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24,881 results on '"DOXYCYCLINE"'

1. Doxycycline with or without famciclovir for infectious ophthalmic and respiratory disease: a prospective, randomized, masked, placebo-controlled trial in 373 kittens

Author

Vernau, Karen M, Kim, Soohyun, Thomasy, Sara M, Lucyshyn, Danica R, Purpura, Jordyn, Montgomery, Elizabeth, Surmick, Jennifer D, Dubelko, Ariana R, Moussavi, Ardalan, Kass, Philip H, and Maggs, David J

Subjects
Veterinary Sciences, Agricultural, Veterinary and Food Sciences, Infectious Diseases, Clinical Trials and Supportive Activities, Clinical Research, Eye Disease and Disorders of Vision, 6.1 Pharmaceuticals, Eye, Good Health and Well Being, Animals, Cat Diseases, Cats, Respiratory Tract Infections, Doxycycline, Famciclovir, Anti-Bacterial Agents, Prospective Studies, Antiviral Agents, Male, Female, Drug Therapy, Combination, Treatment Outcome, Feline herpesvirus, antiviral medications, feline medicine, infectious disease, ophthalmology, pediatrics, Veterinary sciences
Abstract

ObjectivesThe aim of this study was to prospectively evaluate in a randomized, triple-masked, placebo-controlled trial, outcomes for kittens with ocular manifestations of infectious upper respiratory disease (IURD) treated with an ophthalmic and oral antibiotic only vs those also treated with famciclovir.MethodsKittens were stratified into three age (1 to

Published
2024

10. Effect of Antimicrobial Agent Coating on Physicochemical and Biologic Properties of Implant Abutments: A Systematic Review.

Author

de Campos, Murilo Rodrigues and Reis, Andréa Cândido dos

Subjects
DENTAL implants, MATERIALS testing, MEDICAL information storage & retrieval systems, DENTAL abutments, TETRACYCLINE, DENTAL materials, SURFACE properties, TITANIUM, PERI-implantitis, GLYCOPROTEINS, DOXYCYCLINE, STREPTOCOCCUS, ANTI-infective agents, PHYSICAL & theoretical chemistry, BIOMEDICAL materials, SYSTEMATIC reviews, MEDLINE, SILVER, HEALTH outcome assessment, ONLINE information services, METALS, QUALITY assurance, PROSTHESIS design & construction
Abstract

Purpose: To analyze the effectiveness of coating of abutments with antimicrobial agents and their influence on the physicochemical and biologic properties of the coated materials. Materials and Methods: This work was registered in Open Science Framework (osf.io/6tkcp) and followed the PRISMA protocols. A search of two independent reviewers of articles published up to October 29, 2021, was performed in the Embase, PubMed, Science Direct, and Scopus databases. Results: The databases found a total of 1,474 references. After excluding the duplicates, 1,050 remained. After reading the titles and abstracts and applying the inclusion criteria, 13 articles remained and were read in full. A total of 8 articles were included in this systematic review. Different antimicrobial agents have been used to coat abutments, including graphene oxide, polydopamine, titanium and zirconium nitride, lactoferrin, tetracycline, silver, and doxycycline with varied release times. Titanium-coated silver showed a better antimicrobial agent release time of up to 28 days. Chemical analysis confirmed the presence of antimicrobials on the surface after coating. Different pathogenic microorganisms, such as Streptococcus sanguinis, Streptococcus oralis, and Staphylococcus aureus, were inhibited when in contact with the coated surface. Conclusions: This review showed that there is still no consensus on which is the better antimicrobial agent and which coated materials have the better performance. However, the association of surface coating of abutments with antimicrobials is feasible and can benefit many patients, which can support their clinical use to favor the healing process and prevent infections that can lead to treatment failure with dental implants. [ABSTRACT FROM AUTHOR]

Published
2024
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