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1. Complex intracranial aneurysms: a DELPHI study to define associated characteristics

Author

Diana, Francesco, Romoli, Michele, Raz, Eytan, Agid, Ronit, Albuquerque, Felipe C., Arthur, Adam S., Beck, Jürgen, Berge, Jerome, Boogaarts, Hieronymus D., Burkhardt, Jan-Karl, Cenzato, Marco, Chapot, René, Charbel, Fady T., Desal, Hubert, Esposito, Giuseppe, Fifi, Johanna T., Florian, Stefan, Gruber, Andreas, Hassan, Ameer E., Jabbour, Pascal, Jadhav, Ashutosh P., Korja, Miikka, Krings, Timo, Lanzino, Giuseppe, Meling, Torstein R., Morcos, Jaques, Mosimann, Pascal J., Nossek, Erez, Pereira, Vitor Mendes, Raabe, Andreas, Regli, Luca, Rohde, Veit, Siddiqui, Adnan H., Tanikawa, Rokuya, Tjoumakaris, Stavropoula I., Tomasello, Alejandro, Vajkoczy, Peter, Valvassori, Luca, Velinov, Nikolay, Walsh, Daniel, Woo, Henry, Xu, Bin, Yoshimura, Shinichi, van Zwam, Wim H., and Peschillo, Simone

Published
2024
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3. How to iGuide: flat panel detector, CT-assisted, minimally invasive evacuation of intracranial hematomas.

Author

Dornbos Iii, David, Halabi, Cathra, DiNitto, Julie, Mueller, Kerstin, Fiorella, David, Cooke, Daniel L, and Arthur, Adam S

Subjects
Humans, Cerebral Hemorrhage, Hematoma, Tomography, X-Ray Computed, Treatment Outcome, Minimally Invasive Surgical Procedures, hemorrhage, technology, Biomedical Imaging, Bioengineering
Abstract

Evidence is growing to support minimally invasive surgical evacuation of intraparenchymal hematomas, particularly those with minimal residual hematoma volumes following evacuation. To maximize the potential for neurologic recovery, it is imperative that the trajectory for access to the hematoma minimizes disruption of normal parenchyma. Flat panel detector CT-based navigation and needle guidance software provides a platform that uses flat panel detector CT imaging obtained on the angiography table to aid reliable and safe access to the hematoma. In addition to providing a high degree of accuracy, this method also allows convenient and rapid re-imaging to assess navigation accuracy and the degree of hematoma evacuation prior to procedural completion. We provide a practical review of the syngo iGuide needle guidance software and the methodology for incorporating its use, and the software of other vendors, in a variety of minimally invasive methods for evacuation of intraparenchymal hematomas.

Published
2022

4. Pivotal trial of the Neuroform Atlas stent for treatment of posterior circulation aneurysms: one-year outcomes

Author

Jankowitz, Brian T, Jadhav, Ashutosh P, Gross, Bradley, Jovin, Tudor G, Alhajeri, Abdulnasser A, Fraser, Justin F, Hanel, Ricardo A, Sauvageau, Eric, Aghaebrahim, Amin, Frei, Donald, Bellon, Richard, Loy, David, Puri, Ajit S, Malek, Adel M, Thomas, Ajith, Toth, Gabor, Lopes, Demetrius Klee, Crowley, R Webster, Arthur, Adam S, Reavey-Cantwell, John, Lin, Eugene, Siddiqui, Adnan H, Alexander, Michael J, Khaldi, Ahmad, Colby, Geoffrey P, Caplan, Justin M, Satti, Sudhakar R, Turk, Aquilla S, Spiotta, Alejandro M, Klucznik, Richard, Hallam, Danial K, Kung, David, Froehler, Michael T, Callison, R Charles, Kan, Peter, Hetts, Steven W, and Zaidat, Osama O

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Bioengineering, Clinical Trials and Supportive Activities, Assistive Technology, Stroke, Neurosciences, Clinical Research, Aged, Cerebral Angiography, Embolization, Therapeutic, Female, Humans, Intracranial Aneurysm, Middle Aged, Prospective Studies, Retrospective Studies, Stents, Treatment Outcome, aneurysm, coil, stent, Clinical sciences
Abstract

