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Background: This paper addresses the question of whether a sociology of mental health is possible. This question raises the issue of the theoretical conditions necessary to establish a sub-field, and requires a debate about the boundaries and epistemological status of such an enterprise. Aim: To analyse the various historical building blocks and contexts relevant to understanding the contemporary expression and state of a sociological perspective on mental health in France. Method: Literature review and a current empirical research about the politics of distress and psychoanalysis as case study, used to discuss the genesis and development of French sociological influences from a historical epistemological framework. Results: The context and limitations of previous social approaches to the study of mental health and suggestions as to the future direction of a sociology of mental health in a French context are discussed, centring around relevant influences and interests. Implications: The use of an interactionist orientation combined with a critical analysis of psychoanalysis in the context of contemporary social conditions lays the foundation upon which to recapture a sociology applied to mental health. Declaration of interest: None. [ABSTRACT FROM AUTHOR]