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Start Over Author "Josa-Culleré, Laia" Publication Year Range Last 50 years Publisher georg thieme verlag stuttgart
1 results on '"Josa-Culleré, Laia"'

1. Stereoselectivity in the Reduction of Bicyclic Tetramates.

Author

Josa-Culleré, Laia, Moloney, Mark G., and Thompson, Amber L.

Subjects
*STEREOSELECTIVE reactions, *BICYCLIC compounds, *CHEMICAL reduction, *LACTAMS, *PYROGLUTAMIC acid
Abstract

The reduction of bicyclic tetramates can be achieved with high levels of diastereocontrol, but small changes in the substitution of the bicyclic lactam system can lead to changes in the steric bias of the concave/convex system. The tetramates and pyroglutamates prepared in this work exhibited limited antibacterial activity. [ABSTRACT FROM AUTHOR]

Published
2016
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