Author: "Delia, Mario" / Publication Year Range: Last 50 years - Searchworks@Jio Institute Digital Library Search Results

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1. Antiviral prophylaxis to prevent herpes simplex virus (HSV) and varicella zoster virus (VZV) reactivation in adult patients with newly diagnosed acute leukemia: results of a survey submitted to Italian centers belonging to SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group

Author: Forghieri, Fabio, Cordella, Stefano, Marchesi, Francesco, Itri, Federico, Del Principe, Maria Ilaria, Cavalieri, Elena, Pasciolla, Crescenza, Bonanni, Matteo, Criscuolo, Marianna, Fiorentini, Alessandro, Guolo, Fabio, Buquicchio, Caterina, Prezioso, Lucia, Delia, Mario, Melillo, Lorella, Audisio, Ernesta, Zannier, Maria Elena, Cerchione, Claudio, Dargenio, Michelina, Cattaneo, Chiara, Fracchiolla, Nicola Stefano, Pezone, Sara, Perruccio, Katia, Santoni, Adele, Candoni, Anna, Vignetti, Marco, Luppi, Mario, Pagano, Livio, and Busca, Alessandro
Published: 2024
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2. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from EPICOVIDEHA survey

Author: Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, da Silva, Maria Gomes, Glenthøj, Andreas, van Doesum, Jaap, Bilgin, Yavuz M, López-García, Alberto, Itri, Federico, Rodrigues, Raquel Nunes, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Venemyr, Caroline Berg, van Praet, Jens, Jaksic, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila-Valls, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Pinczés, László Imre, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola, Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José-Ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, di Blasi, Roberta, de Almedia, Joyce Marques, Dargenio, Michelina, Biernat, Monika M, Sciumè, Mariarita, de Ramón, Cristina, de Jonge, Nick, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenović, Miloš, Liévin, Raphaël, Hanáková, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, Cornely, Oliver A, Serrano, Laura, Susana, José-María Ribera-Santa, Meletiadis, Joseph, Tsirigotis, Panagiotis, Coppola, Nicola, Mikulska, Malgorzata, Erben, Nurettin, Besson, Caroline, Merelli, Maria, González-López, Tomás-José, Loureiro-Amigo, Jorge, García-Vidal, Carolina, de Kort, Elizabeth, Cuccaro, Annarosa, Zompi, Sofia, Reizine, Florian, Finizio, Olimpia, Duléry, Rémy, Calbacho, Maria, Abu-Zeinah, Ghaith, and Malak, Sandra
Subjects: Biotechnology, Emerging Infectious Diseases, Biodefense, Immunization, Infectious Diseases, Lung, Vaccine Related, Cancer, Prevention, Good Health and Well Being, Adult, Humans, COVID-19, SARS-CoV-2, COVID-19 Testing, Hematologic Neoplasms, Antibodies, Monoclonal, Antiviral Agents, Antibodies, Viral, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Paediatrics and Reproductive Medicine, Immunology
Abstract: Limited data are available on breakthrough COVID-19 in patients with hematologic malignancy (HM) after anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. Adult patients with HM, ≥1 dose of anti-SARS-CoV-2 vaccine, and breakthrough COVID-19 between January 2021 and March 2022 were analyzed. A total of 1548 cases were included, mainly lymphoid malignancies (1181 cases, 76%). After viral sequencing in 753 cases (49%), the Omicron variant was prevalent (517, 68.7%). Most of the patients received ≤2 vaccine doses before COVID-19 (1419, 91%), mostly mRNA-based (1377, 89%). Overall, 906 patients (59%) received COVID-19-specific treatment. After 30-day follow-up from COVID-19 diagnosis, 143 patients (9%) died. The mortality rate in patients with the Omicron variant was 7.9%, comparable to other variants, with a significantly lower 30-day mortality rate than in the prevaccine era (31%). In the univariable analysis, older age (P < .001), active HM (P < .001), and severe and critical COVID-19 (P = .007 and P < .001, respectively) were associated with mortality. Conversely, patients receiving monoclonal antibodies, even for severe or critical COVID-19, had a lower mortality rate (P < .001). In the multivariable model, older age, active disease, critical COVID-19, and 2-3 comorbidities were correlated with a higher mortality, whereas monoclonal antibody administration, alone (P < .001) or combined with antivirals (P = .009), was protective. Although mortality is significantly lower than in the prevaccination era, breakthrough COVID-19 in HM is still associated with considerable mortality. Death rate was lower in patients who received monoclonal antibodies, alone or in combination with antivirals.
Published: 2022

3. Decoding the historical tale: COVID-19 impact on haematological malignancy patients—EPICOVIDEHA insights from 2020 to 2022

Author: Martín-Vallejo, Francisco Javier, Zdziarski, Przemyslaw, Zarrinfer, Hossein, Wittig, Jana, Win, Sein, Wai-Man, Vivien, Víšek, Benjamín, Vinh, Donald C., Vehreschild, Maria, Varricchio, Gina, Tsirigotis, Panagiotis, Torres-Tienza, Ana, Tanase, Alina Daniela, Tafuri, Agostino, Stamouli, Maria, Sramek, Jiří, Soussain, Carole, Shirinova, Ayten, Schubert, Jörg, Schalk, Enrico, Salehi, Mohammad Reza, Saleh, Modar, Rosati, Giorgio, Roldán, Elisa, Reizine, Florian, Rêgo, Mayara, Regalado-Artamendi, Isabel, Popova, Marina, Pinto, Fernando, Philippe, Laure, Orth, Hans Martin, Ommen, Hans-Beier, Obr, Aleš, Núñez-Martín-Buitrago, Lucía, Noël, Nicolas, Neuhann, Julia, Nadali, Gianpaolo, Nacov, Julia A., Munhoz Alburquerque, Ana M., Mitra, Maria Enza, Mikulska, Malgorzata, Mellinghoff, Sibylle, Mechtel, Ben, Martín-González, Juan-Alberto, Malak, Sandra, Loureiro-Amigo, Jorge, Lorenzo De La Peña, Lisset, Liberti, Giulia, Landau, Marianne, Lacej, Ira, Kolditz, Martin, Kho, Chi Shan, Khedr, Reham Abdelaziz, Karthaus, Meinolf, Karlsson, Linda Katharina, Jiménez-Lorenzo, María-Josefa, Izuzquiza, Macarena, Hoell-Neugebauer, Baerbel, Herbrecht, Raoul, Heath, Christopher H., Guolo, Fabio, Grothe, Jan, Giordano, Antonio, Gerasymchuk, Sergey, García-Sanz, Ramón, García-Poutón, Nicole, Funke, Vaneuza Araújo Moreira, Fung, Monica, Flasshove, Charlotte, Fianchi, Luana, Essame, Jenna, Egger, Matthias, Drenou, Bernard, Dragonetti, Giulia, Desole, Maximilian, Della Pepa, Roberta, Deau Fischer, Bénédicte, De Kort, Elizabeth, De Cabo, Erik, Danion, François, Daguindau, Etienne, Cushion, Tania, Cremer, Louise, Criscuolo, Marianna, Cordini, Gregorio, Cingolani, Antonella, Ciceri, Fabio, Chowdhury, Fazle Rabbi, Chelysheva, Ekaterina, Chauchet, Adrien, Chai, Louis Yi Ann, Ceesay, M. Mansour, Busch, Elena, Brehon, Mathias, Borducchi, Davimar M.M., Booth, Stephen, Bologna, Serge, Berg Venemyr, Caroline, Bailén-Almorox, Rebeca, Antoniadou, Anastasia, Anastasopoulou, Amalia N., Altuntaş, Fevzi, Salmanton-García, Jon, Marchesi, Francesco, Farina, Francesca, Weinbergerová, Barbora, Itri, Federico, Dávila-Valls, Julio, Martín-Pérez, Sonia, Glenthøj, Andreas, Hersby, Ditte Stampe, Gomes Da Silva, Maria, Nunes Rodrigues, Raquel, López-García, Alberto, Córdoba, Raúl, Bilgin, Yavuz M., Falces-Romero, Iker, El-Ashwah, Shaimaa, Emarah, Ziad, Besson, Caroline, Kohn, Milena, Van Doesum, Jaap, Ammatuna, Emanuele, Marchetti, Monia, Labrador, Jorge, Zambrotta, Giovanni Paolo Maria, Verga, Luisa, Jaksic, Ozren, Nucci, Marcio, Piukovics, Klára, Cabirta-Touzón, Alba, Jiménez, Moraima, Arellano, Elena, Espigado, Ildefonso, Blennow, Ola, Nordlander, Anna, Meers, Stef, Vian Praet, Jens, Aiello, Tommaso Francesco, Garcia-Vidal, Carolina, Fracchiolla, Nicola S., Sciumè, Mariarita, Seval, Guldane Cengiz, Žák, Pavel, Buquicchio, Caterina, Tascini, Carlo, Gräfe, Stefanie K., Schönlein, Martin, Adžić-VUKIČEVIĆ, Tatjana, Bonuomo, Valentina, Cattaneo, Chiara, Nizamuddin, Summiya, Čerňan, Martin, Plantefeve, Gaëtan, Prin, Romane, Szotkovski, Tomas, Collins, Graham P., Dargenio, Michelina, Petzer, Verena, Wolf, Dominik, Čolović, Natasha, Prezioso, Lucia, Valković, Toni, Passamonti, Francesco, Méndez, Gustavo-Adolfo, Sili, Uluhan, Vena, Antonio, Bavastro, Martina, Limongelli, Alessandro, Duarte, Rafael F., Ledoux, Marie-Pierre, Cvetanoski, Milche, Stojanoski, Zlate, Machado, Marina, Batinić, Josip, Magliano, Gabriele, Biernat, Monika M., Pantić, Nikola, Poulsen, Christian Bjørn, Cuccaro, Annarosa, Del Principe, Maria Ilaria, Kulasekararaj, Austin, Ormazabal-Vélez, Irati, Busca, Alessandro, Demirkan, Fatih, Ijaz, Marriyam, Klimko, Nikolai, Stoma, Igor, Khostelidi, Sofya, Fernández, Noemí, Omrani, Ali S., Bergantim, Rui, De Jonge, Nick, Fouquet, Guillemette, Navrátil, Milan, Abu-Zeinah, Ghaith, Samarkos, Michail, Maertens, Johan, De Ramón, Cristina, Guidetti, Anna, Magyari, Ferenc, González-López, Tomás José, Lahmer, Tobias, Finizio, Olimpia, Ali, Natasha, Pinczés, László Imre, Lavilla-Rubira, Esperanza, Romano, Alessandra, Merelli, Maria, Delia, Mario, Calbacho, Maria, Meletiadis, Joseph, Antić, Darko, Hernández-Rivas, José-Ángel, Marques De Almeida, Joyce, Al-Khabori, Murtadha, Hoenigl, Martin, Tisi, Maria Chiara, Khanna, Nina, Barać, Aleksandra, Eisa, Noha, Di Blasi, Roberta, Liévin, Raphaël, Miranda-Castillo, Carolina, Bahr, Nathan C., Lamure, Sylvain, Papa, Mario Virgilio, Yahya, Ayel, Aujayeb, Avinash, Novák, Jan, Erben, Nurettin, Fernández-Galán, María, Ribera-Santa Susana, José-María, Rinaldi, Ikhwan, Fazzi, Rita, Piedimonte, Monica, Duléry, Rémy, Gonzaga, Yung, Soto-Silva, Andrés, Sapienza, Giuseppe, Serris, Alexandra, Drgoňa, Ľuboš, Groh, Ana, Serrano, Laura, Gavriilaki, Eleni, Tragiannidis, Athanasios, Prattes, Juergen, Coppola, Nicola, Otašević, Vladimir, Mladenović, Miloš, Mitrović, Mirjana, Mišković, Bojana, Jindra, Pavel, Zompi, Sofia, Sacchi, Maria Vittoria, Krekeler, Carolin, Shumilov, Evgenii, Infante, Maria Stefania, García-Bordallo, Daniel, Çolak, Gökçe Melis, Mayer, Jiří, Nygaard, Marietta, Hanáková, Michaela, Ráčil, Zdeněk, Quattrone, Martina, Bonanni, Matteo, Koehler, Philipp, Rahimli, Laman, Cornely, Oliver A., and Pagano, Livio
Published: 2024
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4. Multicenter retrospective analysis of clinical outcome of adult patients with mixed-phenotype acute leukemia treated with acute myeloid leukemia–like or acute lymphoblastic leukemia–like chemotherapy and impact of allogeneic stem cell transplantation: a Campus ALL study

Author: Lazzarotto, Davide, Tanasi, Ilaria, Vitale, Antonella, Piccini, Matteo, Dargenio, Michelina, Giglio, Fabio, Forghieri, Fabio, Fracchiolla, Nicola, Cerrano, Marco, Todisco, Elisabetta, Papayannidis, Cristina, Leoncin, Matteo, Defina, Marzia, Guolo, Fabio, Pasciolla, Crescenza, Delia, Mario, Chiusolo, Patrizia, Mulè, Antonino, Candoni, Anna, Bonifacio, Massimiliano, Pizzolo, Giovanni, and Foà, Robin
Published: 2023
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5. Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings

Author: MARQUES DE ALMEIDA, Joyce, HERNÁNDEZ-RIVAS, José-Ángel, GUIDETTI, Anna, FINIZIO, Olimpia, STOJANOSKI, Zlate, CVETANOSKI, Milche, MELETIADIS, Joseph, DE JONGE, Nick, ANTIĆ, Darko, ALI, Natasha, TISI, Maria Chiara, SERRANO, Laura, PLANTEFEVE, Gaëtan, KHANNA, Nina, HOENIGL, Martin, ČERŇAN, Martin, MIRANDA-CASTILLO, Carolina, FERNÁNDEZ-GALÁN, María, SERRIS, Alexandra, ERBEN, Nurettin, DULÉRY, Rémy, AUJAYEB, Avinash, PAPA, Mario Virgilio, NOVÁK, Jan, DELIA, Mario, SAPIENZA, Giuseppe, REIZINE, Florian, OMRANI, Ali S., DI BLASI, Roberta, LAMURE, Sylvain, DRGOŇA, Ľuboš, COPPOLA, Nicola, BATINIĆ, Josip, AL-KHABORI, Murtadha, RIBERA-SANTA SUSANA, José-María, PIEDIMONTE, Monica, LOUREIRO-AMIGO, Jorge, FOUQUET, Guillemette, FAZZI, Rita, DANION, François, SCHUBERT, Jörg, HOELL-NEUGEBAUER, Baerbel, BAHR, Nathan C., YAHIA, Ayel Omar, TORRES-ATIENZA, Ana, RINALDI, Ikhwan, POPOVA, Marina, OMMEN, Hans-Beier, MITRA, Maria Enza, MIKULSKA, Malgorzata, LACEJ, Ira, KHOSTELIDI, Sofya, WIN, Sein, VINH, Donald, SALEH, Modar, PRATTES, Juergen, JINDRA, Pavel, GUOLO, Fabio, DELLA PEPA, Roberta, CHELYSHEVA, Ekaterina, ZDZIARSKI, Przemyslaw, WAI-MAN, Vivien, SOTO-SILVA, Andrés, ORTH, Hans Martin, MALAK, Sandra, LORENZO DE LA PEÑA, Lisset, KOLDITZ, Martin, Shan KHO, Chi, HEATH, Christopher H., GROH, Ana, GAVRIILAKI, Eleni, FUNG, Monica, EGGER, Matthias, DE KORT, Elizabeth, DE CABO, Erik, CUSHION, Tania, CHOWDHURY, Fazle Rabbi, CEESAY, M. Mansour, BREHON, Mathias, VARRICCHIO, Gina, TAFURI, Agostino, JIMÉNEZ-LORENZO, María-Josefa, KLIMKO, Nikolai, TSIRIGOTIS, Panagiotis, ANTONIADOU, Anastasia, VEHRESCHILD, Maria, Rossi, Giuseppe, Salmanton-García, Jon, Cattaneo, Chiara, Marchesi, Francesco, Dávila-Valls, Julio, Martín-Pérez, Sonia, Itri, Federico, López-García, Alberto, Glenthøj, Andreas, Gomes da Silva, Maria, Besson, Caroline, Marchetti, Monia, Weinbergerová, Barbora, Jaksic, Ozren, Jiménez, Moraima, Bilgin, Yavuz M., Van Doesum, Jaap, Farina, Francesca, Žák, Pavel, Verga, Luisa, Collins, Graham P., Bonuomo, Valentina, Van Praet, Jens, Nucci, Marcio, Meers, Stef, Espigado, Ildefonso, Fracchiolla, Nicola S., Valković, Toni, Poulsen, Christian Bjørn, Čolović, Natasha, Dragonetti, Giulia, Ledoux, Marie-Pierre, Tascini, Carlo, Buquicchio, Caterina, Blennow, Ola, Passamonti, Francesco, Machado, Marina, Labrador, Jorge, Duarte, Rafael F., Schönlein, Martin, Prezioso, Lucia, Falces-Romero, Iker, Kulasekararaj, Austin, Garcia-Vidal, Carolina, Fernández, Noemí, Abu-Zeinah, Ghaith, Ormazabal-Vélez, Irati, Adžić-Vukičević, Tatjana, Piukovics, Klára, Stoma, Igor, Cuccaro, Annarosa, Magliano, Gabriele, Szotkowski, Tomáš, González-López, Tomás-José, El-Ashwah, Shaimaa, Bergantim, Rui, Sili, Uluhan, Maertens, Johan, Demirkan, Fatih, De Ramón, Cristina, Petzer, Verena, Del Principe, Maria Ilaria, Navrátil, Milan, Dargenio, Michelina, Seval, Guldane Cengiz, Samarkos, Michail, Ráčil, Zdeněk, Pinczés, László Imre, Lahmer, Tobias, Busca, Alessandro, Méndez, Gustavo-Adolfo, Vena, Antonio, Biernat, Monika M., Merelli, Maria, Calbacho, Maria, Barać, Aleksandra, Bavastro, Martina, Limongelli, Alessandro, Ilhan, Osman, Wolf, Dominik, Çolak, Gökçe Melis, García-Sanz, Ramón, Emarah, Ziad, Mišković, Bojana, Gräfe, Stefanie K., Mladenović, Miloš, Aiello, Tommaso Francesco, Núñez-Martín-Buitrago, Lucía, Nordlander, Anna, Arellano, Elena, Zambrotta, Giovanni Paolo Maria, Ammatuna, Emanuele, Cabirta, Alba, Sacchi, Maria Vittoria, Nunes Rodrigues, Raquel, Hersby, Ditte Stampe, Hanakova, Michaela, Rahimli, Laman, Cordoba, Raul, Cornely, Oliver A., and Pagano, Livio
Published: 2023
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6. Bloodstream infections due to Gram-negative bacteria in patients with hematologic malignancies: updated epidemiology and risk factors for multidrug-resistant strains in an Italian perspective survey

Author: Trecarichi, Enrico Maria, Giuliano, Gabriele, Cattaneo, Chiara, Ballanti, Stelvio, Criscuolo, Marianna, Candoni, Anna, Marchesi, Francesco, Laurino, Marica, Dargenio, Michelina, Fanci, Rosa, Cefalo, Mariagiovanna, Delia, Mario, Spolzino, Angelica, Maracci, Laura, Bonuomo, Valentina, Busca, Alessandro, Principe, Maria Ilaria Del, Daffini, Rosa, Simonetti, Edoardo, Dragonetti, Giulia, Zannier, Maria Elena, Pagano, Livio, and Tumbarello, Mario
Published: 2023
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7. Nirmatrelvir/ritonavir in COVID-19 patients with haematological malignancies: a report from the EPICOVIDEHA registry

Author: Piukovics, Klára, De Ramón, Cristina, Danion, François, Yahya, Ayel, Guidetti, Anna, Garcia-Vidal, Carolina, Sili, Uluhan, Meletiadis, Joseph, De Kort, Elizabeth, Verga, Luisa, Serrano, Laura, Erben, Nurettin, Di Blasi, Roberta, Tragiannidis, Athanasios, Ribera-Santa Susana, José-María, Ommen, Hans-Beier, Busca, Alessandro, Coppola, Nicola, Bergantim, Rui, Dragonetti, Giulia, Criscuolo, Marianna, Fianchi, Luana, Bonanni, Matteo, Soto-Silva, Andrés, Mikulska, Malgorzata, Machado, Marina, Shan Kho, Chi, Hassan, Nazia, Gavriilaki, Eleni, Cordini, Gregorio, Chi, Louis Yi Ann, Eggerer, Matthias, Hoenigl, Martin, Prattes, Juergen, Jiménez-Lorenzo, María-Josefa, Zompi, Sofia, Zambrotta, Giovanni Paolo Maria, Çolak, Gökçe Melis, García-Poutón, Nicole, Aiello, Tommaso Francesco, Prin, Romane, Stamouli, Maria, Samarkos, Michail, Salmanton-García, Jon, Marchesi, Francesco, Gomes da Silva, Maria, Farina, Francesca, Dávila-Valls, Julio, Bilgin, Yavuz M., Glenthøj, Andreas, Falces-Romero, Iker, Van Doesum, Jaap, Labrador, Jorge, Buquicchio, Caterina, El-Ashwah, Shaimaa, Petzer, Verena, Van Praet, Jens, Schönlein, Martin, Dargenio, Michelina, Méndez, Gustavo-Adolfo, Meers, Stef, Itri, Federico, Giordano, Antonio, Pinczés, László Imre, Espigado, Ildefonso, Stojanoski, Zlate, López-García, Alberto, Prezioso, Lucia, Jaksic, Ozren, Vena, Antonio, Fracchiolla, Nicola S., González-López, Tomás José, Colović, Natasa, Delia, Mario, Weinbergerová, Barbora, Marchetti, Monia, Marques de Almeida, Joyce, Finizio, Olimpia, Besson, Caroline, Biernat, Monika M., Valković, Toni, Lahmer, Tobias, Cuccaro, Annarosa, Ormazabal-Vélez, Irati, Batinić, Josip, Fernández, Noemí, De Jonge, Nick, Tascini, Carlo, Anastasopoulou, Amalia N., Duléry, Rémy, Del Principe, Maria Ilaria, Plantefeve, Gaëtan, Papa, Mario Virgilio, Nucci, Marcio, Jiménez, Moraima, Aujayeb, Avinash, Hernández-Rivas, José-Ángel, Merelli, Maria, Cattaneo, Chiara, Blennow, Ola, Nordlander, Anna, Cabirta, Alba, Varricchio, Gina, Sacchi, Maria Vittoria, Cordoba, Raul, Arellano, Elena, Gräfe, Stefanie K., Wolf, Dominik, Emarah, Ziad, Ammatuna, Emanuele, Hersby, Ditte Stampe, Martín-Pérez, Sonia, Nunes Rodrigues, Raquel, Rahimli, Laman, Pagano, Livio, and Cornely, Oliver A.
Published: 2023
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8. MOLNUPIRAVIR COMPARED TO NIRMATRELVIR/RITONAVIR FOR COVID-19 IN HIGH-RISK PATIENTS WITH HAEMATOLOGICAL MALIGNANCY IN EUROPE. A MATCHED-PAIRED ANALYSIS FROM THE EPICOVIDEHA REGISTRY

Author: SALMANTON-GARCÍA, Jon, MARCHESI, Francesco, KOEHLER, Philipp, WEINBERGEROVÁ, Barbora, ČOLOVIĆ, Natasa, FALCES-ROMERO, Iker, BUQUICCHIO, Caterina, FARINA, Francesca, PRAET, Jens VAN, BIERNAT, Monika M., ITRI, Federico, PREZIOSO, Lucia, TASCINI, Carlo, VENA, Antonio, ROMANO, Alessandra, DELIA, Mario, DÁVILA-VALLS, Julio, MARTÍN-PÉREZ, Sonia, LAVILLA-RUBIRA, Esperanza, ADŽIĆ-VUKIČEVIĆ, Tatjana, GARCÍA-BORDALLO, Daniel, LÓPEZ-GARCÍA, Alberto, CRISCUOLO, Mariana, PETZER, Verena, FRACCHIOLLA, Nicola S., ESPIGADO, Ildefonso, SILI, Uluhan, MEERS, Stef, ERBEN, Nurettin, CATTANEO, Chiara, TRAGIANNIDIS, Athanasios, GAVRIILAKI, Eleni, SCHÖNLEIN, Martin, MITROVIC, Mirjana, PANTIC, Nikola, MERELLI, Maria, LABRADOR, Jorge, HERNÁNDEZ-RIVAS, José-Ángel, GLENTHØJ, Andreas, FOUQUET, Guillemette, DEL PRINCIPE, Maria Ilaria, DARGENIO, Michelina, CALBACHO, María, BESSON, Caroline, KOHN, Milena, GRÄFE, Stefanie, HERSBY, Ditte Stampe, ARELLANO, Elena, MelisÇOLAK, Gökçe, WOLF, Dominik, MARCHETTI, Monia, NORDLANDER, Anna, BLENNOW, Ola, CORDOBA, Raul, MIŠKOVIĆ, Bojana, MLADENOVIĆ, Miloš, BAVASTRO, Martina, LIMONGELLI, Alessandro, RAHIMLI, Laman, PAGANO, Livio, and CORNELY, Oliver A.
Published: 2023
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9. Decoding the historical tale: COVID-19 impact on haematological malignancy patients—EPICOVIDEHA insights from 2020 to 2022

