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1. Pre-hospital oxygen therapy and saturation variability in COVID-19 patients with and without glucose metabolism disorders: part of the COLOS Study

Author

Bronowicka-Szydełko, Agnieszka, Lewandowski, Łukasz, Lubieniecki, Pawel, Adamiec-Mroczek, Joanna, Doroszko, Adrian, Trocha, Małgorzata, Kujawa, Krzysztof, Matera-Witkiewicz, Agnieszka, Rabczyński, Maciej, Kuźnik, Edwin, Madziarski, Marcin, Sokołowski, Janusz, Jankowska, Ewa A., and Madziarska, Katarzyna

Published
2024
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4. The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study)

Author

Narkiewicz, Krzysztof, Dubiela, Andżelina, Imprialos, Konstantinos, Stavropoulos, Konstantinos, de Freminville, Jean-Baptiste, Azizi, Michel, Cunha, Pedro Guimarães, Lewandowski, Jacek, Strzelczyk, Jakub, Wuerzner, Gregoire, Gosk-Przybyłek, Maria, Szwęch, Elżbieta, Prejbisz, Aleksander, Van der Niepen, Patricia, Kahan, Thomas, Jekell, Andreas, Spaak, Jonas, Tsioufis, Konstantinos, Ehret, Georg, Doroszko, Adrian, Kubalski, Piotr, Polonia, Jorge, Styczkiewicz, Katarzyna, Styczkiewicz, Marek, Mazur, Stanisław, Veglio, Franco, Rabbia, Franco, Eula, Elisabetta, Águila, Fernando Jaen, Sarzani, Riccardo, Spannella, Francesco, Jarai, Zoltan, Papadopoulos, Dimitrios, Sublet, Marilucy Lopez –, Grassos, Charalampos, Kahrimanidis, Ioannis, Gkaliagkousi, Eugenia, Triantafyllou, Areti, Grodzicki, Tomasz, Wizner, Barbara, Seweryn, Aleksandra, Moczulska, Beata, Ntineri, Angeliki, Robles, Nicolas Roberto, Widmiski, Jiri, Zbroch, Edyta, Ostrowska, Aleksandra, Wojciechowska, Wiktoria, Rajzer, Marek, Weber, Thomas, Bursztyn, Michael, Persu, Alexandre, Stergiou, George, Kiełbasa, Grzegorz, Chrostowska, Marzena, Doumas, Michaelis, Parati, Gianfranco, Bilo, Grzegorz, Grassi, Guido, Mancia, Giuseppe, Januszewicz, Andrzej, and Kreutz, Reinhold

Published
2024
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5. Evaluation of Small Vessel Bifurcation Stenting Using the Double‐Kissing Culotte and Culotte Technique in Acute Coronary Syndrome: 12‐Month Clinical Outcomes.

Author

Barycki, Mateusz, Rola, Piotr, Włodarczak, Adrian, Włodarczak, Szymon, Pęcherzewski, Maciej, Włodarczak, Piotr, Jastrzębski, Artur, Furtan, Łukasz, Giniewicz, Andrzej, Doroszko, Adrian, and Lesiak, Maciej

Subjects
ACUTE coronary syndrome, PERCUTANEOUS coronary intervention, MAJOR adverse cardiovascular events, ENDOVASCULAR surgery, MYOCARDIAL infarction
Abstract

Introduction: Patients with small vessels who undergo percutaneous coronary intervention (PCI) with subsequent multiple implantation of drug‐eluting stents remain at a higher risk of unfavorable outcomes. In complex cases where maintaining flow to all side branches is part of contemporary practice, using two‐stent techniques may be appropriate. This study aims to evaluate the efficacy of double‐kissing (DK) culotte technique in comparison to culotte technique in the context of small‐vessel therapy in patients with acute coronary syndrome (ACS). Methods: This substudy of the Lower Silesia culotte Bifurcation Registry retrospectively analyzed patients who underwent ACS‐PCI using DK culotte or culotte technique for bifurcation lesions in small vessels, defined as having at least one branch with a diameter of 2.75 mm or less. The primary endpoint was target lesion failure (TLF), a composite of cardiovascular death, target vessel myocardial infarction, or clinically driven target lesion revascularization (TLR) at 1‐year follow‐up. The secondary endpoint included major adverse cardiac events (MACE). Results: The DK culotte group (n = 49) and the culotte group (n = 52) were compared, with 12‐month follow‐up showing lower TLF in the DK culotte group (8.2% vs. 19.2%, p = 0.082). Similar results were observed for TLR (6.1% vs. 13.5%; p = 0.161), stent restenosis (4.1% vs. 9.6%; p = 0.203), and MACE (18.4% vs. 25%; p = 0.344). Conclusion: For bifurcation lesions with a small‐diameter artery, the DK culotte technique may reduce TLF and MACE compared to the culotte technique. However, given the limited sample size and the absence of statistical significance, these findings remain preliminary and require further investigation. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Usefulness of the CHA 2 DS 2 -VASc Score in Predicting the Outcome in Subjects Hospitalized with COVID-19—A Subanalysis of the COLOS Study.

