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Your search keyword '"Barnes, John"' showing total 1 results
Start Over Author "Barnes, John" Publication Year Range Last 50 years Region laos Publisher centers for disease control & prevention (cdc)
1 results on '"Barnes, John"'

1. Antiviral Drug-Resistant Influenza B Viruses Carrying H134N Substitution in Neuraminidase, Laos, February 2016.

Author

Baranovich, Tatiana, Vongphrachanh, Phengta, Ketmayoon, Pakapak, Sisouk, Thongchanh, Chomlasack, Khampheng, Khanthamaly, Viengphone, Nguyen, Ha Thuy, Mishin, Vasiliy P., Marjuki, Henju, Barnes, John R., Garten, Rebecca J., Stevens, James, Wentworth, David E., and Gubareva, Larisa V.

Subjects
INFLUENZA B virus, OSELTAMIVIR, NEURAMINIDASE, HISTIDINE
Abstract

In February 2016, three influenza B/Victoria/2/87 lineage viruses exhibiting 4- to 158-fold reduced inhibition by neuraminidase inhibitors were detected in Laos. These viruses had an H134N substitution in the neuraminidase and replicated efficiently in vitro and in ferrets. Current antiviral drugs may be ineffective in controlling infections caused by viruses harboring this mutation. [ABSTRACT FROM AUTHOR]

Published
2017
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