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30 results on '"Kara, Naveed"'

1. Effectiveness of septoplasty compared to medical management in adults with obstruction associated with a deviated nasal septum: the NAIROS RCT

Author

Carrie, Sean, primary, Fouweather, Tony, additional, Homer, Tara, additional, O’Hara, James, additional, Rousseau, Nikki, additional, Rooshenas, Leila, additional, Bray, Alison, additional, Stocken, Deborah D, additional, Ternent, Laura, additional, Rennie, Katherine, additional, Clark, Emma, additional, Waugh, Nichola, additional, Steel, Alison J, additional, Dooley, Jemima, additional, Drinnan, Michael, additional, Hamilton, David, additional, Lloyd, Kelly, additional, Oluboyede, Yemi, additional, Wilson, Caroline, additional, Gardiner, Quentin, additional, Kara, Naveed, additional, Khwaja, Sadie, additional, Leong, Samuel Chee, additional, Maini, Sangeeta, additional, Morrison, Jillian, additional, Nix, Paul, additional, Wilson, Janet A, additional, and Teare, M Dawn, additional

Published
2024
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2. Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial

Author

Soiza, Roy L., Brittain-Long, Robin, Scicluna, Chiara, Edwards, Carole, Mackay, Lynn, D'Allesandro, Mariella, Nicol, Amy, Norris, Karen, Mann, Sandra, Lawrence, Heather, Valentine, Ruth, Viljoen, Marianne Elizabeth, Pretswell, Carol H., Nicholls, Helen, Munsoor, Imrozia, Meyrick, Agnieszka, Kyriakidou, Christina, Iyengar, Shalini, Jamal, Arham, Richards, Nick, Price, Helen, Rowbotham, Bridie, Bird, Danielle, Smith, Karen, Littler, Olga, Fielding, Kirsty, Townsend-Rose, Anna, Miller, Karen, Davis, Jessica, Elliot-Garwood, Alison, Trottier, Lauren, Edwards, Paul, McFarland, Margaret, Osanlou, Orod, Longshaw, Laura, Stockport, Jane, Grundy, Lynne, Broad, Katharine Lucy, Regan, Karen, Storton, Kim, Ryan-Wakeling, Declan, Wilson, Brad, Munisamy, Malathy, Wright, John, Shenoy, Anil, English, Beverley, Brear, Lucy, Cicconi, Paola, Boffito, Marta, Milinkovic, Ana, Byrne, Ruth, Movahedi, Roya, Housman, Rosalie, Kara, Naveed, Brown, Ellen, Cipriani, Andrea, Attenburrow, Mary-Jane, Smith, Katharine A., Packham, Jonathan, Sparrow, Geoff, Smith, Richard, Rosier, Josephine M., Saja, Khalid, Nago, Nyasha, Camilleri, Brian, Immanuel, Anita, Hamblin, Mike, Osagie, Rawlings, Mohan, Mahalakshmi, Floyd, Hilary, Goddard, Suzanne, Mutgi, Sanjay, Evans, John, McKeon, Sean, Vilimiene, Neringa, Chicano, Rosavic, Hayre, Rachel, Pandaan, Alice, Henshall, Catherine, Serrano, Sonia, Mazzella, Andrea, Rajeswaran, Thurkka, Mathew, Moncy, Bisnauthsing, Karen, Bremner, Laura, Fok, Henry, Morselli, Franca, Cinardo, Paola, Merrick, Blair, Sowole, Lucy, Broadhead, Samantha, Palmer, Natalie, Cordle, Jessica, Goldsmith, Jaimie Wilson, Cooney, Enya, Jackson, Beth, Jayatilleke, Thilina, Cheng, Zelda, Helliwell, Toby, Chudyk, Adrian, Giemza, Rafaela, Villajin, John Lord, Yogo, Noah, Makanju, Esther, Dulawan, Pearl, Nagra, Deepak, Buazon, April, Russell, Alice, Bird, Georgie, Heer, Amardeep, Sarmiento, Rex, Sanghera, Balraj, Mullin, Melanie, Champion, Adam, Bevan, Aisling, Iqbal, Kinzah, Johnson, Alshia, Clark, Rebecca, Shaw, Sarah, Shaw, Steven, Chalk, Amanda, Lovatt, Martin, Lillicrap, Caroline, Parker, Angela, Hansel, Jan, Wong, Zhi, Gan, Galvin, Tuma, Eyad, Minton, Jane, Murira, Jennifer, Saman, Razan, Hall, Alistair, Holliday, Kyra, Khan, Zara, Calderwood, James, Twigg, George, Baker, Helena, Corrigan, Julie, Houseman, Katy, Raguvanshi, Subhra, Heining, Dominic, Weddell, Jake, Glaves, Liz, Thompson, Kim, Davies, Francis, Lambley Burke, Ruth, Thomson, Emma C., Saralaya, Dinesh, Berry, Lisa, Hopewell, Nancy, Gerdes, Leigh, Pacurar, Mihaela, Faust, Saul N., Turner, Jeremy, Jeanes, Christopher, Cooper, Adele, Keshet-Price, Jocelyn, Coke, Lou, Cambell-Kelly, Melissa, Dhatariya, Ketan, Williams, Claire, Marks, Georgina, Sudbury, James, Rodolico, Lisa, Bradley, Judy, Carr, Sharon, Martin, Roisin, Madden, Angelina, Biagioni, Paul, McKenna, Sonia, Clinton, Alison, O'Kane, Maurice, Carter, Justin, Dewhurst, Matthew, Wetherill, Bill, Hoggarth, Thandiwe, Collins, Katrina Lennon, Chowdhury, Marie, Nathoo, Adil, Heinen, Anna, MacDonald, Orla, Hurducas, Claudia, Cifuentes, Liliana, Gill, Harjeevan, Gibson, Andy, West, Raha, Ewing, Jane, Blacow, Rachel, Haughney, John, MacDonald, Jonathan, Seenan, John Paul, Webb, Stewart, O'Leary, Colin, Muir, Scott, White, Beth, Ritchie, Neil, McAuley, Daniel F., Stewart, Jonathan, D'Alessandro, Mariella, Lakeman, Nicki, Purandare, Laura, Browne, Duncan, Tucker, David, Luck, Peter, Everden, Angharad, Trembath, Lisa, Visick, Michael, Morley, Nick, Reid, Laura, Chenoweth, Helen, Maclean, Kirsty, Sheridan, Ray P., Burden, Tom, Lunt, Craig Francis, Todd, Shirley, Estcourt, Stephanie, Pearce, Jasmine Marie, Wilkins, Suzanne, Love-Rouse, Cathryn, Torok-Pollok, Eva, Youle, Mike, Madge, Sara, Solomon, Danielle, Nandani, Aarti, North, Janet M., Hemat, Nargis, Newport, Rachel, Kalra, Philip A., Chukwu, Chukwuma, Wickens, Olivia, O'Loughlin, Vikki, Mistry, Hema, Harrison, Louise, Oliver, Robert, Peers, Anne-Marie, Zadik, Jess, Doyle, Katie, Chadwick, David R., Colling, Kerry, Wroe, Caroline, Branch, Marie, Chilvers, Alison, Essex, Sarah, Stone, Mark, San Francisco Ramos, Alberto, Beales, Emily, Bird, Olivia, Danos, Zsofia, Fofie, Hazel, Hultin, Cecilia, Ikram, Sabina, Mabesa, Fran, Mescall, Aoife, Pereira, Josyanne, Pearce, Jennifer, Sutton, Natalina, Snashall, Emma, Baxter, David Neil, Bennett, Sara, Suggitt, Debbie, Hughes, Kerry, Woodyatt, Wiesia, Beacon, Lynsey, Kent, Alissa, Cooper, Chris, Rudic, Milan, Tunstall, Simon, Jackson, Matthew, Hombersley, Claire, Moore, Patrick, Cutts, Rebecca, Higham, Andrew, Bukhari, Marwan, Elnaggar, Mohamed, Glover, Michelle, Richardson, Fiona, Dent, Alexandra, Mirza, Shahzeb, Ark, Rajiv, Han, Jennie, Hope, Suzy V., Mitchelmore, Philip J., Osanlou, Rostam, Freedman, Andrew, Cooper, Alison, Burton, Katherine, Katechia, Kashyap, Barrett, Michael, Salkeld, Jo, Hill, Natalie, Lee, Nathaniel, Perkins, Jon, Fox, Polly, Toback, Seth, Galiza, Eva, Cosgrove, Catherine, Galloway, James, Goodman, Anna L, Swift, Pauline A, Rajaram, Sankarasubramanian, Graves-Jones, Alison, Edelman, Jonathan, Burns, Fiona, Minassian, Angela M, Cho, Iksung, Kumar, Lakshmi, Plested, Joyce S, Rivers, E Joy, Robertson, Andreana, Dubovsky, Filip, Glenn, Greg, and Heath, Paul T

