Search

Copyright of Journal of Engineering Geology / Gongcheng Dizhi Xuebao is the property of Journal of Engineering Geology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Hydrogeology & Engineering Geology / Shuiwendizhi Gongchengdizhi is the property of Hydrogeology & Engineering Geology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In order to explore the grouting materials suitable for the fracture reinforcement of Jinsha soil site, three kinds of grouting materials were prepared by mixing calcined ginger nut, SH and inorganic mineral polymer with the test soil of Jinsha site. Through laboratory tests, the basic physical properties, mechanical properties and durability of various grouting materials were analyzed in detail. The results show that the inorganic mineral polymer grouting material has low shrinkage and can effectively fill the cracks. At the same time, its high flexural and compressive strength provides a reliable guarantee for improving the mechanical stability of earthen sites. Among the three grouting materials studied, the inorganic mineral polymer grouting material exhibits the best durability. Therefore, it is recommended to use inorganic mineral polymer grouting materials in the crack grouting reinforcement project of Jinsha soil site. The research results will provide useful guidance for the selection and application of crack grouting materials in soil sites under humid environment. [ABSTRACT FROM AUTHOR]

The preparation mechanism and liquefaction mechanism is reviewed, then the preparation method and modification mechanism of bio-asphalt is given, and the research situation and development prospects of bio-asphalt are concluded at home and abroad.Compared with traditional asphalt, bio-asphalt has better road performance, economic and environmental benefits, and could be used as a good substitute for traditional road asphalt. [ABSTRACT FROM AUTHOR]

Objective：To investigate the role of microbes in colorectal cancer liver metastases(CRLM)and the underlying mechanisms. Methods：16S rDNA sequencing was performed on colon tumors and liver tumors in CRLM patients. The mouse model of CRLM was established and treated with antibiotics, Escherichia coli(E.coli), lactate dehydrogenase inhibitor and clodronate liposome. After 24 days, the liver tumor tissues were obtained for HE staining, immunofluorescence staining and detection of lactate concentration and microbial abundance. E. coli and MC38 cells were co - cultured at 100∶1. The cell proliferation, the extracellular acidification rate(ECAR)and concentration of lactate was determined by CCK8, Seahorse and colorimetry respectively. Macrophages (MØ)derived from mouse bone marrow were treated with lactate, lactylation antibody and TNF-α respectively. The expression levels of CD206 and iNOS were detected by immunofluorescence；the mRNA levels of iNOS, CD86, CD163 and ARG were detected by qPCR; The lactylation level and NF-κB expression were detected by Western Blot. Results：There were microbes in colon and liver tumors in CRLM patients and the dominant species were similar. Microbiota promoted liver metastasis of colorectal cancer in mice and MØ was found to be M2 - like polarized, while the liver metastases decreased after depletion of MØ. Microbiota could not enhance the proliferation of tumor cells, but could increase the level of tumor glycolysis and lactate and inhibition of lactate dehydrogenase could reduce liver metastases in mice.Lactate could induce MØ polarization to M2 and lactylation. RIG - Ilys852 was found to inhibit the polarization of MØ induced by lactate;the expression of NF -κB was decreased after macrophage treated with lactate;TNF -α could inhibit MØ polarization to M2. Conclusion:Microbes enhance the level of glycolysis and lactate in tumor and promote liver metastasis of colorectal cancer via macrophage RIG-I lactylation. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Chinese Mass Spectrometry Society is the property of Journal of Chinese Mass Spectrometry Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Shandong Medical Journal is the property of Shandong Medical Health Newspapers and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Wuhan University Journal (Philosophy & Social Sciences) / Wuhan Daxue Xuebao (Zhexue Shehui Kexue Ban) is the property of Wuhan University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)