558 results on '"Chiba-Falek, Ornit"'
Search Results
2. Neuronal-type-specific epigenome editing to decrease SNCA expression: Implications for precision medicine in synucleinopathies
3. Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics.
4. Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
5. Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
6. Single-nucleus multi-omics of Parkinson's disease reveals a glutamatergic neuronal subtype susceptible to gene dysregulation via alteration of transcriptional networks.
7. Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
8. Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
9. Multi‐Omics Insights Into The Heterogeneity Of Depression In Alzheimer’s Disease
10. APOE‐targeted epigenome therapy for late onset Alzheimer’s disease
11. Integrative single‐nucleus multi‐omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains
12. Bioinformatics pipeline to guide post‐GWAS studies in Alzheimer’s: a new catalogue of disease candidate short structural variants
13. Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains
14. Lentiviral vectors as the delivery vehicles for transduction into iPSCs
15. Contributors
16. Bioinformatics strategy to advance the interpretation of Alzheimer's disease GWAS discoveries: The roads from association to causation
17. The APOE-TOMM40 Humanized Mouse Model: Characterization of Age, Sex, and PolyT Variant Effects on Gene Expression
18. Neurogenomics
19. Gene Expression
20. The effects of the TOMM40 poly-T alleles on Alzheimer's disease phenotypes
21. Shared genetic etiology underlying Alzheimer’s disease and major depressive disorder
22. Good problems to have? Policy and societal implications of a disease-modifying therapy for presymptomatic late-onset Alzheimer’s disease
23. Genetic analysis of α-synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies
24. Sex-specific effects of scavenger receptor class B type 1 (SR-BI) gene variants on serum lipid levels and hepatic gene expression
25. Expansion of the Parkinson disease-associated SNCA- Rep1 allele upregulates human α-synuclein in transgenic mouse brain
26. Expansion of the Parkinson disease-associated SNCA-Rep1 allele upregulates human alpha-synuclein in transgenic mouse brain.
27. Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimers disease brains
28. All-in-one AAV-delivered epigenome-editing platform:proof-of-conceptand therapeutic implications for neurodegenerative disorders
29. Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
30. Dissecting cell‐subtype specific regulatory variants and their target genes underpinning the pathogenesis of late onset Alzheimer’s disease
31. APOE ‐targeted epigenome therapy for late onset Alzheimer’s disease
32. Differential Gene Expression and DNA Methylation in the Risk of Depression in LOAD Patients
33. Clinical Trials of AD Delay of Onset: Enrichment by a Prognostic Genetic Biomarker
34. African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles
35. The cis-regulatory effect of an Alzheimer’s disease-associated poly-T locus on expression of TOMM40 and apolipoprotein E genes
36. Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
37. Infection and inflammation: New perspectives on Alzheimer's disease
38. Phenotypic regional functional imaging patterns during memory encoding in mild cognitive impairment and Alzheimer's disease
39. A homopolymer polymorphism in the TOMM40 gene contributes to cognitive performance in aging
40. Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer’s Disease Based on Major Depressive Disorder Risk Variants
41. Bioinformatics pipeline to guide late‐onset Alzheimer's disease (LOAD) post‐GWAS studies: Prioritizing transcription regulatory variants within LOAD‐associated regions
42. Bioinformatics pipeline to advance the identification of transcription regulatory variants in LOAD noncoding regions
43. Polygenic Risk Score Effectively Predicts Risk of Depression Onset in Alzheimer’s Disease
44. Faculty Opinions recommendation of Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease.
45. Chapter 4 - Lentiviral vectors as the delivery vehicles for transduction into iPSCs: shortcomings and benefits
46. Neurogenomics
47. Additional file 2 of Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains
48. Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection
49. Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains
50. Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer’s disease brains
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