4 results on '"Li, Xuehang"'
Search Results
2. Association of Sleep Status With Cognitive Functions in Centenarians: Evidence From Hainan Centenarian Cohort.
- Author
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Yang, Shanshan, Wang, Shengshu, Liu, Guangdong, Li, Rongrong, Li, Xuehang, Chen, Shimin, Wang, Jianhua, Zhao, Yali, Liu, Miao, and He, Yao
- Subjects
COGNITION disorder risk factors ,SLEEP quality ,RESEARCH ,MEMORY ,CENTENARIANS ,CONFIDENCE intervals ,SLEEP latency ,MENTAL orientation ,SLEEP duration ,PATIENT monitoring ,ATTENTION ,COGNITIVE testing ,LOGISTIC regression analysis ,ODDS ratio ,OLD age - Abstract
Objectives This study aimed to analyze the association between sleep quality, sleep duration, and cognitive functions among centenarians. Methods The baseline data of the China Hainan Centenarians Cohort Study served as the foundation for this study. Logistic regression was utilized to demonstrate the relationship between sleep status and cognitive impairment. Moreover, a canonical correlation analysis was performed to analyze the correlation between these variables. Results A total of 994 centenarians were included. After adjustment, poor sleep quality centenarians had an odds ratio of 1.77 (95% confidence interval [CI]: 1.00–3.09) for cognitive impairment when compared to centenarians with normal sleep quality. Centenarians who slept for more than 9 hr had a stronger association with severe cognitive impairment, indicated by an odds ratio of 1.41 (95% CI: 1.02–1.96), compared to those who slept for 7–9 hr. Additionally, the canonical correlation analysis results revealed that the linear combination of sleep quality V1, primarily determined by sleep latency, daytime dysfunction, and subjective sleep quality, was associated with cognitive function; the linear combination of cognitive function W1, mainly determined by orientation, attention and calculation, and memory. Discussion There exists a correlation between poor sleep quality and cognitive impairment in centenarians, as well as a correlation between sleep duration >9 hr at night and severe cognitive impairment. The primary cognitive domains associated with sleep quality are orientation, calculation, and memory. It is imperative to monitor and safeguard the cognitive functions linked to poor sleep quality in the older individuals, with attention to orientation, calculation, and memory. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
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3. Cardiometabolic diseases and early cognitive decline: Mitigated by integrated active lifestyle for brain health.
- Author
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Li, Haowei, Qi, Shige, Wang, Shengshu, Yang, Shanshan, Liu, Shaohua, Chen, Shimin, Li, Xuehang, Li, Rongrong, Yang, Junhan, Li, Huaihao, Bao, Yinghui, Shi, Yueting, Wang, Zhihui, Liu, Miao, and He, Yao
- Subjects
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COGNITION disorders , *HEART metabolism disorders , *SLEEP quality , *UNHEALTHY lifestyles , *CONSCIOUSNESS raising , *MEDICAL personnel - Abstract
Cardiometabolic diseases (CMDs) increases the risk of cognitive decline, but the extent to which this can be offset by adherence to an active integrated lifestyle is unknown. This prospective study used the baseline and 2-year follow-up data of 2537 dementia-free elderly ≥60 from PINDEC Project. Lifestyle factors (including physical exercise, social interaction, leisure activities, sleep quality, smoking, and alcohol consumption) were collected and the integrated score was calculated. Participants were divided into three groups based on integrated score tertiles (inactive, ≤3 score; intermediate, 4 score; and active, ≥5). Logistic regression was used in data analysis. 35.2 % participants had 5–6 healthy components, while only 5.4 % had all 6 healthy lifestyles. The multiadjusted odds ratios (ORs, 95 % confidence interval) of early cognitive decline was 1.223 (0.799–1.871) and 1.832 (1.140–2.943) for participants with only one CMD and any two or more CMDs, respectively. An inverse dose-response relationship was found between lifestyle scores and early cognitive decline (P trend = 0.017). In participants with active lifestyle, the OR for early cognitive decline comparing the CMDs status of any two or more CMDs vs. CMDs-free was 0.778 (95%CI: 0.302–2.007). Participants with inactive lifestyle and any two or more CMDs had a near 3.4-fold increased risk of early cognitive decline than those without CMDs who had intermediate to active lifestyle (OR = 3.422, 95%CI: 1.764–6.638). Our research lacks information about nutrition. A dose–response relationship exists between CMDs status and risk of early cognitive decline. However, adherence to an active integrated lifestyle may mitigate this risk. • Lifestyle played a moderating roleon the association between CMDs status and early cognitive decline among older adults. • The association between CMDs status and early cognitive decline was attenuated in older adults with active lifestyle. • Medical staff should focus on raising awareness of the importance of brain-health-related healthy lifestyles in older adults. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Association of sleep status with depressive state in centenarians: Evidence from Hainan centenarian cohort.
- Author
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Yang, Shanshan, Han, Ke, Wang, Shengshu, Li, Rongrong, Li, Xuehang, Chen, Shimin, Zhao, Yali, Liu, Guangdong, Liu, Miao, and He, Yao
- Subjects
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SLEEP duration , *CENTENARIANS , *SLEEP quality , *OLDER people , *SLEEP , *ODDS ratio - Abstract
The objective of this study is to analyze the association between sleep quality, sleep duration, sleep patterns, and depressive states among centenarians due to the crucial impact of depression on the well-being of elderly individuals, particularly the oldest. Recognizing easily identifiable manifestations and risk factors is essential since the onset of depressive states tends to be insidious. The baseline data from the China Hainan Centenarians Cohort Study (CHCCS) served as the basis for this study. Questionnaire surveys were conducted to obtain research indicators, with depressive states evaluated using the GDS-15 scale and sleep quality evaluated using the Pittsburgh Sleep Quality Index (PSQI). Logistic regression was employed to describe the association between sleep status and depressive states. A total of 994 centenarians, with an age range of 100–116 years and a mean age of 102.77 ± 2.75 years, were included in this study. Among these participants, 815 were female, accounting for 82.0 %. After adjustment, the odds ratio (OR) for the association between poor sleep quality and depressive states was 2.07 (95 % CI: 1.54–2.77) compared to those with normal sleep quality. Additionally, there were associations between depressive states and both nighttime sleep duration and total sleep duration. After adjustment, the strongest association between depressive state and sleep patterns was found for those who had >9 h of nighttime sleep and ≥2 h of daytime sleep (OR = 1.80, 95%CI: 1.02–3.16). Moreover, compared to centenarians with 7–9 h of sleep duration and good sleep quality, the highest odds ratio (OR = 3.44, 95%CI: 2.18–5.43) for the association between depressive states and sleep duration ≤7 h and poor sleep quality was observed. The findings of this study indicate that there is an association between poor sleep quality and depressive states in centenarians. Furthermore, both sleep quality and long/short total sleep duration are associated with depressive states in this population. Therefore, special attention should be given to the psychological state of elderly individuals with short sleep duration and poor sleep quality in order to prevent depression and minimize its negative impact on their overall health. • This is a study of a large sample centenarians in China, Hainan. • Analyzed the association between sleep quality, sleep duration, sleep patterns, and depressive states among centenarians. • There was an association between poor sleep quality and depressive states in centenarians. • Both sleep quality and long/short total sleep duration were associated with depressive states in centenarians. • Gender differences in the association between nighttime sleep duration and depressive state exist. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
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