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Your search keyword '"Shim, Hyun-Jin"' showing total 29 results
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29 results on '"Shim, Hyun-Jin"'

1. Star Formation and AGN activity in Galaxies classified using the 1.6 {\mu}m Bump and PAH features at $z = 0.4-2$

Author

Hanami, Hitoshi, Ishigaki, Tsuyoshi, Fujishiro, Naofumi, Nakanishi, Kouichiro, Miyaji, Takamitsu, Krumpe, Mirko, Umetsu, Keiichi, Ohyama, Youichi, Shim, Hyun Jin, Im, Myungshin, Lee, Hyoung Mok, Lee, Myung Gyoon, Serjeant, Stephen, White, Glenn J., Willmer, Christopher N., Goto, Tomotsugu, Oyabu, Shinki, Takagi, Toshinobu, Wada, Takehiko, and Matsuhara, Hideo

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We have studied the star-formation and AGN activity of massive galaxies in the redshift range $z=0.4-2$, which are detected in a deep survey field using the AKARI InfraRed (IR) astronomical satellite and {\em Subaru} telescope toward the North Ecliptic Pole (NEP). The AKARI/IRC Mid-InfraRed (MIR) multiband photometry is used to trace their star-forming activities with the Polycyclic-Aromatic Hydrocarbon (PAH) emissions, which is also used to distinguish star-forming populations from AGN dominated ones and to estimate the Star Formation Rate (SFR) derived from their total emitting IR (TIR) luminosities. In combination with analyses of their stellar components, we have studied the MIR SED features of star-forming and AGN-harboring galaxies., Comment: 45 pages and 63 figures, will be published in PASJ Vol.64 No.4

Published
2011
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2. North Ecliptic Pole Wide Field Survey of AKARI: Survey Strategy and Data Characteristics

Author

Lee, Hyung Mok, Kim, Seong Jin, Im, Myungshin, Matsuhara, Hideo, Oyabu, Shinki, Wada, Takehiko, Nakagawa, Takao, Ko, Jongwan, Shim, Hyun Jin, Lee, Myung Gyoon, Hwang, Narae, Takagi, Toshinobu, and Pearson, Chris

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We present the survey strategy and the data characteristics of the North Ecliptic Pole (NEP) Wide Survey of AKARI. The survey was carried out for about one year starting from May 2006 with 9 passbands from 2.5 to 24 micron and the areal coverage of about 5.8 sq. degrees centered on NEP. The survey depth reaches to 21.8 AB magnitude near infrared (NIR) bands, and ~ 18.6 AB maggnitude at the mid infrared (MIR) bands such as 15 and 18 micron. The total number of sources detected in this survey is about 104,000, with more sources in NIR than in the MIR. We have cross matched infrared sources with optically identified sources in CFHT imaging survey which covered about 2 sq. degrees within NEP-Wide survey region in order to characterize the nature of infrared sources. The majority of the mid infrared sources at 15 and 18 micron band are found to be star forming disk galaxies, with smaller fraction of early type galaxies and AGNs. We found that a large fraction (60~80 %) of bright sources in 9 and 11 micron stars while stellar fraction decreases toward fainter sources. We present the histograms of the sources at mid infrared bands at 9, 11, 15 and 18 micron. The number of sources per magnitude thus varies as m^0.6 for longer wavelength sources while shorter wavelength sources show steeper variation with m, where m is the AB magnitude., Comment: 18 pages, 11 figures, to appear in PASJ, Vol. 61, No. 2. April 25, 2009 issue

Published
2009
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6. Aster yomena suppresses LPS-induced cyclooxygenase-2 and inducible nitric oxide synthase expression

Author

Shim Hyun-Jin, Youn Hyung-Sun, Kim Ji-Soo, Ahn Sang-Il, Hwang Kyung-A, Kim Ah-Yeon, Nam Kung-Woo, and Shin Hyeon-Myeong

Subjects
0301 basic medicine, INSECT BITES, biology, business.industry, Immunology, Pharmacology, Proinflammatory cytokine, Nitric oxide synthase, 03 medical and health sciences, IκBα, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Biochemistry, chemistry, 030220 oncology & carcinogenesis, biology.protein, Medicine, Cyclooxygenase, Nitrite, business, Agronomy and Crop Science, Gene, Aster yomena, Food Science
Abstract

Inflammation is a pathological process that is known to be involved in numerous diseases. Microbial infection or tissue injury activates inflammatory responses, resulting in the induction of proinflammatory proteins including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Aster yomena is used in traditional Korean remedies to treat cough, asthma, and insect bites. Here, we investigated the effects of A. yomena extract (EAY) on the expression of COX-2 and iNOS induced by LPS. EAY inhibited NF-κB activation and IκBα degradation induced by LPS. EAY suppressed LPS-induced COX-2 and iNOS expression which are the target genes regulated through NF-κB activation in macrophages. EAY also suppressed LPS-induced nitrite production. These results suggest that EAY has the potential to be developed as a potent anti-inflammatory drug.

Published
2016

11. Aster yomena suppresses LPS-induced cyclooxygenase-2 and inducible nitric oxide synthase expression

Author

Kim, Ji-Soo, Ah-Yeon Kim, Hyeon-Myeong Shin, Ahn, Sang-Il, Shim, Hyun-Jin, Kung-Woo Nam, Kyung-A Hwang, and Hyung-Sun Youn

Abstract

Inflammation is a pathological process that is known to be involved in numerous diseases. Microbial infection or tissue injury activates inflammatory responses, resulting in the induction of proinflammatory proteins including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). Aster yomena is used in traditional Korean remedies to treat cough, asthma, and insect bites. Here, we investigated the effects of A. yomena extract (EAY) on the expression of COX-2 and iNOS induced by LPS. EAY inhibited NF-κB activation and IκBα degradation induced by LPS. EAY suppressed LPS-induced COX-2 and iNOS expression which are the target genes regulated through NF-κB activation in macrophages. EAY also suppressed LPS-induced nitrite production. These results suggest that EAY has the potential to be developed as a potent anti-inflammatory drug.

Published
2016
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19. Eicosapentaenoic acid suppresses TRIF‐dependent signaling pathway of TLRs by targeting TBK1.

Author

Shin, Hyeon‐Myeong, Shim, Hyun‐Jin, Kim, Ah‐Yeon, Lee, Yoo Jung, Nam, Hyeonjeong, and Youn, Hyung‐Sun

Subjects
*EICOSAPENTAENOIC acid, *INTERFERONS, *TOLL-like receptors, *SERINE/THREONINE kinases, *INTERLEUKIN-1 receptors
Abstract

Abstract: Toll‐like receptors (TLRs) induce an innate immune system. In general, there are two main pathways in TLRs: the myeloid differentiation primary response protein 88 (MyD88)‐dependent and toll‐interleukin‐1 receptor domain‐containing adapter‐inducing interferon‐β (TRIF)‐dependent pathways. In this study, it has been investigated whether eicosapentaenoic acid (EPA), a polyunsaturated fatty acid (PUFA), and arachidic acid (ACA), a saturated fatty acid (SFA), can modulate the TLR signaling pathways. EPA suppressed the activation of interferon regulatory factor 3 (IRF3) and the expression of Interferon gamma‐induced protein (IP‐10) induced by Toll‐like receptor 3 (TLR3) or TLR4 agonists by targeting TANK‐binding kinase 1 (TBK1); however, ACA did not. These results demonstrate that EPA inhibits the TRIF‐dependent signaling in the TLR3 and TLR4 pathways. The results raise the possibility that certain dietary PUFAs can modulate TLR‐derived signaling and inflammatory target gene expression and can alter the susceptibility to microbial infection and chronic inflammatory diseases. Practical application: Eicosapentaenoic acid (EPA) is a bioactive lipid that modulates inflammation and immunity. TLRs play a central role as initiators of the innate immune responses. EPA regulates TRIF‐dependent pathways of TLRs by targeting TBK1. EPA may be a useful strategy to understand the mechanism of antiinflammatory activities. [ABSTRACT FROM AUTHOR]

Published
2018
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20. Aster yomena suppresses LPS-induced cyclooxygenase-2 and inducible nitric oxide synthase expression.

Author

Kim, Ji-Soo, Kim, Ah-Yeon, Shin, Hyeon-Myeong, Ahn, Sang-Il, Shim, Hyun-Jin, Nam, Kung-Woo, Hwang, Kyung-A, and Youn, Hyung-Sun

Subjects
INFLAMMATION treatment, CYCLOOXYGENASE 2, NITRIC-oxide synthases, PROTEIN expression, ASTERACEAE
Abstract

Inflammation is a pathological process that is known to be involved in numerous diseases. Microbial infection or tissue injury activates inflammatory responses, resulting in the induction of proinflammatory proteins including cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS).Aster yomenais used in traditional Korean remedies to treat cough, asthma, and insect bites. Here, we investigated the effects ofA. yomenaextract (EAY) on the expression of COX-2 and iNOS induced by LPS. EAY inhibited NF-κB activation and IκBα degradation induced by LPS. EAY suppressed LPS-induced COX-2 and iNOS expression which are the target genes regulated through NF-κB activation in macrophages. EAY also suppressed LPS-induced nitrite production. These results suggest that EAY has the potential to be developed as a potent anti-inflammatory drug. [ABSTRACT FROM AUTHOR]

Published
2017
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29. North Ecliptic Pole Wide Field Survey of AKARI: Survey Strategy and Data Characteristics

Author

Lee, Hyung Mok, primary, Kim, Seong Jin, additional, Im, Myungshin, additional, Matsuhara, Hideo, additional, Oyabu, Shinki, additional, Wada, Takehiko, additional, Nakagawa, Takao, additional, Ko, Jongwan, additional, Shim, Hyun Jin, additional, Lee, Myung Gyoon, additional, Hwang, Narae, additional, Takagi, Toshinobu, additional, and Pearson, Chris, additional

Published
2009
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