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An efficient enantioselective Michael addition of benzofuran-2(3 H )-ones to alkylideneindolenines generated in situ from arenesulfonylalkylindoles has been described, and a series of optically active C-3 alkyl-substituted benzofuran-2(3 H )-one derivatives containing indole skeleton with two adjacent stereocenters have been obtained. The resulting adduct can readily be converted to chiral o -hydroxyphenylacetic acid derivative with indole motif. [ABSTRACT FROM AUTHOR]

The title process allows the synthesis of a series of optically active indole derivatives with enantioselectivities up to 94%. [ABSTRACT FROM AUTHOR]

Abstract: An efficient enantioselective Michael addition of 2-naphthols to alkylideneindolenines generated in situ from arenesulfonylalkylindoles has been described. The protocol provides an efficient and convenient access to C-3 alkyl-substituted indole derivatives containing phenolic hydroxyl groups with high yields (up to 96%) and enantioselectivities (up to 98% ee) under mild conditions. [Copyright &y& Elsevier]

Abstract: An efficient stereoselective Michael addition of simple 3(2H)-furanones to α,β-unsaturated ketones has been described. The protocol provides a facile and efficient access to complex 3(2H)-furanones containing adjacent quaternary and tertiary stereocenters in high yields (up to 99%) with good diastereoselectivities (up to 86:14) and excellent enantioselectivities (up to 98%ee) under mild conditions. [Copyright &y& Elsevier]

Asymmetric Michael addition of furanones to α,β-unsaturated aldehydes followed by reduction of the addition products provides optically active alcohols with high enantioselectivities and low to moderate diastereoselectivities. [ABSTRACT FROM AUTHOR]

Michael addition of furanones to α,β-unsaturated ketones in the presence of a cinchona-based chiral catalyst provides the title products (III) with high enantioselectivity and low to moderate diastereoselectivity. [ABSTRACT FROM AUTHOR]

A diagram is presented which shows the organocatalytic Michael reaction of alkylideneindolenines and 2-naphthols that were generated from arenesulfonylalkylindoles.