Author

Resler, Katarzyna, Lubieniecki, Pawel, Zatonski, Tomasz, Doroszko, Adrian, Trocha, Malgorzata, Skarupski, Marek, Kujawa, Krzysztof, Rabczynski, Maciej, Kuznik, Edwin, Bednarska-Chabowska, Dorota, Madziarski, Marcin, Trocha, Tymoteusz, Sokolowski, Janusz, Jankowska, Ewa A., and Madziarska, Katarzyna

Subjects
COVID-19, ACUTE kidney failure, HOSPITAL mortality, HEART failure, STROKE
Abstract

Background: The aim of this study was to see if the CHA2DS2-VASc score (Cardiac failure or dysfunction, Hypertension, Age ≥ 75 [Doubled], Diabetes, Stroke [Doubled]—Vascular disease, Age 65–74 and Sex category [Female] score) could have potential clinical relevance in predicting the outcome of hospitalization time, need for ICU hospitalization, survival time, in-hospital mortality, and mortality at 3 and 6 months after discharge home. Materials: A retrospective analysis of 2183 patients with COVID-19 hospitalized at the COVID-19 Centre of the University Hospital in Wrocław, Poland, between February 2020 and June 2021, was performed. All medical records were collected as part of the COronavirus in LOwer Silesia—the COLOS registry project. The CHA2DS2-VASc score was applied for all subjects, and the patients were observed from admission to hospital until the day of discharge or death. Further information on patient deaths was prospectively collected following the 90 and 180 days after admission. The new risk stratification derived from differences in survival curves and long-term follow-up of our patients was obtained. Primary outcomes measured included in-hospital mortality and 3-month and 6-month all-cause mortality, whereas secondary outcomes included termination of hospitalization from causes other than death (home discharges/transfer to another facility or deterioration/referral to rehabilitation) and non-fatal adverse events during hospitalization. Results: It was shown that gender had no effect on mortality. Significantly shorter hospitalization time was observed in the group of patients with low CHA2DS2-VASc scores. Among secondary outcomes, CHA2DS2-VASc score revealed predictive value in both genders for cardiogenic (5.79% vs. 0.69%; p < 0.0001), stroke/TIA (0.48% vs. 9.92%; p < 0.0001), acute heart failure (0.97% vs. 18.18%; p < 0.0001), pneumonia (43% vs. 63.64%; p < 0.0001), and acute renal failure (7.04% vs. 23.97%; p < 0.0001). This study points at the usefulness of the CHA2DS2-VASc score in predicting the severity of the course of COVID-19. Conclusions: Routine use of this scale in clinical practice may suggest the legitimacy of extending its application to the assessment of not only the risk of thromboembolic events in the COVID-19 cohort. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Comparative short-term outcomes of double-kissing culotte and culotte techniques in acute coronary syndrome: A Multicenter Retrospective Study

Author

Barycki, Mateusz, primary, Włodarczak, Adrian, additional, Rola, Piotr, additional, Włodarczak, Szymon, additional, Pęcherzewski, Maciej, additional, Włodarczak, Piotr, additional, Jastrzębski, Artur, additional, Furtan, Łukasz, additional, Giniewicz, Katarzyna, additional, Doroszko, Adrian, additional, and Lesiak, Maciej, additional

Published
2024
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11. The impact of the COVID-19 Pandemic on hypertension phenotypes (ESH ABPM COVID-19 study)

