleagues is presented.

An abstract of the conference paper "Active regulatory T-cells contribute to broadened T-cell repertoire diversity in ivIg-treated SLE patients," by several researchers including, Nuno Costa, Ana E. Pires, and Ana M. Gabriel is presented.

An abstract of the conference paper "Adipocytes from the infrapatellar fat pad of OA patients modulate CD4+ T cell cytokine production," by several researchers including, Andreea Ioan-Facsinay, Joanneke C. Kwekkeboom, and Margreet Kloppenburg is presented.

An abstract of the conference paper "Extensive natural killer cell receptor phenotyping on NK and T cells discloses differences in RA and PsA, potentially mirroring diverse immunoregulatory functions," by several researchers including, Harry Dolstra, Frank Preijers, and Jan Spanholtz is presented.

An abstract of the conference paper "The blood of healthy individuals exhibits CD8 T cells with a highly altered TCR V&#00DF repertoire but with an unmodified phenotype," by several researchers including, Nicolas Degauque, Caroline Ballet, and Yohann Foucher is presented.

An abstract of the conference paper "CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung," by several researchers including, Nicolas Glaichenhaus, Cyrille Mionnet, and Valérie Julia is presented.

An abstract of the conference paper "Alloantigenic recognition properties of CD8+ regulatory T cells," by several researchers including, Elodie Picarda, Ignacio Anegon, and Carole Guillonneau is presented.

An abstract of the conference paper "Single-cell gene profiling of human regulatory T cell subsets in human graft-versus-host disease," by several researchers including, Shen Dong, Sylvie Maiella, and Yuanyu Pang is presented.

An abstract of the conference paper "Identification of an osteoclastogenic CD4+ T cell population producing IL-17 and TNF&#03B1," by several researchers including, Hans Yssel, Claudine Blin-Wakkach, and Abdelilah Wakkach is presented.

An abstract of the conference paper "Lyoplate-based multiparameter flow cytometry for the analysis of T cell subsets in human immuno-monitoring studies," by several researchers including, Federica Villanova, Paola Di Meglio, and Susanne Heck is presented.

An abstract of the conference paper "CD4+FOXP3+ regulatory T cells are abundantly present in inflamed muscle of patients with juvenile dermatomyositis," by Yvonne Vercoulen and colleagues is presented.

An abstract of the conference paper "Increased stimulatory capacity of antigen presenting cells at the site of autoimmune inflammation interferes with regulatory T cell function," by Femke Van Wijk and colleagues is presented.

An abstract of the conference paper "PD-1/PD-L1 signaling in JIA synovial regulatory T cell function," by Sytze de Roock and colleagues is presented.

An abstract of the conference paper "An Altered Peptide Ligand derived from heatshock protein 60 induces regulatory T cells in JIA patients and suppresses adjuvant-induced arthritis," by Elsy Chall and colleagues, is presented.

An abstract of the conference paper "Regulatory T cells from the inflamed joints of patients with juvenile idiopathic arthritis (JIA) are dysregulated and display a pro-inflammatory profile," by Kiran Nistala and colleagues is presented.

An abstract of the research paper titled," Cloned the Human T-cell leukemia virus type 1 (HTLV-1) modulates alternative splicing in CD4+ T cells in vivo," is presented.

An abstract of the research paper titled,"The Human T-cell leukemia virus type 1 (HTLV-1) modulates alternative splicing in CD4+ T cells in vivo," is presented.

An abstract of the research paper titled,"Predominant role of Tax sumoylation in Tax-induced NF-kB activation in T cells," is presented.

An abstract of the research paper titled,"Control of reactive oxygen species (ROS) production and T-cell turnover by the Human T-cell leukemia virus type 13 (HTLV-p13)," is presented.

An abstract of the research paper titled," TP53 and p16INK4A mutations in adult-T cell leukemia/lymphoma (ATL) in Bahia (Brazil) ," is presented.

An abstract of the research paper titled," Cytoplasmic and nuclear events controlling Tax-mediated activation of the NF-kB pathway: involvement of TNF-receptor associated protein 2(TAB2), IKKgamma/NEMO and calreticulin ," is presented.

An abstract of the research paper titled "Inverse Correlation Between Tax and CD25 Expressions in HTLV-1 Infected CD4 T-cells In-Vivo," by Kenyta Tezuka, Runze Xun, Mami Tei Takaharu Ueno and others is presented.

