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This paper introduces a bio-inspired metaheuristic optimization algorithm named Tunicate Swarm Algorithm (TSA). The proposed algorithm imitates jet propulsion and swarm behaviors of tunicates during the navigation and foraging process. The performance of TSA is evaluated on seventy-four benchmark test problems employing sensitivity, convergence and scalability analysis along with ANOVA test. The efficacy of this algorithm is further compared with several well-regarded metaheuristic approaches based on the generated optimal solutions. In addition, we also executed the proposed algorithm on six constrained and one unconstrained engineering design problems to further verify its robustness. The simulation results demonstrate that TSA generates better optimal solutions in comparison to other competitive algorithms and is capable of solving real case studies having unknown search spaces. Note that the source codes of the proposed TSA algorithm are available at [ABSTRACT FROM AUTHOR]