Author: Salmanton-García, Jon, primary, Marchesi, Francesco, additional, Farina, Francesca, additional, Weinbergerová, Barbora, additional, Itri, Federico, additional, Dávila-Valls, Julio, additional, Martín-Pérez, Sonia, additional, Glenthøj, Andreas, additional, Hersby, Ditte Stampe, additional, Gomes Da Silva, Maria, additional, Nunes Rodrigues, Raquel, additional, López-García, Alberto, additional, Córdoba, Raúl, additional, Bilgin, Yavuz M., additional, Falces-Romero, Iker, additional, El-Ashwah, Shaimaa, additional, Emarah, Ziad, additional, Besson, Caroline, additional, Kohn, Milena, additional, Van Doesum, Jaap, additional, Ammatuna, Emanuele, additional, Marchetti, Monia, additional, Labrador, Jorge, additional, Zambrotta, Giovanni Paolo Maria, additional, Verga, Luisa, additional, Jaksic, Ozren, additional, Nucci, Marcio, additional, Piukovics, Klára, additional, Cabirta-Touzón, Alba, additional, Jiménez, Moraima, additional, Arellano, Elena, additional, Espigado, Ildefonso, additional, Blennow, Ola, additional, Nordlander, Anna, additional, Meers, Stef, additional, Vian Praet, Jens, additional, Aiello, Tommaso Francesco, additional, Garcia-Vidal, Carolina, additional, Fracchiolla, Nicola S., additional, Sciumè, Mariarita, additional, Seval, Guldane Cengiz, additional, Žák, Pavel, additional, Buquicchio, Caterina, additional, Tascini, Carlo, additional, Gräfe, Stefanie K., additional, Schönlein, Martin, additional, Adžić-VUKIČEVIĆ, Tatjana, additional, Bonuomo, Valentina, additional, Cattaneo, Chiara, additional, Nizamuddin, Summiya, additional, Čerňan, Martin, additional, Plantefeve, Gaëtan, additional, Prin, Romane, additional, Szotkovski, Tomas, additional, Collins, Graham P., additional, Dargenio, Michelina, additional, Petzer, Verena, additional, Wolf, Dominik, additional, Čolović, Natasha, additional, Prezioso, Lucia, additional, Valković, Toni, additional, Passamonti, Francesco, additional, Méndez, Gustavo-Adolfo, additional, Sili, Uluhan, additional, Vena, Antonio, additional, Bavastro, Martina, additional, Limongelli, Alessandro, additional, Duarte, Rafael F., additional, Ledoux, Marie-Pierre, additional, Cvetanoski, Milche, additional, Stojanoski, Zlate, additional, Machado, Marina, additional, Batinić, Josip, additional, Magliano, Gabriele, additional, Biernat, Monika M., additional, Pantić, Nikola, additional, Poulsen, Christian Bjørn, additional, Cuccaro, Annarosa, additional, Del Principe, Maria Ilaria, additional, Kulasekararaj, Austin, additional, Ormazabal-Vélez, Irati, additional, Busca, Alessandro, additional, Demirkan, Fatih, additional, Ijaz, Marriyam, additional, Klimko, Nikolai, additional, Stoma, Igor, additional, Khostelidi, Sofya, additional, Fernández, Noemí, additional, Omrani, Ali S., additional, Bergantim, Rui, additional, De Jonge, Nick, additional, Fouquet, Guillemette, additional, Navrátil, Milan, additional, Abu-Zeinah, Ghaith, additional, Samarkos, Michail, additional, Maertens, Johan, additional, De Ramón, Cristina, additional, Guidetti, Anna, additional, Magyari, Ferenc, additional, González-López, Tomás José, additional, Lahmer, Tobias, additional, Finizio, Olimpia, additional, Ali, Natasha, additional, Pinczés, László Imre, additional, Lavilla-Rubira, Esperanza, additional, Romano, Alessandra, additional, Merelli, Maria, additional, Delia, Mario, additional, Calbacho, Maria, additional, Meletiadis, Joseph, additional, Antić, Darko, additional, Hernández-Rivas, José-Ángel, additional, Marques De Almeida, Joyce, additional, Al-Khabori, Murtadha, additional, Hoenigl, Martin, additional, Tisi, Maria Chiara, additional, Khanna, Nina, additional, Barać, Aleksandra, additional, Eisa, Noha, additional, Di Blasi, Roberta, additional, Liévin, Raphaël, additional, Miranda-Castillo, Carolina, additional, Bahr, Nathan C., additional, Lamure, Sylvain, additional, Papa, Mario Virgilio, additional, Yahya, Ayel, additional, Aujayeb, Avinash, additional, Novák, Jan, additional, Erben, Nurettin, additional, Fernández-Galán, María, additional, Ribera-Santa Susana, José-María, additional, Rinaldi, Ikhwan, additional, Fazzi, Rita, additional, Piedimonte, Monica, additional, Duléry, Rémy, additional, Gonzaga, Yung, additional, Soto-Silva, Andrés, additional, Sapienza, Giuseppe, additional, Serris, Alexandra, additional, Drgoňa, Ľuboš, additional, Groh, Ana, additional, Serrano, Laura, additional, Gavriilaki, Eleni, additional, Tragiannidis, Athanasios, additional, Prattes, Juergen, additional, Coppola, Nicola, additional, Otašević, Vladimir, additional, Mladenović, Miloš, additional, Mitrović, Mirjana, additional, Mišković, Bojana, additional, Jindra, Pavel, additional, Zompi, Sofia, additional, Sacchi, Maria Vittoria, additional, Krekeler, Carolin, additional, Shumilov, Evgenii, additional, Infante, Maria Stefania, additional, García-Bordallo, Daniel, additional, Çolak, Gökçe Melis, additional, Cingolani, Antonella, additional, Mayer, Jiří, additional, Criscuolo, Marianna, additional, Nygaard, Marietta, additional, Hanáková, Michaela, additional, Fianchi, Luana, additional, Ráčil, Zdeněk, additional, Giordano, Antonio, additional, Quattrone, Martina, additional, Bonanni, Matteo, additional, Koehler, Philipp, additional, Rahimli, Laman, additional, Cornely, Oliver A., additional, Pagano, Livio, additional, Martín-Vallejo, Francisco Javier, additional, Zdziarski, Przemyslaw, additional, Zarrinfer, Hossein, additional, Wittig, Jana, additional, Win, Sein, additional, Wai-Man, Vivien, additional, Víšek, Benjamín, additional, Vinh, Donald C., additional, Vehreschild, Maria, additional, Varricchio, Gina, additional, Tsirigotis, Panagiotis, additional, Torres-Tienza, Ana, additional, Tanase, Alina Daniela, additional, Tafuri, Agostino, additional, Stamouli, Maria, additional, Sramek, Jiří, additional, Soussain, Carole, additional, Shirinova, Ayten, additional, Schubert, Jörg, additional, Schalk, Enrico, additional, Salehi, Mohammad Reza, additional, Saleh, Modar, additional, Rosati, Giorgio, additional, Roldán, Elisa, additional, Reizine, Florian, additional, Rêgo, Mayara, additional, Regalado-Artamendi, Isabel, additional, Popova, Marina, additional, Pinto, Fernando, additional, Philippe, Laure, additional, Orth, Hans Martin, additional, Ommen, Hans-Beier, additional, Obr, Aleš, additional, Núñez-Martín-Buitrago, Lucía, additional, Noël, Nicolas, additional, Neuhann, Julia, additional, Nadali, Gianpaolo, additional, Nacov, Julia A., additional, Munhoz Alburquerque, Ana M., additional, Mitra, Maria Enza, additional, Mikulska, Malgorzata, additional, Mellinghoff, Sibylle, additional, Mechtel, Ben, additional, Martín-González, Juan-Alberto, additional, Malak, Sandra, additional, Loureiro-Amigo, Jorge, additional, Lorenzo De La Peña, Lisset, additional, Liberti, Giulia, additional, Landau, Marianne, additional, Lacej, Ira, additional, Kolditz, Martin, additional, Kho, Chi Shan, additional, Khedr, Reham Abdelaziz, additional, Karthaus, Meinolf, additional, Karlsson, Linda Katharina, additional, Jiménez-Lorenzo, María-Josefa, additional, Izuzquiza, Macarena, additional, Hoell-Neugebauer, Baerbel, additional, Herbrecht, Raoul, additional, Heath, Christopher H., additional, Guolo, Fabio, additional, Grothe, Jan, additional, Gerasymchuk, Sergey, additional, García-Sanz, Ramón, additional, García-Poutón, Nicole, additional, Funke, Vaneuza Araújo Moreira, additional, Fung, Monica, additional, Flasshove, Charlotte, additional, Essame, Jenna, additional, Egger, Matthias, additional, Drenou, Bernard, additional, Dragonetti, Giulia, additional, Desole, Maximilian, additional, Della Pepa, Roberta, additional, Deau Fischer, Bénédicte, additional, De Kort, Elizabeth, additional, De Cabo, Erik, additional, Danion, François, additional, Daguindau, Etienne, additional, Cushion, Tania, additional, Cremer, Louise, additional, Cordini, Gregorio, additional, Ciceri, Fabio, additional, Chowdhury, Fazle Rabbi, additional, Chelysheva, Ekaterina, additional, Chauchet, Adrien, additional, Chai, Louis Yi Ann, additional, Ceesay, M. Mansour, additional, Busch, Elena, additional, Brehon, Mathias, additional, Borducchi, Davimar M.M., additional, Booth, Stephen, additional, Bologna, Serge, additional, Berg Venemyr, Caroline, additional, Bailén-Almorox, Rebeca, additional, Antoniadou, Anastasia, additional, Anastasopoulou, Amalia N., additional, and Altuntaş, Fevzi, additional
Published: 2024
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10. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from the EPICOVIDEHA survey

Author: Serrano, Laura, Ribera-Santa Susana, José-María, Meletiadis, Joseph, Tsirigotis, Panagiotis, Coppola, Nicola, Mikulska, Malgorzata, Erben, Nurettin, Besson, Caroline, Merelli, Maria, González-López, Tomás-José, Loureiro-Amigo, Jorge, García-Vidal, Carolina, Kort, Elizabeth de, Cuccaro, Annarosa, Zompi, Sofia, Reizine, Florian, Finizio, Olimpia, Duléry, Rémy, Calbacho, Maria, Abu-Zeinah, Ghaith, Malak, Sandra, Zdziarski, Przemyslaw, Varrichio, Gina, Tragiannidis, Athanasios, Plantefeve, Gaëtan, Duarte, Rafael, Danion, François, Tisi, Maria Chiara, Sakellari, Ioanna, Karthaus, Meinholf, Groh, Ana, Fung, Monica, Emarah, Ziad, Coronel-Ayala, Omar-Francisco, Ann Chai, Louis Yi, Brehon, Mathias, Bonuomo, Valentina, Wolf, Dominik, Wittig, Jana, Vehreschild, Maria, Papa, Mario Virgilio, Neuhann, Julia, Jiménez-Lorenzo, María-Josefa, Grothe, Jan, Gavriilaki, Eleni, García-Sanz, Ramón, García-Poutón, Nicole, El-Ashwah, Shaimaa Saber, Eggerer, Matthias, Cordoba, Raul, Çolak, Gökçe Melis, Arellano, Elena, Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, Gomes da Silva, Maria, Glenthøj, Andreas, van Doesum, Jaap, Bilgin, Yavuz M., López-García, Alberto, Itri, Federico, Nunes Rodrigues, Raquel, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, van Praet, Jens, Jaksic, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila-Valls, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Imre Pinczés, László, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola, Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José-Ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, di Blasi, Roberta, Marques de Almedia, Joyce, Dargenio, Michelina, Biernat, Monika M., Sciumè, Mariarita, de Ramón, Cristina, de Jonge, Nick, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenović, Miloš, Liévin, Raphaël, Hanáková, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, and Cornely, Oliver A.
Published: 2022
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11. Considerations on antimicrobial prophylaxis in patients with lymphoproliferative diseases: A SEIFEM group position paper

Author: Busca, Alessandro, Cattaneo, Chiara, De Carolis, Elena, Nadali, Gianpaolo, Offidani, Massimo, Picardi, Marco, Candoni, Anna, Ceresoli, Eleonora, Criscuolo, Marianna, Delia, Mario, Della Pepa, Roberta, Del Principe, Ilaria, Fanci, Roma. Rosa, Farina, Francesca, Fracchiolla, Nicola, Giordano, Claudia, Malagola, Michele, Marchesi, Francesco, Piedimonte, Monica, Prezioso, Lucia, Quinto, Angela Maria, Spolzino, Angelica, Tisi, Maria Chiara, Trastulli, Fabio, Trecarichi, Enrico Maria, Zappasodi, Patrizia, Tumbarello, Mario, and Pagano, Livio
Published: 2021
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12. Decoding the historical tale: COVID-19 impact on haematological malignancy patients-EPICOVIDEHA insights from 2020 to 2022

Author: Arellano-Orden, Elena [0000-0003-0581-8947], Salmanton-García, Jon, Marchesi, Francesco, Farina, Francesca, Weinbergerová, Barbora, Itri, Federico, Dávila-Valls, Julio, Martín-Pérez, Sonia, Glenthøj, Andreas, Hersby, Ditte Stampe, Gomes da Silva, Maria, Nunes Rodrigues, Raquel, López-García, Alberto, Córdoba, Raúl, Bilgin, Yavuz M., Falces-Romero, Iker, El-Ashwah, Shaimaa, Emarah, Ziad, Besson, Caroline, Kohn, Milena, Van Doesum, Jaap, Ammatuna, Emanuele, Marchetti, Monia, Labrador, Jorge, Zambrotta, Giovanni Paolo Maria, Verga, Luisa, Jaksic, Ozren, Nucci, Marcio, Piukovics, Klára, Cabirta-Touzón, Alba, Jiménez, Moraima, Arellano-Orden, Elena, Espigado, Ildefonso, Blennow, Ola, Nordlander, Anna, Meers, Stef, van Praet, Jens, Aiello, Tommaso Francesco, Garcia-Vidal, Carolina, Fracchiolla, Nicola, Sciumè, Mariarita, Seval, Guldane Cengiz, Žák, Pavel, Buquicchio, Caterina, Tascini, Carlo, Gräfe, Stefanie K., Schönlein, Martin, Adžić-Vukičević, Tatjana, Bonuomo, Valentina, Cattaneo, Chiara, Nizamuddin, Summiya, Čerňan, Martin, Plantefeve, Gaëtan, Prin, Romane, Szotkovski, Tomas, Collins, Graham P., Dargenio, Michelina, Petzer, Verena, Wolf, Dominik, Čolović, Natasha, Prezioso, Lucia, Valković, Toni, Passamonti, Francesco, Méndez, Gustavo-Adolfo, Sili, Uluhan, Vena, Antonio, Bavastro, Martina, Limongelli, Alessandro, Duarte, Rafael F., Ledoux, Marie-Pierre, Cvetanoski, Milche, Stojanoski, Zlate, Machado, Marina, Batinić, Josip, Magliano, Gabriele, Biernat, Monika M., Pantić, Nikola, Poulsen, Christian Bjørn, Cuccaro, Annarosa, Del Principe, Maria Ilaria, Kulasekararaj, Austin, Ormazabal-Vélez, Irati, Busca, Alessandro, Demirkan, Fatih, Ijaz, Marriyam, Klimko, Nikolai, Stoma, Igor, Khostelidi, Sofya, Fernández, Noemí, Omrani, Ali S, Bergantim, Rui, De Jonge, Nick, Fouquet, Guillemette, Navrátil, Milan, Abu-Zeinah, Ghaith, Samarkos, Michail, Maertens, Johan, De Ramón, Cristina, Guidetti, Anna, Magyari, Ferenc, González-López, Tomás José, Lahmer, Tobias, Finizio, Olimpia, Ali, Natasha, Pinczés, László Imre, Lavilla-Rubira, Esperanza, Romano, Alessandra, Merelli, Maria, Delia, Mario, Calbacho, Maria, Meletiadis, Joseph, Antić, Darko, Hernández-Rivas, José-Ángel, Marques de Almeida, Joyce, Al-Khabori, Murtadha, Hoenigl, Martin, Tisi, Maria Chiara, Khanna, Nina, Barać, Aleksandra, Eisa, Noha, Di Blasi, Roberta, Liévin, Raphaël, Miranda-Castillo, Carolina, Bahr, Nathan C., Lamure, Sylvain, Papa, Mario Virgilio, Yahya, Ayel, Aujayeb, Avinash, Novák, Jan, Erben, Nurettin, Fernández-Galán, María, Ribera-Santa Susana, José-María, Rinaldi, Ikhwan, Fazzi, Rita, Piedimonte, Monica, Duléry, Rémy, Gonzaga, Yung, Soto-Silva, Andrés, Sapienza, Giuseppe, Serris, Alexandra, Drgoňa, Ľuboš, Groh, Ana, Serrano, Laura, Gavriilaki, Eleni, Tragiannidis, Athanasios, Prattes, Juergen, Coppola, Nicola, Otašević, Vladimir, Mladenović, Miloš, Mitrović, Mirjana, Mišković, Bojana, Jindra, Pavel, Zompi, Sofia, Sacchi, Maria Vittoria, Krekeler, Carolin, Infante, Maria Stefania, García-Bordallo, Daniel, Çolak, Gökçe Melis, Mayer, Jiří, Nygaard, Marietta, Hanáková, Michaela, Ráčil, Zdeněk, Bonanni, Matteo, Koehler, Philipp, Rahimli, Laman, Cornely, Oliver A., Pagano, Livio, Arellano-Orden, Elena [0000-0003-0581-8947], Salmanton-García, Jon, Marchesi, Francesco, Farina, Francesca, Weinbergerová, Barbora, Itri, Federico, Dávila-Valls, Julio, Martín-Pérez, Sonia, Glenthøj, Andreas, Hersby, Ditte Stampe, Gomes da Silva, Maria, Nunes Rodrigues, Raquel, López-García, Alberto, Córdoba, Raúl, Bilgin, Yavuz M., Falces-Romero, Iker, El-Ashwah, Shaimaa, Emarah, Ziad, Besson, Caroline, Kohn, Milena, Van Doesum, Jaap, Ammatuna, Emanuele, Marchetti, Monia, Labrador, Jorge, Zambrotta, Giovanni Paolo Maria, Verga, Luisa, Jaksic, Ozren, Nucci, Marcio, Piukovics, Klára, Cabirta-Touzón, Alba, Jiménez, Moraima, Arellano-Orden, Elena, Espigado, Ildefonso, Blennow, Ola, Nordlander, Anna, Meers, Stef, van Praet, Jens, Aiello, Tommaso Francesco, Garcia-Vidal, Carolina, Fracchiolla, Nicola, Sciumè, Mariarita, Seval, Guldane Cengiz, Žák, Pavel, Buquicchio, Caterina, Tascini, Carlo, Gräfe, Stefanie K., Schönlein, Martin, Adžić-Vukičević, Tatjana, Bonuomo, Valentina, Cattaneo, Chiara, Nizamuddin, Summiya, Čerňan, Martin, Plantefeve, Gaëtan, Prin, Romane, Szotkovski, Tomas, Collins, Graham P., Dargenio, Michelina, Petzer, Verena, Wolf, Dominik, Čolović, Natasha, Prezioso, Lucia, Valković, Toni, Passamonti, Francesco, Méndez, Gustavo-Adolfo, Sili, Uluhan, Vena, Antonio, Bavastro, Martina, Limongelli, Alessandro, Duarte, Rafael F., Ledoux, Marie-Pierre, Cvetanoski, Milche, Stojanoski, Zlate, Machado, Marina, Batinić, Josip, Magliano, Gabriele, Biernat, Monika M., Pantić, Nikola, Poulsen, Christian Bjørn, Cuccaro, Annarosa, Del Principe, Maria Ilaria, Kulasekararaj, Austin, Ormazabal-Vélez, Irati, Busca, Alessandro, Demirkan, Fatih, Ijaz, Marriyam, Klimko, Nikolai, Stoma, Igor, Khostelidi, Sofya, Fernández, Noemí, Omrani, Ali S, Bergantim, Rui, De Jonge, Nick, Fouquet, Guillemette, Navrátil, Milan, Abu-Zeinah, Ghaith, Samarkos, Michail, Maertens, Johan, De Ramón, Cristina, Guidetti, Anna, Magyari, Ferenc, González-López, Tomás José, Lahmer, Tobias, Finizio, Olimpia, Ali, Natasha, Pinczés, László Imre, Lavilla-Rubira, Esperanza, Romano, Alessandra, Merelli, Maria, Delia, Mario, Calbacho, Maria, Meletiadis, Joseph, Antić, Darko, Hernández-Rivas, José-Ángel, Marques de Almeida, Joyce, Al-Khabori, Murtadha, Hoenigl, Martin, Tisi, Maria Chiara, Khanna, Nina, Barać, Aleksandra, Eisa, Noha, Di Blasi, Roberta, Liévin, Raphaël, Miranda-Castillo, Carolina, Bahr, Nathan C., Lamure, Sylvain, Papa, Mario Virgilio, Yahya, Ayel, Aujayeb, Avinash, Novák, Jan, Erben, Nurettin, Fernández-Galán, María, Ribera-Santa Susana, José-María, Rinaldi, Ikhwan, Fazzi, Rita, Piedimonte, Monica, Duléry, Rémy, Gonzaga, Yung, Soto-Silva, Andrés, Sapienza, Giuseppe, Serris, Alexandra, Drgoňa, Ľuboš, Groh, Ana, Serrano, Laura, Gavriilaki, Eleni, Tragiannidis, Athanasios, Prattes, Juergen, Coppola, Nicola, Otašević, Vladimir, Mladenović, Miloš, Mitrović, Mirjana, Mišković, Bojana, Jindra, Pavel, Zompi, Sofia, Sacchi, Maria Vittoria, Krekeler, Carolin, Infante, Maria Stefania, García-Bordallo, Daniel, Çolak, Gökçe Melis, Mayer, Jiří, Nygaard, Marietta, Hanáková, Michaela, Ráčil, Zdeněk, Bonanni, Matteo, Koehler, Philipp, Rahimli, Laman, Cornely, Oliver A., and Pagano, Livio
Abstract: The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. While interventions like vaccines, targeted antivirals, and monoclonal antibodies have been effective for the general population, their benefits for these patients may not be as pronounced.
Published: 2024