Author

Ostrowska, A, Wojciechowska, W, Rajzer, M, Weber, T, Bursztyn, M, Persu, A, Stergiou, G, Kiełbasa, G, Chrostowska, M, Doumas, M, Parati, G, Bilo, G, Grassi, G, Mancia, G, Januszewicz, A, Kreutz, R, Narkiewicz, K, Dubiela, A, Imprialos, K, Stavropoulos, K, de Freminville, J, Azizi, M, Cunha, P, Lewandowski, J, Strzelczyk, J, Wuerzner, G, Gosk-Przybyłek, M, Szwęch, E, Prejbisz, A, Van der Niepen, P, Kahan, T, Jekell, A, Spaak, J, Tsioufis, K, Ehret, G, Doroszko, A, Kubalski, P, Polonia, J, Styczkiewicz, K, Styczkiewicz, M, Mazur, S, Veglio, F, Rabbia, F, Eula, E, Águila, F, Sarzani, R, Spannella, F, Jarai, Z, Papadopoulos, D, Sublet, M, Grassos, C, Kahrimanidis, I, Gkaliagkousi, E, Triantafyllou, A, Grodzicki, T, Wizner, B, Seweryn, A, Moczulska, B, Ntineri, A, Robles, N, Widmiski, J, Zbroch, E, Ostrowska, Aleksandra, Wojciechowska, Wiktoria, Rajzer, Marek, Weber, Thomas, Bursztyn, Michael, Persu, Alexandre, Stergiou, George, Kiełbasa, Grzegorz, Chrostowska, Marzena, Doumas, Michaelis, Parati, Gianfranco, Bilo, Grzegorz, Grassi, Guido, Mancia, Giuseppe, Januszewicz, Andrzej, Kreutz, Reinhold, Narkiewicz, Krzysztof, Dubiela, Andżelina, Imprialos, Konstantinos, Stavropoulos, Konstantinos, de Freminville, Jean-Baptiste, Azizi, Michel, Cunha, Pedro Guimarães, Lewandowski, Jacek, Strzelczyk, Jakub, Wuerzner, Gregoire, Gosk-Przybyłek, Maria, Szwęch, Elżbieta, Prejbisz, Aleksander, Van der Niepen, Patricia, Kahan, Thomas, Jekell, Andreas, Spaak, Jonas, Tsioufis, Konstantinos, Ehret, Georg, Doroszko, Adrian, Kubalski, Piotr, Polonia, Jorge, Styczkiewicz, Katarzyna, Styczkiewicz, Marek, Mazur, Stanisław, Veglio, Franco, Rabbia, Franco, Eula, Elisabetta, Águila, Fernando Jaen, Sarzani, Riccardo, Spannella, Francesco, Jarai, Zoltan, Papadopoulos, Dimitrios, Sublet, Marilucy Lopez –, Grassos, Charalampos, Kahrimanidis, Ioannis, Gkaliagkousi, Eugenia, Triantafyllou, Areti, Grodzicki, Tomasz, Wizner, Barbara, Seweryn, Aleksandra, Moczulska, Beata, Ntineri, Angeliki, Robles, Nicolas Roberto, Widmiski, Jiri, Zbroch, Edyta, Ostrowska, A, Wojciechowska, W, Rajzer, M, Weber, T, Bursztyn, M, Persu, A, Stergiou, G, Kiełbasa, G, Chrostowska, M, Doumas, M, Parati, G, Bilo, G, Grassi, G, Mancia, G, Januszewicz, A, Kreutz, R, Narkiewicz, K, Dubiela, A, Imprialos, K, Stavropoulos, K, de Freminville, J, Azizi, M, Cunha, P, Lewandowski, J, Strzelczyk, J, Wuerzner, G, Gosk-Przybyłek, M, Szwęch, E, Prejbisz, A, Van der Niepen, P, Kahan, T, Jekell, A, Spaak, J, Tsioufis, K, Ehret, G, Doroszko, A, Kubalski, P, Polonia, J, Styczkiewicz, K, Styczkiewicz, M, Mazur, S, Veglio, F, Rabbia, F, Eula, E, Águila, F, Sarzani, R, Spannella, F, Jarai, Z, Papadopoulos, D, Sublet, M, Grassos, C, Kahrimanidis, I, Gkaliagkousi, E, Triantafyllou, A, Grodzicki, T, Wizner, B, Seweryn, A, Moczulska, B, Ntineri, A, Robles, N, Widmiski, J, Zbroch, E, Ostrowska, Aleksandra, Wojciechowska, Wiktoria, Rajzer, Marek, Weber, Thomas, Bursztyn, Michael, Persu, Alexandre, Stergiou, George, Kiełbasa, Grzegorz, Chrostowska, Marzena, Doumas, Michaelis, Parati, Gianfranco, Bilo, Grzegorz, Grassi, Guido, Mancia, Giuseppe, Januszewicz, Andrzej, Kreutz, Reinhold, Narkiewicz, Krzysztof, Dubiela, Andżelina, Imprialos, Konstantinos, Stavropoulos, Konstantinos, de Freminville, Jean-Baptiste, Azizi, Michel, Cunha, Pedro Guimarães, Lewandowski, Jacek, Strzelczyk, Jakub, Wuerzner, Gregoire, Gosk-Przybyłek, Maria, Szwęch, Elżbieta, Prejbisz, Aleksander, Van der Niepen, Patricia, Kahan, Thomas, Jekell, Andreas, Spaak, Jonas, Tsioufis, Konstantinos, Ehret, Georg, Doroszko, Adrian, Kubalski, Piotr, Polonia, Jorge, Styczkiewicz, Katarzyna, Styczkiewicz, Marek, Mazur, Stanisław, Veglio, Franco, Rabbia, Franco, Eula, Elisabetta, Águila, Fernando Jaen, Sarzani, Riccardo, Spannella, Francesco, Jarai, Zoltan, Papadopoulos, Dimitrios, Sublet, Marilucy Lopez –, Grassos, Charalampos, Kahrimanidis, Ioannis, Gkaliagkousi, Eugenia, Triantafyllou, Areti, Grodzicki, Tomasz, Wizner, Barbara, Seweryn, Aleksandra, Moczulska, Beata, Ntineri, Angeliki, Robles, Nicolas Roberto, Widmiski, Jiri, and Zbroch, Edyta

Published
2024

13. Insulin and Metformin Administration: Unravelling the Multifaceted Association with Mortality across Various Clinical Settings Considering Type 2 Diabetes Mellitus and COVID-19

Author

Lewandowski, Łukasz, primary, Bronowicka-Szydełko, Agnieszka, additional, Rabczyński, Maciej, additional, Bednarska-Chabowska, Dorota, additional, Adamiec-Mroczek, Joanna, additional, Doroszko, Adrian, additional, Trocha, Małgorzata, additional, Kujawa, Krzysztof, additional, Matera-Witkiewicz, Agnieszka, additional, Kuźnik, Edwin, additional, Lubieniecki, Paweł, additional, Madziarski, Marcin, additional, Sokołowski, Janusz, additional, Jankowska, Ewa A., additional, and Madziarska, Katarzyna, additional

Published
2024
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14. Physical Fitness Is Directly Related to Exercise Capacity and Ventilatory Response to Exercise in Men with HFrEF.

Author

Kisiel-Sekura, Olga, Wójciak, Magdalena, Siennicka, Agnieszka, Tkaczyszyn, Michał, Drozd, Marcin, Jankowska, Ewa A., Doroszko, Adrian, Banasiak, Waldemar, and Węgrzynowska-Teodorczyk, Kinga

Subjects
AEROBIC capacity, PHYSICAL fitness, HEART failure, EXERCISE tests, PATIENT experience
Abstract

Background: Heart failure (HF) patients experience reduced functional fitness level (determining the performance of routine, daily activities) and diminished exercise capacity (linked to more effortful activities). Aim: The aim of the study is to assess this relationship using functional fitness tests compared to peak VO2 and VE/VCO2 slope in the context of exercise capacity and ventilatory response to exercise. Methods: A total of 382 men with stable HFrEF (age: 61 ± 10, NYHA class I/II/III/IV: 16/50/32/2%, LVEF: 30.5 ± 8.3%) underwent cardiopulmonary exercise testing (CPX) and a Senior Fitness Test (SFT). Afterwards, the patients were divided according to the 2capacity with peak VO2 ≥ 18 mL/kg/min, those with higher or lower ventilatory responses (VE/VCO2 slope ≥ 35 vs. <35) to the exercise were compared. Results: Patients who covered shorter distances in the 6 min walking test showed worse results in the functional tests ('stand up and go', 'chair stand' and 'arm curl') and CPX (lower peak VO2, shorter exercise time and higher VE/VCO2 slope). Subjects classified into Class D demonstrated the worst results in all elements of SFT; those in Class A demonstrated the best results. Significant differences that were analogous occurred also between classes B and C. Among the participants who reached peak VO2 ≥ 18 mL/kg/min (n = 170), those with VE/VCO2 slope ≥ 35 were characterized by worse physical fitness as compared to those with VE/VCO2 < 35. Conclusion: Reduced exercise tolerance led to worsening physical function in patients with HFrEF. Moreover, limitations in physical fitness seem to be distinctive for those patients showing excessive ventilatory response to exercise slope VE/VCO2 (≥35). The Senior Fitness Test may be considered as a useful tool for assessing comprehensive functional and clinical status and risk stratification in patients with HFrEF, especially those with extremely low exercise capacity. [ABSTRACT FROM AUTHOR]

Published
2024
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15. The Usefulness of the C 2 HEST Score in Predicting the Clinical Outcomes of COVID-19 in COPD and Non-COPD Cohorts.

Author

Gawryś, Jakub, Doroszko, Adrian, Dróżdż, Olgierd, Trocha, Małgorzata, Gajecki, Damian, Gawryś, Karolina, Szahidewicz-Krupska, Ewa, Rabczyński, Maciej, Kujawa, Krzysztof, Rola, Piotr, Stanek, Agata, Sokołowski, Janusz, Madziarski, Marcin, Jankowska, Ewa Anita, Bronowicka-Szydełko, Agnieszka, Bednarska-Chabowska, Dorota, Kuźnik, Edwin, and Madziarska, Katarzyna

Subjects
COVID-19 pandemic, COVID-19, CHRONIC obstructive pulmonary disease, TREATMENT effectiveness, INTENSIVE care units
Abstract

Patients with chronic obstructive pulmonary disease (COPD) infected with SARS-CoV-2 indicate a higher risk of severe COVID-19 course, which is defined as the need for hospitalization in the intensive care unit, mechanical ventilation, or death. However, simple tools to stratify the risk in patients with COPD suffering from COVID-19 are lacking. The current study aimed to evaluate the predictive value of the C2HEST score in patients with COPD. A retrospective analysis of medical records from 2184 patients hospitalized with COVID-19 at the University Hospital in Wroclaw from February 2020 to June 2021, which was previously used in earlier studies, assessed outcomes such as mortality during hospitalization, all-cause mortality at 3 and 6 months, non-fatal discharge, as well as adverse clinical incidents. This re-analysis specifically examines the outcomes using a COPD split. In the COPD group, 42 deaths were recorded, including 18 in-hospital deaths. In-hospital mortality rates at 3 and 6 months did not significantly differ among C2HEST strata, nor did their impact on subsequent treatment. However, a notable association between the C2HEST score and prognosis was observed in the non-COPD cohort comprising 2109 patients. The C2HEST score's predictive ability is notably lower in COPD patients compared to non-COPD subjects, with COPD itself indicating a high mortality risk. However, C2HEST effectively identifies patients at high risk of cardiac complications during COVID-19, especially in non-COPD cases. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Two-Year Outcomes for Patients with Non-ST-Elevation Acute Coronary Syndrome Treated with Magmaris and Absorb Bioresorbable Scaffolds in Large-Vessel Lesions.

Author

Włodarczak, Adrian, Rola, Piotr, Włodarczak, Szymon, Szudrowicz, Marek, Giniewicz, Katarzyna, Łanocha, Magdalena, Jaroszewska-Pozorska, Joanna, Barycki, Mateusz, Furtan, Łukasz, Kędzierska, Michalina, Włodarczak, Piotr, Doroszko, Adrian, and Lesiak, Maciej

Subjects
ACUTE coronary syndrome, MYOCARDIAL infarction, PERCUTANEOUS coronary intervention, TREATMENT effectiveness, DRUG-eluting stents, THROMBOSIS
Abstract

Background: The acute coronary syndrome (ACS) continues to be a fundamental indication for revascularization by percutaneous coronary intervention (PCI). Drug-eluting stent (DES) implantation remains a part of contemporary practice but permanent caging of the vascular structure with the metallic stent structure may increase the rate of device-related adverse clinical events. As an alternative to classic metallic DESs, the bioresorbable scaffolds (BRSs) have emerged as a temporary vascular support technology. We evaluated the mid-term outcomes of two generations of bioresorbable scaffolds—Absorb (Abbott-Vascular, Chicago, IL, USA) and Magmaris (Biotronik, Germany)—in patients with non-ST-elevation ACS. Methods: The study cohort consisted of 193 subjects after Magmaris implantation and 160 patients following Absorb implantation in large-vessel lesions. Results: At 2 years, a significantly lower rate of a primary outcome (cardiac death, myocardial infarction, stent thrombosis) was observed with Magmaris (5.2% vs. 15%; p = 0.002). In addition, we observed a significantly lower rate of MI in the target vessel (2.6% vs. 9.4%; p = 0.009) and a lower rate of scaffold thrombosis (0% vs. 3.7%; p = 0.008). The TLF rate between the two groups was not significantly different. Conclusion: Magmaris demonstrated a good safety profile and more favorable clinical outcomes when compared to Absorb in patients with non-ST-elevation ACS. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Antiplatelet therapy prior to COVID-19 infection impacts on patients mortality: A propensity score-matched cohort study.

Author

Sokolski, Mateusz, primary, Reszka, Konrad, additional, Adamik, Barbara, additional, Kilis-Pstrusinska, Katarzyna, additional, Lis, Weronika, additional, Pomorski, Michał, additional, Sokolowski, Janusz, additional, Doroszko, Adrian, additional, Madziarska, Katarzyna, additional, Jankowska, Ewa Anita, additional, and Protasiewicz, Marcin, additional

Published
2023
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19. Usefulness of the Veterans Health Administration COVID-19 (VACO) Index for Predicting Short-Term Mortality among Patients of the COLOS Study

Author

Matera-Witkiewicz, Agnieszka, primary, Krupińska, Magdalena, additional, Doroszko, Adrian, additional, Trocha, Małgorzata, additional, Giniewicz, Katarzyna, additional, Kujawa, Krzysztof, additional, Rabczyński, Maciej, additional, Obremska, Marta, additional, Kuznik, Edwin, additional, Lubieniecki, Pawel, additional, Adamik, Barbara, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Madziarski, Marcin, additional, Sokołowski, Janusz, additional, Jankowska, Ewa A., additional, and Madziarska, Katarzyna, additional

Published
2023
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21. Association of serum vitamin D concentration with the final course of hospitalization in patients with COVID-19

Author

Konikowska, Klaudia, primary, Kiliś-Pstrusińska, Katarzyna, additional, Matera-Witkiewicz, Agnieszka, additional, Kujawa, Krzysztof, additional, Adamik, Barbara, additional, Doroszko, Adrian, additional, Kaliszewski, Krzysztof, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Madziarska, Katarzyna, additional, and Jankowska, Ewa Anita, additional

Published
2023
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23. Magnesium bioresorbable scaffold (Magmaris) versus polymer biodegradable ultrathin drug-eluting stent (Ultimaster) in acute coronary syndrome. Mid-term outcomes (2 years).

Author

Włodarczak, Adrian, Rola, Piotr, Włodarczak, Szymon, Szudrowicz, Marek, Jaroszewska-Pozorska, Joanna, Barycki, Mateusz, Furtan, Łukasz, Kędzierska, Michalina, Doroszko, Adrian, and Lesiak, Maciej

Subjects
ACUTE coronary syndrome, BIOABSORBABLE implants, PERCUTANEOUS coronary intervention, MAGNESIUM, MYOCARDIAL infarction, SURGICAL stents
Abstract

Introduction: Acute coronary syndrome (ACS) is a well-known risk factor for adverse clinical outcomes in percutaneous coronary intervention (PCI). Therefore, evaluation of coronary stents in this challenging clinical scenario can provide unique information on device safety and efficacy. Bioresorbable scaffolds (BRS) were designed to overcome long-term complications related to permanent vessel caging with a permanent metallic drug-eluting stent (DES). Aim: We designed this study to evaluate the mid-term safety and efficiency of the Magmaris BRS in comparison to the leading new-generation ultrathin DES Ultimaster in the ACS population. Material and methods: We present a retrospective analysis of 2-year follow-up data. The primary outcomes consisted of death from cardiac causes, myocardial infarction, and in-stent thrombosis. The second main study endpoint was defined as target-lesion failure (TLF). Results: The study population consisted of two cohorts, the first of 193 patients treated with Magmaris implantation and the second of 169 patients treated with Ultimaster implantation. At the 2-year follow-up, there were no significant differences in both study cohorts in terms of primary outcome (5.1% vs. 11%; p = 0.051), and TLF (5.6% vs. 8%, p = 0.41). Conclusions: Treatment with a second-generation BRS (Magmaris) versus a novel second-generation DES (Ultimaster) in non-ST-elevation acute coronary syndrome (NSTE-ACS) was associated with similar rates of target lesion failure at 2-year follow-up. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Retinal arterial remodeling in patients with pheochromocytoma or paraganglioma and its reversibility following surgical treatment

Author

Gosk-Przybyłek, Maria, Doroszko, Adrian, Dobrowolski, Piotr, Warchoł-Celińska, Ewa, Harazny, Joanna, Bińczyk, Ewelina, Szymanek, Katarzyna, Pęczkowska, Mariola, Kabat, Marek, Toutounchi, Sadegh, Gałązka, Zbigniew, Górnicka, Barbara, Szaflik, Jerzy, Januszewicz, Magdalena, Klisiewicz, Anna, Hoffman, Piotr, Lenders, Jacques W.M., Eisenhofer, Graeme, Szaflik, Jacek P., Schmieder, Roland E., Prejbisz, Aleksander, and Januszewicz, Andrzej

Published
2020
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27. Dysnatremia in COVID-19 Patients—An Analysis of the COLOS Study

Author

Królicka, Anna, primary, Letachowicz, Krzysztof, additional, Adamik, Barbara, additional, Doroszko, Adrian, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Kujawa, Krzysztof, additional, Matera-Witkiewicz, Agnieszka, additional, Madziarski, Marcin, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Trocha, Małgorzata, additional, Jankowska, Ewa Anita, additional, and Madziarska, Katarzyna, additional

Published
2023
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29. Orbital atherectomy for treatment of calcified coronary artery lesions. First experiences in Poland: Short-term outcomes of the Lower-Silesia Orbital Atherectomy Registry (LOAR)

Author

Rola, Piotr, primary, Furtan, Łukasz, additional, Włodarczak, Szymon, additional, Jastrzębski, Artur, additional, Barycki, Mateusz, additional, Kędzierska, Michalina, additional, Szudrowicz, Marek, additional, Kulczycki, Jan Jakub, additional, Doroszko, Adrian, additional, Lesiak, Maciej, additional, and Włodarczak, Adrian, additional

Published
2023
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30. Assessment of Clinical Indicators Registered on Admission to the Hospital Related to Mortality Risk in Cancer Patients with COVID-19

Author

Szewczyk-Dąbrowska, Alina, primary, Banasik, Mirosław, additional, Dąbrowska, Krystyna, additional, Kujawa, Krzysztof, additional, Bombala, Wojciech, additional, Sebastian, Agata, additional, Matera-Witkiewicz, Agnieszka, additional, Krupińska, Magdalena, additional, Grata-Borkowska, Urszula, additional, Sokołowski, Janusz, additional, Kiliś-Pstrusińska, Katarzyna, additional, Adamik, Barbara, additional, Doroszko, Adrian, additional, Kaliszewski, Krzysztof, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Jankowska, Ewa A., additional, and Madziarska, Katarzyna, additional

Published
2023
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33. Magnesium Bioresorbable Scaffold (BRS) Magmaris vs Biodegradable Polymer DES Ultimaster in NSTE-ACS Population—12-Month Clinical Outcome

Author

Rola, Piotr, primary, Włodarczak, Adrian, additional, Włodarczak, Szymon, additional, Barycki, Mateusz, additional, Szudrowicz, Marek, additional, Łanocha, Magdalena, additional, Furtan, Łukasz, additional, Woźnica, Katarzyna, additional, Kulczycki, Jan Jakub, additional, Jaroszewska-Pozorska, Joanna, additional, Kędzierska, Michalina, additional, Doroszko, Adrian, additional, and Lesiak, Maciej, additional

Published
2022
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35. Rota-Lithotripsy as a Novel Bail-Out Strategy for Highly Calcified Coronary Lesions in Acute Coronary Syndrome

Author

Rola, Piotr, primary, Furtan, Łukasz, additional, Włodarczak, Szymon, additional, Kulczycki, Jan Jakub, additional, Barycki, Mateusz, additional, Szudrowicz, Marek, additional, Kędzierska, Michalina, additional, Pszonka, Anna, additional, Korus, Justyna, additional, Doroszko, Adrian, additional, Lesiak, Maciej, additional, and Włodarczak, Adrian, additional

Published
2022
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37. The Usefulness of the COVID-GRAM Score in Predicting the Outcomes of Study Population with COVID-19

Author

Sebastian, Agata, primary, Madziarski, Marcin, additional, Madej, Marta, additional, Proc, Krzysztof, additional, Szymala-Pędzik, Małgorzata, additional, Żórawska, Joanna, additional, Gronek, Michał, additional, Morgiel, Ewa, additional, Kujawa, Krzysztof, additional, Skarupski, Marek, additional, Trocha, Małgorzata, additional, Rola, Piotr, additional, Gawryś, Jakub, additional, Letachowicz, Krzysztof, additional, Doroszko, Adrian, additional, Adamik, Barbara, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Matera-Witkiewicz, Agnieszka, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Jankowska, Ewa Anita, additional, and Madziarska, Katarzyna, additional

Published
2022
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39. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds -- magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort.

Author

Włodarczak, Adrian, Rola, Piotr, Barycki, Mateusz, Furtan, Łukasz, Łanocha, Magdalena, Włodarczak, Szymon, Szudrowicz, Marek, Kulczycki, Jan Jakub, Jaroszewska-Pozorska, Joanna, Kędzierska, Michalina, Giniewicz, Katarzyna, Doroszko, Adrian, and Lesiak, Maciej

Subjects
ACUTE coronary syndrome, BIOABSORBABLE implants, TYPE 2 diabetes, PERCUTANEOUS coronary intervention, CORONARY artery disease, DRUG-eluting stents
Abstract

Background: Diabetes type 2 is one of the strongest risk factors affecting coronary artery disease (CAD) and is also a marker of poor short and long-term prognosis in subjects with acute coronary syndrome (ACS) treated with percutaneous coronary intervention (PCI) with subsequent drug-eluting stent (DES) implantation. Chronic local vascular inflammation along with endothelial dysfunction is postulated to be the pathophysiological background of unfavorable results. The second generation of metallic magnesium BRS-Magmaris (Biotronik, Berlin, Germany) had been introduced to clinical practice to overcome these limitations. Methods: We evaluated 2-years clinical outcomes after Magmaris BRS implantation in NSTE-ACS diabetic (n-72) and nondiabetic (n-121) cohorts. Results: No significant differences between diabetic and non-diabetes cohorts were noticed in terms of Primary Outcome (cardiac death, myocardial infarction, stent thrombosis) (8.1% vs 3.3% p = 0.182) and Principal secondary outcome -- TLFtarget lesion failure (9.5% vs 3.3% p = 0.106) at 2-years follow-up. Conclusions: 2-years outcome suggests good safety and efficacy of the magnesium BRS (Magmaris) in NSTE- ACS and concomitant DM. Nevertheless, there is a strong need for large multicenter, randomized, prospective studies for a full assessment of this novel device in diabetic patients with ACS. [ABSTRACT FROM AUTHOR]

Published
2023
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42. Prognostic factors registered on admission to the hospital related to mortality risk in cancer patients with COVID-19: a retrospective cohort study

Author

Szewczyk-Dąbrowska, Alina, primary, Banasik, Mirosław, additional, Dąbrowska, Krystyna, additional, Kujawa, Krzysztof, additional, Bombala, Wojciech, additional, Sebastian, Agata, additional, Matera-Witkiewicz, Agnieszka, additional, Krupińska, Magdalena, additional, Grata-Borkowska, Urszula, additional, Sokołowski, Janusz, additional, Kiliś-Pstrusińska, Katarzyna, additional, Adamik, Barbara, additional, Doroszko, Adrian, additional, Kaliszewski, Krzysztof, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Jankowska, Ewa, additional, and Madziarska, Katarzyna, additional

Published
2022
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43. SARS-CoV-2 Infection and Pregnancy: Maternal and Neonatal Outcomes and Placental Pathology Correlations