BackgroundStent-assisted coiling of wide-necked intracranial aneurysms (IAs) using the Neuroform Atlas Stent System (Atlas) has shown promising results.ObjectiveTo present the primary efficacy and safety results of the ATLAS Investigational Device Exemption (IDE) trial in a cohort of patients with posterior circulation IAs.MethodsThe ATLAS trial is a prospective, multicenter, single-arm, open-label study of unruptured, wide-necked, IAs treated with the Atlas stent and adjunctive coiling. This study reports the results of patients with posterior circulation IAs. The primary efficacy endpoint was complete aneurysm occlusion (Raymond-Roy (RR) class I) on 12-month angiography, in the absence of re-treatment or parent artery stenosis >50%. The primary safety endpoint was any major ipsilateral stroke or neurological death within 12 months. Adjudication of the primary endpoints was performed by an imaging core laboratory and a Clinical Events Committee.ResultsThe ATLAS trial enrolled and treated 116 patients at 25 medical centers with unruptured, wide-necked, posterior circulation IAs (mean age 60.2±10.5 years, 81.0% (94/116) female). Stents were placed in all patients with 100% technical success rate. A total of 95/116 (81.9%) patients had complete angiographic follow-up at 12 months, of whom 81 (85.3%) had complete aneurysm occlusion (RR class I). The primary effectiveness outcome was achieved in 76.7% (95% CI 67.0% to 86.5%) of patients. Overall, major ipsilateral stroke and secondary persistent neurological deficit occurred in 4.3% (5/116) and 1.7% (2/116) of patients, respectively.ConclusionsIn the ATLAS IDE posterior circulation cohort, the Neuroform Atlas Stent System with adjunctive coiling demonstrated high rates of technical and safety performance. Trial registration number https://clinicaltrials.gov/ct2/show/NCT02340585.

Published
2022

5. Most Promising Approaches to Improve Brain AVM Management: ARISE I Consensus Recommendations

Author

Samaniego, Edgar A., Dabus, Guilherme, Meyers, Philip M., Kan, Peter T., Frösen, Juhana, Lanzino, Giuseppe, Welch, Babu G., Volovici, Victor, Gonzalez, Fernando, Fifi, Johana, Charbel, Fady T., Hoh, Brian L., Khalessi, Alexander, Marks, Michael P., Berenstein, Alejandro, Pereira, Victor M., Bain, Mark, Colby, Geoffrey P., Narayanan, Sandra, Tateshima, Satoshi, Siddiqui, Adnan H., Wakhloo, Ajay K., Arthur, Adam S., and Lawton, Michael T.

Published
2024
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10. Pivotal Trial of the Neuroform Atlas Stent for Treatment of Anterior Circulation Aneurysms

Author

Zaidat, Osama O, Hanel, Ricardo A, Sauvageau, Eric A, Aghaebrahim, Amin, Lin, Eugene, Jadhav, Ashutosh P, Jovin, Tudor G, Khaldi, Ahmad, Gupta, Rishi G, Johnson, Andrew, Frei, Donald, Loy, David, Malek, Adel, Toth, Gabor, Siddiqui, Adnan, Reavey-Cantwell, John, Thomas, Ajith, Hetts, Steven W, Jankowitz, Brian T, Gross, Bradley, Ducruet, Andrew, Panczkowski, David, Shoirah, Hazem, Al-Bayati, Alhamza, Weiner, Greg, Kenmuir, Cynthia, Tadi, Prasanna, Walker, Gregory, Johnson, K, Frei, Don, Bellon, Richard, Atchie, Benjamin, Kaminsky, Ian, Huddle, Dan, Bain, Mark, Rasmussen, Peter, Hussain, M Shazam, Moore, Nina, Masaryk, Thomas, Elgabaly, Mohamed, Cerejo, Russell, Hardman, Julian, John, Seby, Bauer, Andrew, Peih-Chir Tsai, Jenny, Levy, Elad, Snyder, Kenneth, Davies, Jason, Ogilvy, Christopher, Rivet, Dennis, Alexander, Michael, Moser, Franklin, Maya, Marcel, Schiraldi, Michael, Eboli, Paula, Caplan, Justin, Jiang, Bowen, Bender, Matthew, Colby, Geoffrey, Satti, Sudhakar, Sivapatham, Thinesh, Kung, David, Pukenas, Bryan, Hurst, Robert, Smith, Michelle J, Puri, Ajit, Massari, Francesco, Rex, David, Fraser, Justin, Grupke, Stephen, Alhajeri, Abdulnasser, Klucznik, Richard, Diaz, Orlando, Britz, Gavin, Zhan, Yi, Spiotta, Alejandro, Lena, Jonathan, Turk, Aquilla, Chaudry, Mohamad, Fargen, Kyle, Turner, Raymond, Kan, Peter, Duckworth, Edward, Asif Taqi, Muhammad, Hou, Samuel, Arthur, Adam S, Elijovich, Lucas, Hoit, Daniel, Nickele, Christopher, Vachhani, Jay, Thomas Doss, Vinodh, Crowley, Richard, Lopes, Demetrius, Chen, Michael, Hallam, Danial, Ghodke, Basavaraj, Kim, Louis, Callison, Richard, Alshekhlee, Amer, and Kale, Sushant

Subjects
Bioengineering, Stroke, Assistive Technology, Neurosciences, Clinical Research, Clinical Trials and Supportive Activities, Brain Disorders, Adult, Aged, Embolization, Therapeutic, Endovascular Procedures, Female, Humans, Intracranial Aneurysm, Male, Middle Aged, Stents, Treatment Outcome, angiography, intracranial aneurysm, middle cerebral artery, retreatment, stent, ATLAS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurology & Neurosurgery
Abstract

