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Your search keyword '"Andreas Gonschorek"' showing total 3 results
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3 results on '"Andreas Gonschorek"'

1. Prospective observational cohort study on epidemiology, treatment and outcome of patients with traumatic brain injury (TBI) in German BG hospitals

Author

Peter Schwenkreis, Andreas Gonschorek, Florian Berg, Ullrich Meier, Witold Rogge, Ingo Schmehl, Bodo Christian Kern, Hans-Jörg Meisel, Kai Wohlfarth, Stefan Gross, Matthias Sczesny-Kaiser, Martin Tegenthoff, Jürgen Boschert, Ralf Bruckmoser, Andrea Fürst, Marc Schaan, Martin Strowitzki, Andreas Pingel, Lisa Linnea Jägers, Henrik Rudolf, Hans-Joachim Trampisch, and Johannes Lemcke

Subjects
Medicine
Abstract

Objectives Since 2000/2001, no large-scale prospective studies addressing traumatic brain injury (TBI) epidemiology in Germany have been published. Our aim was to look for a possible shift in TBI epidemiology described in other European countries, to look for possible changes in TBI management and to identify predictors of 1-year outcome especially in patients with mild TBI.Design Observational cohort study.Setting All patients suffering from a TBI of any degree between 1 October 2014 and 30 September 2015, and who arrived in one of the seven participating BG hospitals within 24 hours after trauma, were included.Participants In total, 3514 patients were included.Outcome measures Initial care, acute hospital care and rehabilitation were documented using standardised documentation forms. A standardised telephone interview was conducted 3 and 12 months after TBI in order to obtain information on outcome.Results Peaks were identified in males in the early 20s and mid-50s, and in both sexes in the late 70s, with 25% of all patients aged 75 or older. A fall was the most frequent cause of TBI, followed by traffic accidents (especially bicyclists). The number of head CT scans increased, and the number of conventional X-rays of the skull decreased compared with 2000/2001. Besides, more patients were offered rehabilitation than before. Though most TBI were classified as mild, one-third of the patients participating in the telephone interview after 12 months still reported troubles attributed to TBI. Negative predictors in mild TBI were female gender, intracranial bleeding and Glasgow Coma Scale (GCS) 13/14.Conclusion The observed epidemiologic shift in TBI (ie, elderly patients, more falls, more bicyclists) calls for targeted preventive measures. The heterogeneity behind the diagnosis ‘mild TBI’ emphasises the need for defining subgroups not only based on GCS.

Published
2021
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2. Non-invasive brain microcurrent stimulation therapy of long-COVID-19 reduces vascular dysregulation and improves visual and cognitive impairment

Author

Bernhard A. Sabel, Wanshu Zhou, Frank Huber, Florentina Schmidt, Kornelia Sabel, Andreas Gonschorek, and Mirela Bilc

Subjects
Adult, cognition, restoration, Vision, Vision Disorders, Brain, COVID-19, Electric Stimulation Therapy, recovery, Post-Acute COVID-19 Syndrome, Developmental Neuroscience, Neurology, neuromodulation, Humans, Cognitive Dysfunction, Female, Neurology (clinical), corona, Aged, Research Article
Abstract

Background: An effective treatment is needed for long-COVID patients which suffer from symptoms of vision and/or cognition impairment such as impaired attention, memory, language comprehension, or fatigue. Objective: Because COVID-19infection causes reduced blood flow which may cause neuronal inactivation, we explored if neuromodulation with non-invasive brain stimulation using microcurrent (NIBS), known to enhance blood flow and neuronal synchronization, can reduce these symptoms. Methods: Two female long-COVID patients were treated for 10–13 days with alternating current stimulation of the eyes and brain. While one patient (age 40) was infected with the SARS CoV-2 virus, the other (age 72) developed symptoms following AstraZeneca vaccination. Before and after therapy, cognition was assessed subjectively by interview and visual fields quantified using perimetry. One patient was also tested with a cognitive test battery and with a retinal dynamic vascular analyser (DVA), a surrogate marker of vascular dysregulation in the brain. Results: In both patients NIBS markedly improved cognition and partially reversed visual field loss within 3–4 days. Cognitive tests in one patient confirmed recovery of up to 40–60% in cognitive subfunctions with perimetry results showing stable and visual field recovery even during follow-up. DVA showed that NIBS reduced vascular dysregulation by normalizing vessel dynamics (dilation/constriction), with particularly noticeable changes in the peripheral veins and arteries. Conclusions: NIBS was effective in improving visual and cognitive deficits in two confirmed SARS-COV-2 patients. Because recovery of function was associated with restoration of vascular autoregulation, we propose that (i) hypometabolic, “silent” neurons are the likely biological cause of long-COVID associated visual and cognitive deficits, and (ii) reoxygenation of these “silent” neurons provides the basis for neural reactivation and neurological recovery. Controlled trials are now needed to confirm these observations.

Published
2021

3. Common peroneal nerve palsy caused by a ganglion. Case report

Author

Andreas Gonschorek, Hisham Fansa, K. Plogmeier, and Helmut Feistner

Subjects
Male, medicine.medical_specialty, Neural Conduction, Paralysis, medicine, Humans, Palsy, medicine.diagnostic_test, business.industry, Common peroneal nerve palsy, Peripheral Nervous System Diseases, Peroneal Nerve, Magnetic resonance imaging, General Medicine, Anatomy, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Ganglion, Surgery, Ganglion cyst, medicine.anatomical_structure, Ganglia, medicine.symptom, business, Common peroneal nerve
Abstract

A common peroneal nerve palsy caused by a ganglion cyst is a rare entity. A 48-year old man was referred with a six year history of intermittent pain that had resulted in a complete palsy of the common peroneal nerve. A magnetic resonance (MR) scan showed compression of the nerve by a ganglion, which was excised and the nerve was released. Three months later the lost muscle function had returned completely.

Published
1998

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