Published
2022
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3. Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Ahlström Emanuelsson, Cecilia, Ardusso, Ledit, Armstrong, Michael, Bardin, Philip, Barnes, Sara, Bergna, Miguel, Betz, Christian, Beule, Achim, Blotter, James, Bronescu, Valeriu, Brown, Matthew, Carrie, Sean, Chaker, Adam, Cho, Hyung-Ju, Corriveau, Marie-Noëlle, Courville, Timothy, Cuevas, Mandy, Damask, Cecelia, DeConde, Adam, Del Carpio, Jaime, De Salvo, María, Dhong, Hun-Jong, Durham, Stephen, Edin, Anton, Ehmer Jr, Dale, Elías, Pedro, Fatakia, Adil, Franzese, Christine, Gane, Simon, García, Gabriel, Gillman, Andrew, Groeger, Moritz, Harvey, Richard, Hellgren, Johan, Higgins, Thomas, Hobson, Jonathan, Jangard, Mattias, Janjua, Arif, Kara, Naveed, Karpischenko, Sergey, Kerwin, Edward, Khanova, Fatimat, Kilty, Shaun, Kim, Chang-Hoon, Kim, Seontae, Klimek, Ludger, LaForce, Craig, Leong, Samuel, Marple, Bradley, Mårtensson, Anders, Maspero, Jorge, Massey, Neil, Matz, Jonathan, McDuffie, Chad, Mella, Corina, Miller, Steven, Mirzabekyan, Ekaterina, Moss, Jonathan, Mumneh, Nayla, Nathan, Robert, Neagos, Adriana, Olze, Heidi, Ovchinnikov, Andrey, Ow, Randall, Polyakov, Dmitriy, Radeanu, Doinel, Rhee, Chae-Seo, Rojas, Ramón, Rosenbloom, Jeffrey, Ryazantsev, Sergei, Sader, Chady, Saez Scherbovsky, Pablo, Scadding, Guy, Schlosser, Rodney, Shah-Patel, Heena, Shealy, Ronald, Siddiqi, Ayesha, Silvers, Stacey, Singh, Narinder, Sommer, Doron, Soong, Weily, Sowerby, Leigh, Spafford, Peter, Stefan, Catalin, Sterling, Richard, Svistushkin, Valeriy, Talreja, Neetu, Tarasova, Galina, Tarpay, Martha, Tolcachier, Alberto, Toll, Karin Toll, van Schaik, Carolina, Webb, Luke, Wedner, H James, Wehbe, Luis, Whan Kim, Soo, Wollenberg, Barbara, Wright, Simon, Yakusevich, Vladimir, Yañez, Anahí, Yarin, Yury, Yen, David, Yeol Kim, Hyo, Han, Joseph K, Bachert, Claus, Fokkens, Wytske, Desrosiers, Martin, Wagenmann, Martin, Lee, Stella E, Smith, Steven G, Martin, Neil, Mayer, Bhabita, Yancey, Steven W, Sousa, Ana R, Chan, Robert, and Hopkins, Claire

Published
2021
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4. Clinical effectiveness of septoplasty versus medical management for nasal airways obstruction: multicentre, open label, randomised controlled trial

Author

Carrie, Sean, primary, O’Hara, James, additional, Fouweather, Tony, additional, Homer, Tara, additional, Rousseau, Nikki, additional, Rooshenas, Leila, additional, Bray, Alison, additional, Stocken, Deborah D, additional, Ternent, Laura, additional, Rennie, Katherine, additional, Clark, Emma, additional, Waugh, Nichola, additional, Steel, Alison J, additional, Dooley, Jemima, additional, Drinnan, Michael, additional, Hamilton, David, additional, Lloyd, Kelly, additional, Oluboyede, Yemi, additional, Wilson, Caroline, additional, Gardiner, Quentin, additional, Kara, Naveed, additional, Khwaja, Sadie, additional, Leong, Samuel C, additional, Maini, Sangeeta, additional, Morrison, Jillian, additional, Nix, Paul, additional, Wilson, Janet A, additional, and Teare, M Dawn, additional

Published
2023
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5. Prevalence of asthma, aspirin sensitivity and allergy in chronic rhinosinusitis: data from the UK National Chronic Rhinosinusitis Epidemiology Study

Author

Philpott, Carl M., Erskine, Sally, Hopkins, Claire, Kumar, Nirmal, Anari, Shahram, Kara, Naveed, Sunkaraneni, Sankalp, Ray, Jaydip, Clark, Allan, Wilson, Andrew, On behalf of the CRES group, Erskine, Sally, Philpott, Carl, Clark, Allan, Hopkins, Claire, Robertson, Alasdair, Ahmed, Shahzada, Kara, Naveed, Carrie, Sean, Sunkaraneni, Vishnu, Ray, Jaydip, Anari, Shahram, Jervis, Paul, Panesaar, Jaan, Farboud, Amir, Kumar, Nirmal, Cathcart, Russell, Almeyda, Robert, Khalil, Hisham, Prinsley, Peter, Mansell, Nicolas, Salam, Mahmoud, Hobson, Jonathan, Woods, Jane, and Coombes, Emma

Published
2018
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6. Admission avoidance in acute epistaxis: A prospective national audit during the initial peak of the COVID‐19 pandemic

Author

Smith, Matthew E., Swords, Chloe, Rocke, John P. J., Walker, Abigail, Bryan, James E., Milinis, Kristijonas, Mathew, Rajeev G., Jones, Gareth H., McLaren, Oliver, Hutson, Kristian, Slovick, Anna, Hopkins, Claire, Harries, Philip G., Heward, Elliot, Shakeel, Muhammad, Gomati, Anas, Bance, Manohar, Lancaster, Jeffrey, Gaskell, Peter, Smyth, Catherine, Dorris, Colm, Kelly, Andrew, McCrory, David, Bhatt, Yogesh M., Jama, Guled M., Morgan, Montio, Perkins, Victoria, Spraggs, Paul, Khosla, Shivun, Takwoingi, Yohanna, Gopala‐Krishnan, Srinish, Strachan, David, Omakobia, Eugene, Puvanendran, Mark, Myuran, Tharsika, Rennie, Catherine, Devabalan, Yadsan, Cardozo, Arun, Tse, Antonia, McRae, Duncan, Burgan, Omar T., Reddy, Ekambar, Wright, Brendan, Kara, Naveed, Ivy, Ashleigh, Williams, Richard, Walkden, Alex, Quraishi, Muhammad, Stobbs, Nicola, Chatzimichalis, Michail, Elston, Emily, Khemani, Sameer, Liu, Alison, Kirkland, Paul, Vasanthan, Rishi, Miah, Mohammed, Lee, Kristina, Mclarnon, Claire, Williams, Mark R, Okonkwo, Okechukwu, Mughal, Zahir, Karagama, Yakubu, Xie, Carol, De, Mriganka, Amlani, Aakash, Jassar, Patrick, Cao, Han, Patil, Sachin, Philpott, Carl, Meghji, Sheneen, Das, Sudip, Cole, Simon, Vijendren, Ananth, Ally, Munira, Kothari, Prasad, Schechter, Eyal, Ranganathan, Baskaran, Advani, Rajeev, Toma, Shamim, Haymes, Adam, Shakir, Adam, Yap, Darren, Costello, Rhodri, Evans, Louise, Chisholm, Edward, Ojha, Shilpa, Spielmann, Patrick, Steven, Richard, Supriya, Mrinal, Mathew, Elizabeth, Masood, Ajmal, Dewhurst, Samuel, Ward, Victoria, Haigh, Thomas, Patiar, Shalini, Nemeth, Zsofia, Terry, Roland, Vithlani, Rohan, Bowyer, Duncan, Yang, Ding, Monksfield, Peter, Muzaffar, Jameel, Siddiq, Azher, Whittaker, Joshua D, Ramakrishnan, Yujay, Vakharia, Nilesh, Cain, Angus, Cooper, Fergus, Izzat, Steve, Nair, Dilip, Tan, Shawn, Daudia, Anu, Gilchrist, Jennifer, Tan, Neil, Kim, Min, Singh, Vijay, Hallett, Emma, Ray, Jaydip, Yu, Beverley, DeCarpentier, John, Chandrasekar, Bhargavi, Bhimrao, Sanjiv, Eastwood, Michael, Sunkaraneni, Vishnu S., Patel, Jamie, Moore, Andrew, Shetty, Prajwal, Mawby, Thomas, Shelton, Fenella, Jindal, Mudit, Yao, Alexander, Geyer, Marcel, Lowe, Emily, Jones, Huw, Ghasemi, Aria Amir, Trinidade, Aaron, Hardy, Alistair, Little, Sarah, Munroe‐Gray, Tiffany, Bennett, Alex, Li, Lucy, Khalid‐Raja, Mamoona, McNally, George, Thomas, George, Elmorsy, Mohamed, Williams, Clare, Zammit, Matthew, Seymour, Kay, Warner, Elinor, Potter, Chris, Easto, Rachel, Shaida, Azhar, Forde, Cillian T., Karamchandani, Dheeraj, Gill, Charn, Syed, Irfan, Walker, David, Stewart, Kirsten, Simmons, Mark, Abou‐Foul, Ahmad K, Bathala, Srinivasalu, Emerson, Hannah, Almeyda, John, Leadon, Madeline, Fahmy, Fahmy, Kaleva, Anna I., Moorthy, Ram, Bates, James, Wasson, Joseph, Selwyn, Anya, Daultrey, Charles, Patel, Sanjay, Siau, Derrick, Sawant, Rupali, Moore, Phillip, and Ali, Faiza

Subjects
Adult, Male, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Referral, Secondary care, 03 medical and health sciences, 0302 clinical medicine, Clinical Protocols, Pandemic, medicine, Humans, Prospective Studies, 030223 otorhinolaryngology, National audit, Medical Audit, Adult patients, business.industry, COVID-19, Emergency department, United Kingdom, Hospitalization, Epistaxis, Otorhinolaryngology, 030220 oncology & carcinogenesis, Acute Disease, Emergency medicine, Ambulatory, Female, Emergency Service, Hospital, business
Abstract

OBJECTIVES: To report changes in practice brought about by COVID-19 and the implementation of new guidelines, and to explore factors relating to unscheduled re-presentations for patients discharged from the emergency department (ED). DESIGN: Prospective multicentre national audit over 12 weeks from 6th April 2020. SETTING: UK secondary care ENT departments. PARTICIPANTS: Adult patients with acute epistaxis. MAIN OUTCOME MEASURES: Re-presentation within 10 days for patients discharged from the ED. RESULTS: Eighty three centres from all four UK nations submitted 2631 valid cases. The majority of cases were ED referrals (89.7%, n = 2358/2631). 54.6% were discharged from the ED following ENT review (n = 1267/2322), of whom 19.5% re-presented within 10 days (n = 245/1259) and 6.8% were ultimately admitted (n = 86/1259). 46.7% of patients had a non-dissolvable pack inserted by ED prior to referral to ENT (n = 1099/2355). The discharge rates for ED patients and their subsequent re-presentation rates were as follows: non-dissolvable packs, 29.5% discharged (n = 332/1125), 18.2% re-presented (n = 60/330); dissolvable products, 71.1% discharged (n = 488/686), 21.8% re-presented (n = 106/486); cautery only, 89.2% discharged (n = 247/277), 20.0% re-presented (n = 49/245); and no intranasal intervention, 85.5% discharged (n = 200/234), 15.2% re-presented (n = 30/198). Univariable logistic regression showed that not being packed by ED, antiplatelet medications, failed cautery and recent epistaxis treatment were significant predictors of re-presentation within 10 days. CONCLUSIONS: Management of acute epistaxis was notably affected during the initial peak of the pandemic, with a shift towards reduced admissions. This national audit highlights that many patients who may previously have been admitted to hospital may be safely discharged from the ED following acute epistaxis.

Published
2021

7. Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial

Author

Toback, Seth, primary, Galiza, Eva, additional, Cosgrove, Catherine, additional, Galloway, James, additional, Goodman, Anna L, additional, Swift, Pauline A, additional, Rajaram, Sankarasubramanian, additional, Graves-Jones, Alison, additional, Edelman, Jonathan, additional, Burns, Fiona, additional, Minassian, Angela M, additional, Cho, Iksung, additional, Kumar, Lakshmi, additional, Plested, Joyce S, additional, Rivers, E Joy, additional, Robertson, Andreana, additional, Dubovsky, Filip, additional, Glenn, Greg, additional, Heath, Paul T, additional, Soiza, Roy L., additional, Brittain-Long, Robin, additional, Scicluna, Chiara, additional, Edwards, Carole, additional, Mackay, Lynn, additional, D'Allesandro, Mariella, additional, Nicol, Amy, additional, Norris, Karen, additional, Mann, Sandra, additional, Lawrence, Heather, additional, Valentine, Ruth, additional, Viljoen, Marianne Elizabeth, additional, Pretswell, Carol H., additional, Nicholls, Helen, additional, Munsoor, Imrozia, additional, Meyrick, Agnieszka, additional, Kyriakidou, Christina, additional, Iyengar, Shalini, additional, Jamal, Arham, additional, Richards, Nick, additional, Price, Helen, additional, Rowbotham, Bridie, additional, Bird, Danielle, additional, Smith, Karen, additional, Littler, Olga, additional, Fielding, Kirsty, additional, Townsend-Rose, Anna, additional, Miller, Karen, additional, Davis, Jessica, additional, Elliot-Garwood, Alison, additional, Trottier, Lauren, additional, Edwards, Paul, additional, McFarland, Margaret, additional, Osanlou, Orod, additional, Longshaw, Laura, additional, Stockport, Jane, additional, Grundy, Lynne, additional, Broad, Katharine Lucy, additional, Regan, Karen, additional, Storton, Kim, additional, Ryan-Wakeling, Declan, additional, Wilson, Brad, additional, Munisamy, Malathy, additional, Wright, John, additional, Shenoy, Anil, additional, English, Beverley, additional, Brear, Lucy, additional, Cicconi, Paola, additional, Boffito, Marta, additional, Milinkovic, Ana, additional, Byrne, Ruth, additional, Movahedi, Roya, additional, Housman, Rosalie, additional, Kara, Naveed, additional, Brown, Ellen, additional, Cipriani, Andrea, additional, Attenburrow, Mary-Jane, additional, Smith, Katharine A., additional, Packham, Jonathan, additional, Sparrow, Geoff, additional, Smith, Richard, additional, Rosier, Josephine M., additional, Saja, Khalid, additional, Nago, Nyasha, additional, Camilleri, Brian, additional, Immanuel, Anita, additional, Hamblin, Mike, additional, Osagie, Rawlings, additional, Mohan, Mahalakshmi, additional, Floyd, Hilary, additional, Goddard, Suzanne, additional, Mutgi, Sanjay, additional, Evans, John, additional, McKeon, Sean, additional, Vilimiene, Neringa, additional, Chicano, Rosavic, additional, Hayre, Rachel, additional, Pandaan, Alice, additional, Henshall, Catherine, additional, Serrano, Sonia, additional, Mazzella, Andrea, additional, Rajeswaran, Thurkka, additional, Mathew, Moncy, additional, Bisnauthsing, Karen, additional, Bremner, Laura, additional, Fok, Henry, additional, Morselli, Franca, additional, Cinardo, Paola, additional, Merrick, Blair, additional, Sowole, Lucy, additional, Broadhead, Samantha, additional, Palmer, Natalie, additional, Cordle, Jessica, additional, Goldsmith, Jaimie Wilson, additional, Cooney, Enya, additional, Jackson, Beth, additional, Jayatilleke, Thilina, additional, Cheng, Zelda, additional, Helliwell, Toby, additional, Chudyk, Adrian, additional, Giemza, Rafaela, additional, Villajin, John Lord, additional, Yogo, Noah, additional, Makanju, Esther, additional, Dulawan, Pearl, additional, Nagra, Deepak, additional, Buazon, April, additional, Russell, Alice, additional, Bird, Georgie, additional, Heer, Amardeep, additional, Sarmiento, Rex, additional, Sanghera, Balraj, additional, Mullin, Melanie, additional, Champion, Adam, additional, Bevan, Aisling, additional, Iqbal, Kinzah, additional, Johnson, Alshia, additional, Clark, Rebecca, additional, Shaw, Sarah, additional, Shaw, Steven, additional, Chalk, Amanda, additional, Lovatt, Martin, additional, Lillicrap, Caroline, additional, Parker, Angela, additional, Hansel, Jan, additional, Wong, Zhi, additional, Gan, Galvin, additional, Tuma, Eyad, additional, Minton, Jane, additional, Murira, Jennifer, additional, Saman, Razan, additional, Hall, Alistair, additional, Holliday, Kyra, additional, Khan, Zara, additional, Calderwood, James, additional, Twigg, George, additional, Baker, Helena, additional, Corrigan, Julie, additional, Houseman, Katy, additional, Raguvanshi, Subhra, additional, Heining, Dominic, additional, Weddell, Jake, additional, Glaves, Liz, additional, Thompson, Kim, additional, Davies, Francis, additional, Lambley Burke, Ruth, additional, Thomson, Emma C., additional, Saralaya, Dinesh, additional, Berry, Lisa, additional, Hopewell, Nancy, additional, Gerdes, Leigh, additional, Pacurar, Mihaela, additional, Faust, Saul N., additional, Turner, Jeremy, additional, Jeanes, Christopher, additional, Cooper, Adele, additional, Keshet-Price, Jocelyn, additional, Coke, Lou, additional, Cambell-Kelly, Melissa, additional, Dhatariya, Ketan, additional, Williams, Claire, additional, Marks, Georgina, additional, Sudbury, James, additional, Rodolico, Lisa, additional, Bradley, Judy, additional, Carr, Sharon, additional, Martin, Roisin, additional, Madden, Angelina, additional, Biagioni, Paul, additional, McKenna, Sonia, additional, Clinton, Alison, additional, O'Kane, Maurice, additional, Carter, Justin, additional, Dewhurst, Matthew, additional, Wetherill, Bill, additional, Hoggarth, Thandiwe, additional, Collins, Katrina Lennon, additional, Chowdhury, Marie, additional, Nathoo, Adil, additional, Heinen, Anna, additional, MacDonald, Orla, additional, Hurducas, Claudia, additional, Cifuentes, Liliana, additional, Gill, Harjeevan, additional, Gibson, Andy, additional, West, Raha, additional, Ewing, Jane, additional, Blacow, Rachel, additional, Haughney, John, additional, MacDonald, Jonathan, additional, Seenan, John Paul, additional, Webb, Stewart, additional, O'Leary, Colin, additional, Muir, Scott, additional, White, Beth, additional, Ritchie, Neil, additional, McAuley, Daniel F., additional, Stewart, Jonathan, additional, D'Alessandro, Mariella, additional, Lakeman, Nicki, additional, Purandare, Laura, additional, Browne, Duncan, additional, Tucker, David, additional, Luck, Peter, additional, Everden, Angharad, additional, Trembath, Lisa, additional, Visick, Michael, additional, Morley, Nick, additional, Reid, Laura, additional, Chenoweth, Helen, additional, Maclean, Kirsty, additional, Sheridan, Ray P., additional, Burden, Tom, additional, Lunt, Craig Francis, additional, Todd, Shirley, additional, Estcourt, Stephanie, additional, Pearce, Jasmine Marie, additional, Wilkins, Suzanne, additional, Love-Rouse, Cathryn, additional, Torok-Pollok, Eva, additional, Youle, Mike, additional, Madge, Sara, additional, Solomon, Danielle, additional, Nandani, Aarti, additional, North, Janet M., additional, Hemat, Nargis, additional, Newport, Rachel, additional, Kalra, Philip A., additional, Chukwu, Chukwuma, additional, Wickens, Olivia, additional, O'Loughlin, Vikki, additional, Mistry, Hema, additional, Harrison, Louise, additional, Oliver, Robert, additional, Peers, Anne-Marie, additional, Zadik, Jess, additional, Doyle, Katie, additional, Chadwick, David R., additional, Colling, Kerry, additional, Wroe, Caroline, additional, Branch, Marie, additional, Chilvers, Alison, additional, Essex, Sarah, additional, Stone, Mark, additional, San Francisco Ramos, Alberto, additional, Beales, Emily, additional, Bird, Olivia, additional, Danos, Zsofia, additional, Fofie, Hazel, additional, Hultin, Cecilia, additional, Ikram, Sabina, additional, Mabesa, Fran, additional, Mescall, Aoife, additional, Pereira, Josyanne, additional, Pearce, Jennifer, additional, Sutton, Natalina, additional, Snashall, Emma, additional, Baxter, David Neil, additional, Bennett, Sara, additional, Suggitt, Debbie, additional, Hughes, Kerry, additional, Woodyatt, Wiesia, additional, Beacon, Lynsey, additional, Kent, Alissa, additional, Cooper, Chris, additional, Rudic, Milan, additional, Tunstall, Simon, additional, Jackson, Matthew, additional, Hombersley, Claire, additional, Moore, Patrick, additional, Cutts, Rebecca, additional, Higham, Andrew, additional, Bukhari, Marwan, additional, Elnaggar, Mohamed, additional, Glover, Michelle, additional, Richardson, Fiona, additional, Dent, Alexandra, additional, Mirza, Shahzeb, additional, Ark, Rajiv, additional, Han, Jennie, additional, Hope, Suzy V., additional, Mitchelmore, Philip J., additional, Osanlou, Rostam, additional, Freedman, Andrew, additional, Cooper, Alison, additional, Burton, Katherine, additional, Katechia, Kashyap, additional, Barrett, Michael, additional, Salkeld, Jo, additional, Hill, Natalie, additional, Lee, Nathaniel, additional, Perkins, Jon, additional, and Fox, Polly, additional

Published
2022
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8. SNOT‐22 in a control population

Author

Erskine, S.E., Hopkins, C., Clark, A., Anari, S., Kumar, N., Robertson, A., Sunkaraneni, S., Wilson, J.A., Carrie, S., Kara, N., Ray, J., Smith, R., Philpott, C.M., Philpott, Carl, Erskine, Sally, Clark, Allan, Morris, Steve, Hopkins, Claire, Robertson, Alasdair, Ahmed, Shahzada, Kara, Naveed, Carrie, Sean, Sunkaraneni, Vishnu, Ray, Jaydip, Anari, Shahram, Jervis, Paul, Panesaar, Jaan, Farboud, Amir, Kumar, Nirmal, Cathcart, Russell, Almeyda, Robert, Khalil, Hisham, Prinsley, Peter, Mansell, Nicolas, Salam, Mahmoud, Hobson, Jonathan, Woods, Jane, and Coombes, Emma

Published
2017
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9. Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial

Author

Han, Joseph K, primary, Bachert, Claus, additional, Fokkens, Wytske, additional, Desrosiers, Martin, additional, Wagenmann, Martin, additional, Lee, Stella E, additional, Smith, Steven G, additional, Martin, Neil, additional, Mayer, Bhabita, additional, Yancey, Steven W, additional, Sousa, Ana R, additional, Chan, Robert, additional, Hopkins, Claire, additional, Ahlström Emanuelsson, Cecilia, additional, Ardusso, Ledit, additional, Armstrong, Michael, additional, Bardin, Philip, additional, Barnes, Sara, additional, Bergna, Miguel, additional, Betz, Christian, additional, Beule, Achim, additional, Blotter, James, additional, Bronescu, Valeriu, additional, Brown, Matthew, additional, Carrie, Sean, additional, Chaker, Adam, additional, Cho, Hyung-Ju, additional, Corriveau, Marie-Noëlle, additional, Courville, Timothy, additional, Cuevas, Mandy, additional, Damask, Cecelia, additional, DeConde, Adam, additional, Del Carpio, Jaime, additional, De Salvo, María, additional, Dhong, Hun-Jong, additional, Durham, Stephen, additional, Edin, Anton, additional, Ehmer Jr, Dale, additional, Elías, Pedro, additional, Fatakia, Adil, additional, Franzese, Christine, additional, Gane, Simon, additional, García, Gabriel, additional, Gillman, Andrew, additional, Groeger, Moritz, additional, Harvey, Richard, additional, Hellgren, Johan, additional, Higgins, Thomas, additional, Hobson, Jonathan, additional, Jangard, Mattias, additional, Janjua, Arif, additional, Kara, Naveed, additional, Karpischenko, Sergey, additional, Kerwin, Edward, additional, Khanova, Fatimat, additional, Kilty, Shaun, additional, Kim, Chang-Hoon, additional, Kim, Seontae, additional, Klimek, Ludger, additional, LaForce, Craig, additional, Leong, Samuel, additional, Marple, Bradley, additional, Mårtensson, Anders, additional, Maspero, Jorge, additional, Massey, Neil, additional, Matz, Jonathan, additional, McDuffie, Chad, additional, Mella, Corina, additional, Miller, Steven, additional, Mirzabekyan, Ekaterina, additional, Moss, Jonathan, additional, Mumneh, Nayla, additional, Nathan, Robert, additional, Neagos, Adriana, additional, Olze, Heidi, additional, Ovchinnikov, Andrey, additional, Ow, Randall, additional, Polyakov, Dmitriy, additional, Radeanu, Doinel, additional, Rhee, Chae-Seo, additional, Rojas, Ramón, additional, Rosenbloom, Jeffrey, additional, Ryazantsev, Sergei, additional, Sader, Chady, additional, Saez Scherbovsky, Pablo, additional, Scadding, Guy, additional, Schlosser, Rodney, additional, Shah-Patel, Heena, additional, Shealy, Ronald, additional, Siddiqi, Ayesha, additional, Silvers, Stacey, additional, Singh, Narinder, additional, Sommer, Doron, additional, Soong, Weily, additional, Sowerby, Leigh, additional, Spafford, Peter, additional, Stefan, Catalin, additional, Sterling, Richard, additional, Svistushkin, Valeriy, additional, Talreja, Neetu, additional, Tarasova, Galina, additional, Tarpay, Martha, additional, Tolcachier, Alberto, additional, Toll, Karin Toll, additional, van Schaik, Carolina, additional, Webb, Luke, additional, Wedner, H James, additional, Wehbe, Luis, additional, Whan Kim, Soo, additional, Wollenberg, Barbara, additional, Wright, Simon, additional, Yakusevich, Vladimir, additional, Yañez, Anahí, additional, Yarin, Yury, additional, Yen, David, additional, and Yeol Kim, Hyo, additional

Published
2021
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10. Admission avoidance in tonsillitis and peritonsillar abscess: A prospective national audit during the initial peak of the COVID‐19 pandemic

Author

Hardman, John C, Swords, Chloe, Rocke, John P J, Walker, Abigail, Bryan, James E, Milinis, Kristijonas, Mathew, Rajeev G, Jones, Gareth H, McLaren, Oliver, Smith, Matthew E, Hutson, Kristian, Slovick, Anna, McNally, George, Burgess, Andrea, Shakeel, Muhammad, Gomati, Anas, Bance, Manohar, Lancaster, Jeffrey, Maple, Natalie, Smyth, Catherine, Dorris, Colm, Kelly, Andrew, McCrory, David, MBhatt, Yogesh, Jama, Guled M, Morgan, Montio, Perkins, Victoria, Spraggs, Paul, Geyton, Thomas, Takwoingi, Yohanna, Gopala‐Krishnan, Srinish, Strachan, David, Taylor, Robert, Puvanendran, Mark, Egan, Matthew, Rennie, Catherine, Cereceda‐Monteoliva, Nicholas, Cardozo, Arun, Tse, Antonia, McRae, Duncan, Burgan, Omar T, Reddy, Ekambar, Wright, Brendan, Kara, Naveed, Walters, Holt, Williams, Richard, Walkden, Alex, Quraishi, Muhammad, Stobbs, Nicola, Chatzimichalis, Michail, Elston, Emily, Khemani, Sameer, Fang, Sean, Kirkland, Paul, Vasanthan, Rishi, Miah, Mohammed, Lee, Kristina, Mclarnon, Claire, Williams, Mark R, Okonkwo, Okechukwu, Mughal, Zahir, Karagama, Yakubu, Xie, Carol, De, Mriganka, Amlani, Aakash, Jassar, Patrick, Cao, Han, Patil, Sachin, Wong, Billy, Philpott, Carl, Meghji, Sheneen, Das, Sudip, Cole, Simon, Vijendren, Ananth, Ally, Munira, Kothari, Prasad, Schechter, Eyal, Ranganathan, Baskaran, Advani, Rajeev, Toma, Shamim, Haymes, Adam, Shakir, Adam, Yap, Darren, Costello, Rhodri, Wallace, Jennifer, Chisholm, Edward, Ojha, Shilpa, Spielmann, Patrick, Steven, Richard, Supriya, Mrinal, Mathew, Elizabeth, Masood, Ajmal, Dewhurst, Samuel, Ward, Victoria, Darwich, Ayman, Patiar, Shalini, Nemeth, Zsofia, Terry, Roland, Vithlani, Rohan, Bowyer, Duncan, Yang, Ding, Monksfield, Peter, Corbett, Peter, Siddiq, Azher, Whittaker, Joshua D, Ramakrishnan, Yujay, Cho, Wai Sum, Cain, Angus, Mondal, Bobby, Izzat, Steve, Ainine, Amru, Nair, Dilip, Tan, Shawn, Daudia, Anu, Gilchrist, Jennifer, Tan, Neil, Kim, Min, Truro, Singh, Vijay, Hallett, Emma, Ray, Jaydip, Yu, Beverley, DeCarpentier, John, Chandrasekar, Bhargavi, Bhimrao, Sanjiv, Eastwood, Michael, Sunkaraneni, Vishnu S, Lee, Chang Woo, Moore, Andrew, Shetty, Prajwal, Mawby, Thomas, Bisson, Elspeth, Jindal, Mudit, Yao, Alexander, Geyer, Marcel, Mohammed, Omnya, Jones, Huw, Ghasemi, Aria Amir, Trinidade, Aaron, Hardy, Alistair, Little, Sarah, Munroe‐Gray, Tiffany, Bennett, Alex, Li, Lucy, Khalid‐Raja, Mamoona, Thomas, George, Elmorsy, Mohamed, Williams, Clare, Zammit, Matthew, Seymour, Kay, Warner, Elinor, Potter, Chris, Easto, Rachel, Shaida, Azhar, Elshahhat, Mohamed, Karamchandani, Dheeraj, Gill, Charn, Syed, Irfan, Walker, David, Stewart, Kirsten, Simmons, Mark, Abou‐Foul, Ahmad K, Bathala, Srinivasalu, Emerson, Hannah, Almeyda, John, Pericleous, Agamemnon, Fahmy, Fahmy, Kaleva, AnnaI, Moorthy, Ram, Bates, James, Wasson, Joseph, Selwyn, Anya, Daultrey, Charles, Patel, Sanjay, Siau, Derrick, Sawant, Rupali, Moore, Phillip, and Rajamanickan, Senthil Kumar