Background and purposeStent-assisted coil embolization using the new generation Neuroform Atlas Stent System has shown promising safety and efficacy. The primary study results of the anterior circulation aneurysm cohort of the treatment of wide-neck, saccular, intracranial, aneurysms with the Neuroform Atlas Stent System (ATLAS trial [Safety and Effectiveness of the Treatment of Wide Neck, Saccular Intracranial Aneurysms With the Neuroform Atlas Stent System]) are presented.MethodsATLAS IDE trial (Investigational Device Exemption) is a prospective, multicenter, single-arm, open-label study of wide-neck (neck ≥4 mm or dome-to-neck ratio 50%) at the target location. The primary safety end point was any major stroke or ipsilateral stroke or neurological death within 12 months. Adjudication of the primary end points was performed by an independent Imaging Core Laboratory and the Clinical Events Committee.ResultsA total of 182 patients with wide-neck anterior circulation aneurysms at 25 US centers were enrolled. The mean age was 60.3±11.4 years, 73.1% (133/182) women, and 80.8% (147/182) white. Mean aneurysm size was 6.1±2.2 mm, mean neck width was 4.1±1.2 mm, and mean dome-to-neck ratio was 1.2±0.3. The most frequent aneurysm locations were the anterior communicating artery (64/182, 35.2%), internal carotid artery ophthalmic artery segment (29/182, 15.9%), and middle cerebral artery bifurcation (27/182, 14.8%). Stents were placed in the anticipated anatomic location in all patients. The study met both primary safety and efficacy end points. The composite primary efficacy end point of complete aneurysm occlusion (Raymond-Roy 1) without parent artery stenosis or aneurysm retreatment was achieved in 84.7% (95% CI, 78.6%-90.9%) of patients. Overall, 4.4% (8/182, 95% CI, 1.9%-8.5%) of patients experienced a primary safety end point of major ipsilateral stroke or neurological death.ConclusionsIn the ATLAS IDE anterior circulation aneurysm cohort premarket approval study, the Neuroform Atlas stent with adjunctive coiling met the primary end points and demonstrated high rates of long-term complete aneurysm occlusion at 12 months, with 100% technical success and

Published
2020

12. Outcomes after endovascular mechanical thrombectomy for low compared to high National Institutes of Health Stroke Scale (NIHSS): A multicenter study

Author

Abecassis, Isaac Josh, Almallouhi, Eyad, Chalhoub, Reda, Kasab, Sami Al, Bass, Eric, Ding, Dale, Saini, Vasu, Burks, Joshua D., Maier, Ilko L., Psychogios, Marios-Nikos, Liman, Jan, Alawieh, Ali, Wolfe, Stacey, Arthur, Adam S., Shaban, Amir, Dumont, Travis, Kan, Peter, Kim, Joon-Tae, De Leacy, Reade, Osbun, Joshua, Rai, Ansaar, Jabbour, Pascal, Grossberg, Jonathan A., Park, Min S., Crosa, Roberto, Mascitelli, Justin, Levitt, Michael R., Polifka, Adam, Casagrande, Walter, Yoshimura, Shinichi, Matouk, Charles, Williamson, Richard W., Gory, Benjamin, Mokin, Maxim, Fragata, Isabel, Romano, Daniele G., Chowdhry, Shakeel A., Moss, Mark, Behme, Daniel, Limaye, Kaustubh, Spiotta, Alejandro M., and Starke, Robert M.

Published
2023
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16. Thrombectomy Techniques: Remote Aspiration

Author

Dornbos, David, III, Abuelem, Tarek, Fiorella, David J., Arthur, Adam S., Hui, Ferdinand K., editor, Spiotta, Alejandro M., editor, Alexander, Michael J., editor, Hanel, Ricardo A., editor, and Baxter, Blaise William, editor

Published
2021
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19. 214 Technical and Clinical Outcomes in Patients With Short-term Repeated Mechanical Thrombectomy: An International Multicenter Study

Author

Saad, Hassan, primary, Zohdy, Youssef M., additional, Howard, Brian M., additional, Cawley, C. Michael, additional, Pabaney, Aqueel Hussain, additional, Dimisko, Laurie, additional, Alawieh, Ali M., additional, Maier, Ilko, additional, Spiotta, Alejandro M., additional, Jabbour, Pascal, additional, Wolfe, Stacey Q., additional, Rai, Ansaar, additional, Kim, Joon-Tae, additional, Masitelli, Justin Robert, additional, Starke, Robert M., additional, Shaban, Amir, additional, Yoshimura, Shinichi, additional, De Leacy, Reade, additional, Kan, Peter T., additional, Fragata, Isabel, additional, Polifka, Adam J., additional, Arthur, Adam S., additional, Park, Min S., additional, Matouk, Charles, additional, Levitt, Michael Robert, additional, Tjoumarkaris, Stavropoula I., additional, Liman, Jan, additional, Fargen, Kyle Michael, additional, and Grossberg, Jonathan Andrew, additional

Published
2024
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22. Multicenter investigation of technical and clinical outcomes after thrombectomy for Proximal Medium Vessel Occlusion (pMeVO) by frontline technique.

