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Background: Dengue is one of the most common arboviral infection in the world. Evaluation of the clinical parameters for the early diagnosis of the disease is used to assist the preventive strategies. This study aimed to evaluate the hematological and biochemical parameters retrospectively in patients with serologically confirmed dengue infection over a one-year period. Method: The study was conducted in clinical laboratories of a tertiary care hospital serving the people of Karnataka and neighbouring states. A retrospective analysis of known IgM and anti-NS1 seropositive dengue patients over a period of one year was done to evaluate the hematological and biochemical data for any significant variations. Results: A total of 108 patients were studied. 100 (92.60%) patients had Dengue Fever, 4 (3.70%) had Dengue haemorrhagic Fever, and 4 (3.70%) had Dengue Shock Syndrome. Thrombocytopenia in 87 (80.60%) cases, elevated AST in 92 (85.2%) and raised CK/CPK level observed in 50% of the cases. Conclusion: The alterations in hematological and biochemical parameters is associated with the patient case history and the clinical diagnosis. [ABSTRACT FROM AUTHOR]

Primary urinary Bladder Adenocarcinoma (PBA) is an uncommon neoplasm and can cause diagnostic difficulties due to histologic similarities with adenocarcinomas of adjacent structures like Gastrointestinal Tract (GIT) and prostate, since involvement of the bladder by metastasis or direct spread can occur. Seven cases of bladder adenocarcinomas were diagnosed during a period of four years in a tertiary care hospital. Patient's age ranged from 26-78 years with a male predilection. Three cases were signet ring type adenocarcinomas, two cases were subtyped as enteric variant, one as mucinous variant and one as adenocarcinoma Not Otherwise Specified (NOS) variant. One case showed urachal involvement. Common site of involvement was the base and posterior wall of the bladder. Three cases had prior history of GIT malignancy. No morphologic difference was identified to differentiate primary from secondary adenocarcinomas. Bladder adenocarcinoma is rare tumours. Primary and secondary adenocarcinomas cannot be distinguished from each other on morphologic grounds. Ancillary studies may have limited role in distinguishing between the two. Hence, clinical correlation has a major role in their evaluation. [ABSTRACT FROM AUTHOR]

Dressler's syndrome is pericarditis which develops 2-10 weeks after myocardial infarction or due to a traumatic etiology. Dressler's syndrome is an immune system response that damages the heart tissues or pericardium secondary to events like myocardial infarction, heart surgery, or traumatic injury with incidence of 3-4 %. This is usually diagnosed in autopsy due to the narrow treatment window which makes clinical diagnosis difficult. This case highlights the rare condition called Dressler's syndrome. [ABSTRACT FROM AUTHOR]