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14 results on '"Arras, Guillaume"'

4. Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

Author

Jacquemin, Guillaume, primary, Wurmser, Annabelle, additional, Huyghe, Mathilde, additional, Sun, Wenjie, additional, Homayed, Zeinab, additional, Merle, Candice, additional, Perkins, Meghan, additional, Qasrawi, Fairouz, additional, Richon, Sophie, additional, Dingli, Florent, additional, Arras, Guillaume, additional, Loew, Damarys, additional, Vignjevic, Danijela, additional, Pannequin, Julie, additional, and Fre, Silvia, additional

Published
2022
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5. Author response: Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

Author

Jacquemin, Guillaume, primary, Wurmser, Annabelle, additional, Huyghe, Mathilde, additional, Sun, Wenjie, additional, Homayed, Zeinab, additional, Merle, Candice, additional, Perkins, Meghan, additional, Qasrawi, Fairouz, additional, Richon, Sophie, additional, Dingli, Florent, additional, Arras, Guillaume, additional, Loew, Damarys, additional, Vignjevic, Danijela, additional, Pannequin, Julie, additional, and Fre, Silvia, additional

Published
2022
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6. Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex

Author

Bizzotto, Sara, Uzquiano, Ana, Dingli, Florent, Ershov, Dmitry, Houllier, Anne, Arras, Guillaume, Richards, Mark, Loew, Damarys, Minc, Nicolas, Croquelois, Alexandre, Houdusse, Anne, Francis, Fiona, Francis, Fiona, Institut du Fer à Moulin (IFM - Inserm U1270 - SU), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Harvard Medical School [Boston] (HMS), Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Boston Children's Hospital, Laboratoire de Spectrométrie de Masse Protéomique, Institut Curie [Paris], Institut Jacques Monod (IJM (UMR_7592)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), University of Leicester, Université de Lausanne = University of Lausanne (UNIL), Biologie Cellulaire et Cancer, and Institut Curie [Paris]-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Cerebral Cortex, Mice, Knockout, [SDV]Life Sciences [q-bio], lcsh:R, lcsh:Medicine, Classical Lissencephalies and Subcortical Band Heterotopias, Spindle Apparatus, Article, [SDV] Life Sciences [q-bio], Mice, Neural Stem Cells, Animals, Female, lcsh:Q, lcsh:Science, Microtubule-Associated Proteins, Cells, Cultured, Cerebral Cortex/metabolism, Cerebral Cortex/pathology, Classical Lissencephalies and Subcortical Band Heterotopias/metabolism, Classical Lissencephalies and Subcortical Band Heterotopias/pathology, Microtubule-Associated Proteins/physiology, Neural Stem Cells/metabolism, Neural Stem Cells/pathology, Spindle Apparatus/metabolism, Spindle Apparatus/pathology
Abstract

International audience; The ventricular zone (VZ) of the developing cerebral cortex is a pseudostratified epithelium that contains progenitors undergoing precisely regulated divisions at its most apical side, the ventricular lining (VL). Mitotic perturbations can contribute to pathological mechanisms leading to cortical malformations. The HeCo mutant mouse exhibits subcortical band heterotopia (SBH), likely to be initiated by progenitor delamination from the VZ early during corticogenesis. The causes for this are however, currently unknown. Eml1, a microtubule (MT)-associated protein of the EMAP family, is impaired in these mice. We first show that MT dynamics are perturbed in mutant progenitor cells in vitro. These may influence interphase and mitotic MT mechanisms and indeed, centrosome and primary cilia were altered and spindles were found to be abnormally long in HeCo progenitors. Consistently, MT and spindle length regulators were identified in EML1 pulldowns from embryonic brain extracts. Finally, we found that mitotic cell shape is also abnormal in the mutant VZ. These previously unidentified VZ characteristics suggest altered cell constraints which may contribute to cell delamination.

Published
2017

7. Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme

Author

Jacquemin, Guillaume, primary, Wurmser, Annabelle, additional, Huyghe, Mathilde, additional, Sun, Wenjie, additional, Homayed, Zeinab, additional, Merle, Candice, additional, Perkins, Meghan, additional, Qasrawi, Fairouz, additional, Richon, Sophie, additional, Dingli, Florent, additional, Arras, Guillaume, additional, Loew, Damarys, additional, Vignjevic, Danijela, additional, Pannequin, Julie, additional, and Fre, Silvia, additional

Published
2020
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10. Live Tracking of Inter-organ Communication by Endogenous Exosomes In Vivo

Author

Verweij, Frederik J., primary, Revenu, Celine, additional, Arras, Guillaume, additional, Dingli, Florent, additional, Loew, Damarys, additional, Pegtel, D. Michiel, additional, Follain, Gautier, additional, Allio, Guillaume, additional, Goetz, Jacky G., additional, Zimmermann, Pascale, additional, Herbomel, Philippe, additional, Del Bene, Filippo, additional, Raposo, Graça, additional, and van Niel, Guillaume, additional

Published
2019
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11. Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling

Author

Forget, Antoine, primary, Martignetti, Loredana, additional, Puget, Stéphanie, additional, Calzone, Laurence, additional, Brabetz, Sebastian, additional, Picard, Daniel, additional, Montagud, Arnau, additional, Liva, Stéphane, additional, Sta, Alexandre, additional, Dingli, Florent, additional, Arras, Guillaume, additional, Rivera, Jaime, additional, Loew, Damarys, additional, Besnard, Aurore, additional, Lacombe, Joëlle, additional, Pagès, Mélanie, additional, Varlet, Pascale, additional, Dufour, Christelle, additional, Yu, Hua, additional, Mercier, Audrey L., additional, Indersie, Emilie, additional, Chivet, Anaïs, additional, Leboucher, Sophie, additional, Sieber, Laura, additional, Beccaria, Kevin, additional, Gombert, Michael, additional, Meyer, Frauke D., additional, Qin, Nan, additional, Bartl, Jasmin, additional, Chavez, Lukas, additional, Okonechnikov, Konstantin, additional, Sharma, Tanvi, additional, Thatikonda, Venu, additional, Bourdeaut, Franck, additional, Pouponnot, Celio, additional, Ramaswamy, Vijay, additional, Korshunov, Andrey, additional, Borkhardt, Arndt, additional, Reifenberger, Guido, additional, Poullet, Patrick, additional, Taylor, Michael D., additional, Kool, Marcel, additional, Pfister, Stefan M., additional, Kawauchi, Daisuke, additional, Barillot, Emmanuel, additional, Remke, Marc, additional, and Ayrault, Olivier, additional

Published
2018
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12. Live tracking of inter-organ communication by endogenous exosomes in vivo

Author

Verweij, Frederik J, primary, Revenu, Celine, additional, Arras, Guillaume, additional, Dingli, Florent, additional, Loew, Damarys, additional, Follain, Gautier, additional, Allio, Guillaume, additional, Goetz, Jacky G., additional, Herbomel, Philippe, additional, Bene, Filippo Del, additional, Raposo, Graça, additional, and van Niel, Guillaume, additional

Published
2018
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13. CSIG-15. PROTEOMIC AND PHOSPHOPROTEOMIC ANALYSIS OF HUMAN MEDULLOBLASTOMA REVEALS DISTINCT ACTIVATED PATHWAYS BETWEEN SUBGROUPS

Author

Forget, Antoine, primary, Loredana, Martignetti, additional, Brabetz, Sebastian, additional, Picard, Daniel, additional, Puget, Stephanie, additional, Calzone, Laurence, additional, Poullet, Patrick, additional, Montagud, Arnau, additional, Liva, Stephane, additional, Dingli, Florent, additional, Arras, Guillaume, additional, Yu, Hua, additional, Mercier, Audrey, additional, Pouponnot, Celio, additional, Loew, Damarys, additional, Bourdeaut, Franck, additional, Dufour, Christelle, additional, Varlet, Pascale, additional, Taylor, Michael, additional, Kool, Marcel, additional, Pfister, Stefan M, additional, Barillot, Emmanuel, additional, Remke, Marc, additional, and Olivier, Ayrault, additional

Published
2017
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