Author

Grossberg, Jonathan A, Chalhoub, Reda M, Al Kasab, Sami, Pullmann, Dominika, Jabbour, Pascal, Psychogios, Marios, Starke, Robert M, Arthur, Adam S, Fargen, Kyle M, De Leacy, Reade, Kan, Peter, Dumont, Travis, Rai, Ansaar, Crosa, Roberto J, Naamani, Kareem E, Maier, Ilko, Goyal, Nitin, Wolfe, Stacey Quintero, Michael Cawley, C, and Mocco, J

Subjects
PROPENSITY score matching, ENDOVASCULAR surgery, TREATMENT effectiveness, STROKE, THROMBECTOMY
Abstract

Background: Endovascular thrombectomy(EVT) is the standard of care for large vessel occlusion(LVO) stroke. Data on technical and clinical outcome in proximal medium vessel occlusions(pMeVOs) comparing frontline techniques remain limited. Methods: We report an international multicenter retrospective study of patients undergoing EVT for stroke at 32 centers between 2015–2021. Patients were divided into LVOs(ICA/M1/Vertebrobasilar) or pMeVOs(M2/A1/P1) and categorized by thrombectomy technique. Primary outcome was 90-day good functional outcome(mRS ≤ 2). Multivariate logistic regressions were used to evaluate the impact of technical variables on clinical outcomes. Propensity score matching was used to compare outcome in patients with pMeVO treated with aspiration versus stent-retriever. Results: In the cohort of 5977 LVO and 1287 pMeVO patients, pMeVO did not independently predict good-outcome(p = 0.55). In pMeVO patients, successful recanalization irrespective of frontline technique(aOR = 3.2,p < 0.05), procedure time ≤ 1-h(aOR = 2.2,p < 0.05), and thrombectomy attempts ≤ 4(aOR = 2.8,p < 0.05) were independent predictors of good-outcomes. In a propensity-matched cohort of aspiration versus stent-retriever pMeVO patients, there was no difference in good-outcomes. The rates of hemorrhage were higher(9%vs.4%,p < 0.01) and procedure time longer(51-min vs. 33-min,p < 0.01) with stent-retriever, while the number of attempts was higher with aspiration(2.5vs.2,p < 0.01). Rates of hemorrhage and good-outcome showed an exponential relationship to procedural metrics, and were more dependent on time in the aspiration group compared to attempts in the stent-retriever group. Conclusions: Clinical outcomes following EVT for pMeVO are comparable to those in LVOs. The golden hour or 3-pass rules in LVO thrombectomy still apply to pMeVO thrombectomy. Different techniques may exhibit different futility metrics; SR thrombectomy was more influenced by attempts whereas aspiration was more dependent on procedure time. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Active drug-coated flow diverter in a preclinical model of intracranial stenting.

Author

King, Robert M., Peker, Ahmet, Epshtein, Mark, Arends, Jennifer M., Brochu, Alice B., Raskett, Christopher M., Slazas, Kimiko J., Puri, Ajit S., Arthur, Adam S., Fiorella, David, Gounis, Matthew J., and Anagnostakou, Vania

Subjects
PREVENTION of surgical complications, NEUROLOGIC examination, STATISTICAL correlation, BASILAR artery, T-test (Statistics), STATISTICAL significance, HEPARIN, OPTICAL coherence tomography, BRAIN, DOGS, MAGNETIC resonance imaging, MANN Whitney U Test, DESCRIPTIVE statistics, THROMBOEMBOLISM, ANIMAL experimentation, NEURORADIOLOGY, DATA analysis software, DRUG-eluting stents
Abstract

Background Flow diverters carry the risk of thromboembolic complications (TEC). We tested a coating with covalently bound heparin that activates antithrombin to address TEC by locally downregulating the coagulation cascade. We hypothesized that the neuroimaging evidence of TEC would be reduced by the coating. Methods 16 dogs were implanted with overlapping flow diverters in the basilar artery, separated into two groups: heparin-coated (n=9) and uncoated (n=7). Following implantation, high-frequency optical coherence tomography (HF-OCT) was acquired to quantify acute thrombus (AT) formation on the flow diverters. MRI was performed postoperatively and repeated at 1, 2, 3, 4, and 8 weeks, consisting of T1-weighted imaging, time-0f-flight (ToF), diffusion weighted imaging (DWI), susceptibility weighted imaging (SWI), and fluid attenuated inversion recovery (FLAIR) sequences. Neurological examinations were performed throughout the 8-week duration of the study. Results The mean AT volume on coated devices was lower than uncoated (0.014 vs 0.018 mm³); however, this was not significant (P=0.3). The mean number of foci of magnetic susceptibility artifacts (MSAs) on SWI was significantly different between the uncoated and coated groups at the 1-week follow-up (P<0.02), and remained statistically different throughout the duration of the study. The AT volume showed a direct linear correlation with the MSA count and 80% of the variance in the MSA could be explained by the AT volume (P<0.001). Pathological analysis showed evidence of ischemic injury at locations of MSA. Conclusions Heparin-coated flow diverters significantly reduced the number of new MSAs after 1 week follow-up, showing the potential to reduce TEC. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Refractory migraine: a cerebrovascular disease?

Author

Fiorella, David, Arthur, Adam S., Hsiangkuo Yuan, Bhogal, Pervinder, Goyal, Nitin, Khattar, Nicolas K., Albuquerque, Felipe C., Jadhav, Ashutosh P., Catapano, Joshua S., and Silberstein, Stephen

Subjects
THERAPEUTIC embolization, INTRAVENOUS therapy, CEREBROVASCULAR disease, MIGRAINE, MEDICAL care costs, DISEASE incidence, LIDOCAINE, MENINGEAL artery
Published
2024
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25. Blood Pressure Trajectories and Outcomes After Endovascular Thrombectomy for Acute Ischemic Stroke

Author

Katsanos, Aristeidis H., primary, Joundi, Raed A., additional, Palaiodimou, Lina, additional, Ahmed, Niaz, additional, Kim, Joon-Tae, additional, Goyal, Nitin, additional, Maier, Ilko L., additional, de Havenon, Adam, additional, Anadani, Mohammad, additional, Matusevicius, Marius, additional, Mistry, Eva A., additional, Khatri, Pooja, additional, Arthur, Adam S., additional, Sarraj, Amrou, additional, Yaghi, Shadi, additional, Shoamanesh, Ashkan, additional, Catanese, Luciana, additional, Psychogios, Marios-Nikos, additional, Tsioufis, Konstantinos, additional, Malhotra, Konark, additional, Spiotta, Alejandro M., additional, Sandset, Else Charlotte, additional, Alexandrov, Andrei V., additional, Petersen, Nils H., additional, and Tsivgoulis, Georgios, additional

Published
2024
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26. Abstract TP198: Factors Associated With Need for Decompressive Hemicraniectomy After Mechanical Thrombectomy in Stroke Patients

Author

Elawady, Sameh Samir, primary, Cunningham, Conor, additional, Matsukawa, Hidetoshi, additional, Uchida, Kazutaka, additional, Sowlat, Mohammad-Mahdi, additional, Lee Nawabi, Noah, additional, Zandpazandi, Sara, additional, Orscelik, Atakan, additional, Maier, Ilko, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Shaban, Amir, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian, additional, Alawieh, Ali M, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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27. Abstract WP215: Number of Passes Matter in Acute Ischemic Stroke Patients Who Underwent Failed Mechanical Thrombectomy

Author

Elawady, Sameh Samir, primary, Cunningham, Conor, additional, Matsukawa, Hidetoshi, additional, Sowlat, Mohammad-Mahdi, additional, Uchida, Kazutaka, additional, Zandpazandi, Sara, additional, Orscelik, Atakan, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Shaban, Amir, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian, additional, Alawieh, Ali M, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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28. Abstract TP187: Comparison of Balloon Guide Catheter versus Non-Balloon Guide Catheter for Mechanical Thrombectomy in Distal Medium Vessel Occlusion

Author

Orscelik, Atakan, primary, Kallmes, David F, additional, Bilgin, Cem, additional, Senol, Yigit Can, additional, Kobeissi, Hassan, additional, Elawady, Sameh Samir, additional, Cunningham, Conor, additional, Matsukawa, Hidetoshi, additional, Zandpazandi, Sara, additional, Sowlat, Mohammad-Mahdi, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian, additional, Alawieh, Ali, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, Brinjikji, Waleed, additional, and Spiotta, Alejandro M, additional

Published
2024
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29. Abstract WP184: Intravenous Thrombolysis Improves Outcomes in Stroke Patients With Unsuccessful Mechanical Thrombectomy

Author

Elawady, Sameh S, primary, Nawabi, Noah, additional, Matsukawa, Hidetoshi, additional, Cunningham, Conor, additional, Sowlat, Mohammad Mahdi, additional, Orscelik, Atakan, additional, Zandpazandi, Sara, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian, additional, Alawieh, Ali, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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30. Abstract TP197: Impact of First-Pass Effect on Clinical Outcomes in Stroke Patients With Low Aspects

Author

Elawady, Sameh S, primary, Sowlat, Mohammad Mahdi, additional, Matsukawa, Hidetoshi, additional, Cunningham, Conor, additional, Orscelik, Atakan, additional, Zandpazandi, Sara, additional, Al Kasab, Sami, additional, Maier, Ilko, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Wolfe, Stacey Q, additional, Rai, Ansaar, additional, Starke, Robert, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Grossberg, Jonathan A, additional, Alawieh, Ali, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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31. Abstract WP180: Novel Machine Learning Model for Prediction of Futile Recanalization in Acute Ischemic Stroke Patients With Anterior Circulation Large Vessel Occlusion

Author

Cunningham, Conor, primary, Zohdy, Youssef, additional, Elawady, Sameh Samir, additional, Matsukawa, Hidetoshi, additional, Sowlat, Mohammad-Mahdi, additional, Uchida, Kazutaka, additional, Zandpazandi, Sara, additional, Orscelik, Atakan, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian, additional, Alawieh, Ali M, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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32. Abstract TP193: Impact of Number of Passes on Outcomes of Mechanical Thrombectomy in Stroke Patients With Low ASPECTS