Subjects
Male, Time Factors, multicentre, Tonsillitis, ambulatory, Comorbidity, Patient Admission, 0302 clinical medicine, Pandemic, Ambulatory Care, Medicine, Prospective Studies, Practice Patterns, Physicians', 030223 otorhinolaryngology, Aged, 80 and over, Acute Tonsillitis, Disease Management, Outpatient, Middle Aged, 030220 oncology & carcinogenesis, Ambulatory, Female, Original Article, Adult, medicine.medical_specialty, Adolescent, Coronavirus disease 2019 (COVID-19), Young Adult, 03 medical and health sciences, Ambulatory care, stomatognathic system, discharge, Internal medicine, otorhinolaryngologic diseases, Humans, observational, Peritonsillar Abscess, Pandemics, Aged, Retrospective Studies, Clinical Audit, SARS-CoV-2, business.industry, COVID-19, Original Articles, Emergency department, medicine.disease, United Kingdom, Otorhinolaryngology, business, Follow-Up Studies
Abstract

Objectives To report changes in practice brought about by COVID‐19 and the implementation of new guidelines for the management of tonsillitis and peritonsillar abscess (PTA), and to explore factors relating to unscheduled re‐presentations for patients discharged from the emergency department (ED). Design Prospective multicentre national audit over 12 weeks from 6 April 2020. Setting UK secondary care ENT departments. Participants Adult patients with acute tonsillitis or PTA. Main outcome measures Re‐presentation within 10 days for patients discharged from the ED. Results 83 centres submitted 765 tonsillitis and 416 PTA cases. 54.4% (n = 410) of tonsillitis and 45.3% (187/413) of PTAs were discharged from ED. 9.6% (39/408) of tonsillitis and 10.3% (19/184) of PTA discharges re‐presented within 10 days, compared to 9.7% (33/341) and 10.6% (24/224) for those admitted from ED. The subsequent admission rate of those initially discharged from ED was 4.7% for tonsillitis and 3.3% for PTAs. IV steroids and antibiotics increased the percentage of patients able to swallow from 35.8% to 72.5% for tonsillitis (n = 270/754 and 441/608) and from 22.3% to 71.0% for PTA (n = 92/413 and 265/373). 77.2% of PTAs underwent drainage (n = 319/413), with no significant difference in re‐presentations in those drained vs not‐drained (10.6% vs 9.5%, n = 15/142 vs 4/42, P = .846). Univariable logistic regression showed no significant predictors of re‐presentation within 10 days. Conclusions Management of tonsillitis and PTA changed during the initial peak of the pandemic, shifting towards outpatient care. Some patients who may previously have been admitted to hospital may be safely discharged from the ED.

Published
2021

11. British Rhinological Society Consensus Guidance on the use of biological therapies for chronic rhinosinusitis with nasal polyps

Author

Hopkins, Claire, primary, McKenzie, Jo‐Lyn, additional, Anari, Shahram, additional, Carrie, Sean, additional, Ramakrishnan, Yujay, additional, Kara, Naveed, additional, Philpott, Carl, additional, Hobson, Jonathan, additional, Qureishi, Ali, additional, Stew, Ben, additional, Bhalla, Raj, additional, Gane, Simon, additional, Walker, Abigail, additional, Harries, Phil, additional, Hathorn, Iain, additional, and Lund, Valerie, additional

Published
2021
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12. Socioeconomic, comorbidity, lifestyle and quality of life comparisons between chronic rhinosinusitis phenotypes: Data from the National Chronic Rhinosinusitis Epidemiology Study

Author

Philpott, Carl, primary, Ta, Tanya, additional, Hopkins, Clair, additional, Ray, Jaydip, additional, Ahmed, Shahzada, additional, Almeyda, Robert, additional, Kara, Naveed, additional, Carrie, Sean, additional, Erskine, S E, additional, Cathcart, Russell, additional, Sunkaraneni, Vishnu, additional, Robertson, Alasdair, additional, Anari, Shahram, additional, Kumar, B, additional, and Clark, Allan, additional

Published
2020
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16. Socioeconomic, comorbidity, lifestyle, and quality of life comparisons between chronic rhinosinusitis phenotypes.

Author

Philpott, Carl, Ta, Ngan Hong, Hopkins, Claire, Ray, Jaydip, Ahmed, Shazhada, Almeyda, Robert, Kara, Naveed, Carrie, Sean, Erskine, Sally E., Cathcart, Russell, Sunkaraneni, Vishnu, Robertson, Alasdair, Anari, Shahram, Kumar, Balasubrahmanyam Nirmal, and Clark, Allan

Abstract

Background: Chronic rhinosinusitis (CRS) is a heterogeneous group of inflammatory sinonasal disorders with key defining symptoms, but traditionally separated into phenotypes by clinical/endoscopic findings. It is not known whether the two phenotypes have differing socioeconomic, comorbidity, and lifestyle differences. This analysis of the Chronic Rhinosinusitis Epidemiology Study (CRES) database sought to analyze any key differences in the socioeconomic variables between those with CRS with nasal polyps (CRSwNPs) and those without nasal polyps (CRSsNPs). We also sought to analyze differences in comorbidities, lifestyle, and quality of life. Methods: Patients with a confirmed diagnosis of CRS in secondary and tertiary care outpatient settings in the UK were invited to participate in a questionnaire‐based case–control study. Variables included demographics, socioeconomic factors, comorbidities, lifestyle factors, and health‐related quality of life (HRQoL) (level 3 evidence). Results: A total of 1204 patients' data were analyzed: 553 CRSsNP and 651 CRSwNP participants. The key socioeconomic variables did not demonstrate any notable differences, nor did lifestyle variables other than alcohol consumption being higher in those with CRSwNP (P =.032), but the latter was not significant after adjusting for age and sex. Aside from confirmation of asthma being more common in CRSwNP, it was notable that this group complained less of upper respiratory tract infections (URTIs), and CRSsNP participants showed evidence of worse HRQoL scores in respect of body pain (P =.001). Conclusions: Patients with CRSwNP experience higher rates of asthma and lower rates of URTIs; patients with CRSsNP have worse body pain scores. Otherwise, there are no demonstrable significant socioeconomic, comorbidity, lifestyle, or quality of life differences between the two phenotypes. Level of Evidence: 3 Laryngoscope, 131:2179–2186, 2021 [ABSTRACT FROM AUTHOR]

Published
2021
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17. Exploring the association between ingestion of foods with higher potential salicylate content and symptom exacerbation in chronic rhinosinusitis. Data from the National Chronic Rhinosinusitis Epidemiology Study.

