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Twelve new 9,10-secosteroids designated as subergorgiaols A–L ( 1 – 12 ), along with four known analogues ( 13 – 16 ), were isolated from the gorgonian Subergorgia rubra collected from the South China Sea . Their planar structures and the relative configurations were elucidated by comprehensive spectroscopic methods including NOESY spectra. The absolute configuration of 1 was established by a dimolybdenum tetraacetate [Mo 2 (AcO) 4 ] induced circular dichroism (ICD) procedure and the modified Mosher’s method. Compounds 1 – 12 represent the first series of 9,10-secosteroids characterized with a hydroxy group at C-8, which are 8-OH derivatives of astrogorgiadiols/calicoferols. Compound 4 exhibited cytotoxicity against the cervical carcinoma cell line (CaSki) with an IC 50 value of 2.4 μM, and 6 showed toxicity toward brine shrimp Artemia salina with an LC 50 value of 2.0 μM. [ABSTRACT FROM AUTHOR]

The article focuses on the South China Sea's Gorgonian Subergorgia suberosa species and its chemical composition. Other topics addressed include their presence in the Indo-Pacific Ocean's subtropical and tropical waters, structure elucidation, and isolated compounds. Molecular structures of the compounds are also included.

The article focuses on a study related to brominated polyunsaturated lipids and steroids from the South China Sea sponge haliclona subarmigera. It discusses origination of the species along with an analysis of its isolation from current state. It further mentions medicinal properties of the species and how it is used as medical treatment in various places. It also presents chemical bonding of the process.

The article focuses on a study related to briarane diterpenoids from gorgonian dichotella gemmacea collected from the South China Sea. It discusses various biological activities of Dichotella gemmacea, such as antifouling, cytotoxic, and anti-inflammatory. It also discusses screening for bioactive natural products from marine invertebrates.