An abstract of the research paper titled "HTLV-1 Propels Thymic Human T-Cell Development in "Human Immune System" Rag2-/- IL-2R gamma c-/- Mice" presented by Nicolas Gadot, Louis Gazzolo, Julien Villaudy, Jean-Yves Scoazec and others is presented.

An abstract of the research paper titled " Activation of HTLV-1 Expression in Chronically-Infected CD4+ T cells: Mechanisms and Implications for Pathogenesis," by Alison Swaims, Hsin-Ching Lin, Peter Simon, Celine Granier, Yingyu Zhang, Arthur Roberts and Satish Devadas is presented.

The article presents an abstract of a research paper that analyzes the effect of Rituximab treatment on T cells, submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases in Sitges-Barcelona, Spain from December 1-3, 2010.

The article presents an abstract of a research paper that examines the expression of different A-kinase Anchoring Proteins (AKAPs) in T cells isolated from systemic lupus erythematosus (SLE) T cells, submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases in Sitges-Barcelona, Spain from December 1-3, 2010.

The article presents an abstract of research paper on human regulatory T cell subsets submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases held at Barcelona, Spain, on December 1-3, 2010.

The article presents an abstract of research paper on T-cell receptor submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases held at Barcelona, Spain, on December 1-3, 2010.

The article presents an abstract of research paper on human T-cell subsets submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases held at Barcelona, Spain, on December 1-3, 2010.

The article presents an abstract of research paper on immunosurveillance by gamma delta T cells submitted at the 5th European Workshop on Immune-Mediated Inflammatory Diseases held at Barcelona, Spain, on December 1-3, 2010.

A conference paper on inferring gene regulatory networks from classified microarray data is presented. The network inference method is based on the optimal network search algorithm proposed by Ott. ROC analysis of networks recovered from synthetic data provides a measure of the performance of the method. The method shows that distinct sub-networks associated with AML and with T-cell responses emerge.

Background: The importance of the malignant cell environment to its growth and survival is becoming increasingly apparent, with dynamic cross talk between the neoplastic cell, the leukocyte infiltrate and the stroma. Most cancers are accompanied by leukocyte infiltration which, contrary to an anticipated immuno-protective role, could be contributing to tumour development and cancer progression. Epstein-Barr virus (EBV) associated cancers, including nasopharyngeal carcinoma and Hodgkin's Disease, show a considerable leukocyte infiltration which surrounds the neoplastic cells, raising the questions as to what role these cells play in either restricting or supporting the tumour and what draws the cells into the tumour. In order to begin to address this we have studied a transgenic model of multistage carcinogenesis with epithelial expression of the EBV primary oncoprotein, latent membrane protein 1 (LMP1). LMP1 is expressed particularly in the skin, which develops a hyperplastic pathology soon after birth. Results: The pathology advances with time leading to erosive dermatitis which is inflamed with a mixed infiltrate involving activated CD8+ T-cells, CD4+ T-cells including CD4+/CD25+/FoxP3+ Treg cells, mast cells and neutrophils. Also significant dermal deposition of immunoglobulin-G (IgG) is observed as the pathology advances. Along with NF-kappaB activation, STAT3, a central factor in inflammation regulation, is activated in the transgenic tissue. Several inflammatory factors are subsequently upregulated, notably CD30 and its ligand CD153, also leukocyte trafficking factors including CXCL10, CXCL13, L-selectin and TG1β1, and inflammatory cytokines including IL-1β, IL-3 and the murine IL-8 analogues CXCL1, CXCL2 and CXCL5-6, amongst others. The crucial role of mature T- and/or B-lymphocytes in the advancing pathology is demonstrated by their elimination, which precludes mast cell infiltration and limits the pathology to an early, benign stage. Conclusions: LMP1 can lead to the activation of several key factors mediating proliferation, angiogenesis and inflammation in vivo. With the initiation of an inflammatory programme, leukocyte recruitment follows which then itself contributes to the progressing pathology in these transgenic mice, with a pivotal role for B-and/or T-cells in the process. The model suggests a basis for the leukocyte infiltrate observed in EBV-associated cancer and its supporting role, as well as potential points for therapeutic intervention. [ABSTRACT FROM AUTHOR]