Author

Philpott, Carl M., Smith, Rupert, Davies-Husband, Cameron R., Erskine, Sally, Clark, Allan, Welch, Ailsa, Hopkins, Claire, Carrie, Sean, Ray, Jaydip, Sunkaraneni, Vishnu, Kara, Naveed, Kumar, Nirmal, Robertson, Alasdair, Anari, Shahram, Almeyda, Robert, and Wilson, Andrew

Published
2019
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26. The burden of revision sinonasal surgery in the UK -- data from the Chronic Rhinosinusitis Epidemiology Study (CRES): a cross-sectional study.

Author

Philpott, Carl, Hopkins, Claire, Erskine, Sally, Kumar, Nirmal, Robertson, Alasdair, Farboud, Amir, Ahmed, Shahzada, Anari, Shahram, Cathcart, Russell, Khalil, Hisham, Jervis, Paul, Carrie, Sean, Kara, Naveed, Prinsley, Peter, Almeyda, Robert, Mansell, Nicolas, Sunkaraneni, Sankalp, Salam, Mahmoud, Ray, Jaydip, and Panesaar, Jaan

Abstract

Objectives: The aim of this study was to investigate the surgical revision rate in patients with chronic rhinosinusitis (CRS) in the UK CRS Epidemiology Study (CRES). Previous evidence from National Sinonasal Audit showed that 1459 patients with CRS demonstrated a surgical revision rate 19.1% at 5 years, with highest rates seen in those with polyps (20.6%). Setting: Thirty secondary care centres around the UK. Participants: A total of 221 controls and 1249 patients with CRS were recruited to the study including those with polyps (CRSwNPs), without polyps (CRSsNPs) and with allergic fungal rhinosinusitis (AFRS). Interventions: Self-administered questionnaire. Primary outcome measure: The need for previous sinonasal surgery. Results: A total of 651 patients with CRSwNPs, 553 with CRSsNPs and 45 with AFRS were included. A total of 396 (57%) patients with CRSwNPs/AFRS reported having undergone previous endoscopic nasal polypectomy (ENP), of which 182 of the 396 (46%) reported having received more than one operation. The mean number of previous surgeries per patient in the revision group was 3.3 (range 2-30) and a mean duration of time of 10 years since the last procedure. The average length of time since their first operation up to inclusion in the study was 15.5 years (range 0-74). Only 27.9% of all patients reporting a prior ENP had received concurrent endoscopic sinus surgery (ESS; n=102). For comparison, surgical rates in patients with CRSsNPs were significantly lower; 13% of cases specifically reported ESS, and of those only 30% reported multiple procedures (χ²p<0.001). Conclusions: This study demonstrated that there is a high burden of both primary and revision surgery in patients with CRS, worst in those with AFRS and least in those with CRSsNPs. The burden of revision surgery appears unchanged in the decade since the Sinonasal Audit. [ABSTRACT FROM AUTHOR]

Published
2015
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28. Polymicrobial Skull Base Osteomyelitis Related to Chronic Sphenoiditis and Endoscopic Sinus Surgery.

Author

Shellman, Zachary, Coates, Matthew, and Kara, Naveed

Abstract

Skull base osteomyelitis (SBO) secondary to endoscopic surgery for chronic sinusitis and post‐operative sphenopalatine artery electrocautery has not been previously reported. This case report details an instance of Central SBO with an unusual microbiology profile and highlights the need to readily consider SBO should patients present with persistent headache and cranial nerve palsies following sinus surgery. Laryngoscope, 131:E1086–E1087, 2021 [ABSTRACT FROM AUTHOR]

Published
2021
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29. Safety, immunogenicity, and efficacy of a COVID-19 vaccine (NVX-CoV2373) co-administered with seasonal influenza vaccines: an exploratory substudy of a randomised, observer-blinded, placebo-controlled, phase 3 trial

