1. Acupuncture of different treatment frequencies in knee osteoarthritis: a pilot randomised controlled trial.
- Author
-
Lu-Lu Lin, Jian-Feng Tu, Li-Qiong Wang, Jing-Wen Yang, Guang-Xia Shi, Jin-Ling Li, Na Zhang, Jia-Kai Shao, Xuan Zou, Cun-Zhi Liu, Lin, Lu-Lu, Tu, Jian-Feng, Wang, Li-Qiong, Yang, Jing-Wen, Shi, Guang-Xia, Li, Jin-Ling, Zhang, Na, Shao, Jia-Kai, Zou, Xuan, and Liu, Cun-Zhi
- Subjects
- *
OSTEOARTHRITIS treatment , *KNEE diseases , *PILOT projects , *PAIN measurement , *ACUPUNCTURE , *TREATMENT effectiveness , *RANDOMIZED controlled trials , *QUESTIONNAIRES , *STATISTICAL sampling - Abstract
This 16-week randomised controlled trial (8-week treatment followed by 8-week follow-up) evaluated the symptomatic improvement in patients with knee osteoarthritis on 3 sessions per week of acupuncture (TSWA) compared to 1 session per week of acupuncture (OSWA). Sixty participants were randomised to either the TSWA or the OSWA group in a 1:1 ratio. The primary outcome was response rate, defined as the percentage of participants achieving ≥2 points decrease on the numerical rating scale (NRS) and ≥6 points decrease in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) function score at week 8 compared with baseline. Additional outcomes included response rates at weeks 4 and 16, NRS, WOMAC, Patient Global Assessment, 12-item Short Form Health Survey (SF-12), and treatment credibility and expectancy. No significant difference was seen in response rate between TSWA and OSWA groups at week 8 (64.7% vs 50.0%; difference, 14.7 percentage points [95% CI, -10.1 to 39.4 percentage points], P = 0.435). At weeks 4 and 16, the TSWA group had higher response rates than the OSWA group (week-4: difference, 44.7 percentage points [95% CI, 23.2-66.1 percentage points], P = 0.001; week-16: difference, 46.0 percentage points [95% CI, 24.4-67.6 percentage points], P < 0.001). Participants in the TSWA group experienced significantly greater improvements in NRS, WOMAC function, and Patient Global Assessment than those in the OSWA group. There were no significant between-group differences in WOMAC stiffness and SF-12. In summary, TSWA immediately improved knee pain and dysfunction compared with OSWA. In addition, the benefit of TSWA persists throughout follow-up. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF