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44 results on '"Donati, Daniele"'

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2. Neutralizing Antibodies against SARS-CoV-2 Beta and Omicron Variants Inhibition Comparison after BNT162b2 mRNA Booster Doses with a New PETIA sVNT Assay

3. Diritto e amministrazione della sanità - Approfondimenti a.a. 2020-2021

4. Diritto e amministrazione della sanità - Approfondimenti a.a. 2019-2020. Il SSN alla prova dell'emergenza COVID-19. Profili problematici e prime riflessioni sull'anno della pandemia

5. The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

6. The opinions and feelings about their educational needs and role of familial caregivers of parkinson’s disease patients: A qualitative study

7. Novel stereocontrolled addition of allylmetal reagents to alpha-imino esters: efficient synthesis of chiral tetrahydroquinoline derivatives

8. Synthesis of novel pentacyclic [beta]-lactam antibacterial agents

9. La digitalizzazione del patrimonio culturale. Caratteri strutturali e valore dei beni, tra disciplina amministrativa e tutela opere d’ingegno

10. New Policies and Practices for European Sharing Cities

12. Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515

15. Abstract 4843: NMS-P293, a PARP-1 selective inhibitor with no trapping activity and high CNS penetration, possesses potent in vivo efficacy and represents a novel therapeutic option for brain localized metastases and glioblastoma

16. Abstract 4785: NMS-E668, a highly potent orally available RET inhibitor with selectivity towards VEGFR2 and demonstrated antitumor efficacy in multiple RET-driven cancer models

18. Abstract 1223: NMS-P293, a novel potent and selective PARP-1 inhibitor with high antitumor efficacy and tolerability

19. Entrectinib, a Pan–TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

20. Abstract A149: NMS-P945, a highly active payload for antibody drug conjugates generation

21. Abstract 1638: Preclinical characterization of the novel TTK kinase inhibitor S81694 for the treatment of triple negative breast cancer

23. Abstract 822: Thienoindoles, a novel class of DNA minor groove alkylating agents highly suited for the generation of novel antibody drug conjugates (ADCs)

25. NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases

26. Abstract 3259: Novel isoquinolinone derivatives with dual PARP-1/PARP-3 inhibitory activity are highly active against pTEN mutated colorectal cancer and glioblastoma models..

27. Abstract 2097: Targeting aneuploidy with NMS-P153, a tight binder inhibitor of the spindle assembly checkpoint MPS1 (TTK) kinase.

28. Abstract 2091: Identification of a highly potent, selective and orally available RET inhibitor with antitumor efficacy in RET-dependent tumor models.

29. Abstract 3754: Characterization of NMS-P285, a new highly selective and potent BRAF inhibitor

30. Abstract 1775: Characterization of new highly selective and potent PARP-1 inhibitors

31. Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death

32. Abstract A232: In vitro and in vivo activity of NMS-E628 against ALK mutations resistant to Xalkori.

34. Abstract B241: Targeting the mitotic checkpoint with NMS-P153, a novel MPS1 kinase inhibitor.

35. Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase

36. Abstract 691: In vitro and in vivo characterization of selective orally available Parp-1 inhibitors with demonstrated antitumor efficacy in BRCA negative cancer models

37. Abstract 2522: Identification and characterization of new highly selective and potent BRAF inhibitors

40. Synthesis of novel pentacyclic -lactam antibacterial agents

41. The digital art paradox: understanding its issues and dynamics

42. The opinions and feelings about their educational needs and role of familial caregivers of Parkinson's Disease patients: a qualitative study.

43. BRASS score and complex discharge: a pilot study

44. Novel stereocontrolled addition of allylmetal reagents to alpha-imino esters: efficient synthesis of chiral tetrahydroquinoline derivatives.

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