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Your search keyword '"Gu, Yue"' showing total 18 results
Start Over Author "Gu, Yue" Publication Year Range Last 50 years Publisher hindawi limited
18 results on '"Gu, Yue"'

1. Shear-Induced ITGB4 Promotes Endothelial Cell Inflammation and Atherosclerosis

Author

Kong, Xiangquan, primary, Chen, Siyu, additional, Luo, Shuai, additional, Chen, Aiqun, additional, Wang, Liguo, additional, Tang, Haoyue, additional, Wang, Feng, additional, Wang, Zhimei, additional, Gao, Xiaofei, additional, Zuo, Guangfeng, additional, Zhou, Wenying, additional, Gu, Yue, additional, Ge, Zhen, additional, and Zhang, Junjie, additional

Published
2022
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2. PCAF Accelerates Vascular Senescence via the Hippo Signaling Pathway

Author

Kong, Chaohua, primary, Wang, Dongchen, additional, Wang, Feng, additional, Lv, Yifei, additional, Zhou, Wenying, additional, Ye, Peng, additional, Gu, Yue, additional, Jiang, Xiaomin, additional, Zhu, Linlin, additional, Ge, Zhen, additional, Chao, Yuelin, additional, and Chen, Shaoliang, additional

Published
2022
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8. Plasma Small Extracellular Vesicle-Carried miRNA-501-5p Promotes Vascular Smooth Muscle Cell Phenotypic Modulation-Mediated In-Stent Restenosis

Author

Gao, Xiao-Fei, primary, Wang, Zhi-Mei, additional, Chen, Ai-Qun, additional, Wang, Feng, additional, Luo, Shuai, additional, Gu, Yue, additional, Kong, Xiang-Quan, additional, Zuo, Guang-Feng, additional, Jiang, Xiao-Min, additional, Ding, Guan-Wen, additional, Chen, Yan, additional, Ge, Zhen, additional, Zhang, Jun-Jie, additional, and Chen, Shao-Liang, additional

Published
2021
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17. Bioguided Fraction and Isolation of the Antitumor Components from Phyllanthus niruri L.

Author

Zheng, Zhi-Zhong, Chen, Liang-Hua, Liu, Shao-Song, Deng, Yuan, Zheng, Guo-Hua, Gu, Yue, and Ming, Yan-Lin

Subjects
ANTINEOPLASTIC agents, BIOLOGICAL assay, CELL culture, CELL lines, ANALYTICAL chemistry, CHROMATOGRAPHIC analysis, CISPLATIN, ENZYME inhibitors, MASS spectrometry, MEDICINAL plants, MOLECULAR structure, NUCLEAR magnetic resonance spectroscopy, RESEARCH funding, T-test (Statistics), TOXICITY testing, PLANT extracts, DESCRIPTIVE statistics
Abstract

Phyllanthus niruri L., a well-known medicinal plant, has been used as a folk antitumor remedy in the worldwide scale. However, the antitumor components in P. niruri have not been reported. In order to verify the antitumor components of P. niruri and the plants which have the high content of these components, we isolated the antitumor components with bioguided fraction and isolation, by different chromatographic methods from the ethyl acetate fraction of P. niruri., and identified them as ethyl brevifolincarboxylate and corilagin by 1H-NMR, 13C-NMR, 2D-NMR, and mass spectrometric analyses. Cell cytotoxicity assays showed that corilagin has broad-spectrum antitumor activity, a better antitumor potential, and lower toxicity in normal cells. Besides, the coefficient of drug interaction (CDI) of 10 μM corilagin and 20 μM cDDP reached up to 0.77, which means corilagin can promote the antitumor activity of cDDP. Furthermore, by the extensive screening among 10 species of plants reported to contain corilagin, we found that Dimocarpus longan Lour. has the maximum content of corilagin. In conclusion, corilagin is the major active antitumor composition in P. niruri. L. on HCC cells and has high content in D. longan. [ABSTRACT FROM AUTHOR]

Published
2016
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