Author

Pomorski, Michał, primary, Trzeszcz, Martyna, additional, Matera-Witkiewicz, Agnieszka, additional, Krupińska, Magdalena, additional, Fuchs, Tomasz, additional, Zimmer, Mariusz, additional, Zimmer-Stelmach, Aleksandra, additional, Rosner-Tenerowicz, Anna, additional, Budny-Wińska, Joanna, additional, Tarczyńska-Podraza, Anna, additional, Radziejewska, Klaudia, additional, Królak-Olejnik, Barbara, additional, Szczygieł, Anna, additional, Augustyniak-Bartosik, Hanna, additional, Kuriata-Kordek, Magdalena, additional, Skalec, Karolina, additional, Smoła, Izabela, additional, Morgiel, Ewa, additional, Gawryś, Jakub, additional, Doroszko, Adrian, additional, Rola, Piotr, additional, Trocha, Małgorzata, additional, Kujawa, Krzysztof, additional, Adamik, Barbara, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Jankowska, Ewa A., additional, and Madziarska, Katarzyna, additional

Published
2022
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44. The Usefulness of the C2HEST Risk Score in Predicting Clinical Outcomes among Hospitalized Subjects with COVID-19 and Coronary Artery Disease

Author

Rola, Piotr, primary, Doroszko, Adrian, additional, Trocha, Małgorzata, additional, Gajecki, Damian, additional, Gawryś, Jakub, additional, Matys, Tomasz, additional, Giniewicz, Katarzyna, additional, Kujawa, Krzysztof, additional, Skarupski, Marek, additional, Adamik, Barbara, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Matera-Witkiewicz, Agnieszka, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Madziarski, Marcin, additional, Madej, Marta, additional, Gogolewski, Grzegorz, additional, Chourasia, Goutam, additional, Zielińska, Dorota, additional, Włodarczak, Szymon, additional, Rabczyński, Maciej, additional, Sokołowski, Janusz, additional, Jankowska, Ewa Anita, additional, and Madziarska, Katarzyna, additional

Published
2022
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45. Liver Function Tests in COVID-19: Assessment of the Actual Prognostic Value

Author

Tokarczyk, Urszula, primary, Kaliszewski, Krzysztof, additional, Kopszak, Anna, additional, Nowak, Łukasz, additional, Sutkowska-Stępień, Karolina, additional, Sroczyński, Maciej, additional, Sępek, Monika, additional, Dudek, Agata, additional, Diakowska, Dorota, additional, Trocha, Małgorzata, additional, Gajecki, Damian, additional, Gawryś, Jakub, additional, Matys, Tomasz, additional, Maciejiczek, Justyna, additional, Kozub, Valeriia, additional, Szalast, Roman, additional, Madziarski, Marcin, additional, Zubkiewicz-Zarębska, Anna, additional, Letachowicz, Krzysztof, additional, Kiliś-Pstrusińska, Katarzyna, additional, Matera-Witkiewicz, Agnieszka, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Adamik, Barbara, additional, Kujawa, Krzysztof, additional, Doroszko, Adrian, additional, Madziarska, Katarzyna, additional, and Jankowska, Ewa Anita, additional

Published
2022
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46. Intravascular Lithotripsy as a Novel Treatment Method for Calcified Unprotected Left Main Diseases—Comparison to Rotational Atherectomy—Short-Term Outcomes

Author

Rola, Piotr, primary, Kulczycki, Jan Jakub, additional, Włodarczak, Adrian, additional, Barycki, Mateusz, additional, Włodarczak, Szymon, additional, Szudrowicz, Marek, additional, Furtan, Łukasz, additional, Jastrzębski, Artur, additional, Pęcherzewski, Maciej, additional, Lesiak, Maciej, additional, and Doroszko, Adrian, additional

Published
2022
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48. Usefulness of C2HEST Score in Predicting Clinical Outcomes of COVID-19 in Heart Failure and Non-Heart-Failure Cohorts

Author

Rola, Piotr, primary, Doroszko, Adrian, additional, Trocha, Małgorzata, additional, Giniewicz, Katarzyna, additional, Kujawa, Krzysztof, additional, Gawryś, Jakub, additional, Matys, Tomasz, additional, Gajecki, Damian, additional, Madziarski, Marcin, additional, Zieliński, Stanisław, additional, Skalec, Tomasz, additional, Drobnik, Jarosław, additional, Sebastian, Agata, additional, Zubkiewicz-Zarębska, Anna, additional, Adamik, Barbara, additional, Kaliszewski, Krzysztof, additional, Kiliś-Pstrusinska, Katarzyna, additional, Matera-Witkiewicz, Agnieszka, additional, Pomorski, Michał, additional, Protasiewicz, Marcin, additional, Sokołowski, Janusz, additional, Włodarczak, Szymon, additional, Jankowska, Ewa Anita, additional, and Madziarska, Katarzyna, additional

Published
2022
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49. Outcomes of the two generations of bioresorbable scaffolds (Magmaris vs. Absorb) in acute coronary syndrome in routine clinical practice

Author

Rola, Piotr, primary, Włodarczak, Adrian, additional, Łanocha, Magdalena, additional, Barycki, Mateusz, additional, Szudrowicz, Marek, additional, Kulczycki, Jan J., additional, Jaroszewska-Pozorska, Joanna, additional, Gosiewska, Alicja, additional, Woźnica, Katarzyna, additional, Lesiak, Maciej, additional, and Doroszko, Adrian, additional

Published
2022
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