1. Migration of fully covered self-expandable metallic stents used to treat anastomotic strictures after orthotopic liver transplantation
- Author
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Ding, Songming, Wu, Weilin, Lu, Jianfang, Zhu, Hengkai, Zheng, Shusen, and Li, Qiyong
- Subjects
Cholangiopancreatography, Endoscopic Retrograde ,Male ,anastomotic stricture ,endoscopic retrograde cholangiopancreatography ,fully covered self-expandable metallic stent ,Self Expandable Metallic Stents ,Observational Study ,Bilirubin ,Constriction, Pathologic ,Middle Aged ,Liver Transplantation ,Treatment Outcome ,aspartate aminotransferase ,orthotopic liver transplantation ,Living Donors ,Humans ,Female ,Aspartate Aminotransferases ,Research Article ,Retrospective Studies - Abstract
Insertion of a fully covered self-expandable metallic stent (FCEM) through endoscopic retrograde cholangiopancreatography is an effective solution for biliary anastomotic stricture following orthotopic liver transplantation (OLT). However, FCEM migration continues to plague patients. This study aimed to evaluate the FCEM migration rate in our center, and to investigate the factors increasing the migration risk for FCEM. The study enrolled 43 post-OLT patients with confirmed duct-to-duct AS. The effects of age, gender, albumin, alanine aminotransferase, aspartate aminotransferase (AST), γ-glutamyl transpeptidase, alkaline phosphatase, total bilirubin, direct bilirubin, ABO (blood group system consists of four antigens) incompatibility, stricture length, FCEM brand, FCEM length, donor liver and recipient bile duct diameters, size mismatches between the donor and recipient bile ducts >2 mm, diabetes and/or hypertension status, endoscopic sphincterotomy status, the use of plastic stents or nasobiliary drainage prior to FCEM implantation, duration from OLT to FCEM placement, and OLT etiology on FCEM migration were retrospectively analyzed. The FCEM migration rate was 48.8% (21/43) at 6 months. The serum AST level was significantly higher in the migration group than that in the nonmigration group (52.48 vs 29.50 U/L, P
- Published
- 2022