Author

Toback, Seth, Galiza, Eva, Cosgrove, Catherine, Galloway, James, Goodman, Anna L, Swift, Pauline A, Rajaram, Sankarasubramanian, Graves-Jones, Alison, Edelman, Jonathan, Burns, Fiona, Minassian, Angela M, Cho, Iksung, Kumar, Lakshmi, Plested, Joyce S, Rivers, E Joy, Robertson, Andreana, Dubovsky, Filip, Glenn, Greg, Heath, Paul T, Soiza, Roy L., Brittain-Long, Robin, Scicluna, Chiara, Edwards, Carole, Mackay, Lynn, D'Allesandro, Mariella, Nicol, Amy, Norris, Karen, Mann, Sandra, Lawrence, Heather, Valentine, Ruth, Viljoen, Marianne Elizabeth, Pretswell, Carol H., Nicholls, Helen, Munsoor, Imrozia, Meyrick, Agnieszka, Kyriakidou, Christina, Iyengar, Shalini, Jamal, Arham, Richards, Nick, Price, Helen, Rowbotham, Bridie, Bird, Danielle, Smith, Karen, Littler, Olga, Fielding, Kirsty, Townsend-Rose, Anna, Miller, Karen, Davis, Jessica, Elliot-Garwood, Alison, Trottier, Lauren, Edwards, Paul, McFarland, Margaret, Osanlou, Orod, Longshaw, Laura, Stockport, Jane, Grundy, Lynne, Broad, Katharine Lucy, Regan, Karen, Storton, Kim, Ryan-Wakeling, Declan, Wilson, Brad, Munisamy, Malathy, Wright, John, Shenoy, Anil, English, Beverley, Brear, Lucy, Cicconi, Paola, Boffito, Marta, Milinkovic, Ana, Byrne, Ruth, Movahedi, Roya, Housman, Rosalie, Kara, Naveed, Brown, Ellen, Cipriani, Andrea, Attenburrow, Mary-Jane, Smith, Katharine A., Packham, Jonathan, Sparrow, Geoff, Smith, Richard, Rosier, Josephine M., Saja, Khalid, Nago, Nyasha, Camilleri, Brian, Immanuel, Anita, Hamblin, Mike, Osagie, Rawlings, Mohan, Mahalakshmi, Floyd, Hilary, Goddard, Suzanne, Mutgi, Sanjay, Evans, John, McKeon, Sean, Vilimiene, Neringa, Chicano, Rosavic, Hayre, Rachel, Pandaan, Alice, Henshall, Catherine, Serrano, Sonia, Mazzella, Andrea, Rajeswaran, Thurkka, Mathew, Moncy, Bisnauthsing, Karen, Bremner, Laura, Fok, Henry, Morselli, Franca, Cinardo, Paola, Merrick, Blair, Sowole, Lucy, Broadhead, Samantha, Palmer, Natalie, Cordle, Jessica, Goldsmith, Jaimie Wilson, Cooney, Enya, Jackson, Beth, Jayatilleke, Thilina, Cheng, Zelda, Helliwell, Toby, Chudyk, Adrian, Giemza, Rafaela, Villajin, John Lord, Yogo, Noah, Makanju, Esther, Dulawan, Pearl, Nagra, Deepak, Buazon, April, Russell, Alice, Bird, Georgie, Heer, Amardeep, Sarmiento, Rex, Sanghera, Balraj, Mullin, Melanie, Champion, Adam, Bevan, Aisling, Iqbal, Kinzah, Johnson, Alshia, Clark, Rebecca, Shaw, Sarah, Shaw, Steven, Chalk, Amanda, Lovatt, Martin, Lillicrap, Caroline, Parker, Angela, Hansel, Jan, Wong, Zhi, Gan, Galvin, Tuma, Eyad, Minton, Jane, Murira, Jennifer, Saman, Razan, Hall, Alistair, Holliday, Kyra, Khan, Zara, Calderwood, James, Twigg, George, Baker, Helena, Corrigan, Julie, Houseman, Katy, Raguvanshi, Subhra, Heining, Dominic, Weddell, Jake, Glaves, Liz, Thompson, Kim, Davies, Francis, Lambley Burke, Ruth, Thomson, Emma C., Saralaya, Dinesh, Berry, Lisa, Hopewell, Nancy, Gerdes, Leigh, Pacurar, Mihaela, Faust, Saul N., Turner, Jeremy, Jeanes, Christopher, Cooper, Adele, Keshet-Price, Jocelyn, Coke, Lou, Cambell-Kelly, Melissa, Dhatariya, Ketan, Williams, Claire, Marks, Georgina, Sudbury, James, Rodolico, Lisa, Bradley, Judy, Carr, Sharon, Martin, Roisin, Madden, Angelina, Biagioni, Paul, McKenna, Sonia, Clinton, Alison, O'Kane, Maurice, Carter, Justin, Dewhurst, Matthew, Wetherill, Bill, Hoggarth, Thandiwe, Collins, Katrina Lennon, Chowdhury, Marie, Nathoo, Adil, Heinen, Anna, MacDonald, Orla, Hurducas, Claudia, Cifuentes, Liliana, Gill, Harjeevan, Gibson, Andy, West, Raha, Ewing, Jane, Blacow, Rachel, Haughney, John, MacDonald, Jonathan, Seenan, John Paul, Webb, Stewart, O'Leary, Colin, Muir, Scott, White, Beth, Ritchie, Neil, McAuley, Daniel F., Stewart, Jonathan, D'Alessandro, Mariella, Lakeman, Nicki, Purandare, Laura, Browne, Duncan, Tucker, David, Luck, Peter, Everden, Angharad, Trembath, Lisa, Visick, Michael, Morley, Nick, Reid, Laura, Chenoweth, Helen, Maclean, Kirsty, Sheridan, Ray P., Burden, Tom, Lunt, Craig Francis, Todd, Shirley, Estcourt, Stephanie, Pearce, Jasmine Marie, Wilkins, Suzanne, Love-Rouse, Cathryn, Torok-Pollok, Eva, Youle, Mike, Madge, Sara, Solomon, Danielle, Nandani, Aarti, North, Janet M., Hemat, Nargis, Newport, Rachel, Kalra, Philip A., Chukwu, Chukwuma, Wickens, Olivia, O'Loughlin, Vikki, Mistry, Hema, Harrison, Louise, Oliver, Robert, Peers, Anne-Marie, Zadik, Jess, Doyle, Katie, Chadwick, David R., Colling, Kerry, Wroe, Caroline, Branch, Marie, Chilvers, Alison, Essex, Sarah, Stone, Mark, San Francisco Ramos, Alberto, Beales, Emily, Bird, Olivia, Danos, Zsofia, Fofie, Hazel, Hultin, Cecilia, Ikram, Sabina, Mabesa, Fran, Mescall, Aoife, Pereira, Josyanne, Pearce, Jennifer, Sutton, Natalina, Snashall, Emma, Baxter, David Neil, Bennett, Sara, Suggitt, Debbie, Hughes, Kerry, Woodyatt, Wiesia, Beacon, Lynsey, Kent, Alissa, Cooper, Chris, Rudic, Milan, Tunstall, Simon, Jackson, Matthew, Hombersley, Claire, Moore, Patrick, Cutts, Rebecca, Higham, Andrew, Bukhari, Marwan, Elnaggar, Mohamed, Glover, Michelle, Richardson, Fiona, Dent, Alexandra, Mirza, Shahzeb, Ark, Rajiv, Han, Jennie, Hope, Suzy V., Mitchelmore, Philip J., Osanlou, Rostam, Freedman, Andrew, Cooper, Alison, Burton, Katherine, Katechia, Kashyap, Barrett, Michael, Salkeld, Jo, Hill, Natalie, Lee, Nathaniel, Perkins, Jon, and Fox, Polly

Abstract

The safety and immunogenicity profile of COVID-19 vaccines when administered concomitantly with seasonal influenza vaccines have not yet been reported. We therefore aimed to report the results of a substudy within a phase 3 UK trial, by evaluating the safety, immunogenicity, and efficacy of NVX-CoV2373 when co-administered with licensed seasonal influenza vaccines.

Published
2021
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30. A case-control study of medical, psychological and socio-economic factors influencing the severity of chronic rhinosinusitis.

Author

Philpott C, Erskine S, Hopkins C, Coombes E, Kara N, Sunkareneni V, Anari S, Salam M, Farboud A, and Clark A

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Chronic Disease, Comorbidity, Educational Status, England epidemiology, Ethnicity statistics & numerical data, Female, Humans, Income statistics & numerical data, Male, Middle Aged, Nasal Polyps epidemiology, Nasal Polyps psychology, Occupations statistics & numerical data, Prospective Studies, Quality of Life psychology, Residence Characteristics statistics & numerical data, Rhinitis epidemiology, Rhinitis psychology, Rhinitis, Allergic epidemiology, Rhinitis, Allergic physiopathology, Rhinitis, Allergic psychology, Rural Population statistics & numerical data, Sinusitis epidemiology, Sinusitis psychology, Socioeconomic Factors, Surveys and Questionnaires, Urban Population statistics & numerical data, Young Adult, Nasal Polyps physiopathology, Rhinitis physiopathology, Severity of Illness Index, Sinusitis physiopathology
Abstract

Background: Chronic rhinosinusitis (CRS) is a common and debilitating disorder. Little is known about the epidemiology of this disease. The aims of the study were to identify differences in socio-economic variables and quality of life between patients with chronic rhinosinusitis and healthy controls, to identify any significant associations between CRS and other medical co-morbidities, psychiatric disease or environmental exposure and to explore the experience of CRS from the perspective of CRS sufferers., Methods: Participants were recruited from ENT clinics from 30 centres across the UK. They completed a study-specific questionnaire considering environmental, medical and socio-economic factors, and SF-36 and SNOT-22 scores. All participants with CRS were diagnosed by a clinician and categorised as having CRS (with polyposis, without polyposis or allergic fungal rhinosinusitis (AFRS)). Controls included family and friends of those attending ENT outpatient clinics and hospital staff who had no diagnosis of nose or sinus problems and had not been admitted to hospital in the previous 12 months., Results: A total of 1470 study participants (1249 patients and 221 controls) were included in the final analysis. Highly significant differences were seen in generic and disease-specific quality of life scores between CRS sufferers and controls; mean SNOT-22 score 45.0 for CRS compared with 12.1 amongst controls. There were no clear differences in socioeconomic variables including social class, index of multiple deprivation and educational attainment between cases and controls. Common comorbidities with a clear association included respiratory and psychiatric disorders, with a higher frequency of reported upper respiratory tract infections., Conclusions: CRS is associated with significant impairment in quality of life and with certain medical co-morbidities. In contrast to other common ENT disorders, no socioeconomic differences were found between patients and controls in this study.

Published
2016
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