Author

Sowlat, Mohammad-Mahdi, primary, Elawady, Sameh S, additional, Matsukawa, Hidetoshi, additional, Cunningham, Conor, additional, Orscelik, Atakan, additional, Zandpazandi, Sara, additional, Lee Nawabi, Noah, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Grossberg, Jonathan A, additional, Alawieh, Ali, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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33. Abstract 153: First Pass Effect in Mechanical Thrombectomy for Anterior Circulation Acute Ischemic Stroke is Modified by Procedure Time: Proposal of a New Measure for Thrombectomy Procedures

Author

Koo, Andrew, primary, Reeves, Benjamin, additional, Renedo, Daniela, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Shaban, Amir, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Grossberg, Jonathan A, additional, Alawieh, Ali M, additional, Romano, Daniele, additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Park, Min, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, Spiotta, Alejandro M, additional, Sheth, Kevin N, additional, de Havenon, Adam H, additional, and Matouk, Charles C, additional

Published
2024
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35. Abstract TMP88: Impact of Tandem Vertebrobasilar Occlusion on Outcome of Mechanical Thrombectomy for Basilar Artery Occlusion

Author

Cunningham, Conor, primary, Elawady, Sameh Samir, additional, Matsukawa, Hidetoshi, additional, Lee Nawabi, Noah, additional, Sowlat, Mohammad-Mahdi, additional, Zandpazandi, Sara, additional, Uchida, Kazutaka, additional, Orscelik, Atakan, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal M, additional, Kim, Joon-Tae, additional, Quintero, Stacey C, additional, rai, ansaar, additional, Starke, Robert, additional, Psychogios, Marios, additional, Shaban, Amir, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Grossberg, Jonathan A, additional, Alawieh, Ali M, additional, Romano, Daniele G., additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles C, additional, Park, Min S, additional, Levitt, Michael, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade A, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2024
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37. Repeat thrombectomy after large vessel re-occlusion: a propensity score matched analysis of technical and clinical outcomes

Author

Zohdy, Youssef M, primary, Saad, Hassan, additional, Howard, Brian M, additional, Cawley, C Michael, additional, Pabaney, Aqueel, additional, Akbik, Feras, additional, Dimisko, Laurie, additional, Maier, Ilko, additional, Spiotta, Alejandro M, additional, Jabbour, Pascal, additional, Wolfe, Stacey Q, additional, Rai, Ansaar, additional, Kim, Joon-tae, additional, Mascitelli, Justin, additional, Starke, Robert M, additional, Shaban, Amir, additional, Yoshimura, Shinichi, additional, De Leacy, Reade, additional, Kan, Peter, additional, Fragata, Isabel, additional, Polifka, Adam J, additional, Arthur, Adam S, additional, Park, Min S, additional, Matouk, Charles, additional, Levitt, Michael R, additional, Tjoumakaris, Stavropoula I, additional, Liman, Jan, additional, Waiters, Vanesha, additional, Pradilla, Gustavo, additional, Fargen, Kyle M, additional, Alawieh, Ali, additional, and Grossberg, Jonathan A, additional

Published
2024
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38. Blood Pressure After Endovascular Thrombectomy and Outcomes in Patients With Acute Ischemic Stroke: An Individual Patient Data Meta-analysis

Author

Katsanos, Aristeidis H., Malhotra, Konark, Ahmed, Niaz, Seitidis, Georgios, Mistry, Eva A., Mavridis, Dimitris, Kim, Joon-Tae, Veroniki, Areti Angeliki, Maier, Ilko, Matusevicius, Marius, Khatri, Pooja, Anadani, Mohammad, Goyal, Nitin, Arthur, Adam S., Sarraj, Amrou, Yaghi, Shadi, Shoamanesh, Ashkan, Catanese, Luciana, Kantzanou, Maria, Psaltopoulou, Theodora, Rentzos, Alexandros, Psychogios, Marios, Van Adel, Brian, Spiotta, Alejandro M., Sandset, Else Charlotte, de Havenon, Adam, Alexandrov, Andrei V., Petersen, Nils H., and Tsivgoulis, Georgios

Published
2022
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40. The effects of stress hyperglycemia in diabetic and nondiabetic patients with large vessel occlusions undergoing mechanical thrombectomy.