13. Infection control in patients with myelodysplastic syndromes who are candidates for active treatment: Expert panel consensus-based recommendations

Author: Girmenia, Corrado, Candoni, Anna, Delia, Mario, Latagliata, Roberto, Molteni, Alfredo, Oliva, Esther N., Palumbo, Giuseppe A., Poloni, Antonella, Salutari, Prassede, Santini, Valeria, Voso, Maria Teresa, and Musto, Pellegrino
Published: 2019
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14. P487: MIDOSTAURIN PLASMA EXPOSURE IN PATIENTS WITH FLT3-MUT ACUTE MYELOID LEUKEMIA UNDERGOING POSACONAZOLE PROPHYLAXIS DURING INDUCTION TREATMENT: A PROSPECTIVE MULTICENTRE STUDY FROM THE SEIFEM GROUP

Author: Marchesi, Francesco, primary, Menna, Pierantonio, additional, Cattaneo, Chiara, additional, Candoni, Anna, additional, Delia, Mario, additional, Nadali, Gianpaolo, additional, Pasciolla, Crescenza, additional, Perrone, Salvatore, additional, Verga, Luisa, additional, Armiento, Daniele, additional, Ilaria DEL Principe, Maria, additional, Stefano Fracchiolla, Nicola, additional, Salvatorelli, Emanuela, additional, Lupisella, S, additional, Terrenato, Irene, additional, Busca, Alessandro, additional, and Pagano, Livio, additional
Published: 2023
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15. S292: NIRMATRELVIR/RITONAVIR IN COVID-19 PATIENTS WITH HAEMATOLOGICAL MALIGNANCIES: A REPORT FROMTHE EPICOVIDEHA REGISTRY

Author: Salmanton-García, Jon, primary, Marchesi, Francesco, additional, Gomes Da Silva, Maria, additional, Farina, Francesca, additional, Dávila-Valls, Julio, additional, Bilgin, Yavuz M., additional, Glenthøj, Andreas, additional, Falces-Romero, Iker, additional, Van Doesum, Jaap, additional, Labrador, Jorge, additional, Buquicchio, Caterina, additional, EL-Ashwah, Shaimaa, additional, Petzer, Verena, additional, VAN Praet, Jens, additional, Schönlein, Martin, additional, Dargenio, Michelina, additional, Méndez, Gustavo-Adolfo, additional, Meers, Stef, additional, Itri, Federico, additional, Giordano, Antonio, additional, Imre Pinczes, Laszlo, additional, Espigado, Ildefonso, additional, Stojanoski, Zlate, additional, Lopez-Garcia, Alberto, additional, Prezioso, Lucia, additional, Jaksic, Ozren, additional, Vena, Antonio, additional, Stefano Fracchiolla, Nicola, additional, Jose Gonzalez-Lopez, Tomas, additional, Čolović, Natasa, additional, Delia, Mario, additional, Weinbergerová, Barbora, additional, Marchetti, Monia, additional, Marques DE Almeida, Joyce, additional, Finizio, Olimpia, additional, Besson, Caroline, additional, Biernat, Monika M., additional, Valkovic, Toni, additional, Lahmer, Tobias, additional, Cuccaro, Annarosa, additional, Ormazabal Velez, Irati, additional, Batinic, Josip, additional, Fernández, Noemí, additional, de Jonge, Nick, additional, Tascini, Carlo, additional, Anastasopoulou, Amalia N., additional, Duléry, Rémy, additional, Ilaria DEL Principe, Maria, additional, Plantefeve, Gaëtan, additional, Virgilio Papa, Mario, additional, Nucci, Marcio, additional, Carmen Jimenez Balarezo, Moraima, additional, Aujayeb, Avinash, additional, Angel Hernandez Rivas, Jose, additional, Merelli, Maria, additional, Cattaneo, Chiara, additional, Blennow, Ola, additional, Nordlander, Anna, additional, Cabirta, Alba, additional, Varricchio, Gina, additional, Vittoria Sacchi, Maria, additional, Cordoba, Raul, additional, Arellano, Elena, additional, Gräfe, Stefanie, additional, Wolf, Dominik, additional, Emarah, Ziad, additional, Ammatuna, Emanuele, additional, Stampe Hersby, Ditte, additional, Martín-Pérez, Sonia, additional, Nunes Rodrigues, Raquel, additional, Rahimli, Laman, additional, Pagano, Livio, additional, and Cornely, Oliver A., additional
Published: 2023
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16. Brentuximab vedotin prior to allogeneic stem cell transplantation increases survival in chemorefractory Hodgkin’s lymphoma patients

Author: Gaudio, Francesco, Mazza, Patrizio, Mele, Anna, Palazzo, Giulia, Carella, Angelo Michele, Delia, Mario, Pisapia, Giovanni, Pastore, Domenico, Cascavilla, Nicola, Pavone, Vincenzo, and Specchia, Giorgina
Published: 2019
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17. FLAG-Ida Regimen as Bridge Therapy to Allotransplantation in Refractory/Relapsed Acute Myeloid Leukemia Patients

Author: Delia, Mario, Pastore, Domenico, Carluccio, Paola, Pasciolla, Crescenza, Ricco, Alessandra, Rossi, Antonella Russo, Casieri, Paola, Mestice, Anna, Albano, Francesco, and Specchia, Giorgina
Published: 2017
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18. Posaconazole and midostaurin in patients with FLT3‐mutated acute myeloid leukemia: Pharmacokinetic interactions and clinical facts in a real life study

Author: Menna, Pierantonio, primary, Marchesi, Francesco, additional, Cattaneo, Chiara, additional, Candoni, Anna, additional, Delia, Mario, additional, Nadali, Gianpaolo, additional, Vatteroni, Alessandra, additional, Pasciolla, Crescenza, additional, Perrone, Salvatore, additional, Verga, Luisa, additional, Armiento, Daniele, additional, Del Principe, Maria Ilaria, additional, Fracchiolla, Nicola S., additional, Salvatorelli, Emanuela, additional, Lupisella, Santina, additional, Terrenato, Irene, additional, Busca, Alessandro, additional, Minotti, Giorgio, additional, and Pagano, Livio, additional
Published: 2023
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19. Multicenter Observational Retrospective Study on Febrile Events in Patients with Acute Myeloid Leukemia Treated with Cpx-351 in “Real-Life”: The SEIFEM Experience

Author: Fianchi, Luana, primary, Guolo, Fabio, additional, Marchesi, Francesco, additional, Cattaneo, Chiara, additional, Gottardi, Michele, additional, Restuccia, Francesco, additional, Candoni, Anna, additional, Ortu La Barbera, Elettra, additional, Fazzi, Rita, additional, Pasciolla, Crescenza, additional, Finizio, Olimpia, additional, Fracchiolla, Nicola, additional, Delia, Mario, additional, Lessi, Federica, additional, Dargenio, Michelina, additional, Bonuomo, Valentina, additional, Del Principe, Maria Ilaria, additional, Zappasodi, Patrizia, additional, Picardi, Marco, additional, Basilico, Claudia, additional, Piedimonte, Monica, additional, Minetto, Paola, additional, Giordano, Antonio, additional, Chiusolo, Patrizia, additional, Prezioso, Lucia, additional, Buquicchio, Caterina, additional, Melillo, Lorella Maria Antonia, additional, Zama, Daniele, additional, Farina, Francesca, additional, Mancini, Valentina, additional, Terrenato, Irene, additional, Rondoni, Michela, additional, Urbino, Irene, additional, Tumbarello, Mario, additional, Busca, Alessandro, additional, and Pagano, Livio, additional
Published: 2023
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20. The Impact of Graft CD3 Cell/Regulatory T Cell Ratio on Acute Graft-versus-Host Disease and Post-Transplantation Outcome: A Prospective Multicenter Study of Patients with Acute Leukemia Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

Author: Delia, Mario, Carluccio, Paola, Mestice, Anna, Chiusolo, Patrizia, Metafuni, Elisabetta, Bellesi, Silvia, Arpinati, Mario, Milone, Giulio Antonio, Martino, Massimo, Mazza, Patrizio, Ingrosso, Claudia, Vacca, Adriana, Saporiti, Giorgia, Zallio, Francesco, Attolico, Immacolata, Pastore, Domenico, Specchia, Giorgina, Albano, Francesco, and Musto, Pellegrino
Published: 2021
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21. Blinatumomab differentially modulates peripheral blood and bone marrow immune cell repertoire: A Campus ALL study.

Author: Ocadlikova, Darina, Lussana, Federico, Fracchiolla, Nicola, Bonifacio, Massimiliano, Santoro, Lidia, Delia, Mario, Chiaretti, Sabina, Pasciolla, Crescenza, Cignetti, Alessandro, Forghieri, Fabio, Grimaldi, Francesco, Corradi, Giulia, Zannoni, Letizia, De Propris, Stefania, Borleri, Gian Maria, Tanasi, Ilaria, Vadakekolathu, Jayakumar, Rutella, Sergio, Guarini, Anna Rita, and Foà, Robin
Subjects: BONE marrow cells, REGULATORY T cells, LYMPHOBLASTIC leukemia, KILLER cells, IMMUNE checkpoint proteins
Abstract: Summary: Blinatumomab is the first bi‐specific T‐cell engager approved for relapsed or refractory B‐cell precursor acute lymphoblastic leukaemia (B‐ALL). Despite remarkable clinical results, the effects of blinatumomab on the host immune cell repertoire are not fully elucidated. In the present study, we characterized the peripheral blood (PB) and, for the first time, the bone marrow (BM) immune cell repertoire upon blinatumomab treatment. Twenty‐nine patients with B‐ALL received blinatumomab according to clinical practice. Deep multiparametric flow cytometry was used to characterize lymphoid subsets during the first treatment cycle. Blinatumomab induced a transient redistribution of PB effector T‐cell subsets and Treg cells with a persistent increase in cytotoxic NK cells, which was associated with a transient upregulation of immune checkpoint receptors on PB CD4 and CD8 T‐cell subpopulations and of CD39 expression on suppressive Treg cells. Of note, BM immune T‐cell subsets showed a broader post‐treatment subversion, including the modulation of markers associated with a T‐cell‐exhausted phenotype. In conclusion, our study indicates that blinatumomab differentially modulates the PB and BM immune cell repertoire, which may have relevant clinical implications in the therapeutic setting. [ABSTRACT FROM AUTHOR]
Published: 2023
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22. Long-Lasting Protective Effect of Posaconazole Prophylaxis in Patients with Acute Myeloid Leukemia Receiving Allogeneic Hematopoietic Stem Cell Transplantation

Author: Busca, Alessandro, Candoni, Anna, Audisio, Ernesta, Passera, Roberto, Bruno, Benedetto, Monaco, Federico, Mordini, Nicola, Vacca, Adriana, Delia, Mario, Aversa, Franco, and Pagano, Livio
Published: 2016
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23. Febrile events in acute lymphoblastic leukemia: a prospective observational multicentric SEIFEM study (SEIFEM-2012/B ALL)

Author: Di Blasi, Roberta, Cattaneo, Chiara, Lewis, Russell E., Tumbarello, Mario, Angelici, Laura, Dragonetti, Giulia, Busca, Alessandro, Cambò, Benedetta, Candoni, Anna, Cesarini, Monica, Cesaro, Simone, Delia, Mario, Fanci, Rosa, Farina, Francesca, Garzia, Mariagrazia, Giordano, Antonio, Martino, Bruno, Melillo, Lorella, Nadali, Gianpaolo, Perriello, Vincenzo, Picardi, Marco, Quinto, Angela Maria, Salutari, Prassede, Spolzino, Angelica, Vacca, Adriana, Vetro, Calogero, Zancanella, Michelle, Nosari, Annamaria, Aversa, Franco, Pagano, Livio, and on the behalf of the SEIFEM group (Sorveglianza Epidemiologica Infezioni Fungine in Ematologia)
Published: 2018
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24. Comparable survival using a CMV-matched or a mismatched donor for CMV+ patients undergoing T-replete haplo-HSCT with PT-Cy for acute leukemia: a study of behalf of the infectious diseases and acute leukemia working parties of the EBMT

Author: Cesaro, Simone, Crocchiolo, Roberto, Tridello, Gloria, Knelange, Nina, Van Lint, Maria Teresa, Koc, Yener, Ciceri, Fabio, Gülbas, Zafer, Tischer, Johanna, Afanasyev, Boris, Bruno, Benedetto, Castagna, Luca, Blaise, Didier, Mohty, Mohamad, Irrera, Giuseppe, Diez-Martin, J. L., Pierelli, Luca, Pioltelli, Pietro, Arat, Mutlu, Delia, Mario, Fagioli, Franca, Ehninger, Gerhard, Aljurf, Mahmoud, Carella, Angelo Michele, Ozdogu, Hakan, Mikulska, Malgorzata, Ljungman, Per, Nagler, Arnon, and Styczynski, Jan
Published: 2018
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25. Nirmatrelvir/ritonavir in COVID-19 patients with haematological malignancies: a report from the EPICOVIDEHA registry

Author: Salmanton-García, Jon, primary, Marchesi, Francesco, additional, Gomes da Silva, Maria, additional, Farina, Francesca, additional, Dávila-Valls, Julio, additional, Bilgin, Yavuz M., additional, Glenthøj, Andreas, additional, Falces-Romero, Iker, additional, Van Doesum, Jaap, additional, Labrador, Jorge, additional, Buquicchio, Caterina, additional, El-Ashwah, Shaimaa, additional, Petzer, Verena, additional, Van Praet, Jens, additional, Schönlein, Martin, additional, Dargenio, Michelina, additional, Méndez, Gustavo-Adolfo, additional, Meers, Stef, additional, Itri, Federico, additional, Giordano, Antonio, additional, Pinczés, László Imre, additional, Espigado, Ildefonso, additional, Stojanoski, Zlate, additional, López-García, Alberto, additional, Prezioso, Lucia, additional, Jaksic, Ozren, additional, Vena, Antonio, additional, Fracchiolla, Nicola S., additional, González-López, Tomás José, additional, Colović, Natasa, additional, Delia, Mario, additional, Weinbergerová, Barbora, additional, Marchetti, Monia, additional, Marques de Almeida, Joyce, additional, Finizio, Olimpia, additional, Besson, Caroline, additional, Biernat, Monika M., additional, Valković, Toni, additional, Lahmer, Tobias, additional, Cuccaro, Annarosa, additional, Ormazabal-Vélez, Irati, additional, Batinić, Josip, additional, Fernández, Noemí, additional, De Jonge, Nick, additional, Tascini, Carlo, additional, Anastasopoulou, Amalia N., additional, Duléry, Rémy, additional, Del Principe, Maria Ilaria, additional, Plantefeve, Gaëtan, additional, Papa, Mario Virgilio, additional, Nucci, Marcio, additional, Jiménez, Moraima, additional, Aujayeb, Avinash, additional, Hernández-Rivas, José-Ángel, additional, Merelli, Maria, additional, Cattaneo, Chiara, additional, Blennow, Ola, additional, Nordlander, Anna, additional, Cabirta, Alba, additional, Varricchio, Gina, additional, Sacchi, Maria Vittoria, additional, Cordoba, Raul, additional, Arellano, Elena, additional, Gräfe, Stefanie K., additional, Wolf, Dominik, additional, Emarah, Ziad, additional, Ammatuna, Emanuele, additional, Hersby, Ditte Stampe, additional, Martín-Pérez, Sonia, additional, Nunes Rodrigues, Raquel, additional, Rahimli, Laman, additional, Pagano, Livio, additional, Cornely, Oliver A., additional, Piukovics, Klára, additional, De Ramón, Cristina, additional, Danion, François, additional, Yahya, Ayel, additional, Guidetti, Anna, additional, Garcia-Vidal, Carolina, additional, Sili, Uluhan, additional, Meletiadis, Joseph, additional, De Kort, Elizabeth, additional, Verga, Luisa, additional, Serrano, Laura, additional, Erben, Nurettin, additional, Di Blasi, Roberta, additional, Tragiannidis, Athanasios, additional, Ribera-Santa Susana, José-María, additional, Ommen, Hans-Beier, additional, Busca, Alessandro, additional, Coppola, Nicola, additional, Bergantim, Rui, additional, Dragonetti, Giulia, additional, Criscuolo, Marianna, additional, Fianchi, Luana, additional, Bonanni, Matteo, additional, Soto-Silva, Andrés, additional, Mikulska, Malgorzata, additional, Machado, Marina, additional, Shan Kho, Chi, additional, Hassan, Nazia, additional, Gavriilaki, Eleni, additional, Cordini, Gregorio, additional, Chi, Louis Yi Ann, additional, Eggerer, Matthias, additional, Hoenigl, Martin, additional, Prattes, Juergen, additional, Jiménez-Lorenzo, María-Josefa, additional, Zompi, Sofia, additional, Zambrotta, Giovanni Paolo Maria, additional, Çolak, Gökçe Melis, additional, García-Poutón, Nicole, additional, Aiello, Tommaso Francesco, additional, Prin, Romane, additional, Stamouli, Maria, additional, and Samarkos, Michail, additional
Published: 2023
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26. Long term follow-up of refractory/relapsed acute myeloid leukemia patients treated with the FLAG-Ida regimen as bridge therapy to allotransplantation: 10-year results from a single centre experience.

Author: Delia, Mario, primary, Gagliardi, Vito Pier, additional, Carluccio, Paola, additional, Attolico, Immacolata, additional, Contento, Corinne, additional, Di Gennaro, Daniela, additional, Albano, Francesco, additional, and Musto, Pellegrino, additional
Published: 2023
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27. Clinical features and prognostic factors of Magnusiomyces (Saprochaete) infections in haematology. A multicentre study of SEIFEM/Fungiscope

Author: Del Principe, Maria Ilaria, Seidel, Danila, Criscuolo, Marianna, Dargenio, Michelina, Racil, Zdenek, Piedimonte, Monica, Marchesi, Francesco, Nadali, Gianpaolo, Koehler, Philipp, Fracchiolla, Nicola, Cattaneo, Chiara, Klimko, Nikolai, Spolzino, Angelica, Karapinar, Deniz Yilmaz, Demiraslan, Hayati, Duarte, Rafael F., Demeter, Judit, Stanzani, Marta, Melillo, Lorella Maria Antonia, Basilico, Claudia Maria, Cesaro, Simone, Paterno, Giovangiacinto, Califano, Catello, Delia, Mario, Buzzatti, Elisa, Busca, Alessandro, Cornely, Oliver A., Pagano, Livio, Alakel, Nael, Arsenijevi'c, Valentina Arsi'c, Camus, Vincent, Falces-Romero, Iker, Itzhak, Levy, Kouba, Michal, Martino, Rodrigo, Sedlacek, Petr, Weinbergerova, Barbora, Del Principe, Maria Ilaria, Seidel, Danila, Criscuolo, Marianna, Dargenio, Michelina, Racil, Zdenek, Piedimonte, Monica, Marchesi, Francesco, Nadali, Gianpaolo, Koehler, Philipp, Fracchiolla, Nicola, Cattaneo, Chiara, Klimko, Nikolai, Spolzino, Angelica, Karapinar, Deniz Yilmaz, Demiraslan, Hayati, Duarte, Rafael F., Demeter, Judit, Stanzani, Marta, Melillo, Lorella Maria Antonia, Basilico, Claudia Maria, Cesaro, Simone, Paterno, Giovangiacinto, Califano, Catello, Delia, Mario, Buzzatti, Elisa, Busca, Alessandro, Cornely, Oliver A., Pagano, Livio, Alakel, Nael, Arsenijevi'c, Valentina Arsi'c, Camus, Vincent, Falces-Romero, Iker, Itzhak, Levy, Kouba, Michal, Martino, Rodrigo, Sedlacek, Petr, and Weinbergerova, Barbora
Abstract: Background Our multicentre study aims to identify baseline factors and provide guidance for therapeutic decisions regarding Magnusiomyces-associated infections, an emerging threat in patients with haematological malignancies. Methods HM patients with proven (Magnusiomyces capitatus) M. capitatus or (Magnusiomyces clavatus) M. clavatus (formerly Saprochaete capitata and Saprochaete clavata) infection diagnosed between January 2010 and December 2020 were recorded from the SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group and FungiScope (Global Emerging Fungal Infection Registry). Cases of Magnusiomyces fungemia were compared with candidemia. Results Among 90 Magnusiomyces cases (60 [66%] M. capitatus and 30 (34%) M. clavatus), median age was 50 years (range 2-78), 46 patients (51%) were female and 67 (74%) had acute leukaemia. Thirty-six (40%) of Magnusiomyces-associated infections occurred during antifungal prophylaxis, mainly with posaconazole (n = 13, 36%) and echinocandins (n = 12, 34%). Instead, the candidemia rarely occurred during prophylaxis (p < .0001). First-line antifungal therapy with azoles, alone or in combination, was associated with improved response compared to other antifungals (p = .001). Overall day-30 mortality rate was 43%. Factors associated with higher mortality rates were septic shock (HR 2.696, 95% CI 1.396-5.204, p = .003), corticosteroid treatment longer than 14 days (HR 2.245, 95% CI 1.151-4.376, p = .018) and lack of neutrophil recovery (HR 3.997, 95% CI 2.102-7.601, p < .001). The latter was independently associated with poor outcome (HR 2.495, 95% CI 1.192-5.222, p = .015). Conclusions Magnusiomyces-associated infections are often breakthrough infections. Effective treatment regimens of these infections remain to be determined, but neutrophil recovery appears to play an important role in the favourable outcome.
Published: 2023

28. Nirmatrelvir/ritonavir in COVID-19 patients with haematological malignancies: a report from the EPICOVIDEHA registry

Author: Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Silva, Maria Gomes da, Farina, Francesca, Dávila-Valls, Julio, Bilgin, Yavuz M., Glenthøj, Andreas, Falces-Romero, Iker, Doesum, Jaap van, Labrador, Jorge, Buquicchio, Caterina, El-Ashwah, Shaimaa, Petzer, Verena, Van Praet, Jens, Schönlein, Martin, Dargenio, Michelina, Méndez, Gustavo-Adolfo, Meers, Stef, Itri, Federico, Giordano, Antonio, Pinczés, László Imre, Espigado, Ildefonso, Stojanoski, Zlate, López-García, Alberto, Prezioso, Lucia, Jaksic, Ozren, Vena, Antonio, Fracchiolla, Nicola S., González-López, Tomás José, Čolović, Natasa, Delia, Mario, Weinbergerová, Barbora, Marchetti, Monia, Marqués de Almeida, Joyce, Finizio, Olimpia, Besson, Caroline, Biernat, Monika M., Valković, Toni, Lahmer, Tobias, Cuccaro, Annarosa, Ormazabal-Vélez, Irati, Batinić, Josip, Fernández, Noemí, Jonge, Nick de, Tascini, Carlo, Anastasopoulou, Amalia N., Duléry, Rémy, Príncipe, María Ilaria del, Plantefeve, Gaëtan, Papa, Mario Virgilio, Nucci, Marcio, Jiménez, Moraima, Aujayeb, Avinash, Hernández-Rivas, José Ángel, Merelli, Maria, Cattaneo, Chiara, Blennow, Ola, Nordlander, Anna, Cabirta, Alba, Varricchio, Gina, Sacchi, Maria Vittoria, Córdoba, Raúl, Arellano-Orden, Elena, Gräfe, Stefanie, Wolf, Dominik, Emarah, Ziad, Ammatuna, Emanuele, Hersby, Ditte Stampe, Martín-Pérez, Sonia, Nunes-Rodrigues, Raquel, Rahimli, Laman, Pagano, Livio, Cornely, Oliver A., EPICOVIDEHA registry, Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Silva, Maria Gomes da, Farina, Francesca, Dávila-Valls, Julio, Bilgin, Yavuz M., Glenthøj, Andreas, Falces-Romero, Iker, Doesum, Jaap van, Labrador, Jorge, Buquicchio, Caterina, El-Ashwah, Shaimaa, Petzer, Verena, Van Praet, Jens, Schönlein, Martin, Dargenio, Michelina, Méndez, Gustavo-Adolfo, Meers, Stef, Itri, Federico, Giordano, Antonio, Pinczés, László Imre, Espigado, Ildefonso, Stojanoski, Zlate, López-García, Alberto, Prezioso, Lucia, Jaksic, Ozren, Vena, Antonio, Fracchiolla, Nicola S., González-López, Tomás José, Čolović, Natasa, Delia, Mario, Weinbergerová, Barbora, Marchetti, Monia, Marqués de Almeida, Joyce, Finizio, Olimpia, Besson, Caroline, Biernat, Monika M., Valković, Toni, Lahmer, Tobias, Cuccaro, Annarosa, Ormazabal-Vélez, Irati, Batinić, Josip, Fernández, Noemí, Jonge, Nick de, Tascini, Carlo, Anastasopoulou, Amalia N., Duléry, Rémy, Príncipe, María Ilaria del, Plantefeve, Gaëtan, Papa, Mario Virgilio, Nucci, Marcio, Jiménez, Moraima, Aujayeb, Avinash, Hernández-Rivas, José Ángel, Merelli, Maria, Cattaneo, Chiara, Blennow, Ola, Nordlander, Anna, Cabirta, Alba, Varricchio, Gina, Sacchi, Maria Vittoria, Córdoba, Raúl, Arellano-Orden, Elena, Gräfe, Stefanie, Wolf, Dominik, Emarah, Ziad, Ammatuna, Emanuele, Hersby, Ditte Stampe, Martín-Pérez, Sonia, Nunes-Rodrigues, Raquel, Rahimli, Laman, Pagano, Livio, Cornely, Oliver A., and EPICOVIDEHA registry
Abstract: [Background] Nirmatrelvir/ritonavir treatment decreases the hospitalisation rate in immunocompetent patients with COVID-19, but data on efficacy in patients with haematological malignancy are scarce. Here, we describe the outcome of nirmatrelvir/ritonavir treatment in a large cohort of the latter patients., [Methods] This is a retrospective cohort study from the multicentre EPICOVIDEHA registry (NCT04733729) on patients with haematological malignancy, who were diagnosed with COVID-19 between January and September 2022. Patients receiving nirmatrelvir/ritonavir were compared to those who did not. A logistic regression was run to determine factors associated with nirmatrelvir/ritonavir administration in our sample. Mortality between treatment groups was assessed with Kaplan–Meier survival plots after matching all the patients with a propensity score. Additionally, a Cox regression was modelled to detect factors associated with mortality in patients receiving nirmatrelvir/ritonavir., [Findings] A total of 1859 patients were analysed, 117 (6%) were treated with nirmatrelvir/ritonavir, 1742 (94%) were treated otherwise. Of 117 patients receiving nirmatrelvir/ritonavir, 80% had received ≥1 anti-SARS-CoV-2 vaccine dose before COVID-19 onset, 13% of which received a 2nd vaccine booster. 5% were admitted to ICU. Nirmatrelvir/ritonavir treatment was associated with the presence of extrapulmonary symptoms at COVID-19 onset, for example anosmia, fever, rhinitis, or sinusitis (aOR 2.509, 95%CI 1.448–4.347) and 2nd vaccine booster (aOR 3.624, 95%CI 1.619–8.109). Chronic pulmonary disease (aOR 0.261, 95%CI 0.093–0.732) and obesity (aOR 0.105, 95%CI 0.014–0.776) were not associated with nirmatrelvir/ritonavir use. After propensity score matching, day-30 mortality rate in patients treated with nirmatrelvir/ritonavir was 2%, significantly lower than in patients with SARS-CoV-2 directed treatment other than nirmatrelvir/ritonavir (11%, p = 0.036). No factor was observed explaining the mortality difference in patients after nirmatrelvir/ritonavir administration., [Interpretation] Haematological malignancy patients were more likely to receive nirmatrelvir/ritonavir when reporting extrapulmonary symptoms or 2nd vaccine booster at COVID-19 onset, as opposed to chronic pulmonary disease and obesity. The mortality rate in patients treated with nirmatrelvir/ritonavir was lower than in patients with targeted drugs other than nirmatrelvir/ritonavir.
Published: 2023

29. Molnupiravir compared to nirmatrelvir/ritonavir for COVID-19 in high-risk patients with haematological malignancy in Europe. A matched-paired analysis from the EPICOVIDEHA registry

Author: Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Koehler, Philipp, Weinbergerová, Barbora, Čolović, Natasa, Falces-Romero, Iker, Buquicchio, Caterina, Farina, Francesca, Praet, Jens van, Biernat, Monika M., Itri, Federico, Prezioso, Lucia, Tascini, Carlo, Vena, Antonio, Romano, Alessandra, Delia, Mario, Dávila-Valls, Julio, Martín-Pérez, Sonia, Lavilla-Rubira, Esperanza, Adžić-vukičević, Tatjana, García-Bordallo, Daniel, López-García, Alberto, Criscuolo, Mariana, Petzer, Verena, Fracchiolla, Nicola S., Espigado, Ildefonso, Sili, Uluhan, Meers, Stef, Erben, Nurettin, Cattaneo, Chiara, Tragiannidis, Athanasios, Gavriilaki, Eleni, Schönlein, Martin, Mitrovic, Mirjana, Pantic, Nikola, Merelli, Maria, Labrador, Jorge, Hernández-Rivas, José Ángel, Glenthøj, Andreas, Fouquet, Guillemette, Príncipe, María Ilaria del, Dargenio, Michelina, Calbacho, María, Besson, Caroline, Kohn, Milena, Gräfe, Stefanie, Hersby, Ditte Stampe, Arellano-Orden, Elena, Çolak, Gökçe Melis, Wolf, Dominik, Marchetti, Monia, Nordlander, Anna, Blennow, Ola, Córdoba, Raúl, Mišković, Bojana, Mladenović, Miloš, Bavastro, Martina, Limongelli, Alessandro, Rahimli, Laman, Pagano, Livio, Cornely, Oliver A., Gilead Sciences, Salmanton-García, Jon, Marchesi, Francesco, Koehler, Philipp, Weinbergerová, Barbora, Čolović, Natasa, Falces-Romero, Iker, Buquicchio, Caterina, Farina, Francesca, Praet, Jens van, Biernat, Monika M., Itri, Federico, Prezioso, Lucia, Tascini, Carlo, Vena, Antonio, Romano, Alessandra, Delia, Mario, Dávila-Valls, Julio, Martín-Pérez, Sonia, Lavilla-Rubira, Esperanza, Adžić-vukičević, Tatjana, García-Bordallo, Daniel, López-García, Alberto, Criscuolo, Mariana, Petzer, Verena, Fracchiolla, Nicola S., Espigado, Ildefonso, Sili, Uluhan, Meers, Stef, Erben, Nurettin, Cattaneo, Chiara, Tragiannidis, Athanasios, Gavriilaki, Eleni, Schönlein, Martin, Mitrovic, Mirjana, Pantic, Nikola, Merelli, Maria, Labrador, Jorge, Hernández-Rivas, José Ángel, Glenthøj, Andreas, Fouquet, Guillemette, Príncipe, María Ilaria del, Dargenio, Michelina, Calbacho, María, Besson, Caroline, Kohn, Milena, Gräfe, Stefanie, Hersby, Ditte Stampe, Arellano-Orden, Elena, Çolak, Gökçe Melis, Wolf, Dominik, Marchetti, Monia, Nordlander, Anna, Blennow, Ola, Córdoba, Raúl, Mišković, Bojana, Mladenović, Miloš, Bavastro, Martina, Limongelli, Alessandro, Rahimli, Laman, Pagano, Livio, and Cornely, Oliver A.
Abstract: [Introduction] Molnupiravir and nirmatrelvir/ritonavir are antivirals used to prevent progression to severe SARS-CoV-2 infections and decrease hospitalisation and mortality rates. Nirmatrelvir/ritonavir was authorised in Europe in December 2021, whereas molnupiravir is not yet licensed in Europe as of February 2022. Molnupiravir may be an alternative to nirmatrelvir/ritonavir because it is associated with fewer drug-drug interactions and contraindications. A caveat for molnupiravir is the mode of action induces viral mutations. Mortality rate reduction with molnupiravir was less pronounced than that with nirmatrelvir/ritonavir in patients without haematological malignancy. Little is known about the comparative efficacy of the two drugs in patients with haematological malignancy at high-risk of severe COVID-19. Thus, molnupiravir and nirmatrelvir/ritonavir were compared in a cohort of patients with haematological malignancies., [Methods] Clinical data from patients treated with molnupiravir or nirmatrelvir/ritonavir monotherapy for COVID-19 were retrieved from the EPICOVIDEHA registry. Patients treated with molnupiravir were matched by sex, age (±10 years), and severity of baseline haematological malignancy to controls treated with nirmatrelvir/ritonavir., [Results] A total of 116 patients receiving molnupiravir for the clinical management of COVID-19 were matched to an equal number of controls receiving nirmatrelvir/ritonavir. In each of the groups, 68 (59%) patients were male; with a median age of 64 years (interquartile range [IQR] 53-74) for molnupiravir recipients and 64 years (IQR 54-73) for nirmatrelvir/ritonavir recipients; 56.9% (n=66) of the patients had controlled baseline haematological malignancy, 12.9% (n=15) had stable disease, and 30.2% (n=35) had active disease at COVID-19 onset in each group. During COVID-19 infection, one third of patients from each group were admitted to hospital. Although a similar proportion of patients in the two groups were vaccinated (molnupiravir n=77, 66% vs. nirmatrelvir/ritonavir n=87, 75%), more of those treated with nirmatrelvir/ritonavir had received four vaccine doses (n=27, 23%) compared with those treated with molnupiravir (n=5, 4%) (P<0.001). No differences were detected in COVID-19 severity (P=0.39) or hospitalisation (P=1.0). No statistically significant differences were identified in overall mortality rate (P=0.78) or survival probability (d30 P=0.19, d60 P=0.67, d90 P=0.68, last day of follow up P=0.68). Deaths were either attributed to COVID-19, or the infection was judged by the treating physician to have contributed to death., [Conclusions] Hospitalisation and mortality rates with molnupiravir were comparable to those with nirmatrelvir/ritonavir in high-risk patients with haematological malignancies and COVID-19. Molnupiravir is a plausible alternative to nirmatrelvir/ritonavir for COVID-19 treatment in patients with haematological malignancy.
Published: 2023

30. Azacitidine in the treatment of older patients affected by acute myeloid leukemia: A report by the Rete Ematologica Pugliese (REP)

Author: Delia, Mario, Carluccio, Paola, Buquicchio, Caterina, Vergine, Carolina, Greco, Giuseppina, Amurri, Barbara, Melpignano, Angela, Melillo, Lorella, Cascavilla, Nicola, Guarini, Attilio, Capalbo, Silvana, Tarantini, Giuseppe, Mazza, Patrizio, Pavone, Vincenzo, Di Renzo, Nicola, and Specchia, Giorgina
Published: 2015
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31. PROSPECTIVE MULTICENTER STUDY ON INFECTIOUS COMPLICATIONS AND CLINICAL OUTCOME OF 230 UNFIT ACUTE MYELOID LEUKEMIA PATIENTS RECEIVING FIRST‐LINE THERAPY WITH HYPOMETHYLATING AGENTS ALONE OR IN COMBINATION WITH VENETOCLAX

Author: Candoni, Anna, primary, Lazzarotto, Davide, additional, Papayannidis, Cristina, additional, Piccini, Matteo, additional, Nadali, Giampaolo, additional, Dargenio, Michelina, additional, Riva, Marta, additional, Fracchiolla, Nicola, additional, Mellillo, Lorella, additional, Dragonetti, Giulia, additional, Del Principe, Maria Ilaria, additional, Cattaneo, Chiara, additional, Stulle, Manuela, additional, Pasciolla, Crescenza, additional, De Marchi, Roberta, additional, Delia, Mario, additional, Tisi, Maria Chiara, additional, Bonuomo, Valentina, additional, Sciumè, Mariarita, additional, Spadea, Antonio, additional, Sartor, Chiara, additional, Griguolo, Davide, additional, Buzzatti, Elisa, additional, Basilico, Claudia Maria, additional, Sarlo, Chiara, additional, Piccioni, Anna Lina, additional, Cerqui, Elisa, additional, Lessi, Federica, additional, Olivieri, Attilio, additional, Fanin, Renato, additional, Luppi, Mario, additional, and Pagano, Livio, additional
Published: 2023
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32. Molnupiravir Compared to Nirmatrelvir/Ritonavir for COVID-19 in High-Risk Patients with Haematological Malignancy in Europe. A Matched-Paired Analysis from the Epicovideha Registry

Author: Salmanton-Garcia, Jon, primary, Marchesi, Francesco, additional, Koehler, Philipp, additional, Weinbergerova, Barbora, additional, Čolovic, Natasa, additional, Falces-Romero, Iker, additional, Buquicchio, Caterina, additional, Farina, Francesca, additional, Van Praet, Jens, additional, Biernat, Monika M., additional, Itri, Federico, additional, Prezioso, Lucia, additional, Tascini, Carlo, additional, Vena, Antonio, additional, Romano, Alessandra, additional, Delia, Mario, additional, Davila-Valls, Julio, additional, Martín-Pérez, Sonia, additional, Lavilla-Rubira, Esperanza, additional, Adzic, Tatjana N., additional, Garcia-Bordado, Daniel, additional, Lopez-Garcia, Alberto, additional, Criscuolo, Mariana, additional, Petzer, Verena, additional, Fracchiolla, Nicola S., additional, Espigado, Ildefonso, additional, Sili, Uluhan, additional, Meers, Stef, additional, Erben, Nurettin, additional, Cattaneo, Chiara, additional, Tragiannidis, Athanasios, additional, Gavriilaki, Eleni, additional, Schönlein, Martin, additional, Mitrovic, Mirjana, additional, Pantic, Nikola, additional, Merelli, Maria, additional, Labrador, Jorge, additional, Hernández-Rivas, Jose Angel, additional, Glenthoj, Andreas, additional, Fouquet, Guillemette, additional, del Principe, Maria Ilaria, additional, Dargenio, Michelina, additional, Calbacho, Maria, additional, Besson, Caroline, additional, Kohn, Milena, additional, Grafe, Stefanie K., additional, Hersby, Ditte Stampe, additional, Arellano, Elena, additional, Çolak, Gökçe Melis, additional, Wolf, Dominik, additional, Marchetti, Monia, additional, Nordlander, Anna, additional, Blennow, Ola, additional, Cordoba, Raul, additional, Miskovic, Bojana, additional, Mladenovic, Miloš, additional, Bavastro, Martina, additional, LIMONGELLI, Alessandro, additional, Rahimli, Laman, additional, Pagano, Livio, additional, and Cornely, Oliver A., additional
Published: 2023
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33. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from the EPICOVIDEHA survey

Author: Pagano, Livio, primary, Salmanton-García, Jon, additional, Marchesi, Francesco, additional, Blennow, Ola, additional, Gomes da Silva, Maria, additional, Glenthøj, Andreas, additional, van Doesum, Jaap, additional, Bilgin, Yavuz M., additional, López-García, Alberto, additional, Itri, Federico, additional, Nunes Rodrigues, Raquel, additional, Weinbergerová, Barbora, additional, Farina, Francesca, additional, Dragonetti, Giulia, additional, Berg Venemyr, Caroline, additional, van Praet, Jens, additional, Jaksic, Ozren, additional, Valković, Toni, additional, Falces-Romero, Iker, additional, Martín-Pérez, Sonia, additional, Jiménez, Moraima, additional, Dávila-Valls, Julio, additional, Schönlein, Martin, additional, Ammatuna, Emanuele, additional, Meers, Stef, additional, Delia, Mario, additional, Stojanoski, Zlate, additional, Nordlander, Anna, additional, Lahmer, Tobias, additional, Imre Pinczés, László, additional, Buquicchio, Caterina, additional, Piukovics, Klára, additional, Ormazabal-Vélez, Irati, additional, Fracchiolla, Nicola, additional, Samarkos, Michail, additional, Méndez, Gustavo-Adolfo, additional, Hernández-Rivas, José-Ángel, additional, Espigado, Ildefonso, additional, Cernan, Martin, additional, Petzer, Verena, additional, Lamure, Sylvain, additional, di Blasi, Roberta, additional, Marques de Almedia, Joyce, additional, Dargenio, Michelina, additional, Biernat, Monika M., additional, Sciumè, Mariarita, additional, de Ramón, Cristina, additional, de Jonge, Nick, additional, Batinić, Josip, additional, Aujayeb, Avinash, additional, Marchetti, Monia, additional, Fouquet, Guillemette, additional, Fernández, Noemí, additional, Zambrotta, Giovanni, additional, Sacchi, Maria Vittoria, additional, Guidetti, Anna, additional, Demirkan, Fatih, additional, Prezioso, Lucia, additional, Ráčil, Zdeněk, additional, Nucci, Marcio, additional, Mladenović, Miloš, additional, Liévin, Raphaël, additional, Hanáková, Michaela, additional, Gräfe, Stefanie, additional, Sili, Uluhan, additional, Machado, Marina, additional, Cattaneo, Chiara, additional, Adžić-Vukičević, Tatjana, additional, Verga, Luisa, additional, Labrador, Jorge, additional, Rahimli, Laman, additional, Bonanni, Matteo, additional, Passamonti, Francesco, additional, Pagliuca, Antonio, additional, Corradini, Paolo, additional, Hoenigl, Martin, additional, Koehler, Philipp, additional, Busca, Alessandro, additional, and Cornely, Oliver A., additional
Published: 2022
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34. Multicenter Observational Retrospective Study on Febrile Events in Patients with Acute Myeloid Leukemia Treated with Cpx-351 in 'Real-Life': The SEIFEM Experience

Author: Fianchi, Luana, Guolo, Fabio, Marchesi, Francesco, Cattaneo, Chiara, Gottardi, Michele, Restuccia, Francesco, Candoni, Anna, Ortu La Barbera, Elettra, Fazzi, Rita, Pasciolla, Crescenza, Finizio, Olimpia, Fracchiolla, Nicola, Delia, Mario, Lessi, Federica, Dargenio, Michelina, Bonuomo, Valentina, Del Principe, Maria Ilaria, Zappasodi, Patrizia, Picardi, Marco, Basilico, Claudia, Piedimonte, Monica, Minetto, Paola, Giordano, Antonio, Chiusolo, Patrizia, Prezioso, Lucia, Buquicchio, Caterina, Melillo, Lorella Maria Antonia, Zama, Daniele, Farina, Francesca, Mancini, Valentina, Terrenato, Irene, Rondoni, Michela, Urbino, Irene, Tumbarello, Mario, Busca, Alessandro, and Pagano, Livio
Subjects: febrile events, CPX-351 therapy, secondary acute myeloid leukemia
Published: 2023

35. Clinical features and prognostic factors of Magnusiomyces (Saprochaete) infections in haematology. A multicentre study of SEIFEM/Fungiscope

Author: Weinbergerová, Barbora, Sedlacek, Petr, Martino, Rodrigo, Kouba, Michal, Itzhak, Levy, Falces-Romero, Iker, Camus, Vincent, Arsenijevi'c, Valentina Arsi'c, Alakel, Nael, Pagano, Livio, Cornely, Oliver A., Busca, Alessandro, Buzzatti, Elisa, Delia, Mario, Califano, Catello, Paterno, Giovangiacinto, Cesaro, Simone, Basilico, Claudia Maria, Melillo, Lorella Maria Antonia, Stanzani, Marta, Demeter, Judit, Duarte, Rafael F., Demiraslan, Hayati, Yilmaz Karapinar, Deniz, Spolzino, Angelica, Klimko, Nikolai, Cattaneo, Chiara, Fracchiolla, Nicola, Koehler, Philipp, Nadali, Gianpaolo, Marchesi, Francesco, Piedimonte, Monica, Rácil, Zdenek, Dargenio, Michelina, Criscuolo, Marianna, Seidel, Danila, and Del Principe, Maria Ilaria
Subjects: Adult, Male, Saprochaete, Antifungal Agents, Adolescent, Hematological Malignancies, Diseases, Dermatology, Clavata, Guidelines, Young Adult, Echinocandins, Trichosporon, Humans, Child, Aged, Capitatus, fungal infection, Candidemia, General Medicine, Hematology, Middle Aged, Prognosis, Settore MED/15, Geotrichum, Management, Settore MED/15 - MALATTIE DEL SANGUE, antifungal treatment, Infectious Diseases, Child, Preschool, Magnusiomyces, Invasive Infections, Female, Fungal-Infection
Abstract: © 2022 Wiley-VCH GmbH.Background: Our multicentre study aims to identify baseline factors and provide guidance for therapeutic decisions regarding Magnusiomyces-associated infections, an emerging threat in patients with haematological malignancies. Methods: HM patients with proven (Magnusiomyces capitatus) M. capitatus or (Magnusiomyces clavatus) M. clavatus (formerly Saprochaete capitata and Saprochaete clavata) infection diagnosed between January 2010 and December 2020 were recorded from the SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group and FungiScope (Global Emerging Fungal Infection Registry). Cases of Magnusiomyces fungemia were compared with candidemia. Results: Among 90 Magnusiomyces cases (60 [66%] M. capitatus and 30 (34%) M. clavatus), median age was 50 years (range 2–78), 46 patients (51%) were female and 67 (74%) had acute leukaemia. Thirty-six (40%) of Magnusiomyces-associated infections occurred during antifungal prophylaxis, mainly with posaconazole (n = 13, 36%) and echinocandins (n = 12, 34%). Instead, the candidemia rarely occurred during prophylaxis (p
Published: 2022

36. Postmortem bone marrow analysis in forensic science: Study of 73 cases and review of the literature

Author: Tattoli, Lucia, Tsokos, Michael, Sautter, Julia, Anagnostopoulos, Joannis, Maselli, Eloisa, Ingravallo, Giuseppe, Delia, Mario, and Solarino, Biagio
Published: 2014
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37. Fusariosis in a Patient with Acute Myeloid Leukemia: A Case Report and Review of the Literature

Author: Delia, Mario, Monno, Rosa, Giannelli, Giorgia, Ianora, Amato Antonio Stabile, Dalfino, Lidia, Pastore, Domenico, Capolongo, Carmen, Calia, Carla, Tortorano, Annamaria, and Specchia, Giorgina
Published: 2016
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38. Outcome of infection with omicron SARS‐CoV ‐2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author: Blennow, Ola, primary, Salmanton‐García, Jon, additional, Nowak, Piotr, additional, Itri, Federico, additional, Van Doesum, Jaap, additional, López‐García, Alberto, additional, Farina, Francesca, additional, Jaksic, Ozren, additional, Pinczés, László Imre, additional, Bilgin, Yavuz M., additional, Falces‐Romero, Iker, additional, Jiménez, Moraima, additional, Ormazabal‐Vélez, Irati, additional, Weinbergerová, Barbora, additional, Duléry, Rémy, additional, Stojanoski, Zlate, additional, Lahmer, Tobias, additional, Fernández, Noemí, additional, Hernández‐Rivas, José‐Ángel, additional, Petzer, Verena, additional, De Jonge, Nick, additional, Glenthøj, Andreas, additional, De Ramón, Cristina, additional, Biernat, Monika M., additional, Fracchiolla, Nicola, additional, Aujayeb, Avinash, additional, Van Praet, Jens, additional, Schönlein, Martin, additional, Méndez, Gustavo‐Adolfo, additional, Cattaneo, Chiara, additional, Guidetti, Anna, additional, Sciumè, Mariarita, additional, Ammatuna, Emanuele, additional, Cordoba, Raul, additional, García‐Poutón, Nicole, additional, Gräfe, Stefanie, additional, Cabirta, Alba, additional, Wolf, Dominik, additional, Nordlander, Anna, additional, García‐Sanz, Ramón, additional, Delia, Mario, additional, Berg Venemyr, Caroline, additional, Brones, Clara, additional, Di Blasi, Roberta, additional, De Kort, Elizabeth, additional, Meers, Stef, additional, Lamure, Sylvain, additional, Serrano, Laura, additional, Merelli, Maria, additional, Coppola, Nicola, additional, Bergantim, Rui, additional, Besson, Caroline, additional, Kohn, Milena, additional, Petiti, Jessica, additional, Garcia‐Vidal, Carolina, additional, Dargenio, Michelina, additional, Danion, François, additional, Machado, Marina, additional, Bailén‐Almorox, Rebeca, additional, Hoenigl, Martin, additional, Dragonetti, Giulia, additional, Chai, Louis Yi Ann, additional, Kho, Chi Shan, additional, Bonanni, Matteo, additional, Liévin, Raphaël, additional, Marchesi, Francesco, additional, Cornely, Oliver A., additional, and Pagano, Livio, additional
Published: 2022
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39. High Incidence of Invasive Fungal Diseases in Patients with FLT3-Mutated AML Treated with Midostaurin: Results of a Multicenter Observational SEIFEM Study

Author: Cattaneo, Chiara, primary, Marchesi, Francesco, additional, Terrenato, Irene, additional, Bonuomo, Valentina, additional, Fracchiolla, Nicola Stefano, additional, Delia, Mario, additional, Criscuolo, Marianna, additional, Candoni, Anna, additional, Prezioso, Lucia, additional, Facchinelli, Davide, additional, Pasciolla, Crescenza, additional, Del Principe, Maria Ilaria, additional, Dargenio, Michelina, additional, Buquicchio, Caterina, additional, Mitra, Maria Enza, additional, Farina, Francesca, additional, Borlenghi, Erika, additional, Nadali, Gianpaolo, additional, Gagliardi, Vito Pier, additional, Fianchi, Luana, additional, Sciumè, Mariarita, additional, Menna, Pierantonio, additional, Busca, Alessandro, additional, Rossi, Giuseppe, additional, and Pagano, Livio, additional
Published: 2022
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40. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from the EPICOVIDEHA survey.

Author: Pagano, Livio, Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, Gomes da Silva, Maria, Glenthøj, Andreas, van Doesum, Jaap, Bilgin, Yavuz M, López-García, Alberto, Itri, Federico, Nunes Rodrigues, Raquel, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, van Praet, Jens, Jaksic, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila-Valls, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Imre Pinczés, László, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola, Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José-Ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, di Blasi, Roberta, Marques de Almedia, Joyce, Dargenio, Michelina, Biernat, Monika M, Sciumè, Mariarita, de Ramón, Cristina, de Jonge, Nick, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenović, Miloš, Liévin, Raphaël, Hanáková, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, Cornely, Oliver A, Pagano, Livio, Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, Gomes da Silva, Maria, Glenthøj, Andreas, van Doesum, Jaap, Bilgin, Yavuz M, López-García, Alberto, Itri, Federico, Nunes Rodrigues, Raquel, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, van Praet, Jens, Jaksic, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila-Valls, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Imre Pinczés, László, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola, Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José-Ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, di Blasi, Roberta, Marques de Almedia, Joyce, Dargenio, Michelina, Biernat, Monika M, Sciumè, Mariarita, de Ramón, Cristina, de Jonge, Nick, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenović, Miloš, Liévin, Raphaël, Hanáková, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, and Cornely, Oliver A
Abstract: Limited data are available on breakthrough COVID-19 in patients with hematologic malignancy (HM) after anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. Adult patients with HM, ≥1 dose of anti-SARS-CoV-2 vaccine, and breakthrough COVID-19 between January 2021 and March 2022 were analyzed. A total of 1548 cases were included, mainly lymphoid malignancies (1181 cases, 76%). After viral sequencing in 753 cases (49%), the Omicron variant was prevalent (517, 68.7%). Most of the patients received ≤2 vaccine doses before COVID-19 (1419, 91%), mostly mRNA-based (1377, 89%). Overall, 906 patients (59%) received COVID-19-specific treatment. After 30-day follow-up from COVID-19 diagnosis, 143 patients (9%) died. The mortality rate in patients with the Omicron variant was 7.9%, comparable to other variants, with a significantly lower 30-day mortality rate than in the prevaccine era (31%). In the univariable analysis, older age (P < .001), active HM (P < .001), and severe and critical COVID-19 (P = .007 and P < .001, respectively) were associated with mortality. Conversely, patients receiving monoclonal antibodies, even for severe or critical COVID-19, had a lower mortality rate (P < .001). In the multivariable model, older age, active disease, critical COVID-19, and 2-3 comorbidities were correlated with a higher mortality, whereas monoclonal antibody administration, alone (P < .001) or combined with antivirals (P = .009), was protective. Although mortality is significantly lower than in the prevaccination era, breakthrough COVID-19 in HM is still associated with considerable mortality. Death rate was lower in patients who received monoclonal antibodies, alone or in combination with antivirals.
Published: 2022

41. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author: Blennow, Ola, Salmanton-Garcia, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, Lopez-Garcia, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczes, Laszlo Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jimenez, Moraima, Ormazabal-Velez, Irati, Weinbergerova, Barbora, Dulery, Remy, Stojanoski, Zlate, Lahmer, Tobias, Fernandez, Noemi, Hernandez-Rivas, Jose-angel, Petzer, Verena, De Jonge, Nick, Glenthoj, Andreas, De Ramon, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schonlein, Martin, Mendez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciume, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, Garcia-Pouton, Nicole, Graefe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, Garcia-Sanz, Ramon, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, Francois, Machado, Marina, Bailen-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Lievin, Raphael, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Blennow, Ola, Salmanton-Garcia, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, Lopez-Garcia, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczes, Laszlo Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jimenez, Moraima, Ormazabal-Velez, Irati, Weinbergerova, Barbora, Dulery, Remy, Stojanoski, Zlate, Lahmer, Tobias, Fernandez, Noemi, Hernandez-Rivas, Jose-angel, Petzer, Verena, De Jonge, Nick, Glenthoj, Andreas, De Ramon, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schonlein, Martin, Mendez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciume, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, Garcia-Pouton, Nicole, Graefe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, Garcia-Sanz, Ramon, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, Francois, Machado, Marina, Bailen-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Lievin, Raphael, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio
Published: 2022

42. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies: An EPICOVIDEHA survey report

Author: Gilead Sciences, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Doesum, Jaap van, López-García, Alberto, Farina, Francesca, Jakšić, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, Jonge, Nick de, Glenthøj, Andrea, Ramón, Cristina de, Biernat, Monika, Fracchiolla, Nicola S., Aujayeb, Avinash, Praet, Jens van, Schönlein, Martin, Méndez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Córdoba, Raúl, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, Kort, Elizabeth De, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, García-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Yi Ann Chai, Louis, Shan Kho, Chi, Bonanni, Matteo, Lievin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Gilead Sciences, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Doesum, Jaap van, López-García, Alberto, Farina, Francesca, Jakšić, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, Jonge, Nick de, Glenthøj, Andrea, Ramón, Cristina de, Biernat, Monika, Fracchiolla, Nicola S., Aujayeb, Avinash, Praet, Jens van, Schönlein, Martin, Méndez, Gustavo-Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Córdoba, Raúl, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, Kort, Elizabeth De, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, García-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Yi Ann Chai, Louis, Shan Kho, Chi, Bonanni, Matteo, Lievin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused high mortality in patients with hematological malignancies (HM).1 The newly emerged omicron variants of SARS-CoV-2 harbor multiple novel spike protein mutations that raise concerns about vaccine efficiency and antiviral efficacy of the available therapeutic monoclonal antibodies.2 The first published clinical data in immunocompetent patients have found that infection with omicron variants is associated with reduced vaccine efficiency compared to the delta variants, but decreased hospital admission and mortality.3, 4 Preliminary, prepublished, data from a large case–control study have shown that the vaccine effect against omicron in immunocompromised patients, including HM patients, is even more reduced, but data regarding clinical outcomes are lacking.5 The aim of this study was to describe risk factors, antiviral treatment and outcomes of SARS-CoV-2 omicron variant infection in 593 HM patients included in the EPICOVIDEHA registry.
Published: 2022

43. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies: results from the EPICOVIDEHA survey

Author: Gilead Sciences, Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, Gomes Da Silva, María, Glenthøj, Andrea, Doesum, Jaap van, Bilgin, Yavuz M., López-García, Alberto, Itri, Federico, Nunes-Rodrigues, Raquel, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, Praet, Jens van, Jakšić, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Pinczés, László Imre, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola S., Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José Ángel, Espigado, Ildefonso, Čerňan, Martin, Petzer, Verena, Lamure, Sylvain, Blasi, Roberta di, Marques de Almedia, Joyce, Dargenio, Michelina, Biernat, Monika, Sciumè, Mariarita, Ramón, Cristina de, Jonge, Nick de, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenovic, Milos, Lievin, Raphaël, Hanakova, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, Cornely, Oliver A., Gilead Sciences, Pagano, Livio, Salmanton-García, Jon, Marchesi, Francesco, Blennow, Ola, Gomes Da Silva, María, Glenthøj, Andrea, Doesum, Jaap van, Bilgin, Yavuz M., López-García, Alberto, Itri, Federico, Nunes-Rodrigues, Raquel, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, Praet, Jens van, Jakšić, Ozren, Valković, Toni, Falces-Romero, Iker, Martín-Pérez, Sonia, Jiménez, Moraima, Dávila, Julio, Schönlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Pinczés, László Imre, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-Vélez, Irati, Fracchiolla, Nicola S., Samarkos, Michail, Méndez, Gustavo-Adolfo, Hernández-Rivas, José Ángel, Espigado, Ildefonso, Čerňan, Martin, Petzer, Verena, Lamure, Sylvain, Blasi, Roberta di, Marques de Almedia, Joyce, Dargenio, Michelina, Biernat, Monika, Sciumè, Mariarita, Ramón, Cristina de, Jonge, Nick de, Batinić, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández, Noemí, Zambrotta, Giovanni, Sacchi, Maria Vittoria, Guidetti, Anna, Demirkan, Fatih, Prezioso, Lucia, Ráčil, Zdeněk, Nucci, Marcio, Mladenovic, Milos, Lievin, Raphaël, Hanakova, Michaela, Gräfe, Stefanie, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adžić-Vukičević, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, and Cornely, Oliver A.
Abstract: Limited data are available on breakthrough COVID-19 in patients with hematologic malignancy (HM) after anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. Adult patients with HM, ≥1 dose of anti-SARS-CoV-2 vaccine, and breakthrough COVID-19 between January 2021 and March 2022 were analyzed. A total of 1548 cases were included, mainly lymphoid malignancies (1181 cases, 76%). After viral sequencing in 753 cases (49%), the Omicron variant was prevalent (517, 68.7%). Most of the patients received ≤2 vaccine doses before COVID-19 (1419, 91%), mostly mRNA-based (1377, 89%). Overall, 906 patients (59%) received COVID-19-specific treatment. After 30-day follow-up from COVID-19 diagnosis, 143 patients (9%) died. The mortality rate in patients with the Omicron variant was 7.9%, comparable to other variants, with a significantly lower 30-day mortality rate than in the prevaccine era (31%). In the univariable analysis, older age (P < .001), active HM (P < .001), and severe and critical COVID-19 (P = .007 and P < .001, respectively) were associated with mortality. Conversely, patients receiving monoclonal antibodies, even for severe or critical COVID-19, had a lower mortality rate (P < .001). In the multivariable model, older age, active disease, critical COVID-19, and 2-3 comorbidities were correlated with a higher mortality, whereas monoclonal antibody administration, alone (P < .001) or combined with antivirals (P = .009), was protective. Although mortality is significantly lower than in the prevaccination era, breakthrough COVID-19 in HM is still associated with considerable mortality. Death rate was lower in patients who received monoclonal antibodies, alone or in combination with antivirals.
Published: 2022

44. Outcome of infection with omicron SARS-CoV-2 variant in patients with hematological malignancies:An EPICOVIDEHA survey report

Author: Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, López-García, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, De Jonge, Nick, Glenthøj, Andreas, De Ramón, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schönlein, Martin, Méndez, Gustavo Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Liévin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., Pagano, Livio, Blennow, Ola, Salmanton-García, Jon, Nowak, Piotr, Itri, Federico, Van Doesum, Jaap, López-García, Alberto, Farina, Francesca, Jaksic, Ozren, Pinczés, László Imre, Bilgin, Yavuz M., Falces-Romero, Iker, Jiménez, Moraima, Ormazabal-Vélez, Irati, Weinbergerová, Barbora, Duléry, Rémy, Stojanoski, Zlate, Lahmer, Tobias, Fernández, Noemí, Hernández-Rivas, José Ángel, Petzer, Verena, De Jonge, Nick, Glenthøj, Andreas, De Ramón, Cristina, Biernat, Monika M., Fracchiolla, Nicola, Aujayeb, Avinash, Van Praet, Jens, Schönlein, Martin, Méndez, Gustavo Adolfo, Cattaneo, Chiara, Guidetti, Anna, Sciumè, Mariarita, Ammatuna, Emanuele, Cordoba, Raul, García-Poutón, Nicole, Gräfe, Stefanie, Cabirta, Alba, Wolf, Dominik, Nordlander, Anna, García-Sanz, Ramón, Delia, Mario, Berg Venemyr, Caroline, Brones, Clara, Di Blasi, Roberta, De Kort, Elizabeth, Meers, Stef, Lamure, Sylvain, Serrano, Laura, Merelli, Maria, Coppola, Nicola, Bergantim, Rui, Besson, Caroline, Kohn, Milena, Petiti, Jessica, Garcia-Vidal, Carolina, Dargenio, Michelina, Danion, François, Machado, Marina, Bailén-Almorox, Rebeca, Hoenigl, Martin, Dragonetti, Giulia, Chai, Louis Yi Ann, Kho, Chi Shan, Bonanni, Matteo, Liévin, Raphaël, Marchesi, Francesco, Cornely, Oliver A., and Pagano, Livio
Published: 2022

45. Breakthrough COVID-19 in vaccinated patients with hematologic malignancies:results from EPICOVIDEHA survey

Author: Pagano, Livio, Salmanton-garcía, Jon, Marchesi, Francesco, Blennow, Ola, Gomes Da Silva, Maria, Glenthøj, Andreas, Van Doesum, Jaap A., Bilgin, Yavuz M, Lopez-garcia, Alberto, Itri, Federico, Nunes Rodrigues, Raquel, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, Van Praet, Jens, Jaksic, Ozren, Valkovic, Toni, Falces-romero, Iker, Martin-perez, Sonia, Jiménez, Moraima, Davila-valls, Julio, Schonlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Pinczés, László Imre, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-velez, Irati, Fracchiolla, Nicola Stefano, Samarkos, Michail, Mendez, Gustavo-adolfo, Hernández-rivas, José-ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, Di Blasi, Roberta, Marques De Almeida, Joyce, Dargenio, Michelina, Biernat, Monika Maria, Sciumè, Mariarita, De Ramón, Cristina, De Jonge, Nick Alexander, Batinic, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández Escalada, Noemi, Zambrotta, Giovanni Paolo Maria, Sacchi, Maria Vittoria, Guidetti, Anna, Demirken, Fatih, Prezioso, Lucia, Racil, Zdenek, Nucci, Marcio, Mladenovic, Miloš, Lievin, Raphaël, Hanakova, Michaela, Grafe, Stefanie K, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adzic-vukicevic, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, Cornely, Oliver A., Pagano, Livio, Salmanton-garcía, Jon, Marchesi, Francesco, Blennow, Ola, Gomes Da Silva, Maria, Glenthøj, Andreas, Van Doesum, Jaap A., Bilgin, Yavuz M, Lopez-garcia, Alberto, Itri, Federico, Nunes Rodrigues, Raquel, Weinbergerová, Barbora, Farina, Francesca, Dragonetti, Giulia, Berg Venemyr, Caroline, Van Praet, Jens, Jaksic, Ozren, Valkovic, Toni, Falces-romero, Iker, Martin-perez, Sonia, Jiménez, Moraima, Davila-valls, Julio, Schonlein, Martin, Ammatuna, Emanuele, Meers, Stef, Delia, Mario, Stojanoski, Zlate, Nordlander, Anna, Lahmer, Tobias, Pinczés, László Imre, Buquicchio, Caterina, Piukovics, Klára, Ormazabal-velez, Irati, Fracchiolla, Nicola Stefano, Samarkos, Michail, Mendez, Gustavo-adolfo, Hernández-rivas, José-ángel, Espigado, Ildefonso, Cernan, Martin, Petzer, Verena, Lamure, Sylvain, Di Blasi, Roberta, Marques De Almeida, Joyce, Dargenio, Michelina, Biernat, Monika Maria, Sciumè, Mariarita, De Ramón, Cristina, De Jonge, Nick Alexander, Batinic, Josip, Aujayeb, Avinash, Marchetti, Monia, Fouquet, Guillemette, Fernández Escalada, Noemi, Zambrotta, Giovanni Paolo Maria, Sacchi, Maria Vittoria, Guidetti, Anna, Demirken, Fatih, Prezioso, Lucia, Racil, Zdenek, Nucci, Marcio, Mladenovic, Miloš, Lievin, Raphaël, Hanakova, Michaela, Grafe, Stefanie K, Sili, Uluhan, Machado, Marina, Cattaneo, Chiara, Adzic-vukicevic, Tatjana, Verga, Luisa, Labrador, Jorge, Rahimli, Laman, Bonanni, Matteo, Passamonti, Francesco, Pagliuca, Antonio, Corradini, Paolo, Hoenigl, Martin, Koehler, Philipp, Busca, Alessandro, and Cornely, Oliver A.
Abstract: Limited data have been published on the epidemiology and outcomes of breakthrough COVID-19 in patients with hematological malignancy (HM) after anti-SARS-CoV-2 vaccination. Adult HM who received at least one dose of anti-SARS-CoV-2 vaccine and diagnosed with breakthrough COVID-19 between January 2021 and March 2022 and registered in EPICOVIDEHA were included in this analysis. A total of 1548 cases were included, mainly with lymphoid malignancies (1181 cases, 76%). After viral genome sequencing in 753 cases (49%), Omicron variant was prevalent (517, 68.7%). Most of the patients received at least two vaccine doses before COVID-19 (1419, 91%), mostly mRNA-based (1377, 89%). Overall, 906 patients (59%) received specific treatment for COVID-19. After 30-days follow-up from COVID-19 diagnosis, 143 patients (9%) died. The mortality rate in patients with Omicron variant was of 7.9%, comparable to that reported for the other variants. The 30-day mortality rate was significantly lower than in the pre-vaccine era (31%). In the univariable analysis, older age (p<0.001), active HM (p<0.001), severe and critical COVID-19 (p=0.007 and p<0.001, respectively) were associated with mortality. Conversely, patients receiving monoclonal antibodies, even for severe or critical COVID-19, had a lower mortality rate (p<0.001). In the multivariable model, older age, active disease, critical COVID-19 and at least 2-3 comorbidities were correlated with a higher mortality, whereas the administration of monoclonal antibodies, alone (p<0.001) or combined with antivirals (p=0.009), was observed protective. While mortality is significantly lower than in the pre-vaccination era, breakthrough COVID-19 in HM is still associated with considerable mortality. Death rate was lower in patients who received monoclonal antibodies, alone or in combination with antivirals. EPICOVIDEHA (www.clinicaltrials.gov; National Clinical Trials identifier NCT04733729) is an international open web-based regi
Published: 2022

46. BCR–ABL1 e6a2 transcript in chronic myeloid leukemia: biological features and molecular monitoring by droplet digital PCR

Author: Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Tota, Giuseppina, Casieri, Paola, Cellamare, Angelo, Impera, Luciana, Brunetti, Claudia, Minervini, Angela, Minervini, Crescenzio Francesco, Delia, Mario, Cumbo, Cosimo, Orsini, Paola, Specchia, Giorgina, and Albano, Francesco
Published: 2015
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47. CD3+/Tregs Ratio in Donor Grafts Is Linked to Acute Graft-versus-Host Disease and Immunologic Recovery after Allogeneic Peripheral Blood Stem Cell Transplantation

Author: Pastore, Domenico, Delia, Mario, Mestice, Anna, Carluccio, Paola, Perrone, Tommasina, Gaudio, Francesco, Curci, Paola, Rossi, Antonella Russo, Ricco, Alessandra, and Specchia, Giorgina
Published: 2012
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48. COVID-19 infection in acute lymphoblastic leukemia over 15 months of the pandemic. A Campus ALL report

Author: Chiaretti, Sabina, primary, Bonifacio, Massimiliano, additional, Agrippino, Roberta, additional, Giglio, Fabio, additional, Annunziata, Mario, additional, Curti, Antonio, additional, Principe, Maria Ilaria Del, additional, Salutari, Prassede, additional, Sciumè, Mariarita, additional, Delia, Mario, additional, Armenio, Marco, additional, Mancini, Valentina, additional, Mulè, Antonino, additional, Grimaldi, Francesco, additional, Rege-Cambrin, Giovanna, additional, Santoro, Lidia, additional, Lussana, Federico, additional, Chiusolo, Patrizia, additional, Pasciolla, Crescenza, additional, Scattolin, Anna Maria, additional, Cerrano, Marco, additional, Ciccone, Maria, additional, Defina, Marzia, additional, Forghieri, Fabio, additional, Mazzone, Carla, additional, Piccini, Matteo, additional, Ferrara, Felicetto, additional, Pizzolo, Giovanni, additional, and Foà, Robin, additional
Published: 2022
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49. Deciphering the effects of graft Tregs on chronic graft-versus-host disease: results from a prospective, multicenter study in patients with acute leukemia undergoing allogeneic peripheral blood stem cell transplantation

Author: Delia, Mario, primary, Carluccio, Paola, additional, Gagliardi, Vito Pier, additional, Mestice, Anna, additional, Chiusolo, Patrizia, additional, Arpinati, Mario, additional, Milone, Giulio Antonio, additional, Martino, Massimo, additional, Mazza, Patrizio, additional, Ingrosso, Claudia, additional, Vacca, Adriana, additional, Saporiti, Giorgia, additional, Zallio, Francesco, additional, Attolico, Immacolata, additional, Pastore, Domenico, additional, Specchia, Giorgina, additional, Albano, Francesco, additional, and Musto, Pellegrino, additional
Published: 2022
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50. Clonal Hematopoiesis at the Crossroads of Inflammatory Bowel Diseases and Hematological Malignancies: A Biological Link?

Author: Cumbo, Cosimo, primary, Tarantini, Francesco, additional, Zagaria, Antonella, additional, Anelli, Luisa, additional, Minervini, Crescenzio Francesco, additional, Coccaro, Nicoletta, additional, Tota, Giuseppina, additional, Impera, Luciana, additional, Parciante, Elisa, additional, Conserva, Maria Rosa, additional, Redavid, Immacolata, additional, Carluccio, Paola, additional, Delia, Mario, additional, Giordano, Annamaria, additional, Longo, Maria Chiara, additional, Perrone, Tommasina, additional, Rossi, Antonella Russo, additional, Specchia, Giorgina, additional, Musto, Pellegrino, additional, and Albano, Francesco, additional
Published: 2022
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