1. Association of Vitamin D Deficiency and Insufficiency with Pathology in Hospitalized Patients.
- Author
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Bucurica, Sandica, Prodan, Ioana, Pavalean, Mihaela, Taubner, Corina, Bucurica, Ana, Socol, Calin, Calin, Roxana, Ionita-Radu, Florentina, and Jinga, Mariana
- Subjects
VITAMIN D deficiency ,HOSPITAL patients ,VITAMIN D ,CARDIOVASCULAR diseases ,PATHOLOGY - Abstract
Vitamin D deficiency is one of the most common medical conditions, with approximately one billion people having low vitamin D levels. Vitamin D is associated with a pleiotropic effect (immunomodulatory, anti-inflammatory and antiviral), which can be essential for a better immune response. The aim of this research was to evaluate the prevalence of vitamin D deficiency/insufficiency in hospitalized patients focusing on demographic parameters as well as assessing the possibility of its associations with different comorbidities. Of 11,182 Romanian patients evaluated in the study over 2 years, 28.83% had vitamin D deficiency, 32.11% insufficiency and 39.05% had optimal vitamin D levels. The vitamin D deficiency was associated with cardiovascular disorders, malignancies, dysmetabolic disorders and SARS-CoV2 infection, older age and the male sex. Vitamin D deficiency was prevalent and showed pathology association, while insufficiency of vitamin D (20–30 ng/mL) had lower statistical relevance and represents a grey zone in vitamin D status. Guidelines and recommendations are necessary for homogeneity of the monitoring and management of inadequately vitamin D status in the risk categories. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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