Author

Kasturiarachi, Brittany M., Saeed, Omar, Gachechiladze, Leila, Alsbrook, Diana, Singh, Savdeep, Zaid, Ghaida, Eswaradass, Prasanna, Goyal, Nitin, Elangovan, Cheran, Arthur, Adam S., Alexandrov, Andrei V., and Krishnaiah, Balaji

Subjects
CEREBRAL infarction, ISCHEMIC stroke, COMPUTED tomography, BLOOD sugar, PEOPLE with diabetes, HYPERGLYCEMIA
Abstract

INTRODUCTION: Diabetes and hyperglycemia are major risk factors that can increase infarction volume and contribute to poor functional status. Our study aim was to investigate the effect of stress hyperglycemia on various safety and efficacy outcomes in patients with large vessel occlusions (LVOs) undergoing mechanical thrombectomy (MT) with or without diabetes. METHODS: A retrospective analysis of consecutive LVO patient data treated with MT at a Comprehensive Stroke Center in the Mid-South was conducted. Adult patients with LVO on computed tomography angiography (CTA) and treated with MT within 24 h of symptom onset were included. The primary outcome was to determine if there was an association in collateral flow or infarct size in the setting of hyperglycemia. Secondary outcomes included National Institute of Health Sciences Score (NIHSS) and Modified Rankin Score (mRS). RESULTS: A total of 450 patients underwent MT, out of which 433 had baseline hemoglobin A1c recorded: mean age: 64 ± 15 years, 47% women, pretreatment NIHSS median 15 points (interquartile range 10-19), 323 (75%) with good collaterals grades >2 on multiphasic CTA, 326 (75%) were non-diabetic, and 107 (25%) were diabetic. Nondiabetics with stress hyperglycemia had a tendency toward higher pre-treatment NIHSS scores (mean 17.5 ± 7.6, P = 0.02) and at 24-h (12.9 ± 9.0, P = 0.02), poor collaterals (multiphasic CTA score =2; 21.4% vs. 34.5%, P = 0.02), larger infarct volumes (50.7 ± 63.6 vs. 24.4 ± 33.8 cc, P < 0.0001), and had poorer functional outcomes (good mRS 0-2 47.7% vs. good mRS 0-2 36.8%) when compared to nondiabetics without stress hyperglycemia. For every 1 mg/dL increase in admission blood glucose, there was a 0.3 cc increase in infarct volume (95% confidence intervals for ß =0.2-0.4; P < 0.0001) after adjusting for the final thrombolysis in cerebral infarction score. CONCLUSIONS: LVO patients with stress hyperglycemia without previously diagnosed diabetes had more severe strokes, developed larger infarct volumes, poorer collaterals, and had worse functional outcomes at 90 days post-MT. In addition, LVO patients with diabetes and stress hyperglycemia exhibited more passes during MT and worse functional outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Triage of Emergent Large Vessel Occlusion (ELVO) patients directly to Comprehensive Stroke Centers (CSCs) is good practice and benefits patients in Urban and Suburban population Centers – New insights from the TRIAGE-STROKE and RACECAT studies

Author

Fiorella, David, primary, Jovin, Tudor G, additional, Arthur, Adam S, additional, Nogueira, Raul, additional, Siddiqui, Adnan H, additional, Hirsch, Joshua A, additional, and Albuquerque, Felipe C, additional

Published
2023
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42. Outcomes of mechanical thrombectomy in stroke patients with extreme large infarction core

Author

Almallouhi, Eyad, primary, Zandpazandi, Sara, additional, Anadani, Mohammad, additional, Cunningham, Conor, additional, Sowlat, Mohammad-Mahdi, additional, Matsukawa, Hidetoshi, additional, Orscelik, Atakan, additional, Elawady, Sameh Samir, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal, additional, Kim, Joon-tae, additional, Wolfe, Stacey Q, additional, Rai, Ansaar, additional, Starke, Robert M, additional, Psychogios, Marios-Nikos, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Grossberg, Jonathan A, additional, Alawieh, Ali, additional, Romano, Daniele G, additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam J, additional, Osbun, Joshua W, additional, Crosa, Roberto Javier, additional, Matouk, Charles, additional, Park, Min S, additional, Levitt, Michael R, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis M, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, and Spiotta, Alejandro M, additional

Published
2023
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43. Mechanical thrombectomy for the treatment of primary and secondary anterior cerebral artery occlusions: insights from STAR

Author

Dabhi, Nisha, primary, Kumar, Jeyan Sathia, additional, Ironside, Natasha, additional, Kellogg, Ryan T, additional, Sowlat, Mohammad-Mahdi, additional, Uchida, Kazutaka, additional, Maier, Ilko, additional, Al Kasab, Sami, additional, Jabbour, Pascal, additional, Kim, Joon-tae, additional, Wolfe, Stacey Q, additional, Rai, Ansaar, additional, Starke, Robert M, additional, Psychogios, Marios-Nikos, additional, Samaniego, Edgar A, additional, Arthur, Adam S, additional, Yoshimura, Shinichi, additional, Cuellar, Hugo, additional, Howard, Brian M, additional, Alawieh, Ali, additional, Romano, Daniele G, additional, Tanweer, Omar, additional, Mascitelli, Justin, additional, Fragata, Isabel, additional, Polifka, Adam J, additional, Osbun, Joshua W, additional, Crosa, Roberto Javier, additional, Matouk, Charles, additional, Levitt, Michael R, additional, Brinjikji, Waleed, additional, Moss, Mark, additional, Dumont, Travis M, additional, Williamson, Richard, additional, Navia, Pedro, additional, Kan, Peter, additional, De Leacy, Reade, additional, Chowdhry, Shakeel A, additional, Ezzeldin, Mohamad, additional, Spiotta, Alejandro M, additional, and Park, Min S, additional

Published
2023
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44. Refractory migraine: a cerebrovascular disease?

