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Your search keyword '"Barnes, John"' showing total 1 results
Start Over Author "Barnes, John" Topic amino acid deletion Publication Year Range Last 50 years Publisher wiley-blackwell
1 results on '"Barnes, John"'

1. In‐field detection and characterization of B/Victoria lineage deletion variant viruses causing early influenza activity and an outbreak in Louisiana, 2019.

Author

Shu, Bo, Wilson, Malania M., Keller, Matthew W., Tran, Ha, Sokol, Theresa, Lee, Grace, Rambo‐Martin, Benjamin L., Kirby, Marie K., Hassell, Norman, Haydel, Danielle, Hand, Julie, Wentworth, David E., and Barnes, John R.

Subjects
COVID-19, INFLUENZA, VIRAL vaccines, AMINO acids, HEMAGGLUTININ, REVERSE transcriptase polymerase chain reaction
Abstract

Background: In 2019, the Louisiana Department of Health reported an early influenza B/Victoria (B/VIC) virus outbreak. Method: As it was an atypically large outbreak, we deployed to Louisiana to investigate it using genomics and a triplex real‐time RT‐PCR assay to detect three antigenically distinct B/VIC lineage variant viruses. Results: The investigation indicated that B/VIC V1A.3 subclade, containing a three amino acid deletion in the hemagglutinin and known to be antigenically distinct to the B/Colorado/06/2017 vaccine virus, was the most prevalent circulating virus within the specimens evaluated (86/88 in real‐time RT‐PCR). Conclusion: This work underscores the value of portable platforms for rapid, onsite pathogen characterization. [ABSTRACT FROM AUTHOR]

Published
2024
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