Author

Fiorella, David, primary, Arthur, Adam S, additional, Yuan, Hsiangkuo, additional, Bhogal, Pervinder, additional, Goyal, Nitin, additional, Khattar, Nicolas K, additional, Albuquerque, Felipe C, additional, Jadhav, Ashutosh P, additional, Catapano, Joshua S, additional, and Silberstein, Stephen, additional

Published
2023
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45. Comprehensive analysis of the impact of procedure time and the ‘golden hour’ in subpopulations of stroke thrombectomy patients

Author

Ash, Makenna, primary, Dimisko, Laurie, additional, Chalhoub, Reda M, additional, Howard, Brian M, additional, Cawley, C Michael, additional, Matouk, Charles, additional, Pabaney, Aqueel, additional, Spiotta, Alejandro M, additional, Jabbour, Pascal, additional, Maier, Ilko, additional, Wolfe, Stacey Q, additional, Rai, Ansaar T, additional, Kim, Joon-tae, additional, Psychogios, Marios-Nikos, additional, Mascitelli, Justin R, additional, Starke, Robert M, additional, Shaban, Amir, additional, Yoshimura, Shinichi, additional, De Leacy, Reade, additional, Kan, Peter, additional, Fragata, Isabel, additional, Polifka, Adam J, additional, Arthur, Adam S, additional, Park, Min S, additional, Crosa, Roberto Javier, additional, Williamson, Richard, additional, Dumont, Travis M, additional, Levitt, Michael R, additional, Al Kasab, Sami, additional, Tjoumakaris, Stavropoula I, additional, Liman, Jan, additional, Saad, Hassan, additional, Samaniego, Edgar A, additional, Fargen, Kyle M, additional, Grossberg, Jonathan A, additional, and Alawieh, Ali, additional

Published
2023
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47. The effect of occlusion location and technique in mechanical thrombectomy for minor stroke

Author

Abecassis, Isaac Josh, primary, Almallouhi, Eyad, additional, Chalhoub, Reda M., additional, Helal, Ahmed, additional, Naidugari, Janki R., additional, Kasab, Sami Al, additional, Bass, Eric, additional, Ding, Dale, additional, Saini, Vasu, additional, Burks, Joshua D., additional, Maier, Ilko L., additional, Jabbour, Pascal, additional, Kim, Joon-Tae, additional, Wolfe, Stacey, additional, Rai, Ansaar, additional, Psychogios, Marios-Nikos, additional, Samaniego, Edgar, additional, Arthur, Adam S., additional, Yoshimura, Shinichi, additional, Howard, Brian, additional, Alawieh, Ali, additional, Fragata, Isabel, additional, Cuellar, Hugo, additional, Polifka, Adam, additional, Mascitelli, Justin, additional, Osbun, Joshua, additional, Crosa, Roberto, additional, Matouk, Charles, additional, Park, Min S., additional, Levitt, Michael R., additional, Dumont, Travis, additional, Williamson, Richard W., additional, Spiotta, Alejandro M., additional, and Starke, Robert M., additional

Published
2023
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49. Association between blood pressure variability and outcomes after endovascular thrombectomy for acute ischemic stroke: An individual patient data meta-analysis.

Author

Palaiodimou, Lina, Joundi, Raed A, Katsanos, Aristeidis H, Ahmed, Niaz, Kim, Joon-Tae, Goyal, Nitin, Maier, Ilko L, de Havenon, Adam, Anadani, Mohammad, Matusevicius, Marius, Mistry, Eva A, Khatri, Pooja, Arthur, Adam S, Sarraj, Amrou, Yaghi, Shadi, Shoamanesh, Ashkan, Catanese, Luciana, Psychogios, Marios-Nikos, Malhotra, Konark, and Spiotta, Alejandro M

Published
2024
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50. Modified Orbitozygomatic Craniotomy, Anterior Clinoidectomy, and Retrograde Suction Decompression "Dallas Technique" for Large Unruptured Clinoidal-Ophthalmic Segment Aneurysm.

Author

Parikh, Kara A., Nguyen, Vincent N., Wu, Eva, Arthur, Adam S., Michael, L. Madison, and Khan, Nickalus R.

Subjects
CRANIOTOMY, ANEURYSMS, DECOMPRESSION (Physiology), SINUS of valsalva, LONGITUDINAL ligaments, ANTERIOR cerebral artery
Abstract

This article, published in the Journal of Neurological Surgery, describes a case study of a 60-year-old woman with a large unruptured clinoidal-ophthalmic segment aneurysm. The patient underwent a specific surgical procedure called the "Dallas Technique," which involved an orbitopterional craniotomy, anterior clinoidectomy, and retrograde suction decompression. The article provides technical details about the suction decompression technique used to treat giant paraclinoid aneurysms. The authors of the article are Kara A. Parikh, Vincent N. Nguyen, Eva Wu, Adam S. Arthur, L. Madison Michael, and Nickalus R. Khan. [Extracted from the article]

Published
2024
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